Hank La

2.3k citations

23 papers · 792 · h-index 14

Impact in

Oncology
- Cytokine Signaling Pathways and Interactions
Pharmaceutical Science top 10%
- Drug Solubulity and Delivery Systems

Papers in

Molecular Biology 13
- Cancer therapeutics and mechanisms 4
- Retinoids in leukemia and cellular processes 3
- Protein Kinase Regulation and GTPase Signaling 3
- Hedgehog Signaling Pathway Studies 2
Oncology 11
- Drug Transport and Resistance Mechanisms 5

Co-authors: Harvey Wong (14 shared papers)Stephen E. Gould (4 shared papers)Bruno Alicke (4 shared papers)Xiao Ding (3 shared papers)Robert L. Yauch (2 shared papers)Yuzhong Deng (8 shared papers)Cornelis E. C. A. Hop (4 shared papers)Kristina West (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Clinical Cancer Research (2 papers)Journal of Medicinal Chemistry (2 papers)Drug Metabolism and Disposition (2 papers)Journal of Pharmaceutical Sciences (1 paper)
Partner nations: United States France China

In The Last Decade

Hank La

23 papers receiving 753 citations

Peers

Countries citing papers authored by Hank La

Since Specialization

Citations

This map shows the geographic impact of Hank La's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hank La with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hank La more than expected).

Fields of papers citing papers by Hank La

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hank La. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hank La. The network helps show where Hank La may publish in the future.

