Simon Goodacre

1.4k citations

13 papers · 513 indexed · h-index 11

Impact in

Organic Chemistry top 5%
- Catalytic C–H Functionalization Methods
- Synthesis and Biological Evaluation
- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Synthesis and Reactivity of Heterocycles
- Catalytic Cross-Coupling Reactions
Pharmaceutical Science top 5%
- Fluorine in Organic Chemistry

Papers in ⓘ

Molecular Biology 9
- Phenothiazines and Benzothiazines Synthesis and Activities 3
- Receptor Mechanisms and Signaling 2
- Pharmacological Receptor Mechanisms and Effects 2
Organic Chemistry 5
- Synthesis and Biological Evaluation 3
- Synthesis and Reactivity of Heterocycles 2

Co-authors: David J. Hallett (7 shared papers)José L. Castro (4 shared papers)John Atack (5 shared papers)Keith A. Wafford (5 shared papers)Steve Thomas (3 shared papers)Emanuela Gancia (1 shared paper)Kevin J. Merchant (1 shared paper)Alexander C. Humphries (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Medicinal Chemistry (3 papers)ACS Medicinal Chemistry Letters (1 paper)The Journal of Organic Chemistry (1 paper)Journal of Psychopharmacology (1 paper)
Partner nations: United Kingdom United States Switzerland

In The Last Decade

Simon Goodacre

13 papers receiving 492 citations

Peers

Countries citing papers authored by Simon Goodacre

Since Specialization

Citations

This map shows the geographic impact of Simon Goodacre's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon Goodacre with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon Goodacre more than expected).

Fields of papers citing papers by Simon Goodacre

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon Goodacre. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon Goodacre. The network helps show where Simon Goodacre may publish in the future.

Co-authors

The 25 scholars most cited alongside Simon Goodacre, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon Goodacre Line = papers co-authored together Simon Goodacre links everyone, so they are left out of the graph.

