Mark W. Dewhirst

61.0k citations

627 papers · 48.6k indexed · 13 hit papers · h-index 105

Molecular Biology top 0.1%
Biomedical Engineering top 0.02%
Cancer Research top 0.01%
Radiology, Nuclear Medicine and Imaging top 0.02%
Oncology top 0.1%

Co-authors: Benjamin J. Moeller David M. Brizel Timothy W. Secomb Rod D. Braun Yiting Cao David Needham Garheng Kong Jeremy N. Rich
Topics: Cancer, Hypoxia, and Metabolism (169 papers)Ultrasound and Hyperthermia Applications (129 papers)Angiogenesis and VEGF in Cancer (70 papers)
Cited by: Cancer Research Biomaterials Radiology, Nuclear Medicine and Imaging
Journals: Nature Proceedings of the National Academy of Sciences Journal of Clinical Investigation
Partner nations: United States Canada Germany

In The Last Decade

Mark W. Dewhirst

614 papers receiving 47.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

2006 4.8k citations Mark W. Dewhirst, Jeremy N. Rich et al. profile →
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

2008 1.3k citations Pierre Sonveaux, Thies Schroeder et al. profile →
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma.

1996 1.0k citations Mark W. Dewhirst et al. profile →
A dual-emissive-materials design concept enables tumour hypoxia imaging

2009 1.0k citations Mark W. Dewhirst et al. profile →
Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

1997 896 citations Mark W. Dewhirst et al. profile →
Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors

2004 831 citations Yiting Cao, Mark W. Dewhirst et al. profile →
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response

2008 798 citations Mark W. Dewhirst, Yiting Cao et al. profile →
Tumor Vascular Permeability, Accumulation, and Penetration of Macromolecular Drug Carriers

2006 743 citations Matthew R. Dreher, Wenge Liu et al. profile →
Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia

2003 732 citations Mark W. Dewhirst, Benjamin L. Viglianti et al. profile →
A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model.

2000 627 citations David Needham, Mark W. Dewhirst et al. profile →
Transport of drugs from blood vessels to tumour tissue

2017 571 citations Mark W. Dewhirst et al. profile →
Thresholds for thermal damage to normal tissues: An update

2011 563 citations Chelsea D. Landon, Ashley A. Manzoor et al. profile →
Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size.

2000 525 citations Mark W. Dewhirst et al. profile →

Peers

Countries citing papers authored by Mark W. Dewhirst

Since Specialization

Citations

This map shows the geographic impact of Mark W. Dewhirst's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark W. Dewhirst with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark W. Dewhirst more than expected).

Fields of papers citing papers by Mark W. Dewhirst

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark W. Dewhirst. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark W. Dewhirst. The network helps show where Mark W. Dewhirst may publish in the future.

