Kaylene J. Simpson

6.9k citations

110 papers · 4.7k indexed · 1 hit paper · h-index 32

Impact in

Oncology top 1%
- Cancer Cells and Metastasis
- Cancer-related Molecular Pathways
Cancer Research top 2%
- Cancer Genomics and Diagnostics

Papers in

Biophysics 7
- Cell Image Analysis Techniques 7
Immunology and Allergy 6

Co-authors: Geoffrey J. Lindeman Jane E. Visvader Marie-Liesse Asselin-Labat Mark Shackleton Gordon K. Smyth Julia Stingl François Vaillant Li Wu
Journals: Assay and Drug Development Technologies (6 papers)Scientific Data (5 papers)Oncogene (5 papers)Cancer Research (4 papers)Cell Death and Differentiation (4 papers)
Partner nations: Australia United States United Kingdom

In The Last Decade

Kaylene J. Simpson

106 papers receiving 4.6k citations

Hit Papers

align trajectories log scale

Generation of a functional mammary gland from a single stem cell 2006 · 1.5k citations

Peers

Countries citing papers authored by Kaylene J. Simpson

Since Specialization

Citations

This map shows the geographic impact of Kaylene J. Simpson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kaylene J. Simpson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kaylene J. Simpson more than expected).

Fields of papers citing papers by Kaylene J. Simpson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kaylene J. Simpson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kaylene J. Simpson. The network helps show where Kaylene J. Simpson may publish in the future.