All Works

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13 of 13 papers shown

#	Work
1	Imidazo[1,2-a]pyrimidines as Functionally Selective and Orally Bioavailable GABA_Aα2/α3 Binding Site Agonists for the Treatment of Anxiety Disorders Journal of Medicinal Chemistry ·Simon Goodacre, Leslie J. Street, David J. Hallett, James Crawforth, Sarah Kelly, Andrew P. Owens, Wesley Blackaby, Richard T. Lewis, Joanna L. Stanley, Alison J. Smith, Pushpinder Ferris, Bindi Sohal, Susan M. Cook, Andrew Pike, N. Brown, Keith A. Wafford, George Marshall, José L. Castro, John Atack	2005	121
2	8-Fluoroimidazo[1,2-a]pyridine: Synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of the GABAA receptor Bioorganic & Medicinal Chemistry Letters ·Alexander C. Humphries, Emanuela Gancia, Myra T. Gilligan, Simon Goodacre, David J. Hallett, Kevin J. Merchant, Steve Thomas	2006	96
3	3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as High Affinity, Selective, and Orally Bioavailable h5-HT_2A Receptor Antagonists Journal of Medicinal Chemistry ·Michael Rowley, David J. Hallett, Simon Goodacre, Christopher R. Moyes, James Crawforth, T. J. SPAREY, Smita S. Patel, Rose Marwood, Shil Patel, Steven R. Thomas, Laure Hitzel, Desmond O’Connor, Nicola Szeto, José L. Castro, Peter H. Hutson, Angus M. MacLeod	2001	93
4	Differential contribution of GABA_A receptor subtypes to the anticonvulsant efficacy of benzodiazepine site ligands Journal of Psychopharmacology ·Rosa Fradley, Martin R. Guscott, Sharlene Bull, David J. Hallett, Simon Goodacre, Keith A. Wafford, Elizabeth M. Garrett, Richard J. Newman, Gillian F. O’Meara, Paul J. Whiting, Thomas W. Rosahl, Gerard R. Dawson, David S. Reynolds, John Atack	2006	43
5	Imidazo[1,2-a]pyrimidines as functionally selective GABAA ligands Bioorganic & Medicinal Chemistry Letters ·Wesley Blackaby, John Atack, Frances A. Bromidge, José L. Castro, Simon Goodacre, David J. Hallett, Richard T. Lewis, George Marshall, Andrew Pike, Alison J. Smith, Leslie J. Street, David Tattersall, Keith A. Wafford	2006	36
6	Neighboring Group Participation of the Indole Nucleus: An Unusual DAST-Mediated Rearrangement Reaction The Journal of Organic Chemistry ·David J. Hallett, Ute Gerhard, Simon Goodacre, Laure Hitzel, T. J. SPAREY, Steven R. Thomas, Michael Rowley, Richard G. Ball	2000	24
7	3-(Piperazinylpropyl)indoles: Selective, Orally Bioavailable h5-HT_1DReceptor Agonists as Potential Antimigraine Agents Journal of Medicinal Chemistry ·Mark S. Chambers, Leslie J. Street, Simon Goodacre, Sarah C. Hobbs, Peter Hunt, Richard A. Jelley, Victor G. Matassa, Austin J. Reeve, Francine Sternfeld, Margaret S. Beer, Josephine A. Stanton, Denise Rathbone, Alan P. Watt, Angus M. MacLeod	1999	21
8	Imidazo[1,2-a]pyrazin-8-ones, imidazo[1,2-d][1,2,4]triazin-8-ones and imidazo[2,1-f][1,2,4]triazin-8-ones as α2/α3 subtype selective GABAA agonists for the treatment of anxiety Bioorganic & Medicinal Chemistry Letters ·Simon Goodacre, David J. Hallett, Robert W. Carling, José L. Castro, David S. Reynolds, Andrew Pike, Keith A. Wafford, Robert Newman, John Atack, Leslie J. Street	2005	19
9	Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1 Bioorganic & Medicinal Chemistry Letters ·Lewis Gazzard, B.A. Appleton, Kerry L. Chapman, Huifen Chen, Kevin Clark, Joy Drobnick, Simon Goodacre, Jason Halladay, Joseph P. Lyssikatos, Stephen Schmidt, Steve Sideris, Christian Wiesmann, Karen Williams, Wu Ping, Ivana Yen, Shiva Malek	2014	15
10	The in vivo properties of pagoclone in rat are most likely mediated by 5′-hydroxy pagoclone Neuropharmacology ·John Atack, Andy Pike, George Marshall, Joanna L. Stanley, Rachael J. Lincoln, Susan M. Cook, Richard T. Lewis, Wesley Blackaby, Simon Goodacre, Ruth M. McKernan, Gerard R. Dawson, Keith A. Wafford, David S. Reynolds	2006	14
11	Identification of an Orally Bioavailable, Potent, and Selective Inhibitor of GlyT1 ACS Medicinal Chemistry Letters ·Wesley Blackaby, Richard T. Lewis, Joanne L. Thomson, Andrew S. R. Jennings, Simon Goodacre, Leslie J. Street, Angus M. MacLeod, Andrew Pike, Suzanne Wood, Steve Thomas, Terry Brown, Alison J. Smith, Gopalan V. Pillai, Sarah Almond, Martin R. Guscott, H. Donald Burns, Waisi Eng, Christine Ryan, Jacquelynn J. Cook, Terence G. Hamill	2010	14
12	3-(4-Piperidinyl)- and 3-(8-aza-bicyclo[3.2.1]oct-3-yl)-2-phenyl-1H-indoles as bioavailable h5-HT2A antagonists Bioorganic & Medicinal Chemistry Letters ·James Crawforth, Simon Goodacre, Robert Maxey, Sylvie Bourrain, Smita S. Patel, Rosemarie Marwood, Desmond O’Connor, Richard H. Herbert, Peter H. Hutson, Michael Rowley	2000	10
13	Optimisation of a series of potent, selective and orally bioavailable GlyT1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Joanne L. Thomson, Wesley Blackaby, Andrew S. R. Jennings, Simon Goodacre, Andrew Pike, Steve Thomas, Terry Brown, Alison J. Smith, Gopalan V. Pillai, Leslie J. Street, Richard T. Lewis	2009	7

About Simon Goodacre

Simon Goodacre is a scholar working on Molecular Biology, Organic Chemistry, Cellular and Molecular Neuroscience, Biochemistry and Psychiatry and Mental health, having authored 13 papers that have together received 513 indexed citations. Recurring topics across this work include Neuroscience and Neuropharmacology Research (5 papers), Synthesis and Biological Evaluation (3 papers), Phenothiazines and Benzothiazines Synthesis and Activities (3 papers), Receptor Mechanisms and Signaling (2 papers), Amino Acid Enzymes and Metabolism (2 papers), Synthesis and Reactivity of Heterocycles (2 papers), Pharmacological Receptor Mechanisms and Effects (2 papers) and Pancreatic function and diabetes (1 paper). The work is most often cited by research in Organic Chemistry (334 citations), Pharmaceutical Science (62 citations), Cellular and Molecular Neuroscience (88 citations), Molecular Biology (176 citations) and Biochemistry (18 citations). Simon Goodacre has collaborated with scholars based in United Kingdom, United States and Switzerland. Frequent co-authors include David J. Hallett, José L. Castro, John Atack, Keith A. Wafford, Steve Thomas, Emanuela Gancia, Kevin J. Merchant, Alexander C. Humphries, James Crawforth and Andrew Pike. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, The Journal of Organic Chemistry and Journal of Psychopharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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