Diederik Moechars

5.7k citations

53 papers · 3.8k indexed · 1 hit paper · h-index 28

Physiology top 1%
Molecular Biology top 10%
Cellular and Molecular Neuroscience top 1%
Neurology top 0.5%
Neurology top 2%

Co-authors: Bart De Strooper Patrik Verstreken Sara Calafate Arjan Buist Ilse Dewachter William P. Flavin Guy Daneels Soraia Barão
Topics: Alzheimer's disease research and treatments (28 papers)Neuroscience and Neuropharmacology Research (13 papers)Computational Drug Discovery Methods (10 papers)
Cited by: Neurology Physiology Cellular and Molecular Neuroscience
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Nature Communications
Partner nations: Belgium United States United Kingdom

In The Last Decade

Diederik Moechars

52 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

2019 624 citations Hannah Van Hove, Liesbet Martens et al. Nature Neuroscience profile →

Peers

Countries citing papers authored by Diederik Moechars

Since Specialization

Citations

This map shows the geographic impact of Diederik Moechars's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Diederik Moechars with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Diederik Moechars more than expected).

Fields of papers citing papers by Diederik Moechars

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Diederik Moechars. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Diederik Moechars. The network helps show where Diederik Moechars may publish in the future.

Co-authorship network of co-authors of Diederik Moechars

This figure shows the co-authorship network connecting the top 25 collaborators of Diederik Moechars. A scholar is included among the top collaborators of Diederik Moechars based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Diederik Moechars. Diederik Moechars is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	In vivo validation of novel non-invasive PHP.eB AAVs as a potential therapeutic approach for alpha-synucleinopathies 2025 ·Acta Neuropathologica Communications ·(unknown),(unknown),(unknown),Athanasios Stavropoulos,Christiane Volbracht,Louis De Muynck,Diederik Moechars,Ronald Melki,George K. Tofaris,Leonidas Stefanis,Maria Xilouri	0
2	Mutated Toll-like receptor 9 increases Alzheimer’s disease risk by compromising innate immunity protection 2023 ·Molecular Psychiatry ·Rita Cacace,(unknown),(unknown),Arjan Buist,(unknown),Anne Sieben,Patrick Cras,Rik Vandenberghe,Peter Paul De Deyn,Daniel Oehlrich,An De Bondt,Sebastiaan Engelborghs,Diederik Moechars,Christine Van Broeckhoven	7
3	microRNA-132 regulates gene expression programs involved in microglial homeostasis 2023 ·iScience ·Hannah Walgrave,Amber Penning,(unknown),(unknown),Kristofer Davie,(unknown),Leen Wolfs,Annerieke Sierksma,(unknown),(unknown),Nicola Thrupp,Lujia Zhou,Diederik Moechars,Renzo Mancuso,Mark Fiers,Andrew J.M. Howden,Bart De Strooper,Evgenia Salta	28
4	A Brain-Penetrant and Bioavailable Pyrazolopiperazine BACE1 Inhibitor Elicits Sustained Reduction of Amyloid β In Vivo 2021 ·ACS Medicinal Chemistry Letters ·Aldo Peschiulli,Daniel Oehlrich,Michiel Van Gool,Nigel Austin,Sven Van Brandt,(unknown),(unknown),Ann Vos,Gary Tresadern,Frederik Rombouts,Gregor J. Macdonald,Diederik Moechars,Andrés A. Trabanco,Harrie J. M. Gijsen	7
5	Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays 2020 ·Journal of Biological Chemistry ·Alex Crowe,Mark J. Henderson,Johnathon D. Anderson,Steven A. Titus,Alexey Zakharov,Anton Simeonov,Arjan Buist,Charlotte Delay,Diederik Moechars,John Q. Trojanowski,Virginia M.‐Y. Lee,Kurt R. Brunden	14
6	Clinical evaluation of [18F] JNJ-64326067, a novel candidate PET tracer for the detection of tau pathology in Alzheimer’s disease 2020 ·European Journal of Nuclear Medicine and Molecular Imaging ·Mark E. Schmidt,Luc Janssens,Diederik Moechars,Frederik Rombouts,Maarten Timmers,Olivier Barret,Cristian Constantinescu,Jennifer Madonia,David Russell,Christine Sandiego,Hartmuth C. Kolb	14
7	Discovery of N-(4-[¹⁸F]Fluoro-5-methylpyridin-2-yl)isoquinolin-6-amine (JNJ-64326067), a New Promising Tau Positron Emission Tomography Imaging Tracer 2019 ·Journal of Medicinal Chemistry ·Frederik Rombouts,Lieven Declercq,José-Ignacio Andrés,Astrid Bottelbergs,Lu Chen,Laura Iturrino,(unknown),(unknown),Fengbin Song,Cindy Wintmolders,Stijn Wuyts,Chunfang Xia,Paula te Riele,Guy Bormans,Rik Vandenberghe,Hartmuth C. Kolb,Diederik Moechars	27
8	A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environmentbreakdown → 2019 ·Nature Neuroscience ·Hannah Van Hove,Liesbet Martens,Isabelle Scheyltjens,Karen De Vlaminck,Ana Rita Pombo Antunes,Sofie De Prijck,Niels Vandamme,Sebastiaan De Schepper,Gert Van Isterdael,Charlotte L. Scott,Jeroen Aerts,Geert Berx,Guy E. Boeckxstaens,Roosmarijn E. Vandenbroucke,Lars Vereecke,Diederik Moechars,Martin Guilliams,Jo A. Van Ginderachter,Yvan Saeys,Kiavash Movahedi	624