Co-authorship network of co-authors of Mark W. Dewhirst

This figure shows the co-authorship network connecting the top 25 collaborators of Mark W. Dewhirst. A scholar is included among the top collaborators of Mark W. Dewhirst based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark W. Dewhirst. Mark W. Dewhirst is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Long-term Consequences of Pelvic Irradiation: Toxicities, Challenges, and Therapeutic Opportunities with Pharmacologic Mitigators 2020 ·Clinical Cancer Research ·Jung Wook Huh,Jarred Tanksley,Junzo Chino,Christopher G. Willett,Mark W. Dewhirst	21
2	Distinct Angiogenic Changes during Carcinogenesis Defined by Novel Label-Free Dark-Field Imaging in a Hamster Cheek Pouch Model 2017 ·Cancer Research ·(unknown),(unknown),(unknown),Jeffrey I. Everitt,Alaattin Erkanli,Walter T. Lee,Mark W. Dewhirst,Nirmala Ramanujam	6
3	Improving the Predictive Value of Preclinical Studies in Support of Radiotherapy Clinical Trials 2016 ·Clinical Cancer Research ·C. Norman Coleman,Geoff S. Higgins,J. Martin Brown,Michaël Baumann,David G. Kirsch,Henning Willers,Pataje G.S. Prasanna,Mark W. Dewhirst,Eric J. Bernhard,Mansoor M. Ahmed	59
4	Efficacy and Mechanisms of Aerobic Exercise on Cancer Initiation, Progression, and Metastasis: A Critical Systematic Review of In Vivo Preclinical Data 2016 ·Cancer Research ·Kathleen A. Ashcraft,Ralph M. Peace,Allison Betof Warner,Mark W. Dewhirst,Lee W. Jones	148
5	Radioprotection of the Brain White Matter by Mn(III) N -Butoxyethylpyridylporphyrin–Based Superoxide Dismutase Mimic MnTnBuOE-2-PyP5+ 2014 ·Molecular Cancer Therapeutics ·Douglas H. Weitzel,Artak Tovmasyan,Kathleen A. Ashcraft,Zrinka Rajić,Tin Weitner,Chunlei Liu,Wei Li,Anne F. Buckley,(unknown),Kenneth H. Young,Ramona M. Rodriguiz,William C. Wetsel,Katherine B. Peters,Ivan Spasojević,James E. Herndon,Ines Batinić‐Haberle,Mark W. Dewhirst	57
6	Tumor Cells Upregulate Normoxic HIF-1α in Response to Doxorubicin 2013 ·Cancer Research ·Yiting Cao,(unknown),(unknown),Hong Yuan,Douglas H. Weitzel,Chelsea D. Landon,(unknown),Gabi Hanna,Jeremy N. Rich,James M. Provenzale,Mark W. Dewhirst	90
7	Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors 2012 ·Cancer Research ·Ashley A. Manzoor,Lars H. Lindner,Chelsea D. Landon,Ji Young Park,Andrew J. Simnick,Matthew R. Dreher,Shiva K. Das,Gabi Hanna,Won Park,Ashutosh Chilkoti,Gerben A. Koning,Timo L.M. ten Hagen,David Needham,Mark W. Dewhirst	375
8	Bevacizumab-Induced Alterations in Vascular Permeability and Drug Delivery: A Novel Approach to Augment Regional Chemotherapy for In-Transit Melanoma 2012 ·Clinical Cancer Research ·Ryan S. Turley,Andrew N. Fontanella,James C. Padussis,(unknown),Yoshihiro Tokuhisa,Eugenia H. Cho,Gabi Hanna,Georgia M. Beasley,Christina K. Augustine,Mark W. Dewhirst,Douglas S. Tyler	48
9	Comparison of Genomics and Functional Imaging from Canine Sarcomas Treated with Thermoradiotherapy Predicts Therapeutic Response and Identifies Combination Therapeutics 2011 ·Clinical Cancer Research ·Jen‐Tsan Chi,Donald Ε. Thrall,J Chen,Stacey A. Snyder,Diane Fels,Chelsea D. Landon,Linda McCall,Lan Lan,Marlene Hauck,James R. MacFall,Benjamin L. Viglianti,Mark W. Dewhirst	27
10	Effect of Low-Fat Diets on Plasma Levels of NF-κB–Regulated Inflammatory Cytokines and Angiogenic Factors in Men with Prostate Cancer 2011 ·Cancer Prevention Research ·John V. Heymach,Terry J. Shackleford,Hai T. Tran,Suk-Young Yoo,Kim‐Anh Do,Melanie Wergin,Pierre Saintigny,Robin T. Vollmer,Thomas J. Polascik,Denise C. Snyder,Mack T. Ruffin,Shaoyu Yan,Mark W. Dewhirst,Ajaikumar B. Kunnumakkara,Bharat B. Aggarwal,Wendy Demark‐Wahnefried	43
