Holly Kordasiewicz

7.8k citations

59 papers · 4.9k indexed · 3 hit papers · h-index 29

Molecular Biology top 2%
Cellular and Molecular Neuroscience top 0.5%
Neurology top 0.5%
Genetics top 0.5%
Physiology top 5%

Co-authors: C. Frank Bennett Don W. Cleveland Eric E. Swayze Curt Mazur Edward V. Wancewicz G Yeo Shuo‐Chien Ling Stephanie C. Huelga
Topics: Genetic Neurodegenerative Diseases (26 papers)Mitochondrial Function and Pathology (13 papers)Neurogenetic and Muscular Disorders Research (10 papers)
Cited by: Neurology Genetics Cellular and Molecular Neuroscience
Journals: Cell Proceedings of the National Academy of Sciences Nucleic Acids Research
Partner nations: United States Canada United Kingdom

In The Last Decade

Holly Kordasiewicz

57 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

2011 959 citations Edward V. Wancewicz, Curt Mazur et al. profile →
Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis

2012 563 citations Holly Kordasiewicz, Lisa M. Stanek et al. Neuron profile →
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy

2017 362 citations Holly Kordasiewicz, Eric E. Swayze et al. profile →

Peers

Countries citing papers authored by Holly Kordasiewicz

Since Specialization

Citations

This map shows the geographic impact of Holly Kordasiewicz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Holly Kordasiewicz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Holly Kordasiewicz more than expected).

Fields of papers citing papers by Holly Kordasiewicz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Holly Kordasiewicz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Holly Kordasiewicz. The network helps show where Holly Kordasiewicz may publish in the future.

