Jack U. Flanagan

7.9k total citations · 1 hit paper
85 papers, 5.8k citations indexed

About

Jack U. Flanagan is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Jack U. Flanagan has authored 85 papers receiving a total of 5.8k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Molecular Biology, 15 papers in Oncology and 10 papers in Genetics. Recurrent topics in Jack U. Flanagan's work include PI3K/AKT/mTOR signaling in cancer (17 papers), Genomics, phytochemicals, and oxidative stress (13 papers) and Glutathione Transferases and Polymorphisms (12 papers). Jack U. Flanagan is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (17 papers), Genomics, phytochemicals, and oxidative stress (13 papers) and Glutathione Transferases and Polymorphisms (12 papers). Jack U. Flanagan collaborates with scholars based in New Zealand, Australia and United Kingdom. Jack U. Flanagan's co-authors include John D. Hayes, Ian R. Jowsey, William A. Denny, Michael P. Hay, Peter R. Shepherd, C. Roland Wolf, Mark J. I. Paine, Michael J. Sutcliffe, Gordon C. K. Roberts and Denise A. Chan and has published in prestigious journals such as Journal of Biological Chemistry, PLoS ONE and Journal of Molecular Biology.

In The Last Decade

Jack U. Flanagan

84 papers receiving 5.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

GLUTATHIONE TRANSFERASES

2004 2.9k citations John D. Hayes, Jack U. Flanagan et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jack U. Flanagan New Zealand	31	3.8k	620	596	593	440	85	5.8k
Masami Suganuma Japan	58	3.8k 1.0×	371 0.6×	856 1.4×	1.1k 1.8×	571 1.3×	201	10.0k
Kimihiko Satoh Japan	31	5.5k 1.4×	757 1.2×	737 1.2×	634 1.1×	404 0.9×	105	7.3k
Aglaia Pappa Greece	46	3.3k 0.9×	282 0.5×	849 1.4×	640 1.1×	269 0.6×	133	6.8k
Edmund Maser Germany	44	2.7k 0.7×	1.0k 1.6×	320 0.5×	417 0.7×	231 0.5×	194	6.0k
Dai Nakae Japan	36	1.9k 0.5×	487 0.8×	859 1.4×	642 1.1×	258 0.6×	188	5.0k
Young‐Nam Cha South Korea	38	2.5k 0.7×	675 1.1×	408 0.7×	409 0.7×	280 0.6×	100	4.6k
Bao Ting Zhu United States	38	2.6k 0.7×	850 1.4×	634 1.1×	836 1.4×	339 0.8×	160	6.6k
Cecil B. Pickett United States	25	6.0k 1.6×	486 0.8×	496 0.8×	597 1.0×	550 1.3×	46	7.8k
Brian Coles United States	36	2.6k 0.7×	487 0.8×	648 1.1×	451 0.8×	269 0.6×	65	4.2k
Ichiro Hatayama Japan	22	4.2k 1.1×	460 0.7×	430 0.7×	355 0.6×	338 0.8×	61	5.3k

Countries citing papers authored by Jack U. Flanagan

Since Specialization

Citations

This map shows the geographic impact of Jack U. Flanagan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jack U. Flanagan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jack U. Flanagan more than expected).

Fields of papers citing papers by Jack U. Flanagan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jack U. Flanagan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jack U. Flanagan. The network helps show where Jack U. Flanagan may publish in the future.

Co-authorship network of co-authors of Jack U. Flanagan

This figure shows the co-authorship network connecting the top 25 collaborators of Jack U. Flanagan. A scholar is included among the top collaborators of Jack U. Flanagan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jack U. Flanagan. Jack U. Flanagan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Masson, Glenn R., Woo Jung Lee, James M. Dickson, et al.. (2024). ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding. Biochemical Journal. 481(23). 1787–1802. 1 indexed citations

Teesdale‐Spittle, Paul, et al.. (2024). A Structure‐Activity Investigation of the Fungal Metabolite (−)‐TAN‐2483B: Inhibition of Bruton's Tyrosine Kinase. Chemistry - A European Journal. 30(35). e202401051–e202401051. 1 indexed citations

Lu, Man, Jack U. Flanagan, Ries J. Langley, Michael P. Hay, & Jo K. Perry. (2019). Targeting growth hormone function: strategies and therapeutic applications. Signal Transduction and Targeted Therapy. 4(1). 59–68. 103 indexed citations