11	Dynamic Contrast-enhanced Magnetic Resonance Imaging as a Predictor of Clinical Outcome in Canine Spontaneous Soft Tissue Sarcomas Treated with Thermoradiotherapy 2009 ·Clinical Cancer Research ·Benjamin L. Viglianti,Michaël Lora‐Michiels,(unknown),Lan Lan,(unknown),Linda Sanders,Oana Craciunescu,Željko Vujašković,Donald Ε. Thrall,James R. MacFall,Cecil Charles,Terence Z. Wong,Mark W. Dewhirst	33
12	The Pervasive Presence of Fluctuating Oxygenation in Tumors 2008 ·Cancer Research ·Laura I. Cárdenas-Navia,Daniel Mace,Rachel A. Richardson,David F. Wilson,Siqing Shan,Mark W. Dewhirst	137
13	Estrogen-Related Receptor α Is Critical for the Growth of Estrogen Receptor–Negative Breast Cancer 2008 ·Cancer Research ·Rebecca A. Stein,Ching‐yi Chang,Dmitri Kazmin,James M. Way,Thies Schroeder,Melanie Wergin,Mark W. Dewhirst,Donald P. McDonnell	132
14	Thermal Cycling Enhances the Accumulation of a Temperature-Sensitive Biopolymer in Solid Tumors 2007 ·Cancer Research ·Matthew R. Dreher,Wenge Liu,Charles R. Michelich,Mark W. Dewhirst,Ashutosh Chilkoti	123
15	Systemic Overexpression of Angiopoietin-2 Promotes Tumor Microvessel Regression and Inhibits Angiogenesis and Tumor Growth 2007 ·Cancer Research ·Yiting Cao,Pierre Sonveaux,Shanling Liu,Yulin Zhao,Jing Mi,Bryan M. Clary,Chuan‐Yuan Li,Christopher D. Kontos,Mark W. Dewhirst	78
16	Gene Expression Profiles of Multiple Breast Cancer Phenotypes and Response to Neoadjuvant Chemotherapy 2006 ·Clinical Cancer Research ·Holly K. Dressman,Christopher Hans,Andrea H. Bild,John A. Olson,Eric L. Rosen,P. Kelly Marcom,Vlayka Liotcheva,Ellen L. Jones,Željko Vujašković,Jeffrey R. Marks,Mark W. Dewhirst,Mike West,Joseph R. Nevins,Kimberly Blackwell	121
17	Tumor Necrosis Factor-α Is a Potent Endogenous Mutagen that Promotes Cellular Transformation 2006 ·Cancer Research ·Bin Yan,Huili Wang,Zahid N. Rabbani,Yulin Zhao,Wenrong Li,Yuqing Yuan,Fang Li,Mark W. Dewhirst,Chuan‐Yuan Li	131
18	Development of Magnetic Resonance Imaging Contrast Material for In vivo Mapping of Tissue Transglutaminase Activity 2005 ·Cancer Research ·(unknown),Tevie Mehlman,Thung‐S. Lai,Charles S. Greenberg,Mark W. Dewhirst,Michal Neeman	25
19	Electrophoretic Evaluation of Sera from Dogs with Cancer 1978 ·American Journal of Veterinary Research ·(unknown),Mark W. Dewhirst,Edward L. Gillette,(unknown)	2
20	Idiopathic Monoclonal (IgA) Gammopathy in a Dog 1977 ·Journal of the American Veterinary Medical Association ·Mark W. Dewhirst,Gordon Stamp,Arthur I. Hurvitz	3

About Mark W. Dewhirst

Mark W. Dewhirst is a scholar working on Cancer Research, Radiology, Nuclear Medicine and Imaging and Biophysics, having authored 627 papers that have together received 48.6k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (169 papers), Ultrasound and Hyperthermia Applications (129 papers) and Angiogenesis and VEGF in Cancer (70 papers). The work is most often cited by research in Cancer Research (13.7k citations), Biomaterials (5.9k citations) and Radiology, Nuclear Medicine and Imaging (8.9k citations). Mark W. Dewhirst has collaborated with scholars based in United States, Canada and Germany. Frequent co-authors include Benjamin J. Moeller, David M. Brizel, Timothy W. Secomb, Rod D. Braun, Yiting Cao, David Needham, Garheng Kong, Jeremy N. Rich, Darell D. Bigner and Roger E. McLendon. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact