Stephen E. Gould

8.3k total citations · 4 hit papers
48 papers, 5.3k citations indexed

About

Stephen E. Gould is a scholar working on Molecular Biology, Oncology and Pathology and Forensic Medicine. According to data from OpenAlex, Stephen E. Gould has authored 48 papers receiving a total of 5.3k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Molecular Biology, 17 papers in Oncology and 7 papers in Pathology and Forensic Medicine. Recurrent topics in Stephen E. Gould's work include Hedgehog Signaling Pathway Studies (14 papers), Epigenetics and DNA Methylation (7 papers) and Melanoma and MAPK Pathways (6 papers). Stephen E. Gould is often cited by papers focused on Hedgehog Signaling Pathway Studies (14 papers), Epigenetics and DNA Methylation (7 papers) and Melanoma and MAPK Pathways (6 papers). Stephen E. Gould collaborates with scholars based in United States, France and New Zealand. Stephen E. Gould's co-authors include Frédéric J. de Sauvage, Robert L. Yauch, Bruno Alicke, Thomas Januario, Jennifer A. Low, Christopher A. Callahan, Tracy Tang, Lee L. Rubin, Charles M. Rudin and Jeremy Stinson and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Stephen E. Gould

46 papers receiving 5.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A paracrine requirement for hedgehog signalling in cancer

2008 770 citations Robert L. Yauch, Stephen E. Gould et al. Nature profile →
Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

2009 761 citations Charles M. Rudin, Christine L. Hann et al. New England Journal of Medicine profile →
Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

2009 670 citations Robert L. Yauch, Gerrit J.P. Dijkgraaf et al. Science profile →
MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade

2016 527 citations Peter Ebert, Jeanne Cheung et al. Immunity profile →

Peers

Countries citing papers authored by Stephen E. Gould

Since Specialization

Citations

This map shows the geographic impact of Stephen E. Gould's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen E. Gould with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen E. Gould more than expected).

Fields of papers citing papers by Stephen E. Gould

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen E. Gould. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen E. Gould. The network helps show where Stephen E. Gould may publish in the future.

