Juan C. Troncoso

56.6k total citations · 11 hit papers
318 papers, 26.0k citations indexed

About

Juan C. Troncoso is a scholar working on Physiology, Neurology and Molecular Biology. According to data from OpenAlex, Juan C. Troncoso has authored 318 papers receiving a total of 26.0k indexed citations (citations by other indexed papers that have themselves been cited), including 126 papers in Physiology, 107 papers in Neurology and 96 papers in Molecular Biology. Recurrent topics in Juan C. Troncoso's work include Alzheimer's disease research and treatments (124 papers), Parkinson's Disease Mechanisms and Treatments (63 papers) and Dementia and Cognitive Impairment Research (46 papers). Juan C. Troncoso is often cited by papers focused on Alzheimer's disease research and treatments (124 papers), Parkinson's Disease Mechanisms and Treatments (63 papers) and Dementia and Cognitive Impairment Research (46 papers). Juan C. Troncoso collaborates with scholars based in United States, Germany and United Kingdom. Juan C. Troncoso's co-authors include Olga Pletniková, Ted M. Dawson, Claudia H. Kawas, Valina L. Dawson, Donald L. Price, Richard O’Brien, Susan M. Resnick, Gay Rudow, Michael K. Lee and Walter F. Stewart and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Juan C. Troncoso

311 papers receiving 25.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

2004 905 citations Juan C. Troncoso et al. Proceedings of the National Academy of Sciences profile →
Interference by Huntingtin and Atrophin-1 with CBP-Mediated Transcription Leading to Cellular Toxicity

2001 880 citations Juan C. Troncoso, Valina L. Dawson et al. Science profile →
C9orf72 nucleotide repeat structures initiate molecular cascades of disease

2014 730 citations Juan C. Troncoso et al. profile →
Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome

2000 669 citations Juan C. Troncoso et al. profile →
S -Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function

2004 636 citations Kenny K. K. Chung, Bobby Thomas et al. Science profile →
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia

2013 577 citations Tao Zu, Mónica Báñez-Coronel et al. Proceedings of the National Academy of Sciences profile →
Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

2010 536 citations Juan C. Troncoso et al. profile →
TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD

2015 387 citations Jonathan P. Ling, Olga Pletniková et al. Science profile →
Evidence for brain glucose dysregulation in Alzheimer's disease

2017 360 citations Yang An, Vijay R. Varma et al. profile →
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease

2022 139 citations Nikhil Panicker, Hu Wang et al. profile →
A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS–FTD

2024 52 citations Koping Chang, Juan C. Troncoso et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Juan C. Troncoso United States	87	11.3k	9.5k	7.3k	6.6k	4.0k	318	26.0k
Peter St George‐Hyslop Canada	83	12.1k 1.1×	16.8k 1.8×	4.7k 0.6×	5.3k 0.8×	3.7k 0.9×	391	28.3k
Edward Rockenstein United States	76	7.9k 0.7×	10.3k 1.1×	9.7k 1.3×	8.6k 1.3×	5.2k 1.3×	195	24.4k
Hitoshi Takahashi Japan	87	10.3k 0.9×	5.0k 0.5×	13.6k 1.9×	9.6k 1.5×	4.1k 1.0×	736	30.3k
Isidró Ferrer Spain	101	20.4k 1.8×	12.8k 1.4×	8.3k 1.1×	11.4k 1.7×	7.7k 1.9×	910	42.1k
Jeffery M. Vance United States	70	12.8k 1.1×	10.3k 1.1×	4.2k 0.6×	7.0k 1.1×	3.6k 0.9×	298	29.0k
Charles Duyckaerts France	72	6.6k 0.6×	9.5k 1.0×	6.6k 0.9×	5.5k 0.8×	4.6k 1.1×	287	21.6k
Ryōsuke Takahashi Japan	68	10.9k 1.0×	3.8k 0.4×	7.3k 1.0×	4.9k 0.7×	3.7k 0.9×	622	23.5k
Michael A. Moskowitz United States	94	12.8k 1.1×	7.7k 0.8×	4.4k 0.6×	7.6k 1.1×	8.6k 2.1×	230	35.7k
Matthew P. Frosch United States	86	9.4k 0.8×	16.8k 1.8×	8.3k 1.1×	6.4k 1.0×	6.5k 1.6×	299	32.3k
Gen Sobue Japan	82	12.4k 1.1×	4.2k 0.4×	11.6k 1.6×	9.6k 1.5×	2.9k 0.7×	754	28.1k

Countries citing papers authored by Juan C. Troncoso

Since Specialization

Citations

This map shows the geographic impact of Juan C. Troncoso's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Juan C. Troncoso with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Juan C. Troncoso more than expected).

Fields of papers citing papers by Juan C. Troncoso

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Juan C. Troncoso. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Juan C. Troncoso. The network helps show where Juan C. Troncoso may publish in the future.

