Donald P. McDonnell

30.2k citations

272 papers · 23.8k indexed · 8 hit papers · h-index 88

Molecular Biology top 0.2%
Genetics top 0.02%
Oncology top 0.5%
Cancer Research top 0.2%
Endocrinology, Diabetes and Metabolism top 0.2%

Co-authors: John D. Norris Julie M. Hall Ching‐yi Chang Suzanne E. Wardell Kevin W. Gaido Erik R. Nelson Rachid Safi Mark E. Goldman
Topics: Estrogen and related hormone effects (161 papers)Retinoids in leukemia and cellular processes (38 papers)Prostate Cancer Treatment and Research (24 papers)
Cited by: Genetics Cancer Research Endocrinology, Diabetes and Metabolism
Journals: Science Cell Proceedings of the National Academy of Sciences
Partner nations: United States Canada United Kingdom

In The Last Decade

Donald P. McDonnell

266 papers receiving 23.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Estrogen Receptor β-Isoform (ERβ) of the Human Estrogen Receptor Modulates ERα Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens1

1999 866 citations Julie M. Hall, Donald P. McDonnell Endocrinology profile →
Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 783 citations Donald P. McDonnell et al. Proceedings of the National Academy of Sciences profile →
27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology

2013 632 citations Erik R. Nelson, Suzanne E. Wardell et al. Science profile →
Evaluation of Chemicals with Endocrine Modulating Activity in a Yeast-Based Steroid Hormone Receptor Gene Transcription Assay

1997 568 citations Donald P. McDonnell et al. profile →
Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.

1994 545 citations Donald P. McDonnell et al. Molecular Endocrinology profile →
The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

2017 298 citations Suzanne E. Wardell, Ching‐yi Chang et al. profile →
Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer

2021 231 citations Wen Liu, Rachid Safi et al. profile →
Estrogen Receptor Signaling in the Immune System

2022 142 citations Ching‐yi Chang, Donald P. McDonnell et al. profile →

Peers

Countries citing papers authored by Donald P. McDonnell

Since Specialization

Citations

This map shows the geographic impact of Donald P. McDonnell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Donald P. McDonnell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Donald P. McDonnell more than expected).

Fields of papers citing papers by Donald P. McDonnell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Donald P. McDonnell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Donald P. McDonnell. The network helps show where Donald P. McDonnell may publish in the future.

