Jen‐Tsan Chi

16.9k citations

146 papers · 11.7k indexed · 4 hit papers · h-index 53

Impact in

Cancer Research top 0.1%
- Cancer, Hypoxia, and Metabolism
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Cancer, Lipids, and Metabolism
Molecular Biology top 0.5%
- RNA modifications and cancer
- Epigenetics and DNA Methylation

Papers in

Cancer Research 56
- Cancer, Hypoxia, and Metabolism 28
- Cancer-related molecular mechanisms research 14
- Cancer, Lipids, and Metabolism 10
Cell Biology 26
- Hippo pathway signaling and YAP/TAZ 13

Co-authors: Patrick O. Brown Howard Y. Chang David Botstein Matt van de Rijn Wen‐Hsuan Yang Jianli Wu Chien‐Kuang Cornelia Ding Chao‐Chieh Lin
Journals: PLoS ONE (9 papers)PLoS Genetics (8 papers)Cancer Research (7 papers)Proceedings of the National Academy of Sciences (6 papers)Nature Communications (4 papers)
Partner nations: United States Taiwan China

In The Last Decade

Jen‐Tsan Chi

140 papers receiving 11.5k citations

Hit Papers

align trajectories log scale

The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma 2019 · 363 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Cell Reports
2004 PLoS Biology
2003 Proceedings of the National Academy of Sciences
2002 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Jen‐Tsan Chi

Since Specialization

Citations

This map shows the geographic impact of Jen‐Tsan Chi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jen‐Tsan Chi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jen‐Tsan Chi more than expected).

Fields of papers citing papers by Jen‐Tsan Chi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jen‐Tsan Chi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jen‐Tsan Chi. The network helps show where Jen‐Tsan Chi may publish in the future.