Co-authorship network of co-authors of Juan C. Troncoso

This figure shows the co-authorship network connecting the top 25 collaborators of Juan C. Troncoso. A scholar is included among the top collaborators of Juan C. Troncoso based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Juan C. Troncoso. Juan C. Troncoso is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Stein-O’Brien, Genevieve, E. Michael Meyer, Javier Redding‐Ochoa, et al.. (2025). Transcriptional signatures of hippocampal tau pathology in primary age-related tauopathy and Alzheimer’s disease. Cell Reports. 44(3). 115422–115422. 1 indexed citations

Gurfinkel, Enrique, Carlos Vigliano, Patricia Cabeza Meckert, et al.. (2025). Presencia de placas coronarias vulnerables en mujeres de mediana edad que sufrieron muerte cerebral. Revista Argentina de Cardiología. 77(6). 478–486.

Katsumata, Yuriko, David W. Fardo, Davis C. Woodworth, et al.. (2024). Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer’s pathologies. Acta Neuropathologica. 148(1). 66–66. 5 indexed citations

Khan, Mohammed Repon, Xiling Yin, Sung-Ung Kang, et al.. (2023). Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson’s disease. Science Translational Medicine. 15(724). eadd0499–eadd0499. 29 indexed citations

Pirooznia, Sheila K., Hu Wang, Nikhil Panicker, et al.. (2022). Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson’s disease. Science Advances. 8(13). eabh1824–eabh1824. 21 indexed citations

Hinkle, Jared T., Jaimin Patel, Nikhil Panicker, et al.. (2022). STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy. Proceedings of the National Academy of Sciences. 119(15). e2118819119–e2118819119. 138 indexed citations

Huang, Yiyao, Lesley Cheng, Andrey Turchinovich, et al.. (2020). Influence of species and processing parameters on recovery and content of brain tissue‐derived extracellular vesicles. Journal of Extracellular Vesicles. 9(1). 1785746–1785746. 86 indexed citations

Mahajan, Uma V., Vijay R. Varma, Michael Griswold, et al.. (2020). Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study. PLoS Medicine. 17(1). e1003012–e1003012. 112 indexed citations

Ayhan, Fatma, B. Pérez, Hannah K. Shorrock, et al.. (2018). SCA 8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF 3F. The EMBO Journal. 37(19). 47 indexed citations

10.

Xiao, Mei-Fang, Desheng Xu, Michael T. Craig, et al.. (2017). NPTX2 and cognitive dysfunction in Alzheimer’s Disease. eLife. 6. 236 indexed citations

11.

Ling, Jonathan P., Olga Pletniková, Juan C. Troncoso, & Philip C. Wong. (2015). TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD. Science. 349(6248). 650–655. 387 indexed citations breakdown →

12.

Colla, Emanuela, Philippe Coune, Ying Liu, et al.. (2012). Endoplasmic Reticulum Stress Is Important for the Manifestations of α-SynucleinopathyIn Vivo. Journal of Neuroscience. 32(10). 3306–3320. 315 indexed citations

13.

Kramer, Patricia L., Haiyan Xu, Randall L. Woltjer, et al.. (2010). Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study. Neurobiology of Aging. 32(12). 2113–2122. 82 indexed citations

14.

Liu, Zhong Wu, Ying Liang, Naoki Masuda, et al.. (2010). Synphilin-1 attenuates neuronal degeneration in the A53T -synuclein transgenic mouse model. Human Molecular Genetics. 19(11). 2087–2098. 57 indexed citations

15.

Tsang, Anthony H., Han Seok Ko, Joseph M. Savitt, et al.. (2009). S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease. Proceedings of the National Academy of Sciences. 106(12). 4900–4905. 125 indexed citations

16.

Ko, Han Seok, Rainer von Coelln, Seong Who Kim, et al.. (2005). Accumulation of the Authentic Parkin Substrate Aminoacyl-tRNA Synthetase Cofactor, p38/JTV-1, Leads to Catecholaminergic Cell Death. Journal of Neuroscience. 25(35). 7968–7978. 202 indexed citations

17.

Wang, Cheng, Han Seok Ko, Bobby Thomas, et al.. (2005). Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function. Human Molecular Genetics. 14(24). 3885–3897. 169 indexed citations

18.

Bouffard, John‐Paul, Hernando Mena, Mary Ripple, & Juan C. Troncoso. (2003). Mesencephalic cryptococcal abscesses presenting with parkinsonism as an initial manifestation of AIDS. Movement Disorders. 18(11). 1354–1357. 8 indexed citations

19.

Borchelt, David, Donald L. Price, Diane B. McCarthy, et al.. (2001). β -Amyloid Peptide Vaccination Results in Marked Changes in Serum and Brain A β Levels in APPswe/PS1ΔE9 Mice, as Detected by SELDI-TOF-Based ProteinChip ^® Technology. DNA and Cell Biology. 20(11). 713–721. 41 indexed citations

20.

Sze, Chun‐I, et al.. (1997). Loss of the Presynaptic Vesicle Protein Synaptophysin in Hippocampus Correlates with Cognitive Decline in Alzheimer Disease. Journal of Neuropathology & Experimental Neurology. 56(8). 933–944. 453 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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