Co-authorship network of co-authors of Donald P. McDonnell

This figure shows the co-authorship network connecting the top 25 collaborators of Donald P. McDonnell. A scholar is included among the top collaborators of Donald P. McDonnell based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Donald P. McDonnell. Donald P. McDonnell is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling 2025 ·npj Breast Cancer ·Xi Huang,Ley Moy Ng,(unknown),Peiyong Guan,Mun Juinn Chow,(unknown),(unknown),(unknown),Zhimei Li,Jason Yongsheng Chan,Jing Han Hong,Sheng Rong Ng,Tun Kiat Ko,Hong Lee Heng,Hsiangling Teo,Daniela Rhodes,Patrick Tan,Puay Hoon Tan,Donald P. McDonnell,Bin Tean Teh	0
2	The Impact of Circulating Tumor Cell HOXB13 RNA Detection in Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC) Treated with Abiraterone or Enzalutamide 2024 ·Clinical Cancer Research ·Susan Halabi,(unknown),Joseph J. Park,David M. Nanus,Daniel J. George,Emmanuel S. Antonarakis,Daniel C. Danila,Russell Z. Szmulewitz,Donald P. McDonnell,John D. Norris,Changxue Lu,Jun Luo,Andrew J. Armstrong	8
3	A New Chemotype of Chemically Tractable Nonsteroidal Estrogens Based on a Thieno[2,3- d ]pyrimidine Core 2022 ·ACS Medicinal Chemistry Letters ·(unknown),John D. Norris,Sandeep Artham,Chad Torrice,(unknown),(unknown),Sean W. Fanning,Donald P. McDonnell,Timothy M. Willson	2
4	The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand-activated WT Receptor 2020 ·Molecular Cancer Therapeutics ·(unknown),(unknown),Sunghee Park,Rachid Safi,Sandeep Artham,Steffi Oesterreich,Rinath Jeselsohn,Myles Brown,Sarah Sammons,Suzanne E. Wardell,Ching‐yi Chang,John D. Norris,Donald P. McDonnell	27
5	Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy 2019 ·Breast Cancer Research and Treatment ·Suzanne E. Wardell,(unknown),Christina Chao,(unknown),(unknown),(unknown),(unknown),Jeremy T. Blitzer,John D. Norris,Donald P. McDonnell	25
6	CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer 2017 ·Cancer Research ·Mahmoud A. Alfaqih,Erik R. Nelson,Wen Liu,Rachid Safi,(unknown),Everardo Macias,Joseph Geradts,J. Will Thompson,Laura G. Dubois,Michael R. Freeman,Ching‐yi Chang,Jen‐Tsan Chi,Donald P. McDonnell,Stephen J. Freedland	89
7	CDK4/6 Therapeutic Intervention and Viable Alternative to Taxanes in CRPC 2017 ·Molecular Cancer Research ·James P. Stice,Suzanne E. Wardell,John D. Norris,(unknown),Holly M. Alley,(unknown),(unknown),Rachid Safi,Peter Winter,(unknown),Rigel J. Kishton,Scott A. Lawrence,Jay C. Strum,Donald P. McDonnell	22
8	Efficacy of SERD/SERM Hybrid-CDK4/6 Inhibitor Combinations in Models of Endocrine Therapy–Resistant Breast Cancer 2015 ·Clinical Cancer Research ·Suzanne E. Wardell,Matthew J. Ellis,Holly M. Alley,(unknown),Todd VanArsdale,Stephen G. Dann,Kim Arndt,Tina Primeau,Elizabeth Griffin,Jieya Shao,Robert G. Crowder,Jinping Lai,John D. Norris,Donald P. McDonnell,Shunqiang Li	115
9	Delineation of a FOXA1/ERα/AGR2 Regulatory Loop That Is Dysregulated in Endocrine Therapy–Resistant Breast Cancer 2014 ·Molecular Cancer Research ·Tricia M. Wright,Suzanne E. Wardell,Jeff S. Jasper,James P. Stice,Rachid Safi,Erik R. Nelson,Donald P. McDonnell	33
10	Bazedoxifene Exhibits Antiestrogenic Activity in Animal Models of Tamoxifen-Resistant Breast Cancer: Implications for Treatment of Advanced Disease 2013 ·Clinical Cancer Research ·Suzanne E. Wardell,Erik R. Nelson,Christina Chao,Donald P. McDonnell	113
11	27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiologybreakdown → 2013 ·Science ·Erik R. Nelson,Suzanne E. Wardell,Jeff S. Jasper,Sung Hee Park,Sunil Suchindran,Matthew K. Howe,(unknown),(unknown),Patrick M. Sullivan,Varun Sondhi,Michihisa Umetani,Joseph Geradts,Donald P. McDonnell	632
12	Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation 2011 ·Proceedings of the National Academy of Sciences ·Ryan D. Michalek,Valerie A. Gerriets,Amanda Nichols,Makoto Inoue,Dmitri Kazmin,Ching‐yi Chang,Mary A. Dwyer,Erik R. Nelson,Kristen Pollizzi,Olga Ilkayeva,Vincent Giguère,William J. Zuercher,Jonathan D. Powell,Mari L. Shinohara,Donald P. McDonnell,Jeffrey C. Rathmell	169
13	CaM Kinase Kinase β-Mediated Activation of the Growth Regulatory Kinase AMPK Is Required for Androgen-Dependent Migration of Prostate Cancer Cells 2010 ·Cancer Research ·Daniel E. Frigo,Matthew K. Howe,Bryan M. Wittmann,(unknown),Ian Cushman,Qianben Wang,Myles Brown,Anthony R. Means,Donald P. McDonnell	107
14	WNT11 Expression Is Induced by Estrogen-Related Receptor α and β-Catenin and Acts in an Autocrine Manner to Increase Cancer Cell Migration 2010 ·Cancer Research ·Mary A. Dwyer,James D. Joseph,(unknown),Matthew L. Eaton,Rebecca Kunder,Dmitri Kazmin,Ching‐yi Chang,Donald P. McDonnell	121
15	Estrogen-Related Receptor α Is Critical for the Growth of Estrogen Receptor–Negative Breast Cancer 2008 ·Cancer Research ·Rebecca A. Stein,Ching‐yi Chang,Dmitri Kazmin,James M. Way,Thies Schroeder,Melanie Wergin,Mark W. Dewhirst,Donald P. McDonnell	132
16	Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic 2008 ·Cancer Research ·Andrea B. Sherk,Daniel E. Frigo,Christine G. Schnackenberg,Jeffrey D. Bray,Nicholas J. Laping,Walter Trizna,Marlys Hammond,Jaclyn R. Patterson,Scott K. Thompson,Dmitri Kazmin,John D. Norris,Donald P. McDonnell	174
17	Characterization of Antiestrogenic Activity of the Chinese Herb, Prunella vulgaris , Using In Vitro and In Vivo (Mouse Xenograft) Models1 2008 ·Biology of Reproduction ·Nancy Collins,Elizabeth C. Lessey,Carolyn D. DuSell,Donald P. McDonnell,(unknown),Wilder A. Palomino,M. Illera,Xianzhong Yu,(unknown),(unknown),Bruce A. Lessey	40
18	The Molecular Mechanisms Underlying the Proinflammatory Actions of Thiazolidinediones in Human Macrophages 2007 ·Molecular Endocrinology ·Julie M. Hall,Donald P. McDonnell	32
19	Ligand-Selective Interactions of ER Detected in Living Cells by Fluorescence Resonance Energy Transfer 2002 ·Molecular Endocrinology ·Ross Weatherman,Ching‐yi Chang,Nicola J. Clegg,D. C. Carroll,Richard N. Day,John D. Baxter,Donald P. McDonnell,Thomas S. Scanlan,Fred Schaufele	46
20	The Estrogen Receptor β-Isoform (ERβ) of the Human Estrogen Receptor Modulates ERα Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens1breakdown → 1999 ·Endocrinology ·Julie M. Hall,Donald P. McDonnell	866

About Donald P. McDonnell

Donald P. McDonnell is a scholar working on Genetics, Toxicology and Cancer Research, having authored 272 papers that have together received 23.8k indexed citations. Recurring topics across this work include Estrogen and related hormone effects (161 papers), Retinoids in leukemia and cellular processes (38 papers) and Prostate Cancer Treatment and Research (24 papers). The work is most often cited by research in Genetics (11.5k citations), Cancer Research (3.5k citations) and Endocrinology, Diabetes and Metabolism (3.0k citations). Donald P. McDonnell has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include John D. Norris, Julie M. Hall, Ching‐yi Chang, Suzanne E. Wardell, Kevin W. Gaido, Erik R. Nelson, Rachid Safi, Mark E. Goldman, Dmitri Kazmin and Bert W. O’Malley. Their work appears in journals such as Science, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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