Co-authors

The 25 scholars most cited alongside Hank La, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hank La Line = papers co-authored together Hank La links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 23 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Pharmacokinetic–Pharmacodynamic Analysis of Vismodegib in Preclinical Models of Mutational and Ligand-Dependent Hedgehog Pathway Activation Clinical Cancer Research ·Harvey Wong, Bruno Alicke, Kristina West, Patrícia Pacheco, Hank La, Tom Januario, Robert L. Yauch, Frédéric J. de Sauvage, Stephen E. Gould	2011	96
2	Antitumor Activity of Targeted and Cytotoxic Agents in Murine Subcutaneous Tumor Models Correlates with Clinical Response Clinical Cancer Research ·Harvey Wong, Edna F. Choo, Bruno Alicke, Xiao Ding, Hank La, Erin McNamara, Frank‐Peter Theil, Jay Tibbitts, Lori S. Friedman, Cornelis E. C. A. Hop, Stephen E. Gould	2012	96
3	SAHA Enhances Synaptic Function and Plasticity In Vitro but Has Limited Brain Availability In Vivo and Does Not Impact Cognition PLoS ONE ·Jesse E. Hanson, Hank La, Emile G. Plise, Yung‐Hsiang Chen, Xiao Ding, Taleen Hanania, Emily Sabath, Vadim Alexandrov, Dani Brunner, Emer Leahy, Pascal Steiner, Lichuan Liu, Kimberly Scearce‐Levie, Qiang Zhou	2013	93
4	Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M Cancer Discovery ·Ho‐June Lee, Gabriele Schaefer, Timothy P. Heffron, Lily Shao, Xiaofen Ye, Steve Sideris, Shiva Malek, Emily Chan, Mark Merchant, Hank La, Savita Ubhayakar, Robert L. Yauch, Valentina Pirazzoli, Katerina Politi, Jeff Settleman	2012	68
5	Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists Bioorganic & Medicinal Chemistry Letters ·Benjamin P. Fauber, Alberto Gobbi, Kirk Robarge, Aihe Zhou, Adrian Barnard, Jianhua Cao, Yuzhong Deng, Céline Eidenschenk, Christine Everett, Arunima Ganguli, Julie A. Hawkins, Adam R. Johnson, Hank La, Maxine Norman, Gary Salmon, Susan Summerhill, Wenjun Ouyang, Wei Tang, Harvey Wong	2015	58
6	Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors Cancer Cell ·Ivana Yen, Fergus Shanahan, Mark Merchant, Christine Orr, Thomas Hunsaker, Matthew R. Durk, Hank La, Xiaolin Zhang, Scott E. Martin, Eva Lin, John S.D. Chan, Yihong Yu, Dhara N. Amin, Richard M. Neve, Amy Gustafson, Avinashnarayan Venkatanarayan, Scott A. Foster, Joachim Rudolph, Christiaan Klijn, Shiva Malek	2018	47
7	Discovery of 1-{4-[3-Fluoro-4-((3 S ,6 R )-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C (RORc or RORγ) Inverse Agonist Journal of Medicinal Chemistry ·Benjamin P. Fauber, Olivier René, Yuzhong Deng, Jason DeVoss, Céline Eidenschenk, Christine Everett, Arunima Ganguli, Alberto Gobbi, Julie A. Hawkins, Adam R. Johnson, Hank La, Justin Lesch, Peter Lockey, Maxine Norman, Wenjun Ouyang, Susan Summerhill, Harvey Wong	2015	46
8	Learning and Confirming with Preclinical Studies: Modeling and Simulation in the Discovery of GDC-0917, an Inhibitor of Apoptosis Proteins Antagonist Drug Metabolism and Disposition ·Harvey Wong, Stephen E. Gould, Nageshwar Budha, Walter C. Darbonne, Edward E. Kadel, Hank La, Bruno Alicke, Jason Halladay, Rebecca J. Erickson, Chia C. Portera, Anthony W. Tolcher, J. Infante, Michael Mamounas, John A. Flygare, Cornelis E. C. A. Hop, Wayne J. Fairbrother	2013	42
9	4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase Bioorganic & Medicinal Chemistry Letters ·Emily J. Hanan, Matt Baumgardner, Marian C. Bryan, Yuan Chen, Charles Eigenbrot, Peter W. Fan, Xiao‐Hui Gu, Hank La, Shiva Malek, Hans E. Purkey, Gabriele Schaefer, Stephen Schmidt, Steve Sideris, Ivana Yen, Christine Yu, Timothy P. Heffron	2015	39
10	Reduction in lipophilicity improved the solubility, plasma–protein binding, and permeability of tertiary sulfonamide RORc inverse agonists Bioorganic & Medicinal Chemistry Letters ·Benjamin P. Fauber, Olivier René, Gladys de Leon Boenig, Brenda Burton, Yuzhong Deng, Céline Eidenschenk, Christine Everett, Alberto Gobbi, S.G. Hymowitz, Adam R. Johnson, Hank La, Marya Liimatta, Peter Lockey, Maxine Norman, Wenjun Ouyang, Weiru Wang, Harvey Wong	2014	39
11	Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors Journal of Medicinal Chemistry ·James J. Crawford, Wendy Lee, Ignacio Aliagas, Simon Mathieu, Klaus P. Hoeflich, Wei Zhou, Weiru Wang, Lionel Rougé, Lesley Murray, Hank La, Ning Liu, Peter W. Fan, Jonathan Cheong, Christopher E. Heise, Sreemathy Ramaswamy, Robert Mintzer, Yanzhou Liu, Qi Chao, Joachim Rudolph	2015	29
12	In Vitro and In Vivo Evaluation of Amorphous Solid Dispersions Generated by Different Bench-Scale Processes, Using Griseofulvin as a Model Compound The AAPS Journal ·Po‐Chang Chiang, Yong Cui, Yingqing Ran, Joe Lubach, Kang-Jye Chou, Linda Bao, Jia Wei, Hank La, Jonathan Hau, Amy Sambrone, Ann Qin, Yuzhong Deng, Harvey Wong	2013	28
13	Interplay of Dissolution, Solubility, and Nonsink Permeation Determines the Oral Absorption of the Hedgehog Pathway Inhibitor GDC-0449 in Dogs: An Investigation Using Preclinical Studies and Physiologically Based Pharmacokinetic Modeling Drug Metabolism and Disposition ·Harvey Wong, Frank‐Peter Theil, Yong Cui, James C. Marsters, S. Cyrus Khojasteh, Laurent Vernillet, Hank La, Xi‐Ling Song, Hong Wang, Eric J. Morinello, Yuzhong Deng, Cornelis E. C. A. Hop	2010	17
14	Systemic Concentrations Can Limit the Oral Absorption of Poorly Soluble Drugs: An Investigation of Non-Sink Permeation Using Physiologically Based Pharmacokinetic Modeling Molecular Pharmaceutics ·Po‐Chang Chiang, Hank La, Haiming Zhang, Harvey Wong	2013	15
15	Cyclodextrin Reduces Intravenous Toxicity of a Model Compound Journal of Pharmaceutical Sciences ·Priscilla Mantik, Minli Xie, Harvey Wong, Hank La, Ronald W. Steigerwalt, Uday Devanaboyina, Geoffrey Ganem, Danny Shih, John A. Flygare, Wayne J. Fairbrother, Paroma Chakravarty, David Russell, Gilberto E. Fernandez, Ajit S. Narang	2019	13
16	Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Wendy Lee, James J. Crawford, Ignacio Aliagas, Lesley Murray, Suzanne Tay, Weiru Wang, Christopher E. Heise, Klaus P. Hoeflich, Hank La, Simon Mathieu, Robert Mintzer, Sreemathy Ramaswamy, Lionel Rougé, Joachim Rudolph	2016	12
17	Stereoselective supercritical fluidic chromatography –mass spectrometry (SFC-MS) as a fast bioanalytical tool to assess chiral inversion in vivo and in vitro International Journal of Mass Spectrometry ·Liuxi Chen, Brian Dean, Hank La, Yuan Chen, Xiaorong Liang	2019	12
18	Identification of N-sulfonyl-tetrahydroquinolines as RORc inverse agonists Bioorganic & Medicinal Chemistry Letters ·Benjamin P. Fauber, Alberto Gobbi, Pascal Savy, Brenda Burton, Yuzhong Deng, Christine Everett, Hank La, Adam R. Johnson, Peter Lockey, Maxine Norman, Harvey Wong	2015	10
19	Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series ACS Medicinal Chemistry Letters ·Joachim Rudolph, Ignacio Aliagas, James J. Crawford, Simon Mathieu, Wendy Lee, Qi Chao, Ping Dong, Lionel Rougé, Weiru Wang, Christopher E. Heise, Lesley Murray, Hank La, Yanzhou Liu, Gerard Manning, François Diederich, Klaus P. Hoeflich	2015	10
20	Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties Bioorganic & Medicinal Chemistry Letters ·Olivier René, Benjamin P. Fauber, Adrian Barnard, Kerry L. Chapman, Yuzhong Deng, Céline Eidenschenk, Christine Everett, Alberto Gobbi, Adam R. Johnson, Hank La, Maxine Norman, Gary Salmon, Susan Summerhill, Harvey Wong	2016	9

