Owen J. Sansom

51.4k total citations · 11 hit papers
311 papers, 23.8k citations indexed

About

Owen J. Sansom is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Owen J. Sansom has authored 311 papers receiving a total of 23.8k indexed citations (citations by other indexed papers that have themselves been cited), including 199 papers in Molecular Biology, 142 papers in Oncology and 57 papers in Cancer Research. Recurrent topics in Owen J. Sansom's work include Wnt/β-catenin signaling in development and cancer (57 papers), Cancer Cells and Metastasis (48 papers) and Genetic factors in colorectal cancer (39 papers). Owen J. Sansom is often cited by papers focused on Wnt/β-catenin signaling in development and cancer (57 papers), Cancer Cells and Metastasis (48 papers) and Genetic factors in colorectal cancer (39 papers). Owen J. Sansom collaborates with scholars based in United Kingdom, United States and Netherlands. Owen J. Sansom's co-authors include Alan R. Clarke, Rachel A. Ridgway, Jennifer P. Morton, Hans Clevers, Nick Barker, Valerie G. Brunton, Dimitris Athineos, Marc van de Wetering, Harry Begthel and Johan H. van Es and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Owen J. Sansom

302 papers receiving 23.5k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Crypt stem cells as the cells-of-origin of intestinal cancer

2008 1.6k citations Rachel A. Ridgway, Alan R. Clarke et al. profile →
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

2009 1.4k citations Valerie G. Brunton, Jennifer P. Morton et al. profile →
Mutant p53 Drives Invasion by Promoting Integrin Recycling

2009 641 citations Brendan Doyle, Ee Hong Tan et al. profile →
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

2004 636 citations Owen J. Sansom, Karen R. Reed et al. profile →
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

2012 582 citations Luke Boulter, Thomas G. Bird et al. profile →
p53 status determines the role of autophagy in pancreatic tumour development

2013 576 citations Mathias T. Rosenfeldt, Jennifer P. Morton et al. profile →
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

2012 562 citations Kevin Myant, Owen J. Sansom et al. The EMBO Journal profile →
The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

2017 479 citations Jennifer P. Morton, Owen J. Sansom et al. profile →
Modulating the therapeutic response of tumours to dietary serine and glycine starvation

2017 420 citations Dimitris Athineos, Gillian Mackay et al. profile →
Hepatic progenitor cells of biliary origin with liver repopulation capacity

2015 345 citations Wei‐Yu Lu, Thomas G. Bird et al. profile →
Therapeutic targeting of tumour myeloid cells

2023 168 citations Simon T. Barry, Owen J. Sansom et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Owen J. Sansom United Kingdom	80	14.4k	8.8k	4.9k	3.5k	2.8k	311	23.8k
Hong Wu United States	89	16.6k 1.2×	7.2k 0.8×	4.5k 0.9×	2.1k 0.6×	3.1k 1.1×	204	26.2k
Jian Yu United States	69	13.5k 0.9×	6.4k 0.7×	3.6k 0.7×	2.3k 0.7×	2.0k 0.7×	262	20.4k
Gerhard Christofori Switzerland	71	12.4k 0.9×	7.1k 0.8×	4.5k 0.9×	2.9k 0.8×	1.7k 0.6×	163	19.6k
Michael J. Birrer United States	83	13.5k 0.9×	9.5k 1.1×	5.1k 1.0×	1.5k 0.4×	3.2k 1.2×	434	25.4k
Lynda Chin United States	82	20.4k 1.4×	9.3k 1.0×	6.7k 1.4×	2.9k 0.8×	2.6k 0.9×	160	29.4k
Thomas Brabletz Germany	65	15.3k 1.1×	10.2k 1.2×	7.5k 1.5×	2.4k 0.7×	2.0k 0.7×	174	23.0k
Nabeel Bardeesy United States	84	19.1k 1.3×	12.0k 1.4×	7.4k 1.5×	3.7k 1.1×	2.8k 1.0×	182	30.8k
Lena Claesson‐Welsh Sweden	87	22.2k 1.5×	6.9k 0.8×	5.8k 1.2×	4.8k 1.4×	3.5k 1.3×	256	32.3k
Eduard Batlle Spain	48	11.7k 0.8×	9.4k 1.1×	3.7k 0.8×	2.3k 0.7×	2.8k 1.0×	87	19.8k
Eric W.‐F. Lam United Kingdom	87	15.3k 1.1×	5.4k 0.6×	4.0k 0.8×	1.7k 0.5×	3.5k 1.3×	298	23.1k

Countries citing papers authored by Owen J. Sansom

Since Specialization

Citations

This map shows the geographic impact of Owen J. Sansom's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Owen J. Sansom with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Owen J. Sansom more than expected).

Fields of papers citing papers by Owen J. Sansom

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Owen J. Sansom. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Owen J. Sansom. The network helps show where Owen J. Sansom may publish in the future.