Co-authors

The 25 scholars most cited alongside Kaylene J. Simpson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kaylene J. Simpson Line = papers co-authored together Kaylene J. Simpson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing Science Immunology ·Jacki Heraud-Farlow, Scott Taylor, Alistair M. Chalk, Adriana Escudero, Shi-Bin Hu, Ankita Goradia, Tao Sun, Qin Li, Iva Nikolić, Jin Billy Li, Miguel Fidalgo, Diana Guallar, Kaylene J. Simpson, Carl R. Walkley	2024	3
2	RNA kinetics influence the response to transcriptional perturbation in leukaemia cell lines NAR Cancer ·Izabela Todorovski, Mary‐Jane Tsang, Breon Feran, Zheng Fan, Sreeja Gadipally, David Yoannidis, Isabella Y. Kong, Stefan Bjelosevic, S. Rivera, Olivia Voulgaris, Magnus Zethoven, Edwin D. Hawkins, Kaylene J. Simpson, Gisela Mir Arnau, Anthony T. Papenfuss, Ricky W. Johnstone, Stephin J. Vervoort	2024	1
3	A genome-wide CRISPR/Cas9 screen identifies DNA-PK as a sensitiser to ¹⁷⁷Lutetium-DOTA-octreotate radionuclide therapy Theranostics ·Kelly Waldeck, Jessica Van Zuylekom, Carleen Cullinane, Twishi Gulati, Kaylene J. Simpson, Richard W. Tothill, Benjamin J. Blyth, Rodney J. Hicks	2023	6
4	CX-5461 Sensitizes DNA Damage Repair–proficient Castrate-resistant Prostate Cancer to PARP Inhibition Molecular Cancer Therapeutics ·Mitchell G. Lawrence, Laura H. Porter, Nicholas Choo, David Pook, Jeremy Grummet, Carmel Pezaro, Shahneen Sandhu, Susanne Ramm, Jennii Luu, Andrew Bakshi, David L. Goode, Elaine Sanij, Richard B. Pearson, Ross D. Hannan, Kaylene J. Simpson, Renea A. Taylor, Gail P. Risbridger, Luc Furic	2021	17
5	SLC7A11 Is a Superior Determinant of APR-246 (Eprenetapopt) Response than TP53 Mutation Status Molecular Cancer Therapeutics ·Kenji M. Fujihara, Mariana Corrales Benitez, Carlos S. Cabalag, Bonnie Z. Zhang, Hyun Soo Ko, David S. Liu, Kaylene J. Simpson, Ygal Haupt, Lara Lipton, Sue Haupt, Wayne A. Phillips, Nicholas J. Clemons	2021	28
6	Methodology for the identification of small molecule inhibitors of the Fanconi Anaemia ubiquitin E3 ligase complex Scientific Reports ·Michael F. Sharp, Vincent J. Murphy, Sylvie van Twest, Winnie Tan, Jennii Lui, Kaylene J. Simpson, Andrew J. Deans, Wayne Crismani	2020	8
7	Requirement for cleavage factor II _m in the control of alternative polyadenylation in breast cancer cells RNA ·Rachael Emily Turner, Lee Henneken, Marije Liem-Weits, Paul F. Harrison, Angavai Swaminathan, Robert Vary, Iva Nikolić, Kaylene J. Simpson, David Powell, Traude H. Beilharz, Bernhard Dichtl	2020	17
8	A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death EMBO Molecular Medicine ·Sophia Ceder, Sofi Eriksson, Emarndeena H. Cheteh, Swati Dawar, Mariana Corrales Benitez, Vladimir J.N. Bykov, Kenji M. Fujihara, Mélodie Grandin, Xiaodun Li, Susanne Ramm, Corina Behrenbruch, Kaylene J. Simpson, Frédéric Hollande, Lars Abrahmsén, Nicholas J. Clemons, Klas G. Wiman	2020	29
9	Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation Nature Communications ·Xiuquan Ma, Luxi Zhang, Jiangning Song, Elizabeth V. Nguyen, Rachel S. Lee, Samuel J. Rodgers, Fuyi Li, Cheng Huang, Ralf B. Schittenhelm, Howard Chan, Chanly Chheang, Jianmin Wu, Kristin Brown, Christina A. Mitchell, Kaylene J. Simpson, Roger J. Daly	2019	27
10	Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth Cancer Discovery ·Helen Pearson, Jason Li, Valérie S. Méniel, Christina M. Fennell, Paul Waring, Karen G. Montgomery, Richard J. Rebello, Arthi A. Macpherson, Sarah Koushyar, Luc Furic, Carleen Cullinane, Richard Clarkson, Matthew J. Smalley, Kaylene J. Simpson, Toby J. Phesse, Peter R. Shepherd, Patrick O. Humbert, Owen J. Sansom, Wayne A. Phillips	2018	78
11	SBI ² HCS/HCA 3D Imaging: Best Practices and Unmet Needs Colloquium Assay and Drug Development Technologies ·Ann F. Hoffman, Kaylene J. Simpson, Péter Horváth, Carrie J. Lovitt, Serena J. Silver, Evan Easton, Daniel V. LaBarbera, Melissa G. Mendez, M.E. Rothenberg, Jan Seldin, Judith Wardwell-Swanson, Myles Fennell	2017	2
12	A Functional Kinase Short Interfering Ribonucleic Acid Screen Using Protease-Activated Receptor 2-Dependent Opening of Transient Receptor Potential Vanilloid-4 Assay and Drug Development Technologies ·William Darby, Megan S. Grace, Kaylene J. Simpson, Owen L. Woodman, Peter McIntyre	2017	2
13	Signalome-wide assessment of host cell response to hepatitis C virus Nature Communications ·Gholamreza Haqshenas, Jianmin Wu, Kaylene J. Simpson, Roger J. Daly, Hans Netter, Thomas F. Baumert, Christian Doerig	2017	12
14	Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence Assay and Drug Development Technologies ·Keefe T. Chan, Lassi Paavolainen, Katherine M. Hannan, Amee J. George, Ross D. Hannan, Kaylene J. Simpson, Péter Horváth, Richard B. Pearson	2016	8
15	Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin–Deficient Cells Molecular Cancer Therapeutics ·Bryony J. Telford, Augustine Chen, Henry Beetham, James Frick, Tom P. Brew, Cathryn M. Gould, Andrew Single, Tanis Godwin, Kaylene J. Simpson, Parry Guilford	2015	25
16	Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma Clinical Cancer Research ·Ankita Gupte, Emma K. Baker, Soo-San Wan, Elizabeth Stewart, Amos Hong Pheng Loh, Anang A. Shelat, Cathryn M. Gould, Alistair M. Chalk, Scott Taylor, Kurt Lackovic, Åsa Karlström, Anthony J. Mutsaers, Jayesh Desai, Piyush B. Madhamshettiwar, Andrew C.W. Zannettino, Christopher J. Burns, David C.S. Huang, Michael A. Dyer, Kaylene J. Simpson, Carl R. Walkley	2015	54
17	Functional Analysis of Genes in Regions Commonly Amplified in High-Grade Serous and Endometrioid Ovarian Cancer Clinical Cancer Research ·Sally J. Davis, Karen E. Sheppard, Richard B. Pearson, Ian Campbell, Kylie L. Gorringe, Kaylene J. Simpson	2013	51
18	Synthetic lethality between CCNE1 amplification and loss of BRCA1 Proceedings of the National Academy of Sciences ·Dariush Etemadmoghadam, Barbara A. Weir, George Au‐Yeung, Kathryn Alsop, Gillian Mitchell, Joshy George, (unknown), Sally J. Davis, Alan D. D’Andrea, Kaylene J. Simpson, William C. Hahn, David D.L. Bowtell	2013	157
19	A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation Journal of Cell Science ·Amee J. George, Brooke W. Purdue, Cathryn M. Gould, Danièl Thomas, Yanny Handoko, Hongwei Qian, Gregory A. Quaife-Ryan, Kylie A. Morgan, Kaylene J. Simpson, Walter G. Thomas, Ross D. Hannan	2013	32
20	Generation of a functional mammary gland from a single stem cell Cancer Research ·Mark Shackleton, François Vaillant, Kaylene J. Simpson, Julia Stingl, Gordon K. Smyth, Marie-Liesse Asselin-Labat, Li Wu, Jane E. Visvader, Geoffrey J. Lindeman	2006	7

About Kaylene J. Simpson

Kaylene J. Simpson is a scholar working on Biophysics, Immunology and Allergy, Oncology, Molecular Biology and Reproductive Medicine, having authored 110 papers that have together received 4.7k indexed citations. Recurring topics across this work include RNA Research and Splicing (13 papers), Cancer Cells and Metastasis (13 papers), Animal Genetics and Reproduction (8 papers), Cell Image Analysis Techniques (7 papers), RNA modifications and cancer (7 papers), Molecular Biology Techniques and Applications (7 papers), Epigenetics and DNA Methylation (6 papers) and Cellular Mechanics and Interactions (6 papers). The work is most often cited by research in Oncology (1.8k citations), Cancer Research (757 citations), Molecular Biology (2.7k citations), Cell Biology (548 citations) and Immunology and Allergy (203 citations). Kaylene J. Simpson has collaborated with scholars based in Australia, United States and United Kingdom. Frequent co-authors include Geoffrey J. Lindeman, Jane E. Visvader, Marie-Liesse Asselin-Labat, Mark Shackleton, Gordon K. Smyth, Julia Stingl, François Vaillant, Li Wu, Kevin R. Nicholas and Arthur M. Mercurio. Their work appears in journals such as Assay and Drug Development Technologies, Scientific Data, Oncogene, Cancer Research and Cell Death and Differentiation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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