Darren J. Moore

20.6k citations

86 papers · 10.2k indexed · 4 hit papers · h-index 49

Neurology top 0.05%
- Parkinson's Disease Mechanisms and Treatments 74
- Neurological diseases and metabolism 26
- Neurological disorders and treatments 13
- Botulinum Toxin and Related Neurological Disorders 6
Neurology top 0.2%
- Parkinson's Disease Mechanisms and Treatments 74
- Neurological diseases and metabolism 26
- Neurological disorders and treatments 13
- Botulinum Toxin and Related Neurological Disorders 6
Cellular and Molecular Neuroscience top 0.5%
- Nuclear Receptors and Signaling 11
Physiology top 0.2%
- Alzheimer's disease research and treatments 16
- Lysosomal Storage Disorders Research 12
Cell Biology top 0.5%
- Cellular transport and secretion 18

Co-authors: Ted M. Dawson Valina L. Dawson Andrew B. West Saskia Biskup Elpida Tsika Christopher A. Ross Wanli W. Smith Liliane Glauser
Cited by: Neurology Cellular and Molecular Neuroscience
Journals: Human Molecular Genetics (13 papers)Neurobiology of Disease (10 papers)Proceedings of the National Academy of Sciences (6 papers)
Partner nations: United States Switzerland United Kingdom

In The Last Decade

Darren J. Moore

86 papers receiving 10.1k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2012 Journal of Biological Chemistry
2009 Proceedings of the National Academy of Sciences
2005 Proceedings of the National Academy of Sciences
2005 Annual Review of Neuroscience

Peers

Countries citing papers authored by Darren J. Moore

Since Specialization

Citations

This map shows the geographic impact of Darren J. Moore's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darren J. Moore with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darren J. Moore more than expected).

