Karen E. Sheppard

5.0k total citations
68 papers, 2.7k citations indexed

About

Karen E. Sheppard is a scholar working on Molecular Biology, Endocrinology, Diabetes and Metabolism and Oncology. According to data from OpenAlex, Karen E. Sheppard has authored 68 papers receiving a total of 2.7k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Molecular Biology, 24 papers in Endocrinology, Diabetes and Metabolism and 17 papers in Oncology. Recurrent topics in Karen E. Sheppard's work include Hormonal Regulation and Hypertension (24 papers), Melanoma and MAPK Pathways (12 papers) and Adrenal Hormones and Disorders (10 papers). Karen E. Sheppard is often cited by papers focused on Hormonal Regulation and Hypertension (24 papers), Melanoma and MAPK Pathways (12 papers) and Adrenal Hormones and Disorders (10 papers). Karen E. Sheppard collaborates with scholars based in Australia, United States and Sri Lanka. Karen E. Sheppard's co-authors include Grant A. McArthur, John W. Funder, Richard B. Pearson, Ross D. Hannan, Dominic J. Autelitano, Wayne A. Phillips, Kathryn M. Kinross, Benjamin Solomon, Maressa A. Bruhn and Emily J. Lelliott and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Oncology and PLoS ONE.

In The Last Decade

Karen E. Sheppard

68 papers receiving 2.6k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Karen E. Sheppard Australia	27	1.5k	693	584	376	262	68	2.7k
David A. Katz United States	27	1.1k 0.7×	527 0.8×	1.1k 1.8×	222 0.6×	192 0.7×	64	3.4k
Nicoletta Fortunati Italy	34	1.1k 0.8×	494 0.7×	841 1.4×	242 0.6×	239 0.9×	87	2.7k
Andrew D. Darnel Japan	26	568 0.4×	282 0.4×	362 0.6×	311 0.8×	221 0.8×	33	1.8k
Susan K. Logan United States	28	1.8k 1.2×	486 0.7×	266 0.5×	538 1.4×	504 1.9×	64	3.0k
Masanobu Yamada Japan	31	1.1k 0.8×	435 0.6×	1.7k 2.9×	275 0.7×	239 0.9×	208	3.7k
Tiina Jääskeläinen Finland	23	846 0.6×	263 0.4×	234 0.4×	253 0.7×	166 0.6×	68	1.7k
Marie Joseph United States	14	2.3k 1.6×	901 1.3×	245 0.4×	333 0.9×	508 1.9×	19	3.4k
Kerry L. Burnstein United States	36	1.5k 1.0×	565 0.8×	765 1.3×	846 2.3×	584 2.2×	78	3.5k
Angela Alexander United States	22	1.4k 1.0×	367 0.5×	189 0.3×	172 0.5×	293 1.1×	55	2.6k
Christine M. Jewell United States	21	955 0.7×	493 0.7×	927 1.6×	255 0.7×	477 1.8×	29	3.1k

Countries citing papers authored by Karen E. Sheppard

Since Specialization

Citations

This map shows the geographic impact of Karen E. Sheppard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karen E. Sheppard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karen E. Sheppard more than expected).

Fields of papers citing papers by Karen E. Sheppard

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karen E. Sheppard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karen E. Sheppard. The network helps show where Karen E. Sheppard may publish in the future.

Co-authorship network of co-authors of Karen E. Sheppard

This figure shows the co-authorship network connecting the top 25 collaborators of Karen E. Sheppard. A scholar is included among the top collaborators of Karen E. Sheppard based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Karen E. Sheppard. Karen E. Sheppard is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Saleh, Reem, Michael K. Lee, Aparna D. Rao, et al.. (2025). Sensitivity to immune checkpoint inhibitors in BRAF/MEK inhibitor refractory melanoma. Journal for ImmunoTherapy of Cancer. 13(5). e011551–e011551. 2 indexed citations

Smith, Lorey, et al.. (2023). The therapeutic potential of targeting minimal residual disease in melanoma. Clinical and Translational Medicine. 13(3). e1197–e1197. 9 indexed citations

AbuHammad, Shatha, et al.. (2023). PRMT5 and CDK4/6 inhibition result in distinctive patterns of alternative splicing in melanoma. PLoS ONE. 18(11). e0292278–e0292278. 1 indexed citations

