Stefan N. Constantinescu

19.9k total citations · 1 hit paper
172 papers, 11.3k citations indexed

About

Stefan N. Constantinescu is a scholar working on Genetics, Molecular Biology and Hematology. According to data from OpenAlex, Stefan N. Constantinescu has authored 172 papers receiving a total of 11.3k indexed citations (citations by other indexed papers that have themselves been cited), including 95 papers in Genetics, 77 papers in Molecular Biology and 74 papers in Hematology. Recurrent topics in Stefan N. Constantinescu's work include Myeloproliferative Neoplasms: Diagnosis and Treatment (89 papers), Cytokine Signaling Pathways and Interactions (53 papers) and Kruppel-like factors research (38 papers). Stefan N. Constantinescu is often cited by papers focused on Myeloproliferative Neoplasms: Diagnosis and Treatment (89 papers), Cytokine Signaling Pathways and Interactions (53 papers) and Kruppel-like factors research (38 papers). Stefan N. Constantinescu collaborates with scholars based in Belgium, France and United States. Stefan N. Constantinescu's co-authors include William Vainchenker, Judith Staerk, Harvey F. Lodish, François Delhommeau, Jean‐Luc Villeval, Hana Raslová, Nicole Casadevall, Chloé James, Catherine Lacout and Valérie Ugo and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Stefan N. Constantinescu

168 papers receiving 11.1k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

2005 2.5k citations Jean‐Pierre Le Couedic, Judith Staerk et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Stefan N. Constantinescu Belgium	52	5.6k	5.6k	4.5k	3.1k	1.9k	172	11.3k
D. Gary Gilliland United States	62	4.2k 0.7×	8.4k 1.5×	8.1k 1.8×	2.8k 0.9×	2.0k 1.1×	126	16.2k
Tessa L. Holyoake United Kingdom	59	4.7k 0.8×	3.8k 0.7×	7.5k 1.7×	2.2k 0.7×	2.1k 1.1×	219	11.1k
Róbert Královics Austria	45	7.2k 1.3×	5.5k 1.0×	5.3k 1.2×	1.0k 0.3×	2.8k 1.5×	134	9.8k
David C. Seldin United States	69	2.0k 0.3×	9.8k 1.8×	1.7k 0.4×	2.9k 0.9×	988 0.5×	202	12.5k
Christine Chomienne France	56	2.0k 0.3×	10.1k 1.8×	6.8k 1.5×	1.3k 0.4×	821 0.4×	248	12.8k
Dolors Colomer Spain	60	4.9k 0.9×	5.1k 0.9×	2.7k 0.6×	3.1k 1.0×	573 0.3×	280	12.0k
Martin Sattler United States	55	1.5k 0.3×	4.3k 0.8×	3.1k 0.7×	2.4k 0.8×	578 0.3×	151	8.6k
Paresh Vyas United Kingdom	52	1.8k 0.3×	4.4k 0.8×	5.1k 1.1×	1.3k 0.4×	305 0.2×	235	9.4k
Jeffrey Tyner United States	46	2.1k 0.4×	3.3k 0.6×	2.9k 0.6×	1.3k 0.4×	509 0.3×	238	7.1k
Stephen D. Nimer United States	64	2.8k 0.5×	7.5k 1.3×	6.8k 1.5×	3.4k 1.1×	246 0.1×	239	14.6k

Countries citing papers authored by Stefan N. Constantinescu

Since Specialization

Citations

This map shows the geographic impact of Stefan N. Constantinescu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stefan N. Constantinescu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stefan N. Constantinescu more than expected).

Fields of papers citing papers by Stefan N. Constantinescu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stefan N. Constantinescu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stefan N. Constantinescu. The network helps show where Stefan N. Constantinescu may publish in the future.

Co-authorship network of co-authors of Stefan N. Constantinescu

This figure shows the co-authorship network connecting the top 25 collaborators of Stefan N. Constantinescu. A scholar is included among the top collaborators of Stefan N. Constantinescu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stefan N. Constantinescu. Stefan N. Constantinescu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Defour, Jean‐Philippe, Emilie Leroy, Thomas Balligand, et al.. (2023). Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers. eLife. 12. 3 indexed citations

Papadopoulos, Nicolas, Allison Derenne, C. Pecquet, et al.. (2023). Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation. Nature Communications. 14(1). 9 indexed citations

Papadopoulos, Nicolas, et al.. (2022). Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates. Biomedicines. 10(11). 2753–2753. 12 indexed citations

