Gene Hung

11.3k total citations · 6 hit papers
69 papers, 8.6k citations indexed

About

Gene Hung is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Genetics. According to data from OpenAlex, Gene Hung has authored 69 papers receiving a total of 8.6k indexed citations (citations by other indexed papers that have themselves been cited), including 47 papers in Molecular Biology, 18 papers in Cellular and Molecular Neuroscience and 15 papers in Genetics. Recurrent topics in Gene Hung's work include Genetic Neurodegenerative Diseases (16 papers), RNA Research and Splicing (13 papers) and Neurogenetic and Muscular Disorders Research (12 papers). Gene Hung is often cited by papers focused on Genetic Neurodegenerative Diseases (16 papers), RNA Research and Splicing (13 papers) and Neurogenetic and Muscular Disorders Research (12 papers). Gene Hung collaborates with scholars based in United States, Germany and Canada. Gene Hung's co-authors include C. Frank Bennett, Frank Rigo, Yimin Hua, Adrian R. Krainer, Kentaro Sahashi, David L. Spector, Gayatri Arun, Marco A. Passini, Jeff Hsu and Youngsoo Kim and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Gene Hung

67 papers receiving 8.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

2012 1.3k citations Tony Gutschner, Monika Hämmerle et al. Cancer Research profile →
Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study

2016 736 citations Richard S. Finkel, Claudia A. Chiriboga et al. profile →
HER-2/neu gene amplification characterized by fluorescence in situ hybridization: poor prognosis in node-negative breast carcinomas.

1997 643 citations Michael F. Press, Leslie Bernstein et al. Journal of Clinical Oncology profile →
Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis

2012 563 citations Holly Kordasiewicz, Lisa M. Stanek et al. Neuron profile →
Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

2011 556 citations Yimin Hua, Kentaro Sahashi et al. Nature profile →
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model

2010 501 citations Yimin Hua, Kentaro Sahashi et al. Genes & Development profile →

Peers

Countries citing papers authored by Gene Hung

Since Specialization

Citations

This map shows the geographic impact of Gene Hung's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gene Hung with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gene Hung more than expected).

Fields of papers citing papers by Gene Hung

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gene Hung. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gene Hung. The network helps show where Gene Hung may publish in the future.