Lelliott, Emily J., Karen E. Sheppard, & Grant A. McArthur. (2022). Harnessing the immunotherapeutic potential of CDK4/6 inhibitors in melanoma: is timing everything?. npj Precision Oncology. 6(1). 26–26. 22 indexed citations

Lau, Peter K. H., Carleen Cullinane, Susan Jackson, et al.. (2021). Enhancing Adoptive Cell Transfer with Combination BRAF-MEK and CDK4/6 Inhibitors in Melanoma. Cancers. 13(24). 6342–6342. 6 indexed citations

AbuHammad, Shatha, Alison Slater, Laura Kirby, et al.. (2021). CDK4/6 Inhibition Reprograms Mitochondrial Metabolism in BRAFV600 Melanoma via a p53 Dependent Pathway. Cancers. 13(3). 524–524. 16 indexed citations

Lelliott, Emily J., Grant A. McArthur, Jane Oliaro, & Karen E. Sheppard. (2021). Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma. Frontiers in Immunology. 12. 661737–661737. 39 indexed citations

Lelliott, Emily J., Stefano Mangiola, Kelly M. Ramsbottom, et al.. (2020). Combined BRAF, MEK, and CDK4/6 Inhibition Depletes Intratumoral Immune-Potentiating Myeloid Populations in Melanoma. Cancer Immunology Research. 9(2). 136–146. 15 indexed citations

Yan, Shunfei, Jiachen Xuan, Natalie Brajanovski, et al.. (2020). The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer. British Journal of Cancer. 124(3). 616–627. 29 indexed citations

10.

Son, Jinbae, Katherine M. Hannan, Gretchen Poortinga, et al.. (2020). rDNA Chromatin Activity Status as a Biomarker of Sensitivity to the RNA Polymerase I Transcription Inhibitor CX-5461. Frontiers in Cell and Developmental Biology. 8. 568–568. 17 indexed citations

11.

Khot, Amit, Natalie Brajanovski, Donald P. Cameron, et al.. (2019). First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study. Cancer Discovery. 9(8). 1036–1049. 132 indexed citations

12.

Sheppard, Karen E. & Shatha AbuHammad. (2019). CDK4/6 inhibition in cancer: the cell cycle splicing connection. Molecular & Cellular Oncology. 6(6). e1673643–e1673643. 6 indexed citations

13.

Quin, Jaclyn, Keefe T. Chan, Jennifer R. Devlin, et al.. (2016). Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling. Oncotarget. 7(31). 49800–49818. 79 indexed citations

14.

Wong, Stephen Q., Andreas Behren, Victoria Mar, et al.. (2014). Whole exome sequencing identifies a recurrentRQCD1P131L mutation in cutaneous melanoma. Oncotarget. 6(2). 1115–1127. 25 indexed citations

15.

Sheppard, Karen E., et al.. (2013). Functional Analysis of Genes in Regions Commonly Amplified in High-Grade Serous and Endometrioid Ovarian Cancer. Clinical Cancer Research. 19(6). 1411–1421. 51 indexed citations

16.

Kinross, Kathryn M., Karen E. Sheppard, Richard B. Pearson, & Wayne A. Phillips. (2012). Targeting cancer with PI3K pathway inhibitors: who to aim at?. Translational Cancer Research. 1(2). 119–121. 2 indexed citations

17.

Bruhn, Maressa A., Richard B. Pearson, Ross D. Hannan, & Karen E. Sheppard. (2010). Second AKT: The rise of SGK in cancer signalling. Growth Factors. 28(6). 394–408. 125 indexed citations

18.

Lister, Kevin C., Dominic J. Autelitano, Alicia J. Jenkins, Ross D. Hannan, & Karen E. Sheppard. (2006). Cross talk between corticosteroids and alpha-adrenergic signalling augments cardiomyocyte hypertrophy: A possible role for SGK1. Cardiovascular Research. 70(3). 555–565. 57 indexed citations

19.

Sheppard, Karen E.. (2003). Corticosteroid Receptors, 11β-Hydroxysteroid Dehydrogenase, and the Heart. Vitamins and hormones. 66. 77–112. 24 indexed citations

20.

Sheppard, Karen E.. (1998). Decreased apparent affinity of corticosterone for colonic crypt glucocorticoid receptors is dependent on the cellular milieu and is distinct from corticosterone metabolism. The Journal of Steroid Biochemistry and Molecular Biology. 64(1-2). 35–42. 11 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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