Wang, Ke, Yan Zhou, Yi Chen, et al.. (2018). Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds. Acta Pharmacologica Sinica. 39(12). 1902–1912. 11 indexed citations

Azimi, Iman, Jack U. Flanagan, Ralph J. Stevenson, et al.. (2016). Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay. Bioorganic & Medicinal Chemistry. 25(1). 440–449. 16 indexed citations

Marshall, Andrew J., Claire L. Lill, Sharada Kolekar, et al.. (2015). Exploring the isoform selectivity of TGX-221 related pyrido[1,2-a]pyrimidinone-based Class IA PI 3-kinase inhibitors: Synthesis, biological evaluation and molecular modelling. Bioorganic & Medicinal Chemistry. 23(13). 3796–3808. 13 indexed citations

Flanagan, Jack U., Taryn N. Green, Euphemia Leung, et al.. (2014). Evidence That GRIN2A Mutations in Melanoma Correlate with Decreased Survival. Frontiers in Oncology. 3. 333–333. 22 indexed citations

Yosaatmadja, Y., et al.. (2012). Structure of AKR1C3 with 3-phenoxybenzoic acid bound. Acta Crystallographica Section F Structural Biology and Crystallization Communications. 68(4). 409–413. 10 indexed citations

Chan, Denise A., Patrick D. Sutphin, Phuong Nguyen, et al.. (2011). Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality. Science Translational Medicine. 3(94). 94ra70–94ra70. 456 indexed citations

10.

Kendall, Jackie D., Kit Yee Tsang, Raphaël Frédérick, et al.. (2011). Novel pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR. Bioorganic & Medicinal Chemistry. 20(1). 58–68. 30 indexed citations

11.

Archbold, Julia K., Jack U. Flanagan, Harriet A. Watkins, Joseph J. Gingell, & Debbie L. Hay. (2011). Structural insights into RAMP modification of secretin family G protein-coupled receptors: implications for drug development. Trends in Pharmacological Sciences. 32(10). 591–600. 67 indexed citations

12.

Bonnet, Muriel, Jack U. Flanagan, Denise A. Chan, et al.. (2011). SAR studies of 4-pyridyl heterocyclic anilines that selectively induce autophagic cell death in von Hippel-Lindau-deficient renal cell carcinoma cells. Bioorganic & Medicinal Chemistry. 19(11). 3347–3356. 19 indexed citations

13.

Flanagan, Jack U. & Mark L. Smythe. (2011). Sigma-class glutathione transferases. Drug Metabolism Reviews. 43(2). 194–214. 43 indexed citations

14.

Oakley, Aaron J., Angelika N. Christ, Alan G. Clark, et al.. (2009). Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D 2 synthase. European Journal of Medicinal Chemistry. 45(2). 447–454. 18 indexed citations

15.

Hadler, Kieran S., Thomas Huber, A. Ian Cassady, et al.. (2008). Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases?. BMC Research Notes. 1(1). 78–78. 10 indexed citations

16.

Aagaard, Anna, Pawel Listwan, Nathan Cowieson, et al.. (2005). An Inflammatory Role for the Mammalian Carboxypeptidase Inhibitor Latexin: Relationship to Cystatins and the Tumor Suppressor TIG1. Structure. 13(2). 309–317. 69 indexed citations

17.

Caccuri, Anna Maria, Giovanni Antonini, Philip G. Board, et al.. (2001). Human Glutathione Transferase T2-2 Discloses Some Evolutionary Strategies for Optimization of the Catalytic Activity of Glutathione Transferases. Journal of Biological Chemistry. 276(8). 5432–5437. 11 indexed citations

18.

Jowsey, Ian R., Anne M. Thomson, Jack U. Flanagan, et al.. (2001). Mammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthases. Biochemical Journal. 359(3). 507–507. 78 indexed citations

19.

Flanagan, Jack U., Wayne A. King, Michael W. Parker, Philip G. Board, & Gareth Chelvanayagam. (2000). Ab initio calculations on hidden modulators of theta class glutathione transferase activity. Proteins Structure Function and Bioinformatics. 39(3). 235–243. 3 indexed citations

20.

Flanagan, Jack U., Jamie Rossjohn, Michael W. Parker, Philip G. Board, & Gareth Chelvanayagam. (1998). A homology model for the human theta-class glutathione transferase T1–1. Proteins Structure Function and Bioinformatics. 33(3). 444–454. 15 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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