9	Optimization of 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors Toward a Clinical Candidate 2018 ·Journal of Medicinal Chemistry ·Harrie J. M. Gijsen,(unknown),(unknown),(unknown),Gregor J. Macdonald,(unknown),Daniel Oehlrich,Hana Prokopcová,Frederik Rombouts,(unknown),Andrés A. Trabanco,Sven Van Brandt,(unknown),Michiel Van Gool,Nigel Austin,Herman Borghys,(unknown),Diederik Moechars	11
10	Fragment Binding to β-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches 2017 ·ACS Omega ·Frederik Rombouts,Richard Alexander,Erna Cleiren,Alex De Groot,(unknown),(unknown),Katleen Fierens,Stefan Masure,Diederik Moechars,Martina Palomino‐Schätzlein,Antonio Pineda‐Lucena,Andrés A. Trabanco,(unknown),Ann Vos,Gary Tresadern	13
11	Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo 2017 ·Acta Neuropathologica ·Peng Wang,Gérard Joberty,Arjan Buist,(unknown),Ilie‐Cosmin Stancu,Bruno Vasconcelos,Nathalie Pierrot,Maria Faelth-Savitski,Pascal Kienlen‐Campard,Jean‐Noël Octave,Marcus Bantscheff,Gerard Drewes,Diederik Moechars,Ilse Dewachter	91
12	Emergence of early alterations in network oscillations and functional connectivity in a tau seeding mouse model of Alzheimer’s disease pathology 2017 ·Scientific Reports ·A. Ahnaou,Diederik Moechars,(unknown),R. Biermans,Nikolay V. Manyakov,Astrid Bottelbergs,Cindy Wintmolders,Kristof Van Kolen,Tom Van de Casteele,John A. Kemp,Wilhelmus Drinkenburg	70
13	BACE1 Physiological Functions May Limit Its Use as Therapeutic Target for Alzheimer's Disease 2016 ·Trends in Neurosciences ·Soraia Barão,Diederik Moechars,Stefan F. Lichtenthaler,Bart De Strooper	124
14	Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation 2015 ·Cell Reports ·Sara Calafate,Arjan Buist,Katarzyna Miśkiewicz,V. A. Vijayan,Guy Daneels,Bart De Strooper,Joris de Wit,Patrik Verstreken,Diederik Moechars	200
15	Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice 2015 ·Acta Neuropathologica ·Ilie‐Cosmin Stancu,Bruno Vasconcelos,Laurence Ris,Peng Wang,Arnauld Villers,Eve Peeraer,Arjan Buist,Dick Terwel,(unknown),(unknown),Nathalie Pierrot,Cindy Casteels,Guy Bormans,Pascal Kienlen‐Campard,Jean‐Noël Octave,Diederik Moechars,Ilse Dewachter	119
16	GSK-3β dysregulation contributes to parkinson’s-like pathophysiology with associated region-specific phosphorylation and accumulation of tau and α-synuclein 2014 ·Cell Death and Differentiation ·Joel J. Credle,Jessica George,(unknown),Valeriy Duka,(unknown),(unknown),Olga Rodriguez,Tyrell Simkins,Melanie Winter,Diederik Moechars,Thomas Steckler,John L. Goudreau,David I. Finkelstein,A Sidhu	95
17	Time course of tinnitus development following noise exposure in mice 2012 ·Journal of Neuroscience Research ·Jeremy G. Turner,(unknown),Larry F. Hughes,Diederik Moechars,Susan E. Shore	62
18	Requirement of central ghrelin signaling for alcohol reward 2009 ·Proceedings of the National Academy of Sciences ·Elisabet Jerlhag,Emil Egecioglu,Sara Landgren,Nicolas Salomé,Markus Heilig,Diederik Moechars,Rakesh Datta,Daniel Perrissoud,Suzanne L. Dickson,Jörgen A. Engel	349
19	Vesicular Glutamate Transporter VGLUT1 Has a Role in Hippocampal Long-Term Potentiation and Spatial Reversal Learning 2009 ·Cerebral Cortex ·Detlef Balschun,Diederik Moechars,Zsuzsanna Callaerts‐Vegh,Ben Vermaercke,Nathalie Van Acker,Luc Andries,Rudi D’Hooge	98
20	Molecular cloning and sequencing of the murine alpha-2-macroglobulin receptor cDNA 1993 ·Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·Fred Van Leuven,(unknown),(unknown),Lut Overbergh,Bart De Strooper,Carl Hilliker,Kristin Lorent,(unknown),Lieve Umans,Sophie Torrekens,Lutgarde Serneels,Diederik Moechars,Herman Van den Berghe	27

About Diederik Moechars

Diederik Moechars is a scholar working on Physiology, Neurology and Cellular and Molecular Neuroscience, having authored 53 papers that have together received 3.8k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (28 papers), Neuroscience and Neuropharmacology Research (13 papers) and Computational Drug Discovery Methods (10 papers). The work is most often cited by research in Neurology (930 citations), Physiology (1.9k citations) and Cellular and Molecular Neuroscience (1.1k citations). Diederik Moechars has collaborated with scholars based in Belgium, United States and United Kingdom. Frequent co-authors include Bart De Strooper, Patrik Verstreken, Sara Calafate, Arjan Buist, Ilse Dewachter, William P. Flavin, Guy Daneels, Soraia Barão, Katarzyna Miśkiewicz and Joris de Wit. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact