Jason Halladay

2.3k citations
42 papers · 769 · h-index 16

Impact in

  • Pharmacology top 1%
    • Pharmacogenetics and Drug Metabolism
    • Drug-Induced Hepatotoxicity and Protection
  • Oncology top 10%
    • Drug Transport and Resistance Mechanisms

Papers in

  • Pharmacology 25
    • Pharmacogenetics and Drug Metabolism 22
    • Drug-Induced Hepatotoxicity and Protection 6
  • Molecular Biology 17
    • Protein Degradation and Inhibitors 5
    • PI3K/AKT/mTOR signaling in cancer 4
    • Cancer therapeutics and mechanisms 3
Co-authors
S. Cyrus Khojasteh (17 shared papers)Jane R. Kenny (8 shared papers)Cornelis E. C. A. Hop (11 shared papers)Susan Wong (11 shared papers)Anthony Y.H. Lu (1 shared paper)Saileta Prabhu (1 shared paper)Jasleen K. Sodhi (9 shared papers)Patrick Poulin (2 shared papers)
Journals
Drug Metabolism and Disposition (8 papers)Journal of Pharmaceutical Sciences (4 papers)Blood (3 papers)Molecular Cancer Therapeutics (2 papers)Xenobiotica (2 papers)
Partner nations
United StatesFranceNorway

In The Last Decade

Jason Halladay

41 papers receiving 713 citations

Peers

Jason Halladay
Comparison fields: 5 of 93
  • Pharmacology 344
  • Oncology 255
  • Computational Theory and Mathematics 112
  • Biochemistry 45
  • Molecular Biology 328
Replace Jairam Palamanda with:
Jairam Palamanda United States
Stephen Fowler Switzerland
Ken Grime United Kingdom
Hugues Dolgos Germany
Vincent Peterkin United States
Rowan Stringer Switzerland
Pranav Shah United States
Satoru Asahi Japan
Cindy Q. Xia United States
Oliver Hatley United Kingdom
Jason Halladay relative to Jairam Palamanda United States Jairam Palamanda's profile →
Citations per field
00.5×1.5×2×2.3×
Jairam Palamanda · 1×
Citations per year

Countries citing papers authored by Jason Halladay

Since Specialization
Citations

This map shows the geographic impact of Jason Halladay's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jason Halladay with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jason Halladay more than expected).

Fields of papers citing papers by Jason Halladay

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jason Halladay. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jason Halladay. The network helps show where Jason Halladay may publish in the future.

