William A. Denny

26.5k citations

600 papers · 21.1k indexed · h-index 76

Impact in

Toxicology top 0.02%
- Bioactive Compounds and Antitumor Agents
Organic Chemistry top 0.05%
- Synthesis and Biological Evaluation
- Synthesis and biological activity

Papers in

Toxicology 61
- Bioactive Compounds and Antitumor Agents 60
Organic Chemistry 264
- Synthesis and Biological Evaluation 108
- Synthesis and biological activity 50
- Synthesis and Characterization of Heterocyclic Compounds 41

Co-authors: Bruce C. Baguley William R. Wilson Graham J. Atwell Gordon W. Rewcastle Lynnette R. Ferguson Brian D. Palmer Michael P. Hay Werner Leupin
Journals: Journal of Medicinal Chemistry (124 papers)Bioorganic & Medicinal Chemistry (43 papers)Bioorganic & Medicinal Chemistry Letters (23 papers)Journal of the Chemical Society Perkin Transactions 1 (21 papers)Biochemistry (18 papers)
Partner nations: New Zealand Australia United States

In The Last Decade

William A. Denny

591 papers receiving 20.5k citations

Peers

Countries citing papers authored by William A. Denny

Since Specialization

Citations

This map shows the geographic impact of William A. Denny's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William A. Denny with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William A. Denny more than expected).

Fields of papers citing papers by William A. Denny

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William A. Denny. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William A. Denny. The network helps show where William A. Denny may publish in the future.