Co-authorship network of co-authors of Gene Hung

This figure shows the co-authorship network connecting the top 25 collaborators of Gene Hung. A scholar is included among the top collaborators of Gene Hung based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gene Hung. Gene Hung is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Inhibition of Kirsten-Ras reduces fibrosis and protects against renal dysfunction in a mouse model of chronic folic acid nephropathy 2019 ·Scientific Reports ·Lucy J. Newbury, (unknown), Gene Hung, Bruce M. Hendry, Claire C. Sharpe	20
2	Interim Results of a Phase 2 Clinical Study of Nusinersen (ISIS-SMNRx) in Patients with Infantile-Onset Spinal Muscular Atrophy (P5.004) 2016 ·Neurology ·Richard S. Finkel, Claudia A. Chiriboga, Jiri Vajsar, John Day, Jacqueline Montes, Darryl C. De Vivo, Mason Yamashita, Frank Rigo, Gene Hung, Eugene Schneider, Daniel A. Norris, Shuting Xia, Frank Bennett, Kathie M. Bishop	5
3	Effects of Repeated Complement Activation Associated with Chronic Treatment of Cynomolgus Monkeys with 2′- O -Methoxyethyl Modified Antisense Oligonucleotide 2016 ·Nucleic Acid Therapeutics ·Lijiang Shen, (unknown), Gene Hung, (unknown), Rie Kikkawa, John Matson, (unknown), Todd Machemer, Patricia C. Giclas, Scott P. Henry	18
4	Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice 2015 ·Immunobiology ·Tamar R. Grossman, Lisa Hettrick, Robert B. Johnson, Gene Hung, Raechel Peralta, Andrew T. Watt, Scott P. Henry, Peter Adamson, Brett P. Monia, Michael L. McCaleb	27
5	Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts 2015 ·Nucleic Acids Research ·Sebastien A. Burel, Christopher E. Hart, (unknown), (unknown), Todd Machemer, Melanie Katz, Andy Watt, Huynh‐Hoa Bui, Husam S. Younis, Mahyar Sabripour, Susan M. Freier, Gene Hung, (unknown), Thazha P. Prakash, Punit P. Seth, Eric E. Swayze, C. Frank Bennett, Stanley T. Crooke, Scott P. Henry	148
6	Allele-Specific Suppression of Mutant Huntingtin Using Antisense Oligonucleotides: Providing a Therapeutic Option for All Huntington Disease Patients 2014 ·PLoS ONE ·Niels H. Skotte, Amber L. Southwell, Michael E. Østergaard, Jeffrey B. Carroll, Simon C. Warby, Crystal N. Doty, Eugenia Petoukhov, Kuljeet Vaid, Holly Kordasiewicz, Andrew T. Watt, Susan M. Freier, Gene Hung, Punit P. Seth, C. Frank Bennett, Eric E. Swayze, Michael R. Hayden	85
7	Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy 2014 ·Cell Reports ·Andrew P. Lieberman, Zhigang Yu, Sue Murray, Raechel Peralta, Audrey Low, Shuling Guo, Xing Yu, Constanza J. Cortés, C. Frank Bennett, Brett P. Monia, Albert R. La Spada, Gene Hung	128
8	Treatment Of Spinocerebellar Ataxia Type 2 (SCA2) with MOE Antisense Oligonucleotides (S47.006) 2014 ·Neurology ·Daniel R. Scoles, Gene Hung, Lance Pflieger, Khanh K. Thai, Frank Bennett, Stefan M. Pulst	1
9	The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells breakdown → 2012 ·Cancer Research ·Tony Gutschner, Monika Hämmerle, Moritz F. Eissmann, Jeff Hsu, Youngsoo Kim, Gene Hung, Alexey S. Revenko, Gayatri Arun, Marion Stentrup, Matthias Groß, Martin Zörnig, A. Robert MacLeod, David L. Spector, Sven Diederichs	1307
10	Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis breakdown → 2012 ·Neuron ·Holly Kordasiewicz, Lisa M. Stanek, Edward V. Wancewicz, Curt Mazur, (unknown), (unknown), Jonathan W. Artates, Andreas Weiss, Seng H. Cheng, Lamya S. Shihabuddin, Gene Hung, C. Frank Bennett, Don W. Cleveland	563
11	The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult 2012 ·Cell Reports ·Bin Zhang, Gayatri Arun, Yuntao S. Mao, Zsolt I. Lázár, Gene Hung, Gourab Bhattacharjee, Xiaokun Xiao, Carmen J. Booth, Jie Wu, Chaolin Zhang, David L. Spector	493
12	Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model breakdown → 2011 ·Nature ·Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung, Guy Horev, C. Frank Bennett, Adrian R. Krainer	556
13	Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin 2011 ·Molecular Therapy ·Jeffrey B. Carroll, Simon C. Warby, Amber L. Southwell, Crystal N. Doty, Sarah Greenlee, Niels H. Skotte, Gene Hung, C. Frank Bennett, Susan M. Freier, Michael R. Hayden	225
14	Suppression of choroid plexus transthyretin levels by antisense oligonucleotide treatment 2010 ·Amyloid ·Merrill D. Benson, Richard Smith, Gene Hung, Barbara Kluve‐Beckerman, Aaron D. Showalter, Kyle W. Sloop, Brett P. Monia	34
15	Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model breakdown → 2010 ·Genes & Development ·Yimin Hua, Kentaro Sahashi, Gene Hung, Frank Rigo, Marco A. Passini, C. Frank Bennett, Adrian R. Krainer	501
16	Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein 2006 ·Proceedings of the National Academy of Sciences ·Deborah Chadee, Da-Zhong Xu, Gene Hung, Ali Andalibi, David Lim, Zhijun Luo, David H. Gutmann, John Kyriakis	78
17	Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals 2006 ·Nucleic Acids Research ·Eric E. Swayze, Andrew Siwkowski, Edward V. Wancewicz, Michael T. Migawa, Tadeusz K. Wyrzykiewicz, Gene Hung, Brett P. Monia, (unknown)	349
18	Eradication of murine mammary adenocarcinoma through HSVtk expression directed by the glucose-starvation inducible grp78 promoter 2000 ·Breast Cancer Research and Treatment ·Xinke Chen, (unknown), Gunther Dennert, Gene Hung, Amy S. Lee	19
19	HER-2/neu gene amplification characterized by fluorescence in situ hybridization: poor prognosis in node-negative breast carcinomas. breakdown → 1997 ·Journal of Clinical Oncology ·Michael F. Press, Leslie Bernstein, P. Thomas, L F Meisner, Jian Zhou, Yanhui Ma, Gene Hung, Robert A. Robinson, C Harris, Adel K. El‐Naggar, Dennis J. Slamon, (unknown), Jeffrey S. Ross, S R Wolman, Kerry Flom	643
20	Amplification and overexpression of HER-2/neu in carcinomas of the salivary gland: correlation with poor prognosis. 1994 ·PubMed ·Michael F. Press, Malcolm C. Pike, Gene Hung, Jian Zhou, Yanling Ma, Jay George, Jeanne Dietz‐Band, William James, Dennis J. Slamon, John G. Batsakis	176

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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