Co-authors

The 25 scholars most cited alongside Jason Halladay, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jason Halladay Line = papers co-authored together Jason Halladay links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 42 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity
European Journal of Drug Metabolism and Pharmacokinetics ·S. Cyrus Khojasteh, Saileta Prabhu, Jane R. Kenny, Jason Halladay, Anthony Y.H. Lu
2011116
2
Comparative Assessment of In Vitro–In Vivo Extrapolation Methods used for Predicting Hepatic Metabolic Clearance of Drugs
Journal of Pharmaceutical Sciences ·Patrick Poulin, Cornelis E. C. A. Hop, Quynh Ho, Jason Halladay, Sami Haddad, Jane R. Kenny
201257
3
A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
Drug Metabolism and Disposition ·Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John Barr, Jeffrey P. Jones, Jason Halladay
201549
4
Preclinical assessment of the absorption, distribution, metabolism and excretion of GDC-0449 (2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide), an orally bioavailable systemic Hedgehog signalling pathway inhibitor
Xenobiotica ·Harvey Wong, J.Z. Chen, Bilin Chou, Jason Halladay, Jane R. Kenny, Hanson La, James C. Marsters, Emile G. Plise, Patrick J. Rudewicz, Kirk Robarge, Young G. Shin, Susan Wong, Chen Zhang, S. Cyrus Khojasteh
200947
5
Learning and Confirming with Preclinical Studies: Modeling and Simulation in the Discovery of GDC-0917, an Inhibitor of Apoptosis Proteins Antagonist
Drug Metabolism and Disposition ·Harvey Wong, Stephen E. Gould, Nageshwar Budha, Walter C. Darbonne, Edward E. Kadel, Hank La, Bruno Alicke, Jason Halladay, Rebecca J. Erickson, Chia C. Portera, Anthony W. Tolcher, J. Infante, Michael Mamounas, John A. Flygare, Cornelis E. C. A. Hop, Wayne J. Fairbrother
201342
6
Discovery of an orally active benzoxaborole prodrug effective in the treatment of Chagas disease in non-human primates
Nature Microbiology ·Ángel M. Padilla, Wei Wang, Tsutomu Akama, David S. Carter, Eric E. Easom, Yvonne R. Freund, Jason Halladay, Yang Liu, Sarah A. Hamer, Carolyn L. Hodo, Gregory K. Wilkerson, Dylan Orr, Brooke E. White, Arlene J. George, Huifeng Shen, Yiru Jin, Michael Zhuo Wang, Susanna Tse, Robert T. Jacobs, Rick L. Tarleton
202239
7
Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans
Drug Metabolism and Disposition ·Ryan Takahashi, Edna F. Choo, Shu‐Chang Ma, S. Wong, Jason Halladay, Yuzhong Deng, Isabelle Rooney, Mary Gates, Cornelis E. C. A. Hop, S. Cyrus Khojasteh, Mark J. Dresser, Luna Musib
201537
8
Association of CYP2C9*2 With Bosentan-Induced Liver Injury
Clinical Pharmacology & Therapeutics ·Svetlana Markova, Teresa De Marco, Nasrine Bendjilali, E. Kobashigawa, Joel Mefford, Jasleen K. Sodhi, H. Le, Chang Zhi Zhang, Jason Halladay, Allan E. Rettie, S. Cyrus Khojasteh, Dana McGlothlin, Alan H.B. Wu, W.C. Hsueh, John S. Witte, Janice B. Schwartz, Deanna L. Kroetz
201336
9
An ‘all-inclusive’ 96-well cytochrome P450 induction method: Measuring enzyme activity, mRNA levels, protein levels, and cytotoxicity from one well using cryopreserved human hepatocytes
Journal of Pharmacological and Toxicological Methods ·Jason Halladay, Susan Wong, S. Cyrus Khojasteh, Susan Grepper
201227
10
Combination Drug Scheduling Defines a “Window of Opportunity” for Chemopotentiation of Gemcitabine by an Orally Bioavailable, Selective ChK1 Inhibitor, GNE-900
Molecular Cancer Therapeutics ·Elizabeth Blackwood, Jennifer Epler, Ivana Yen, Michael Flagella, Thomas O’Brien, Marie Evangelista, Stephen Schmidt, Xiaohai Yang, Jonathan Choi, Kaska Kowanetz, Judi Ramiscal, Kenton Wong, Diana Jakubiak, Sharon Yee, Gary Cain, Lewis Gazzard, Karen Williams, Jason Halladay, Peter K. Jackson, Shiva Malek
201322
11
Preclinical pharmacokinetics of the novel PI3K inhibitor GDC-0941 and prediction of its pharmacokinetics and efficacy in human
Xenobiotica ·Laurent Salphati, Jodie Pang, Emile G. Plise, Bilin Chou, Jason Halladay, Alan G. Olivero, Patrick J. Rudewicz, Qingping Tian, Susan Wong, Xiaolin Zhang
201120
12
Metabolic Stability Screen for Drug Discovery Using Cassette Analysis and Column Switching
Drug Metabolism Letters ·Jason Halladay, Susan Wong, Sharmin Jaffer, Achintya Sinhababu, S. Cyrus Khojasteh-Bakht
200720
13
Going Beyond Common Drug Metabolizing Enzymes: Case Studies of Biotransformation Involving Aldehyde Oxidase, γ-Glutamyl Transpeptidase, Cathepsin B, Flavin-Containing Monooxygenase, and ADP-Ribosyltransferase
Drug Metabolism and Disposition ·Peter W. Fan, Dawei Zhang, Jason Halladay, James P. Driscoll, S. Cyrus Khojasteh
201619
14
On the prediction of hepatic clearance using the diluted plasma in metabolic stability assay
Journal of Pharmaceutical Sciences ·Leonid M. Berezhkovskiy, S. Cyrus Khojasteh, Jason Halladay, Cornelis E. C. A. Hop
200818
15
Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications
Drug Metabolism Reviews ·Kevin A. Ford, Gregory Ryslik, Jasleen K. Sodhi, Jason Halladay, Dolo Diaz, Donna M. Dambach, Melisa Masuda
201515
16
Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1
Bioorganic & Medicinal Chemistry Letters ·Lewis Gazzard, B.A. Appleton, Kerry L. Chapman, Huifen Chen, Kevin Clark, Joy Drobnick, Simon Goodacre, Jason Halladay, Joseph P. Lyssikatos, Stephen Schmidt, Steve Sideris, Christian Wiesmann, Karen Williams, Wu Ping, Ivana Yen, Shiva Malek
201415
17
Comparative Pharmacokinetic and Disposition Studies of [1-14C]1-Eicosanylcyclohexane, a Surrogate Mineral Hydrocarbon, in Female Fischer-344 and Sprague-Dawley Rats
Drug Metabolism and Disposition ·Jason Halladay, Carl R. Mackerer, Lorraine E. Twerdok, I.G. Sipes
200214
18
High-Throughput, 384-Well, LC-MS/MS CYP Inhibition Assay Using Automation, Cassette-Analysis Technique and Streamlined Data Analysis
Drug Metabolism Letters ·Jason Halladay, Erlie Delarosa, Daniel Tran, Leslie Wang, Susan Wong, S. Cyrus Khojasteh
201114
19
Evaluation of Time-Dependent Cytochrome P450 Inhibition in a High-Throughput, Automated Assay: Introducing a Novel Area Under the Curve Shift Approach
Drug Metabolism Letters ·Sophie Mukadam, Suzanne Tay, Daniel Tran, Leslie Wang, Erlie Delarosa, S. Cyrus Khojasteh, Jason Halladay, Jane R. Kenny
201213
20
1-Aminobenzotriazole Coincubated with (S)-Warfarin Results in Potent Inactivation of CYP2C9
Drug Metabolism and Disposition ·Jasleen K. Sodhi, Kevin A. Ford, Sophie Mukadam, Susan Wong, Cornelis E. C. A. Hop, S. Cyrus Khojasteh, Jason Halladay
201412