Co-authorship network of co-authors of Stephen E. Gould

This figure shows the co-authorship network connecting the top 25 collaborators of Stephen E. Gould. A scholar is included among the top collaborators of Stephen E. Gould based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stephen E. Gould. Stephen E. Gould is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	IAP antagonist GDC-0917 is more potent than Debio1143 in promoting cell death, c-IAP1 degradation and tumor growth inhibition 2022 ·Cell Death and Disease ·Bruno Alicke, Eugene Varfolomeev, (unknown), Alexandra Frommlet, Savita Ubhayakar, John G. Quinn, Wayne J. Fairbrother, Robin L. Jones, Stephen E. Gould, Domagoj Vucic	3
2	Generalized Additive Mixed Modeling of Longitudinal Tumor Growth Reduces Bias and Improves Decision Making in Translational Oncology 2020 ·Cancer Research ·William F. Forrest, Bruno Alicke, Oleg Mayba, Magdalena Osińska, (unknown), Paweł Piątkowski, (unknown), (unknown), Stephen E. Gould	11
3	Immunization associated with primary tumor growth leads to rejection of commonly used syngeneic tumors upon tumor rechallenge 2020 ·Journal for ImmunoTherapy of Cancer ·Bruno Alicke, Klára Tótpál, Jill Schartner, Amy M. Berkley, Sophie M. Lehar, Aude-Hélène Capietto, Rafael Cubas, Stephen E. Gould	15
4	Chemotherapy Combines Effectively with Anti–PD-L1 Treatment and Can Augment Antitumor Responses 2018 ·The Journal of Immunology ·Rafael Cubas, Марина Москаленко, Jeanne Cheung, Michelle Yang, Erin McNamara, Huizhong Xiong, Sabine Hoves, Carola H. Ries, Jeong Kim, Stephen E. Gould	41
5	A cell identity switch allows residual BCC to survive Hedgehog pathway inhibition 2018 ·Nature ·Brian Biehs, Gerrit J.P. Dijkgraaf, Robert Piskol, Bruno Alicke, Soufiane Boumahdi, Franklin Peale, Stephen E. Gould, Frédéric J. de Sauvage	95
6	Carcinogenicity assessment of the Hedgehog pathway inhibitor, vismodegib in Tg.rasH2 mice and Sprague-Dawley rats 2017 ·Regulatory Toxicology and Pharmacology ·Jinze Li, Eric J. Morinello, Thomas Larsen, (unknown), Ivor Caro, Stephen E. Gould, (unknown), (unknown), Noël Dybdal, Donna M. Dambach, Melissa M. Schutten	2
7	MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade breakdown → 2016 ·Immunity ·Peter Ebert, Jeanne Cheung, Yagai Yang, Erin McNamara, Rebecca Hong, Марина Москаленко, Stephen E. Gould, Heather Maecker, Bryan Irving, Jeong Kim, Marcia Belvin, Ira Mellman	527
8	PTEN Loss Mitigates the Response of Medulloblastoma to Hedgehog Pathway Inhibition 2013 ·Cancer Research ·Ciara Metcalfe, Bruno Alicke, Ailey Crow, (unknown), Gerrit J.P. Dijkgraaf, Franklin Peale, Stephen E. Gould, Frédéric J. de Sauvage	44
9	Antitumor Activity of Targeted and Cytotoxic Agents in Murine Subcutaneous Tumor Models Correlates with Clinical Response 2012 ·Clinical Cancer Research ·Harvey Wong, Edna F. Choo, Bruno Alicke, Xiao Ding, Hank La, Erin McNamara, Frank‐Peter Theil, Jay Tibbitts, Lori S. Friedman, Cornelis E. C. A. Hop, Stephen E. Gould	96
10	Dogs Are More Sensitive to Antagonists of Inhibitor of Apoptosis Proteins Than Rats and Humans: A Translational Toxicokinetic/Toxicodynamic Analysis 2012 ·Toxicological Sciences ·Harvey Wong, Nageshwar Budha, Kristina West, Elizabeth Blackwood, Joseph A. Ware, Ron Yu, Walter C. Darbonne, Stephen E. Gould, Ronald W. Steigerwalt, Rebecca J. Erickson, (unknown), Patricia LoRusso, S. Gail Eckhardt, Andrew J. Wagner, Iris T. Chan, Michael Mamounas, John A. Flygare, Wayne J. Fairbrother	13
11	Pharmacokinetic–Pharmacodynamic Analysis of Vismodegib in Preclinical Models of Mutational and Ligand-Dependent Hedgehog Pathway Activation 2011 ·Clinical Cancer Research ·Harvey Wong, Bruno Alicke, Kristina West, Patrícia Pacheco, Hank La, Tom Januario, Robert L. Yauch, Frédéric J. de Sauvage, Stephen E. Gould	96
12	Preclinical assessment of novel BRAF inhibitors: integrating pharmacokinetic-pharmacodynamic modelling in the drug discovery process 2011 ·Xenobiotica ·Edna F. Choo, Bruno Alicke, Jason Boggs, (unknown), Stephen E. Gould, Jonas Grina, Kristina West, (unknown), Yingqing Ran, Joachim Rudolph, Steve Wenglowsky	5
13	Small Molecule Inhibition of GDC-0449 Refractory Smoothened Mutants and Downstream Mechanisms of Drug Resistance 2010 ·Cancer Research ·Gerrit J.P. Dijkgraaf, Bruno Alicke, Lasse Weinmann, Thomas Januario, Kristina West, Zora Modrušan, Dan Burdick, Richard Goldsmith, Kirk Robarge, Dan Sutherlin, Suzie J. Scales, Stephen E. Gould, Robert L. Yauch, Frédéric J. de Sauvage	293
14	Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma breakdown → 2009 ·Science ·Robert L. Yauch, Gerrit J.P. Dijkgraaf, Bruno Alicke, Thomas Januario, Christina P. Ahn, Thomas Holcomb, Kanan Pujara, Jeremy Stinson, Christopher A. Callahan, Tracy Tang, J. Fernando Bazán, Zhengyan Kan, Somasekar Seshagiri, Christine L. Hann, Stephen E. Gould, Jennifer A. Low, Charles M. Rudin, Frédéric J. de Sauvage	670
15	Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449 breakdown → 2009 ·New England Journal of Medicine ·Charles M. Rudin, Christine L. Hann, John Laterra, Robert L. Yauch, Christopher A. Callahan, Ling Fu, Thomas Holcomb, Jeremy Stinson, Stephen E. Gould, Barbara Coleman, Patricia LoRusso, Daniel D. Von Hoff, Frédéric J. de Sauvage, Jennifer A. Low	761
16	X Chromosome-linked Inhibitor of Apoptosis Regulates Cell Death Induction by Proapoptotic Receptor Agonists 2009 ·Journal of Biological Chemistry ·Eugene Varfolomeev, Bruno Alicke, J. Michael Elliott, Kerry Zobel, Kristina West, Harvey Wong, Justin M. Scheer, Avi Ashkenazi, Stephen E. Gould, Wayne J. Fairbrother, Domagoj Vucic	47
17	A paracrine requirement for hedgehog signalling in cancer breakdown → 2008 ·Nature ·Robert L. Yauch, Stephen E. Gould, Suzie J. Scales, Tracy Tang, Hua Tian, Christina P. Ahn, Derek Marshall, Ling Fu, Thomas Januario, Dara Kallop, (unknown), Karen Kotkow, James C. Marsters, Lee L. Rubin, Frédéric J. de Sauvage	770
18	Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1+/−p53−/− mice 2004 ·Cancer Cell ·Justyna T. Romer, Hiromichi Kimura, Susan Magdaleno, Ken Sasai, Christine Fuller, Helen Baines, Michele Connelly, Clinton F. Stewart, Stephen E. Gould, Lee L. Rubin, Tom Curran	389
19	BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells1 2002 ·Kidney International ·Stephen E. Gould, (unknown), Simon S. Jones, Haimanti Dorai	198
20	Cellular contribution of bone graft to fusion 2000 ·Journal of Orthopaedic Research® ·Stephen E. Gould, John M. Rhee, Bobby Tay, Norman Y. Otsuka, David S. Bradford	23

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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