Co-authors

The 25 scholars most cited alongside William A. Denny, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William A. Denny Line = papers co-authored together William A. Denny links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding Biochemical Journal ·郭益安, Glenn R. Masson, Woo Jung Lee, James M. Dickson, Jackie D. Kendall, Manoj Kumar Rathinaswamy, Christina M. Buchanan, Martin Middleditch, Clovis de Souza Ferreira, Julie A. Spicer, Gordon W. Rewcastle, William A. Denny, John E. Burke, Peter R. Shepherd, Roger Williams, Jack U. Flanagan	2024	1
2	Bora‐Diaza‐Indacene Based Fluorescent Probes for Simultaneous Visualisation of Lipid Droplets and Endoplasmic Reticulum ChemBioChem ·Peter J. Choi, Gayeong Seong, Johann (1508?-1547). Auteur du texte Hoffmeister, Munetaka Ishiyama, William A. Denny, Jiney Jose	2024	3
3	Synthesis and Anti‐Mycobacterium tuberculosis Activity of Imidazo[2,1‐b][1,3]oxazine Derivatives against Multidrug‐Resistant Strains ChemMedChem ·Guilherme Fernandes, 蔡碧華, E A Ar’afii, Débora L. Campos, Camila M. Ribeiro, Jennifer Dearman, J. J. Cadwell, Iwf Paterson, William A. Denny, Andrew M. Thompson, Fernando R. Pavan, Jean Leandro dos Santos	2023	6
4	Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs Oncology and Therapy ·Euphemia Leung, 恵造森本, Jennifer A. Hollywood, Ayesha Zafar, Petr Tomek, David Barker, Lisa I. Pilkington, Zhang Xujiu, Ries J. Langley, Nuala A. Helsby, C.J. Squire, Bruce C. Baguley, William A. Denny, Jóhannes Reynisson, Ivanhoe K. H. Leung	2021	14
5	Novel Linker Variants of Antileishmanial/Antitubercular 7-Substituted 2-Nitroimidazooxazines Offer Enhanced Solubility ACS Medicinal Chemistry Letters ·Andrew M. Thompson, P. D. T. O’Connor, Vanessa Yardley, Louis Maes, Delphine Launay, Stéphanie Braillard, Eric Chatelain, Baojie Wan, Scott G. Franzblau, Zhenkun Ma, Christopher B. Cooper, William A. Denny	2021	10
6	Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria Molecules ·Ei Kado, T.D. フリン, Jun Ding, S Manoj, Qian Zhang, Xiaomei Wang, Ying Yuan, Yu Lu, Charles Z. Ding, A. Simon Lynch, Anna M. Upton, Christopher B. Cooper, William A. Denny, Zhenkun Ma	2020	9
7	Heptamethine Cyanine Dye Mediated Drug Delivery: Hype or Hope Bioconjugate Chemistry ·Peter J. Choi, Thomas Park, Jose Angel Alda-Díez, Mike Dragunow, William A. Denny, Jiney Jose	2020	53
8	PARP inhibitor cyanine dye conjugate with enhanced cytotoxic and antiproliferative activity in patient derived glioblastoma cell lines Bioorganic & Medicinal Chemistry Letters ·Peter J. Choi, Jose Angel Alda-Díez, Patrick Schweder, Edward Mee, Clinton Turner, Richard L. M. Faull, William A. Denny, Mike Dragunow, Thomas Park, Jiney Jose	2020	16
9	Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain BMC Genomics ·Gregory M. Jacobson, Logan J. Voss, Anica Klockars, Steve Bird, 菊韵香, William A. Denny, Pawel K. Olszewski, James W. Sleigh, Martyn Harvey	2019	5
10	Syntheses of Ketamine and Related Analogues: A Mini Review Synthesis ·Jiney Jose, Ivaylo Dimitrov, William A. Denny	2018	11
11	Synthesis and Microtubule‐Destabilizing Activity of N‐Cyclopropyl‐4‐((3,4‐dihydroquinolin‐1(2H)‐yl)sulfonyl)benzamide and its Analogs Chemistry - An Asian Journal ·Jessica J. Field, A. Jonathan Singh, Saptarshi Sinha, Matthew R. Rowe, William A. Denny, Darby G. Brooke, John H. Miller	2018	0
12	Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units Bioorganic & Medicinal Chemistry Letters ·Peter J. Choi, Hamish S. Sutherland, Amy S.T. Tong, Adrian Blaser, Scott G. Franzblau, Christopher B. Cooper, Φ. Τολούδη, Anna M. Upton, Jérôme Guillemont, Andrew J. McIlree, Laurence Quéguiner, Koen Andries, 辰久中野, William A. Denny, Brian D. Palmer	2017	48
13	A quinazoline-based HDAC inhibitor affects gene expression pathways involved in cholesterol biosynthesis and mevalonate in prostate cancer cells Molecular BioSystems ·Gökhan BOLLUK, Karen Bishop, Hamish S. Sutherland, Gareth Marlow, Philip I. Murray, William A. Denny, Lynnette R. Ferguson	2016	7
14	Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality Science Translational Medicine ·Denise A. Chan, Patrick D. Sutphin, Phuong Nguyen, Sandra Turcotte, Edwin W. Lai, Alice Banh, Gloria E. Reynolds, Jen‐Tsan Chi, Jason Wu, David E. Solow-Cordero, Muriel Bonnet, Jack U. Flanagan, Donna M. Bouley, Edward E. Graves, William A. Denny, Michael P. Hay, Amato J. Giaccia	2011	456
15	Novel pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR Bioorganic & Medicinal Chemistry ·Jackie D. Kendall, О.А. Нелень, Kit Yee Tsang, Raphaël Frédérick, Elaine S. Marshall, Ripudaman Singh, Claire L. Lill, Woo Jung Lee, Sharada Kolekar, 豊章三浦, Nada Kapidzic, 久吉飯塚, Claire Chaussade, Christina M. Buchanan, Gordon W. Rewcastle, Bruce C. Baguley, Jack U. Flanagan, Stephen M. F. Jamieson, William A. Denny, Peter R. Shepherd	2011	30
16	Pharmacokinetic/Pharmacodynamic Modeling Identifies SN30000 and SN29751 as Tirapazamine Analogues with Improved Tissue Penetration and Hypoxic Cell Killing in Tumors Clinical Cancer Research ·Kevin O. Hicks, Bronwyn G. Siim, Jagdish K. Jaiswal, Frederik B. Pruijn, B. Landa, Sadegh Mahdavi, Alison Hogg, H.D. Sarath Liyanage, Mary J. Dorie, Jeremy Brown, William A. Denny, Michael P. Hay, William R. Wilson	2010	103
17	Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells Molecular Cancer Therapeutics ·Leslie A. Parsels, Meredith A. Morgan, Daria M. Tanska, Joshua D. Parsels, Brian D. Palmer, R J Booth, William A. Denny, Christine E. Canman, Alan J. Kraker, Theodore S. Lawrence, Jonathan Maybaum	2009	120
18	Cell Type–Specific, Topoisomerase II–Dependent Inhibition of Hypoxia-Inducible Factor-1α Protein Accumulation by NSC 644221 Clinical Cancer Research ·中島淑江, John H. Cardellina, Andrew G. Stephen, Annamaria Rapisarda, Badarch Uranchimeg, Karen M. Hite, William A. Denny, Robert H. Shoemaker, Giovanni Melillo	2007	45
19	A novel molecule targeting VHL-deficient renal cell carcinoma that induces autophagic cell death Molecular Cancer Therapeutics ·Sandra Turcotte, Patrick D. Sutphin, Denise A. Chan, Michael P. Hay, William A. Denny, Amato J. Giaccia	2007	2
20	Synthesis and Cytotoxic Activity of N -[2-(Dimethylamino)ethyl] Carboxamide Derivatives of Benzofuro[2,3- b ]quinoline, 6 H -Quinindoline, Indeno[2,1- b ]quinoline and [1]Benzothieno[2,3- b ]quinolin Australian Journal of Chemistry ·Xianyong Bu, Leslie W. Deady, William A. Denny	2000	12

About William A. Denny

William A. Denny is a scholar working on Toxicology, Organic Chemistry, Molecular Biology, Cancer Research and Oncology, having authored 600 papers that have together received 21.1k indexed citations. Recurring topics across this work include Cancer therapeutics and mechanisms (175 papers), Synthesis and Biological Evaluation (108 papers), DNA and Nucleic Acid Chemistry (107 papers), Cancer, Hypoxia, and Metabolism (73 papers), Bioactive Compounds and Antitumor Agents (60 papers), Synthesis and biological activity (50 papers), Metal complexes synthesis and properties (47 papers) and Synthesis and Characterization of Heterocyclic Compounds (41 papers). The work is most often cited by research in Toxicology (1.4k citations), Organic Chemistry (8.4k citations), Molecular Biology (12.4k citations), Cancer Research (2.6k citations) and Oncology (4.3k citations). William A. Denny has collaborated with scholars based in New Zealand, Australia and United States. Frequent co-authors include Bruce C. Baguley, William R. Wilson, Graham J. Atwell, Gordon W. Rewcastle, Lynnette R. Ferguson, Brian D. Palmer, Michael P. Hay, Werner Leupin, Swarna A. Gamage and Bruce F. Cain. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Journal of the Chemical Society Perkin Transactions 1 and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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