Han Seok Ko

15.1k citations

58 papers · 8.5k indexed · 4 hit papers · h-index 33

Impact in

Neurology top 0.1%
- Parkinson's Disease Mechanisms and Treatments
- Neurological diseases and metabolism
Cellular and Molecular Neuroscience top 0.5%
- Nuclear Receptors and Signaling

Papers in

Neurology 36
- Parkinson's Disease Mechanisms and Treatments 35
Cellular and Molecular Neuroscience 19
- Nuclear Receptors and Signaling 10
- Nerve injury and regeneration 5

Co-authors: Ted M. Dawson Valina L. Dawson Yunjong Lee Senthilkumar S. Karuppagounder Joo‐Ho Shin Yun-Il Lee Ho Chul Kang Olga Pletniková
Journals: Proceedings of the National Academy of Sciences (8 papers)Human Molecular Genetics (4 papers)Cells (3 papers)Journal of Biological Chemistry (3 papers)Acta Neuropathologica Communications (2 papers)
Partner nations: United States South Korea Czechia

In The Last Decade

Han Seok Ko

55 papers receiving 8.4k citations

Hit Papers

align trajectories log scale

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease 2019 · 961 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Neuron
2011 Cell
2010 Neuron
2009 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Han Seok Ko

Since Specialization

Citations

This map shows the geographic impact of Han Seok Ko's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Han Seok Ko with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Han Seok Ko more than expected).

Fields of papers citing papers by Han Seok Ko

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Han Seok Ko. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Han Seok Ko. The network helps show where Han Seok Ko may publish in the future.