About Hank La

Hank La is a scholar working on Molecular Biology, Oncology, Immunology, Pharmacology and Cell Biology, having authored 23 papers that have together received 792 indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (5 papers), Cancer therapeutics and mechanisms (4 papers), Analytical Chemistry and Chromatography (3 papers), Retinoids in leukemia and cellular processes (3 papers), Protein Kinase Regulation and GTPase Signaling (3 papers), Psoriasis: Treatment and Pathogenesis (3 papers), Hedgehog Signaling Pathway Studies (2 papers) and Pharmacogenetics and Drug Metabolism (2 papers). The work is most often cited by research in Oncology (221 citations), Pharmaceutical Science (47 citations), Molecular Biology (428 citations), Modeling and Simulation (28 citations) and Pharmacology (44 citations). Hank La has collaborated with scholars based in United States, France and China. Frequent co-authors include Harvey Wong, Stephen E. Gould, Bruno Alicke, Xiao Ding, Robert L. Yauch, Yuzhong Deng, Cornelis E. C. A. Hop, Kristina West, Tom Januario and Frédéric J. de Sauvage. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Clinical Cancer Research, Journal of Medicinal Chemistry, Drug Metabolism and Disposition and Journal of Pharmaceutical Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Hank La

Impact in

Papers in i

In The Last Decade

Hank La

Peers

Countries citing papers authored by Hank La

Fields of papers citing papers by Hank La

All Works

About Hank La

Explore authors with similar magnitude of impact

Papers in