Co-authorship network of co-authors of Holly Kordasiewicz

This figure shows the co-authorship network connecting the top 25 collaborators of Holly Kordasiewicz. A scholar is included among the top collaborators of Holly Kordasiewicz based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Holly Kordasiewicz. Holly Kordasiewicz is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Altered huntingtin−chromatin interactions predict transcriptional and epigenetic changes in Huntington's disease 2025 ·Disease Models & Mechanisms ·Jocelynn R. Pearl,Amol C. Shetty,Jeffrey P. Cantle,(unknown),R R Bragg,(unknown),Holly Kordasiewicz,Leroy Hood,Nathan D. Price,Seth A. Ament,Jeffrey B. Carroll	1
2	Acute neuronal inhibition response caused by phosphorothioate antisense oligonucleotides following local delivery to the central nervous system 2025 ·Nucleic Acids Research ·(unknown),(unknown),Curt Mazur,(unknown),Oleksandr Platoshyn,(unknown),(unknown),(unknown),Sebastien A. Burel,(unknown),Thomas A. Zanardi,(unknown),(unknown),Scott P. Henry,Eric E. Swayze,Berit Powers,Holly Kordasiewicz	0
3	A single-cell map of antisense oligonucleotide activity in the brain 2023 ·Nucleic Acids Research ·(unknown),(unknown),Naeem Nadaf,Charles Vanderburg,Sean Simmons,(unknown),(unknown),(unknown),(unknown),(unknown),Holly Kordasiewicz,Hien Zhao,Sonia M. Vallabh,Eric Vallabh Minikel	24
4	ASO-mediated knockdown or kinase inhibition of G2019S-Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages 2023 ·Molecular Therapy — Nucleic Acids ·Rebecca L. Wallings,(unknown),(unknown),(unknown),(unknown),Holly Kordasiewicz,Warren D. Hirst,Malú G. Tansey	7
5	Regional variability and genotypic and pharmacodynamic effects on PrP concentration in the CNS 2022 ·JCI Insight ·(unknown),Hien Zhao,Andrew G. Reidenbach,(unknown),Eric Kuhn,Jill O’Moore,Patrick M. Dooley,(unknown),Curt Mazur,Shona W. Allen,Bianca A. Trombetta,Alison J. McManus,(unknown),(unknown),Deborah E. Cabin,Holly Kordasiewicz,Joel Mathews,Steven E. Arnold,Sonia M. Vallabh,Eric Vallabh Minikel	10
6	Gys1 antisense therapy rescues neuropathological bases of murine Lafora disease 2021 ·Brain ·Saija Ahonen,Silvia Nitschke,Tamar R. Grossman,Holly Kordasiewicz,Peixiang Wang,Xiaochu Zhao,(unknown),Sahba Kasiri,Felix Nitschké,Berge A. Minassian	40
7	LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson’s Disease Mouse Model 2021 ·Molecular Therapy — Nucleic Acids ·Hien Zhao,Neena S. John,Vedad Delic,(unknown),Aneeza Kim,Andreas Weihofen,Eric E. Swayze,Holly Kordasiewicz,Andrew B. West,Laura A. Volpicelli‐Daley	2
8	The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration 2020 ·Nucleic Acids Research ·Paymaan Jafar‐Nejad,Berit Powers,Armand Soriano,Hien Zhao,Daniel A. Norris,John Matson,(unknown),(unknown),(unknown),Seung Chun,Curt Mazur,Holly Kordasiewicz,Eric E. Swayze,Frank Rigo	62
9	Antisense oligonucleotides for the treatment of neurodegenerative diseases 2020 ·Holly Kordasiewicz	1
10	Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment 2020 ·Molecular Therapy — Nucleic Acids ·Brennon O’Callaghan,(unknown),(unknown),Holly Kordasiewicz,Tracy Cole,Lisa Duvick,(unknown),(unknown),(unknown),Michael A. Benneyworth,(unknown),(unknown),(unknown),Christine Henzler,Harry T. Orr	16
11	Antisense Drugs Make Sense for Neurological Diseases 2020 ·The Annual Review of Pharmacology and Toxicology ·C. Frank Bennett,Holly Kordasiewicz,Don W. Cleveland	68
12	Antisense oligonucleotide–mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles 2018 ·JCI Insight ·(unknown),Holly Kordasiewicz,Brennon O’Callaghan,(unknown),(unknown),Lisa Duvick,Eric E. Swayze,(unknown),(unknown),Michael A. Benneyworth,(unknown),(unknown),Chen Zhao,Judit Perez Ortiz,H. Brent Clark,Gülin Öz,Sarah N. Larson,Huda Y. Zoghbi,Christine Henzler,Harry T. Orr	87
13	Translating Antisense Technology into a Treatment for Huntington’s Disease 2018 ·Methods in molecular biology ·Roger Lane,(unknown),Tiffany Baumann,Marc Gleichmann,Dan Norris,C. Frank Bennett,Holly Kordasiewicz	32
14	Antisense oligonucleotides selectively suppress target RNA in nociceptive neurons of the pain system and can ameliorate mechanical pain 2017 ·Pain ·Apoorva Mohan,Bethany Fitzsimmons,Hien Zhao,Yuhong Jiang,Curt Mazur,Eric E. Swayze,Holly Kordasiewicz	22
15	Intrathecal administration of antisense oligonucleotide against p38α but not p38β MAP kinase isoform reduces neuropathic and postoperative pain and TLR4-induced pain in male mice 2017 ·Brain Behavior and Immunity ·Xin Luo,Bethany Fitzsimmons,Apoorva Mohan,Linlin Zhang,Niccolò Terrando,Holly Kordasiewicz,Ru‐Rong Ji	55
16	Allele-Specific Suppression of Mutant Huntingtin Using Antisense Oligonucleotides: Providing a Therapeutic Option for All Huntington Disease Patients 2014 ·PLoS ONE ·Niels H. Skotte,Amber L. Southwell,Michael E. Østergaard,Jeffrey B. Carroll,Simon C. Warby,Crystal N. Doty,Eugenia Petoukhov,Kuljeet Vaid,Holly Kordasiewicz,Andrew T. Watt,Susan M. Freier,Gene Hung,Punit P. Seth,C. Frank Bennett,Eric E. Swayze,Michael R. Hayden	85
17	In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides 2014 ·Molecular Therapy ·Amber L. Southwell,Niels H. Skotte,Holly Kordasiewicz,Michael E. Østergaard,Andrew T. Watt,Jeffrey B. Carroll,Crystal N. Doty,Erika B. Villanueva,Eugenia Petoukhov,Kuljeet Vaid,Yuanyun Xie,Susan M. Freier,Eric E. Swayze,Punit P. Seth,(unknown),Michael R. Hayden	107
18	Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesisbreakdown → 2012 ·Neuron ·Holly Kordasiewicz,Lisa M. Stanek,Edward V. Wancewicz,Curt Mazur,(unknown),(unknown),Jonathan W. Artates,Andreas Weiss,Seng H. Cheng,Lamya S. Shihabuddin,Gene Hung,C. Frank Bennett,Don W. Cleveland	563
19	Dominant-negative suppression of Cav2.1 currents by α12.1 truncations requires the conserved interaction domain for β subunits 2006 ·Molecular and Cellular Neuroscience ·Robert S. Raike,Holly Kordasiewicz,Randall M. Thompson,Christopher M. Gómez	22
20	C-termini of P/Q-type Ca 2+ channel α1A subunits translocate to nuclei and promote polyglutamine-mediated toxicity 2006 ·Human Molecular Genetics ·Holly Kordasiewicz,Randall M. Thompson,H. Brent Clark,Christopher M. Gómez	107

About Holly Kordasiewicz

Holly Kordasiewicz is a scholar working on Cellular and Molecular Neuroscience, Neurology and Genetics, having authored 59 papers that have together received 4.9k indexed citations. Recurring topics across this work include Genetic Neurodegenerative Diseases (26 papers), Mitochondrial Function and Pathology (13 papers) and Neurogenetic and Muscular Disorders Research (10 papers). The work is most often cited by research in Neurology (1.8k citations), Genetics (1.1k citations) and Cellular and Molecular Neuroscience (1.9k citations). Holly Kordasiewicz has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include C. Frank Bennett, Don W. Cleveland, Eric E. Swayze, Curt Mazur, Edward V. Wancewicz, G Yeo, Shuo‐Chien Ling, Stephanie C. Huelga, Magdalini Polymenidou and Clotilde Lagier‐Tourenne. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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