Co-authors

The 25 scholars most cited alongside Han Seok Ko, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Han Seok Ko Line = papers co-authored together Han Seok Ko links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Polymeric nanoparticle-mediated GBA1 gene therapy is neuroprotective in a preclinical model of Parkinson’s disease Drug Delivery and Translational Research ·Mohit Kwatra, Gijung Kwak, Haolin Li, (unknown), Han Seok Ko	2025	0
2	Gba1 E326K renders motor and non-motor symptoms with pathological α-synuclein, tau and glial activation Brain ·Sin Ho Kweon, Hye Guk Ryu, Seung‐Hwan Kwon, Hyeonwoo Park, Saebom Lee, Nam-Shik Kim, Shi‐Xun Ma, Hee-Jung Jee, Sangjune Kim, Han Seok Ko	2024	5
3	Levodopa-Induced Dyskinesia in Parkinson’s Disease: Pathogenesis and Emerging Treatment Strategies Cells ·Destany K. Kwon, Mohit Kwatra, Jing Wang, Han Seok Ko	2022	76
4	Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease Acta Neuropathologica Communications ·Jong Sung Park, Tae‐In Kam, Saebom Lee, Hyejin Park, Yumin Oh, Seung‐Hwan Kwon, Jae‐Jin Song, Donghoon Kim, Hyunhee Kim, Aanishaa Jhaldiyal, Dong Hee Na, Kang Choon Lee, Eun Ji Park, Martin G. Pomper, Olga Pletniková, Juan C. Troncoso, Han Seok Ko, Valina L. Dawson, Ted M. Dawson, Seulki Lee	2021	134
5	Amyloid-like oligomerization of AIMP2 contributes to α-synuclein interaction and Lewy-like inclusion Science Translational Medicine ·Sangwoo Ham, Seung Pil Yun, Hyojung Kim, Donghoon Kim, Bo Am Seo, Heejeong Kim, Jeong‐Yong Shin, Mohammad Aasif Dar, Gum Hwa Lee, Yun Il Lee, Yun Il Lee, Doyeun Kim, Sung‐Hoon Kim, Hee-Seok Kweon, Joo‐Ho Shin, Han Seok Ko, Yunjong Lee	2020	25
6	Large and Externally Positioned Ligand-Coated Nanopatches Facilitate the Adhesion-Dependent Regenerative Polarization of Host Macrophages Nano Letters ·Sunhong Min, Yoo Sang Jeon, Hyojun Choi, Chandra Khatua, Na Li, Gunhyu Bae, Hee Joon Jung, Yuri Kim, Hyunsik Hong, Jeongeun Shin, Min Jun Ko, Han Seok Ko, Taesoon Kim, Jun Hwan Moon, Jae‐Jun Song, Vinayak P. Dravid, (unknown), (unknown), Heemin Kang	2020	24
7	Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease Neuron ·Sangjune Kim, Seung‐Hwan Kwon, Tae‐In Kam, Nikhil Panicker, Senthilkumar S. Karuppagounder, Saebom Lee, Jun Hee Lee, Richard W. Kim, Minjee Kook, Catherine A. Foss, Chen‐Tian Shen, Hojae Lee, Subhash Kulkarni, Pankaj J. Pasricha, Gabsang Lee, Martin G. Pomper, Valina L. Dawson, Ted M. Dawson, Han Seok Ko Hit paper breakdown →	2019	961
8	α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism Molecular Neurodegeneration ·Seung Pil Yun, Donghoon Kim, Sangjune Kim, Sang‐Min Kim, Senthilkumar S. Karuppagounder, Seung‐Hwan Kwon, Saebom Lee, Tae‐In Kam, Su-Hyun Lee, Sangwoo Ham, Jae Hong Park, Valina L. Dawson, Ted M. Dawson, Yunjong Lee, Han Seok Ko	2018	105
9	Overexpression of Parkinson’s Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology eNeuro ·Yulan Xiong, Stewart Neifert, Senthilkumar S. Karuppagounder, Jeannette N. Stankowski, Byoung Dae Lee, Jonathan C. Grima, Guanxing Chen, Han Seok Ko, Yunjong Lee, Debbie Swing, Lino Tessarollo, Ted M. Dawson, Valina L. Dawson	2017	25
10	VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2 Cell Death and Disease ·Seung Pil Yun, Hyojung Kim, Sangwoo Ham, Seung‐Hwan Kwon, Gum Hwa Lee, Joo‐Ho Shin, Sang Hun Lee, Han Seok Ko, Yunjong Lee	2017	23
11	The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease Scientific Reports ·Senthilkumar S. Karuppagounder, Saurav Brahmachari, Yunjong Lee, Valina L. Dawson, Ted M. Dawson, Han Seok Ko	2014	187
12	S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease Proceedings of the National Academy of Sciences ·Anthony H. Tsang, Yun-IL Lee, Han Seok Ko, Joseph M. Savitt, Olga Pletniková, Juan C. Troncoso, Valina L. Dawson, Ted M. Dawson, Kenny K. K. Chung	2009	125
13	PINK1-dependent recruitment of Parkin to mitochondria in mitophagy Proceedings of the National Academy of Sciences ·Cristòfol Vives-Bauzá, Chun Hui Zhou, Yong Huang, Mei Cui, Rosa L.A. de Vries, Jiho Kim, Jessica May, Maja A. Tocilescu, Wencheng Liu, Han Seok Ko, Jordi Magrané, Darren J. Moore, Valina L. Dawson, Régis Grailhe, Ted M. Dawson, Chenjian Li, Kim Tieu, Serge Przedborski Hit paper breakdown →	2009	1321
14	Role of Tuberin in Neuronal Degeneration Neurochemical Research ·Samy L. Habib, D Michel, Eliezer Masliah, Bobby Thomas, Han Seok Ko, Ted M. Dawson, Hanna E. Abboud, Robert A. Clark, Syed Z. Imam	2008	10
15	Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases Human Molecular Genetics ·Jeanne M.M. Tan, Esther Wong, Donald S. Kirkpatrick, Olga Pletniková, Han Seok Ko, Shiam-Peng Tay, Michelle W. L. Ho, Juan C. Troncoso, Steven P. Gygi, Michael K. Lee, Valina L. Dawson, Ted M. Dawson, Kah‐Leong Lim	2007	353
16	Identification of Far Upstream Element-binding Protein-1 as an Authentic Parkin Substrate Journal of Biological Chemistry ·Han Seok Ko, Seong Who Kim, Sathya R. Sriram, Valina L. Dawson, Ted M. Dawson	2006	83
17	Accumulation of the Authentic Parkin Substrate Aminoacyl-tRNA Synthetase Cofactor, p38/JTV-1, Leads to Catecholaminergic Cell Death Journal of Neuroscience ·Han Seok Ko, Rainer von Coelln, Sathya R. Sriram, Seong Who Kim, Kenny K. K. Chung, Olga Pletniková, Juan C. Troncoso, B. Lamar Johnson, Roya Saffary, Eyleen L. K. Goh, Hongjun Song, Bum-Joon Park, Min Jung Kim, Sung‐Hoon Kim, Valina L. Dawson, Ted M. Dawson	2005	202
18	Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function Human Molecular Genetics ·Cheng Wang, Han Seok Ko, Bobby Thomas, Fai Tsang, Katherine C. M. Chew, Shiam-Peng Tay, Michelle W. L. Ho, T. M. Lim, Tuck-Wah Soong, Olga Pletniková, Juan C. Troncoso, Valina L. Dawson, Ted M. Dawson, Kah‐Leong Lim	2005	169
19	Role of Ubiquilin Associated with Protein-disulfide Isomerase in the Endoplasmic Reticulum in Stress-induced Apoptotic Cell Death Journal of Biological Chemistry ·Han Seok Ko, Takashi Uehara, Yasuyuki Nomura	2002	138
20	The association of the percentage change of bone mineral density and bone markers after one year of hormone replacement therapy in postmenopausal women. Gajeong yihag hoeji ·Choi Jt, Seho Oh, Woo Ji, Han Seok Ko, I. K. Han	1999	1

About Han Seok Ko

Han Seok Ko is a scholar working on Neurology, Cellular and Molecular Neuroscience, Cell Biology, Physiology and Developmental Neuroscience, having authored 58 papers that have together received 8.5k indexed citations. Recurring topics across this work include Parkinson's Disease Mechanisms and Treatments (35 papers), Lysosomal Storage Disorders Research (10 papers), Nuclear Receptors and Signaling (10 papers), Autophagy in Disease and Therapy (9 papers), Alzheimer's disease research and treatments (8 papers), Cellular transport and secretion (6 papers), Nerve injury and regeneration (5 papers) and Endoplasmic Reticulum Stress and Disease (5 papers). The work is most often cited by research in Neurology (4.2k citations), Neurology (1.1k citations), Cellular and Molecular Neuroscience (2.2k citations), Physiology (2.0k citations) and Biological Psychiatry (158 citations). Han Seok Ko has collaborated with scholars based in United States, South Korea and Czechia. Frequent co-authors include Ted M. Dawson, Valina L. Dawson, Yunjong Lee, Senthilkumar S. Karuppagounder, Joo‐Ho Shin, Yun-Il Lee, Ho Chul Kang, Olga Pletniková, Juan C. Troncoso and Serge Przedborski. Their work appears in journals such as Proceedings of the National Academy of Sciences, Human Molecular Genetics, Cells, Journal of Biological Chemistry and Acta Neuropathologica Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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