Frank Rigo

19.7k total citations · 10 hit papers
141 papers, 11.2k citations indexed

About

Frank Rigo is a scholar working on Molecular Biology, Genetics and Cellular and Molecular Neuroscience. According to data from OpenAlex, Frank Rigo has authored 141 papers receiving a total of 11.2k indexed citations (citations by other indexed papers that have themselves been cited), including 110 papers in Molecular Biology, 43 papers in Genetics and 31 papers in Cellular and Molecular Neuroscience. Recurrent topics in Frank Rigo's work include RNA Research and Splicing (49 papers), Neurogenetic and Muscular Disorders Research (43 papers) and RNA modifications and cancer (37 papers). Frank Rigo is often cited by papers focused on RNA Research and Splicing (49 papers), Neurogenetic and Muscular Disorders Research (43 papers) and RNA modifications and cancer (37 papers). Frank Rigo collaborates with scholars based in United States, Germany and Canada. Frank Rigo's co-authors include C. Frank Bennett, Adrian R. Krainer, Yimin Hua, Gene Hung, Kentaro Sahashi, Seung Chun, Marco A. Passini, Amanda J. Ward, Harold G. Martinson and Guy Horev and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Frank Rigo

135 papers receiving 11.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)

2016 863 citations Frank Rigo et al. profile →
Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study

2016 736 citations Frank Rigo, Gene Hung et al. profile →
RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

2013 670 citations Frank Rigo, C. Frank Bennett et al. profile →
Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

2011 556 citations Yimin Hua, Kentaro Sahashi et al. Nature profile →
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model

2010 501 citations Yimin Hua, Kentaro Sahashi et al. profile →
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion

2013 493 citations Frank Rigo, C. Frank Bennett et al. Science Translational Medicine profile →
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice

2017 396 citations Paymaan Jafar‐Nejad, Armand Soriano et al. Nature profile →
Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

2014 378 citations Seung Chun, C. Frank Bennett et al. Nature profile →
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration

2019 339 citations C. Frank Bennett, Frank Rigo et al. Nature Neuroscience profile →
Stress Granule Assembly Disrupts Nucleocytoplasmic Transport

2018 279 citations Alyssa N. Coyne, Frank Rigo et al. profile →

Peers

Countries citing papers authored by Frank Rigo

Since Specialization

Citations

This map shows the geographic impact of Frank Rigo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Rigo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Rigo more than expected).

Fields of papers citing papers by Frank Rigo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Rigo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Rigo. The network helps show where Frank Rigo may publish in the future.