Fields of papers citing papers by Darren J. Moore

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darren J. Moore. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darren J. Moore. The network helps show where Darren J. Moore may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Darren J. Moore, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Darren J. Moore Line = papers co-authored together Darren J. Moore links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation Molecular Neurodegeneration ·Jiangtao Liu,Xuying Yang,橋本純一,Jing Wang,Ravindra Boddu,Samuel Strader,Ivan Veršić,Nicole Bryant,Talene A. Yacoubian,David G. Standaert,بهرام احمدی,Darren J. Moore,Laurie H. Sanders,Michael W. Lutz,Dmitry Velmeshev,Andrew B. West	2024	7
2	Defining the Riddle in Order to Solve It: There Is More Than One “Parkinson's Disease” Movement Disorders ·Tiago F. Outeiro,Roy N. Alcalay,Angelo Antonini,Johannes Attems,Vincenzo Bonifati,Francisco Cardoso,Marie‐Françoise Chesselet,John Hardy,Graziella Madeo,Ian G. McKeith,Brit Mollenhauer,Darren J. Moore,Olivier Rascol,Michael G. Schlossmacher,Hermona Soreq,Leonidas Stefanis,Joaquim J. Ferreira	2023	20
3	Evaluation of Current Methods to Detect Cellular Leucine-Rich Repeat Kinase 2 (LRRK2) Kinase Activity Journal of Parkinson s Disease ·Belén Fernández,Dietlinde Warth,Jillian H. Kluss,Kaela Kelly,Nicole Bryant,Zepeng Sun,Syed Bukhari,Kohki HANAMURA,Antonio Jesús Lara Ordóñez,Elena Fdez,Marie‐Christine Chartier‐Harlin,Thomas J. Montine,Mark A. Wilson,Darren J. Moore,Andrew B. West,Mark Cookson,R. Jeremy Nichols,Sabine Hilfiker	2022	10
4	Multiple genetic pathways regulating lifespan extension are neuroprotective in a G2019S LRRK2 nematode model of Parkinson's disease Neurobiology of Disease ·Megan M. Senchuk,Jeremy M. Van Raamsdonk,Darren J. Moore	2021	11
5	Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity Proceedings of the National Academy of Sciences ·Zepeng Sun,Elpida Tsika,Kaela Kelly,Nathan Levine,Xi Chen,Andrew B. West,Sylviane Boularand,Pascal Barnéoud,Darren J. Moore	2020	43
6	LRRK2 and the Endolysosomal System in Parkinson’s Disease Journal of Parkinson s Disease ·أحمد محمد,Darren J. Moore	2020	67
7	Parkinson’s disease-linked D620N VPS35 knockin mice manifest tau neuropathology and dopaminergic neurodegeneration Proceedings of the National Academy of Sciences ·Xi Chen,Kong Jie-hua,Erin T. Williams,Nathan Levine,Allyson Cole-Strauss,Lee Marshall,Viviane Labrie,Jiyan Ma,Jack W. Lipton,Darren J. Moore	2019	75
8	VPS35, the Retromer Complex and Parkinson’s Disease Journal of Parkinson s Disease ·Erin T. Williams,Xi Chen,Darren J. Moore	2017	120
9	Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration Human Molecular Genetics ·Elpida Tsika,Liliane Glauser,Ralf Moser,Mueez K. Qureshi,Guillaume Daniel,Una‐Marie Sheerin,Andrew J. Lees,Juan C. Troncoso,Patrick A. Lewis,Rina Bandopadhyay,Bernard L. Schneider,Darren J. Moore	2014	117
10	Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily Human Molecular Genetics ·Klodjan Stafa,Elpida Tsika,Roger Moser,Alessandra Musso,Liliane Glauser,Amy Jones,Saskia Biskup,Yulan Xiong,Rina Bandopadhyay,Valina L. Dawson,Ted M. Dawson,Darren J. Moore	2013	106
11	Contribution of GTPase activity toLRRK2-associated Parkinson disease Small GTPases ·Elpida Tsika,Darren J. Moore	2013	44
12	Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1 Journal of Neurochemistry ·Liliane Glauser,Sarah Sonnay,Klodjan Stafa,Darren J. Moore	2011	193
13	PINK1-dependent recruitment of Parkin to mitochondria in mitophagybreakdown → Proceedings of the National Academy of Sciences ·Cristòfol Vives-Bauzá,Chun Hui Zhou,Yong Huang,Mei Cui,C Sarno,Jiho Kim,尹小波,Maja A. Tocilescu,Wencheng Liu,Han Seok Ko,Jordi Magrané,Darren J. Moore,Valina L. Dawson,Régis Grailhe,Ted M. Dawson,Chenjian Li,Kim Tieu,Serge Przedborski	2009	1321
14	Abnormal Localization of Leucine-Rich Repeat Kinase 2 to the Endosomal-Lysosomal Compartment in Lewy Body Disease Journal of Neuropathology & Experimental Neurology ·Shinji Higashi,Darren J. Moore,Ryoko Yamamoto,Michiko Minegishi,Kiyoshi Sato,Takashi Togo,Omi Katsuse,Hirotake Uchikado,Yoshiko Furukawa,Hiroaki Hino,Kenji Kosaka,Piers C. Emson,Keiji Wada,Valina L. Dawson,Ted M. Dawson,Heii Arai,Eizo Iseki	2009	67
15	Conditional transgenic mice expressing C-terminally truncated human α-synuclein (αSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons Molecular Neurodegeneration ·João Paulo Lima Daher,Mingyao Ying,Rebecca Banerjee,Salim Benhamadi,Utku Kucuker,Lichuan Yang,M. Flint Beal,Bobby Thomas,Valina L. Dawson,Ted M. Dawson,Darren J. Moore	2009	73
16	The Chaperone Activity of Heat Shock Protein 90 Is Critical for Maintaining the Stability of Leucine-Rich Repeat Kinase 2 Journal of Neuroscience ·Lizhen Wang,Chengsong Xie,Elisa Greggio,Loukia Parisiadou,Hoon Shim,Lixin Sun,Jayanth Chandran,Xian Lin,Chen Lai,霍蓉,Darren J. Moore,Ted M. Dawson,Valina L. Dawson,Gabriela Chiosis,Mark Cookson,Huaibin Cai	2008	156
17	Detrimental deletions: mitochondria, aging and Parkinson's disease BioEssays ·Saskia Biskup,Darren J. Moore	2006	28
18	GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge: possible role in neuroimmune function Molecular Brain Research ·Darren J. Moore,Paul R. Murdock,Jeannette M. Watson,Richard L. M. Faull,Henry J. Waldvogel,Philip Szekeres,Shelagh Wilson,Katie B. Freeman,Piers C. Emson	2003	85
19	A missense mutation (L166P) in DJ‐1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo‐oligomerization Journal of Neurochemistry ·Darren J. Moore,Li Zhang,Ted M. Dawson,Valina L. Dawson	2003	186
20	Regional and cellular distribution of the P2Y1 purinergic receptor in the human brain: Striking neuronal localisation The Journal of Comparative Neurology ·Darren J. Moore,Jon Chambers,Henry J. Waldvogel,Richard L. M. Faull,Piers C. Emson	2000	126

About Darren J. Moore

Darren J. Moore is a scholar working on Neurology, Neurology and Cell Biology, having authored 86 papers that have together received 10.2k indexed citations. Recurring topics across this work include Parkinson's Disease Mechanisms and Treatments (74 papers), Neurological diseases and metabolism (26 papers), Cellular transport and secretion (18 papers), Alzheimer's disease research and treatments (16 papers), Neurological disorders and treatments (13 papers), Lysosomal Storage Disorders Research (12 papers), Nuclear Receptors and Signaling (11 papers) and Botulinum Toxin and Related Neurological Disorders (6 papers). The work is most often cited by research in Neurology (6.8k citations), Neurology (1.9k citations) and Cellular and Molecular Neuroscience (2.8k citations). Darren J. Moore has collaborated with scholars based in United States, Switzerland and United Kingdom. Frequent co-authors include Ted M. Dawson, Valina L. Dawson, Andrew B. West, Saskia Biskup, Elpida Tsika, Christopher A. Ross, Wanli W. Smith, Liliane Glauser, Piers C. Emson and Artem Bugayenko. Their work appears in journals such as Human Molecular Genetics, Neurobiology of Disease, Proceedings of the National Academy of Sciences, Journal of Neurochemistry and Journal of Parkinson s Disease.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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