Co-authors

The 25 scholars most cited alongside Jen‐Tsan Chi, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jen‐Tsan Chi Line = papers co-authored together Jen‐Tsan Chi links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	NINJ1 in Cell Death and Ferroptosis: Implications for Tumor Invasion and Metastasis Cancers ·Ssu-Yu Chen, Ing‐Luen Shyu, Jen‐Tsan Chi	2025	0
2	Structure-guided design and synthesis of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi Proceedings of the National Academy of Sciences ·Patrick A. Dome, Pyeonghwa Jeong, Gibeom Nam, Hongjun Jang, Angela Rivera, Anna Floyd Averette, Eunchong Park, Tzu-Chieh Liao, Maria Ciofani, Jianli Wu, Jen‐Tsan Chi, Ronald A. Venters, Hyunju Park, William J. Steinbach, Praveen R. Juvvadi, Joseph Heitman, Jiyong Hong	2024	0
3	MESH1 knockdown triggers proliferation arrest through TAZ repression Cell Death and Disease ·Tianai Sun, Chien‐Kuang Cornelia Ding, Yuning Zhang, Yang Zhang, Chao‐Chieh Lin, Jianli Wu, Yasaman Setayeshpour, Si’Ana A. Coggins, Caitlin Shepard, Everardo Macias, Baek Kim, Pei Zhou, Raluca Gordân, Jen‐Tsan Chi	2022	7
4	The influence of low‐carbohydrate diets on the metabolic response to androgen‐deprivation therapy in prostate cancer The Prostate ·Jen‐Tsan Chi, Pao‐Hwa Lin, Vladimir Tolstikov, Taofik Oyekunle, Gloria C. Galván, Adela Ramírez‐Torres, Emily Y. Chen, Valerie Bussberg, Bo Chi, Bennett Greenwood, Rangaprasad Sarangarajan, Niven R. Narain, Michael A. Kiebish, Stephen J. Freedland	2021	6
5	27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells Molecular Cancer Research ·Shweta Dambal, Mahmoud A. Alfaqih, Sergio Sanders, Erick Maravilla, Adela Ramírez‐Torres, Gloria C. Galván, Mariana Reis-Sobreiro, Mirja Rotinen, Lucy M. Driver, Matthew S. Behrove, Tijana Jovanović‐Talisman, Junhee Yoon, Sungyong You, James Turkson, Jen‐Tsan Chi, Michael R. Freeman, Everardo Macias, Stephen J. Freedland	2020	44
6	A method to culture human alveolar rhabdomyosarcoma cell lines as rhabdospheres demonstrates an enrichment in stemness and notch signaling Biology Open ·Katherine K. Slemmons, Michael D. Deel, Yi-Tzu Lin, Kristianne M. Oristian, Nina Kuprasertkul, Katia C. Genadry, Po‐Han Chen, Jen‐Tsan Chi, Corinne M. Linardic	2020	4
7	A TAZ–ANGPTL4–NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer Molecular Cancer Research ·Wen‐Hsuan Yang, Zhiqing Huang, Jianli Wu, Chien‐Kuang Cornelia Ding, Susan K. Murphy, Jen‐Tsan Chi	2019	235
8	Hippo pathway effectors YAP/TAZ as novel determinants of ferroptosis Molecular & Cellular Oncology ·Wen‐Hsuan Yang, Jen‐Tsan Chi	2019	60
9	The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma Cell Reports ·Wen‐Hsuan Yang, Chien‐Kuang Cornelia Ding, Tianai Sun, Gabrielle Rupprecht, Chao‐Chieh Lin, David S. Hsu, Jen‐Tsan Chi Hit paper breakdown →	2019	363
10	CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer Cancer Research ·Mahmoud A. Alfaqih, Erik R. Nelson, Wen Liu, Rachid Safi, Jeffery S. Jasper, Everardo Macias, Joseph Geradts, J. Will Thompson, Laura G. Dubois, Michael R. Freeman, Ching‐yi Chang, Jen‐Tsan Chi, Donald P. McDonnell, Stephen J. Freedland	2017	89
11	Glycosylation of KEAP 1 links nutrient sensing to redox stress signaling The EMBO Journal ·Po‐Han Chen, Timothy J. Smith, Jianli Wu, Priscila F. Siesser, Brittany J. Bisnett, Farhan Mohammad Khan, Maxwell Hogue, Erik J. Soderblom, Flora Tang, Jeffrey R. Marks, Michael B. Major, Benjamin M. Swarts, Michael Boyce, Jen‐Tsan Chi	2017	85
12	Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas Cancer Research ·Xiaohu Tang, Jianli Wu, Chien‐Kuang Cornelia Ding, Min Lu, Melissa M. Keenan, Chao‐Chieh Lin, Chih-An Lin, Charles C. Wang, Daniel J. George, David S. Hsu, Jen‐Tsan Chi	2016	67
13	Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Molecular Cancer Therapeutics ·Lihong Mo, Robin E. Bachelder, Margaret Kennedy, Po‐Han Chen, Jen‐Tsan Chi, Andrew Berchuck, George J. Cianciolo, Salvatore V. Pizzo	2015	34
14	Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3–FOXO1-Positive Alveolar Rhabdomyosarcoma Clinical Cancer Research ·Julie J.G. Kephart, Rosanne G.J. Tiller, Lisa E.S. Crose, Katherine K. Slemmons, Po‐Han Chen, Ashley R. Hinson, Rex C. Bentley, Jen‐Tsan Chi, Corinne M. Linardic	2015	20
15	Utilization of the Eμ-Myc Mouse to Model Heterogeneity of Therapeutic Response Molecular Cancer Therapeutics ·Rachel E. Rempel, Xiaolei Jiang, Paul Fullerton, Tuan Zea Tan, Jieru Ye, Jieying Amelia Lau, Seiichi Mori, Jen‐Tsan Chi, Joseph R. Nevins, Daphne R. Friedman	2014	9
16	Associations between Intake of Folate, Methionine, and Vitamins B-12, B-6 and Prostate Cancer Risk in American Veterans SHILAP Revista de lepidopterología ·Adriana C. Vidal, Delores J. Grant, Christina D. Williams, Elizabeth M. Masko, Emma H. Allott, Kathryn Shuler, Megan McPhail, Alexis R. Gaines, Elizabeth Calloway, Leah Gerber, Jen‐Tsan Chi, Stephen J. Freedland, Cathrine Hoyo	2012	22
17	Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality Science Translational Medicine ·Denise A. Chan, Patrick D. Sutphin, Phuong Nguyen, Sandra Turcotte, Edwin W. Lai, Alice Banh, Gloria E. Reynolds, Jen‐Tsan Chi, Jason Wu, David E. Solow-Cordero, Muriel Bonnet, Jack U. Flanagan, Donna M. Bouley, Edward E. Graves, William A. Denny, Michael P. Hay, Amato J. Giaccia	2011	456
18	Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs Cancer Research ·Xiaohu Tang, Joseph E. Lucas, Julia Ling-Yu Chen, Gregory LaMonte, Jianli Wu, Michael Changsheng Wang, Constantinos Koumenis, Jen‐Tsan Chi	2011	86
19	Comparison of Genomics and Functional Imaging from Canine Sarcomas Treated with Thermoradiotherapy Predicts Therapeutic Response and Identifies Combination Therapeutics Clinical Cancer Research ·Jen‐Tsan Chi, Donald Ε. Thrall, J Chen, Stacey A. Snyder, Diane Fels, Chelsea D. Landon, Linda McCall, Lan Lan, Marlene Hauck, James R. MacFall, Benjamin L. Viglianti, Mark W. Dewhirst	2011	27
20	Genomewide view of gene silencing by small interfering RNAs Proceedings of the National Academy of Sciences ·Jen‐Tsan Chi, Howard Y. Chang, Nancy Wang, Dustin S. Chang, Nina Dunphy, Patrick O. Brown	2003	220

About Jen‐Tsan Chi

Jen‐Tsan Chi is a scholar working on Cancer Research, Cell Biology, Molecular Biology, Biochemistry and Hematology, having authored 146 papers that have together received 11.7k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (28 papers), RNA modifications and cancer (27 papers), Ferroptosis and cancer prognosis (16 papers), Epigenetics and DNA Methylation (14 papers), Cancer-related molecular mechanisms research (14 papers), Hippo pathway signaling and YAP/TAZ (13 papers), Cancer, Lipids, and Metabolism (10 papers) and RNA Research and Splicing (10 papers). The work is most often cited by research in Cancer Research (4.6k citations), Molecular Biology (7.1k citations), Oncology (1.8k citations), Pulmonary and Respiratory Medicine (2.0k citations) and Cell Biology (1.0k citations). Jen‐Tsan Chi has collaborated with scholars based in United States, Taiwan and China. Frequent co-authors include Patrick O. Brown, Howard Y. Chang, David Botstein, Matt van de Rijn, Wen‐Hsuan Yang, Jianli Wu, Chien‐Kuang Cornelia Ding, Chao‐Chieh Lin, Marilyn J. Telen and Carolyn Sangokoya. Their work appears in journals such as PLoS ONE, PLoS Genetics, Cancer Research, Proceedings of the National Academy of Sciences and Nature Communications.

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