About Jason Halladay

Jason Halladay is a scholar working on Pharmacology, Molecular Biology, Oncology, Computational Theory and Mathematics and Hematology, having authored 42 papers that have together received 769 indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (22 papers), Drug Transport and Resistance Mechanisms (12 papers), Computational Drug Discovery Methods (7 papers), Drug-Induced Hepatotoxicity and Protection (6 papers), Protein Degradation and Inhibitors (5 papers), PI3K/AKT/mTOR signaling in cancer (4 papers), Multiple Myeloma Research and Treatments (4 papers) and Cancer therapeutics and mechanisms (3 papers). The work is most often cited by research in Pharmacology (344 citations), Oncology (255 citations), Computational Theory and Mathematics (112 citations), Biochemistry (45 citations) and Molecular Biology (328 citations). Jason Halladay has collaborated with scholars based in United States, France and Norway. Frequent co-authors include S. Cyrus Khojasteh, Jane R. Kenny, Cornelis E. C. A. Hop, Susan Wong, Anthony Y.H. Lu, Saileta Prabhu, Jasleen K. Sodhi, Patrick Poulin, Sami Haddad and Leonid M. Berezhkovskiy. Their work appears in journals such as Drug Metabolism and Disposition, Journal of Pharmaceutical Sciences, Blood, Molecular Cancer Therapeutics and Xenobiotica.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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