Co-authorship network of co-authors of Owen J. Sansom

This figure shows the co-authorship network connecting the top 25 collaborators of Owen J. Sansom. A scholar is included among the top collaborators of Owen J. Sansom based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Owen J. Sansom. Owen J. Sansom is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Lee, Colin Y.C., Isaac Dean, Nathan Richoz, et al.. (2025). In Vivo Labeling Resolves Distinct Temporal, Spatial, and Functional Properties of Tumor Macrophages and Identifies Subset-Specific Effects of PD-L1 Blockade. Cancer Immunology Research. 13(9). 1453–1470.

Neerven, Sanne M. van, Nina E. de Groot, Karen-Sue Carlson, et al.. (2022). The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut. Biology Open. 11(12). 8 indexed citations

Patel, Rachana, Catriona A. Ford, Lisa Rodgers, et al.. (2022). Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression. Cancer Research. 82(14). 2565–2575. 20 indexed citations

Swaminathan, Karthic, Andrew D. Campbell, Vassilis Papalazarou, et al.. (2020). The RAC1 Target NCKAP1 Plays a Crucial Role in the Progression of Braf;Pten-Driven Melanoma in Mice. Journal of Investigative Dermatology. 141(3). 628–637.e15. 12 indexed citations

Loveridge, Carolyn J., Ernest Mui, Rachana Patel, et al.. (2017). Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten -Deficient Mouse Model of Prostate Carcinogenesis. Cancer Research. 77(12). 3158–3168. 15 indexed citations

D’Costa, Zenobia, Keaton Jones, Abul Kalam Azad, et al.. (2017). Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer. Cancer Research. 77(21). 5952–5962. 51 indexed citations

Spender, Lindsay C., Gail Ferguson, Sijia Liu, et al.. (2016). Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells. Oncotarget. 7(50). 81995–82012. 18 indexed citations

Driscoll, David R., Saadia A. Karim, Makoto Sano, et al.. (2016). mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer. Cancer Research. 76(23). 6911–6923. 58 indexed citations

Wiegering, Armin, Thomas Jamieson, Melanie Hüttenrauch, et al.. (2015). Targeting Translation Initiation Bypasses Signaling Crosstalk Mechanisms That Maintain High MYC Levels in Colorectal Cancer. Cancer Discovery. 5(7). 768–781. 84 indexed citations

10.

Ueberham, Elke, Beate K. Straub, Daniel Teupser, et al.. (2014). Global Increase of p16INK4a in APC-Deficient Mouse Liver Drives Clonal Growth of p16INK4a-Negative Tumors. Molecular Cancer Research. 13(2). 239–249. 5 indexed citations

11.

Bird, Thomas G., Wei‐Yu Lu, Luke Boulter, et al.. (2013). Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling. Proceedings of the National Academy of Sciences. 110(16). 6542–6547. 132 indexed citations

12.

Nobis, Max, Ewan J. McGhee, Jennifer P. Morton, et al.. (2013). Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer. Cancer Research. 73(15). 4674–4686. 99 indexed citations

13.

Laine, Anni, Harri Sihto, Christophé Côme, et al.. (2013). Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1. Cancer Discovery. 3(2). 182–197. 101 indexed citations

14.

Guest, Rachel V., Luke Boulter, Timothy J. Kendall, et al.. (2013). Cell Lineage Tracing Reveals a Biliary Origin of Intrahepatic Cholangiocarcinoma. Cancer Research. 74(4). 1005–1010. 90 indexed citations

15.

Cordero, Julia B., Rhoda Stefanatos, Alessandro Scopelliti, Marcos Vidal, & Owen J. Sansom. (2012). Inducible progenitor-derived Wingless regulates adult midgut regeneration in Drosophila. The EMBO Journal. 31(19). 3901–3917. 115 indexed citations

16.

Timpson, Paul, Ewan J. McGhee, Jennifer P. Morton, et al.. (2011). Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53. Cancer Research. 71(3). 747–757. 109 indexed citations

17.

Jamieson, Nigel B., Jennifer P. Morton, Asif Ali, et al.. (2011). MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma. Clinical Cancer Research. 18(2). 534–545. 175 indexed citations

18.

Cole, Alicia M., Kevin Myant, Karen R. Reed, et al.. (2010). Cyclin D2–Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss. Cancer Research. 70(20). 8149–8158. 65 indexed citations

19.

Morton, Jennifer P., Paul Timpson, Saadia A. Karim, et al.. (2009). Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer. Proceedings of the National Academy of Sciences. 107(1). 246–251. 465 indexed citations

20.

Méniel, Valérie S., Trevor Hay, Anthony Douglas-Jones, Owen J. Sansom, & Alan R. Clarke. (2005). Mutations in Apc and p53 Synergize to Promote Mammary Neoplasia. Cancer Research. 65(2). 410–416. 14 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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