Co-authorship network of co-authors of Frank Rigo

This figure shows the co-authorship network connecting the top 25 collaborators of Frank Rigo. A scholar is included among the top collaborators of Frank Rigo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank Rigo. Frank Rigo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Therapeutic antisense oligonucleotide mitigates retinal dysfunction in a pig model of CLN3 Batten disease 2025 ·Nucleic Acids Research ·(unknown), (unknown), Vicki J. Swier, Wanda Pfeifer, (unknown), Katrina Albert, John L. Hunyara, (unknown), (unknown), (unknown), Frank Rigo, (unknown), Paymaan Jafar‐Nejad, Jill M. Weimer, Arlene V. Drack, Michelle L. Hastings	0
2	A Workflow for Transcriptome-Wide Assessment of Antisense Oligonucleotide Selectivity 2025 ·Nucleic Acid Therapeutics ·Sagar Damle, Andy Watt, Steven Kuntz, (unknown), (unknown), (unknown), Christine C. Quirk, (unknown), (unknown), Christopher E. Hart, Frank Rigo	0
3	Differential effects of SARM1 inhibition in traumatic glaucoma and EAE optic neuropathies 2023 ·Molecular Therapy — Nucleic Acids ·Pingting Liu, Wei Chen, Haowen Jiang, Haoliang Huang, Liping Liu, Fang Fang, Liang Li, Xue Feng, Dong Liu, Roopa Dalal, Yang Sun, Paymaan Jafar‐Nejad, Karen Ling, Frank Rigo, Jiangbin Ye, Yang Hu	21
4	Reduction of nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43–related neurodegeneration 2023 ·Journal of Clinical Investigation ·Leon Tejwani, Youngseob Jung, Hiroshi Kokubu, (unknown), (unknown), Chang‐Woo Lee, (unknown), Jong Seo Lee, Yangfei Xiang, (unknown), Armand Soriano, (unknown), (unknown), (unknown), Hyoungseok Ju, Clara Liao, (unknown), Frank Rigo, Paymaan Jafar‐Nejad, Janghoo Lim	9
5	ASO silencing of a glycosyltransferase, Poglut1, improves the liver phenotypes in mouse models of Alagille syndrome 2023 ·Hepatology ·Nima Niknejad, (unknown), (unknown), Neda Zarrin‐Khameh, (unknown), Armand Soriano, (unknown), (unknown), Kari A. Huppert, Frank Rigo, Stacey S. Huppert, Paymaan Jafar‐Nejad, Hamed Jafar‐Nejad	5
6	Modulation of Gene Expression in the Eye with Antisense Oligonucleotides 2023 ·Nucleic Acid Therapeutics ·Jiaxin Hu, Xin Gong, Fan Yan, (unknown), Frank Rigo, (unknown), David R. Corey, V. Vinod Mootha	7
7	Long-Term SMN- and Ncald-ASO Combinatorial Therapy in SMA Mice and NCALD-ASO Treatment in hiPSC-Derived Motor Neurons Show Protective Effects 2023 ·International Journal of Molecular Sciences ·(unknown), (unknown), Karen Ling, (unknown), Frank Rigo, C. Frank Bennett, Brunhilde Wirth	7
8	ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth 2021 ·Cancer Research ·Wai Kit, (unknown), Juergen Scharner, Ana S.H. Costa, Kuan‐Ting Lin, Hyun Yong Jeon, John E. Wilkinson, Michaela Jackson, Frank Rigo, C. Frank Bennett, Adrian R. Krainer	79
9	Antisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment 2021 ·Science Translational Medicine ·Tracy L. Hagemann, Berit Powers, (unknown), Ahmed F. Mohamed, (unknown), (unknown), (unknown), Curt Mazur, Frank Rigo, Abby L. Olsen, Mel Β. Feany, Ming‐Der Perng, Robert F. Berman, Albee Messing	31
10	Sarm1 haploinsufficiency or low expression levels after antisense oligonucleotides delay programmed axon degeneration 2021 ·Cell Reports ·(unknown), Jonathan Gilley, Karen Ling, Paymaan Jafar‐Nejad, Frank Rigo, Michael P. Coleman	22
11	PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR 2021 ·eLife ·Allen T. Yu, Carmen Berasain, Sonam Bhatia, Keith Rivera, Bodu Liu, Frank Rigo, Darryl Pappin, David L. Spector	17
12	The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration 2020 ·Nucleic Acids Research ·Paymaan Jafar‐Nejad, Berit Powers, Armand Soriano, Hien Zhao, Daniel A. Norris, John Matson, (unknown), (unknown), (unknown), Seung Chun, Curt Mazur, Holly Kordasiewicz, Eric E. Swayze, Frank Rigo	62
13	Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction 2020 ·Nucleic Acids Research ·Lingyan Wang, J. Beth Kempton, Han Jiang, Francine M. Jodelka, (unknown), Rachel A. Dumont, Frank Rigo, Jennifer J Lentz, Michelle L. Hastings, John V. Brigande	27
14	Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease 2020 ·Nature Medicine ·(unknown), Francine M. Jodelka, Anthony J. Hinrich, Tyler B. Johnson, Joseph Ochaba, Michaela Jackson, Dominik M. Duelli, Jill M. Weimer, Frank Rigo, Michelle L. Hastings	34
15	A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis 2020 ·Nature Neuroscience ·Caitlin M. Rodriguez, (unknown), Michael G. Kearse, Jill M. Haenfler, Brittany N. Flores, Yu Liu, Marius F. Ifrim, M. Rebecca Glineburg, Amy Krans, Paymaan Jafar‐Nejad, Michael A. Sutton, Gary J. Bassell, Jack M. Parent, Frank Rigo, Sami J. Barmada, Peter K. Todd	46
16	Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice 2018 ·Neurobiology of Disease ·Krista J. Spiller, Tahiyana Khan, Myrna A. Dominique, Clark R. Restrepo, (unknown), (unknown), Paymaan Jafar‐Nejad, Bin Zhang, Armand Soriano, Frank Rigo, John Q. Trojanowski, Virginia M.‐Y. Lee	29
17	Strand-specific antisense oligonucleotides for C9ORF72-ALS/FTD (S25.004) 2018 ·Neurology ·Lindsey R. Hayes, Alyssa N. Coyne, Paymaan Jafar‐Nejad, Frank Rigo, Jeffrey Rothstein	1
18	SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage 2017 ·Proceedings of the National Academy of Sciences ·Mohini Jangi, Christina Fleet, Patrick Cullen, (unknown), Shila Mekhoubad, Eric Chiao, Norm Allaire, C. Frank Bennett, Frank Rigo, Adrian R. Krainer, Jessica A. Hurt, John P. Carulli, John F. Staropoli	91
19	Antisense Reduction of Tau in Adult Mice Protects against Seizures 2013 ·Journal of Neuroscience ·Sarah L. DeVos, (unknown), Guojun Chen, (unknown), Kaoru Yamada, Floy R. Stewart, Dorothy R. Schuler, Susan E. Maloney, David F. Wozniak, Frank Rigo, C. Frank Bennett, John R. Cirrito, David M. Holtzman, Timothy M. Miller	250
20	Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model breakdown → 2011 ·Nature ·Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung, Guy Horev, C. Frank Bennett, Adrian R. Krainer	556

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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