Varghese, Leila N., Myriam Oufadem, Bénédicte Neven, et al.. (2021). CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag. Blood. 138(6). 480–485. 3 indexed citations

Marty, Caroline, C. Pecquet, Harini Nivarthi, et al.. (2015). Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis. Blood. 127(10). 1317–1324. 180 indexed citations

Chachoua, Ilyas, C. Pecquet, Mira El-Khoury, et al.. (2015). Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants. Blood. 127(10). 1325–1335. 223 indexed citations

Hornakova, Tekla, Sandrine Degryse, Olga Gielen, et al.. (2015). Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities. Journal of Biological Chemistry. 290(48). 29022–29034. 37 indexed citations

Mead, Janet E., Onima Chowdhury, Alexandra Dusa, et al.. (2012). GERMLINE ACTIVATING JAK2-MUTATION IN A FAMILY WITH HEREDITARY THROMBOCYTOSIS. Haematologica. 97. 146–147. 1 indexed citations

Hornakova, Tekla, et al.. (2011). Oncogenic JAK1 and JAK2-activating mutations resistant to ATP-competitive inhibitors. Haematologica. 96(6). 845–853. 54 indexed citations

10.

Hornakova, Tekla, Judith Staerk, Yohan Royer, et al.. (2009). Acute Lymphoblastic Leukemia-associated JAK1 Mutants Activate the Janus Kinase/STAT Pathway via Interleukin-9 Receptor α Homodimers. Journal of Biological Chemistry. 284(11). 6773–6781. 54 indexed citations

11.

Plo, Isabelle, Yanyan Zhang, Jean‐Pierre Le Couedic, et al.. (2009). An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia. The Journal of Experimental Medicine. 206(8). 1701–1707. 50 indexed citations

12.

Elliott, Joanne, Yvonne Suessmuth, Latanya M. Scott, et al.. (2009). SOCS3 TYROSINE PHOSPHORYLATION AS A BIG-MARKER FOR THE MYELOPROLIFERATIVE DISORDER-ASSOCIATED MUTANT JAK2 KINASES. Haematologica. 94. 358–358. 1 indexed citations

13.

Constantinescu, Stefan N., Michael Girardot, & C. Pecquet. (2008). Mining for JAK–STAT mutations in cancer. Trends in Biochemical Sciences. 33(3). 122–131. 122 indexed citations

14.

Gakovic, Milica, Josiane Ragimbeau, Véronique François, Stefan N. Constantinescu, & Sandra Pellegrini. (2008). The Stat3-activating Tyk2 V678F Mutant Does Not Up-regulate Signaling through the Type I Interferon Receptor but Confers Ligand Hypersensitivity to a Homodimeric Receptor. Journal of Biological Chemistry. 283(27). 18522–18529. 11 indexed citations

15.

Royer, Yohan, et al.. (2004). High-Throughput Gateway Bicistronic Retroviral Vectors for Stable Expression in Mammalian Cells: Exploring the Biologic Effects of STAT5 Overexpression. DNA and Cell Biology. 23(6). 355–365. 17 indexed citations

16.

Constantinescu, Stefan N.. (2003). Stemness, fusion and renewal of hematopoietic and embryonic stem cells. Journal of Cellular and Molecular Medicine. 7(2). 103–112. 27 indexed citations

17.

Huang, Lily, Stefan N. Constantinescu, & Harvey F. Lodish. (2001). The N-Terminal Domain of Janus Kinase 2 Is Required for Golgi Processing and Cell Surface Expression of Erythropoietin Receptor. Molecular Cell. 8(6). 1327–1338. 218 indexed citations

18.

Holland, Kerry A., Catherine M. Owczarek, Seung Y. Hwang, et al.. (1997). A Type I Interferon Signaling Factor, ISF21, Encoded on Chromosome 21 Is Distinct from Receptor Components and Their Down-regulation and Is Necessary for Transcriptional Activation of Interferon-regulated Genes. Journal of Biological Chemistry. 272(34). 21045–21051. 15 indexed citations

19.

Constantinescu, Stefan N., et al.. (1990). The Priming Effect of Human Interferon-α Is Mediated by Protein Kinase C. Journal of Interferon Research. 10(6). 589–597. 13 indexed citations

20.

Cernescu, C, Stefan N. Constantinescu, & Laurenţiu M. Popescu. (1990). Electron microscopic observations of vesicular stomatitis virus particles penetration in human fibroblasts.. PubMed. 41(2). 93–6. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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