Lorenzo Moretta

79.2k total citations · 16 hit papers
678 papers, 60.8k citations indexed

About

Lorenzo Moretta is a scholar working on Immunology, Oncology and Hematology. According to data from OpenAlex, Lorenzo Moretta has authored 678 papers receiving a total of 60.8k indexed citations (citations by other indexed papers that have themselves been cited), including 621 papers in Immunology, 149 papers in Oncology and 84 papers in Hematology. Recurrent topics in Lorenzo Moretta's work include Immune Cell Function and Interaction (529 papers), T-cell and B-cell Immunology (397 papers) and Immunotherapy and Immune Responses (110 papers). Lorenzo Moretta is often cited by papers focused on Immune Cell Function and Interaction (529 papers), T-cell and B-cell Immunology (397 papers) and Immunotherapy and Immune Responses (110 papers). Lorenzo Moretta collaborates with scholars based in Italy, United States and Switzerland. Lorenzo Moretta's co-authors include Alessandro Moretta, Maria Cristina Mingari, Cristina Bottino, Daniela Pende, Massimo Vitale, Roberto Biassoni, Vito Pistoia, Antonio Uccelli, Claudia Cantoni and Simona Sivori and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Lorenzo Moretta

669 papers receiving 58.9k citations

Hit Papers

Mesenchymal stem cells in hea... 1975 2026 1992 2009 2008 2001 1977 2007 2005 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mesenchymal stem cells in health and disease
    2008 2.9k citations Antonio Uccelli, Lorenzo Moretta et al. Nature reviews. Immunology profile →
  2. Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis
    2001 1.4k citations Alessandro Moretta, Cristina Bottino et al. profile →
  3. Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG.
    1977 1.0k citations Lorenzo Moretta, Carlo E. Grossi et al. The Journal of Experimental Medicine profile →
  4. Mesenchymal stem cells inhibit natural killer–cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2
    2007 886 citations Maria Cristina Mingari, Lorenzo Moretta et al. Blood profile →
  5. Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
    2005 835 citations Maria Cristina Mingari, Lorenzo Moretta et al. Blood profile →
  6. Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells
    2002 794 citations Guido Ferlazzo, Lorenzo Moretta et al. The Journal of Experimental Medicine profile →
  7. RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS
    1996 749 citations Alessandro Moretta, Cristina Bottino et al. profile →
  8. Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule
    2003 705 citations Cristina Bottino, Daniela Pende et al. The Journal of Experimental Medicine profile →
  9. Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells
    1999 611 citations Daniela Pende, Simona Sivori et al. The Journal of Experimental Medicine profile →
  10. NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis
    1998 590 citations Massimo Vitale, Cristina Bottino et al. The Journal of Experimental Medicine profile →
  11. Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells
    2003 574 citations Claudia Cantoni, Mariella Della Chiesa et al. Proceedings of the National Academy of Sciences profile →
  12. MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2
    2009 526 citations Lorenzo Moretta et al. Blood profile →
  13. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains
    1995 500 citations Claudia Cantoni, Massimo Vitale et al. profile →
  14. Human NK cells: surface receptors, inhibitory checkpoints, and translational applications
    2019 399 citations Simona Sivori, Paola Vacca et al. profile →
  15. Expression of a receptor for IgM by human T cells in vitro
    1975 387 citations Lorenzo Moretta, Maria Cristina Mingari et al. European Journal of Immunology profile →
  16. Subpopulations of Human T Cells Identified by Receptors for Immunoglobulins and Mitogen Responsiveness
    1976 374 citations Lorenzo Moretta, Maria Cristina Mingari et al. The Journal of Immunology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Lorenzo Moretta Italy 128 48.3k 14.2k 7.5k 6.8k 6.5k 678 60.8k
Bruce R. Blazar United States 119 36.0k 0.7× 16.5k 1.2× 9.4k 1.3× 20.2k 3.0× 5.0k 0.8× 843 58.3k
Jacques Banchereau United States 132 62.4k 1.3× 15.0k 1.1× 16.4k 2.2× 3.6k 0.5× 2.2k 0.3× 477 80.5k
Arlene H. Sharpe United States 130 47.7k 1.0× 28.8k 2.0× 16.3k 2.2× 3.5k 0.5× 2.3k 0.3× 408 75.8k
Lewis L. Lanier United States 147 60.8k 1.3× 14.1k 1.0× 10.0k 1.3× 5.2k 0.8× 1.2k 0.2× 470 72.2k
Michael A. Caligiuri United States 108 25.9k 0.5× 14.0k 1.0× 13.6k 1.8× 9.5k 1.4× 3.6k 0.6× 438 46.7k
Jerome Ritz United States 103 19.0k 0.4× 10.1k 0.7× 6.4k 0.8× 12.9k 1.9× 4.8k 0.7× 610 36.4k
Shimon Sakaguchi Japan 109 53.8k 1.1× 15.6k 1.1× 9.0k 1.2× 2.9k 0.4× 1.3k 0.2× 308 68.3k
Eugene C. Butcher United States 126 31.9k 0.7× 10.2k 0.7× 12.4k 1.7× 4.3k 0.6× 1.1k 0.2× 338 53.4k
Alain Fischer France 111 25.9k 0.5× 7.4k 0.5× 14.3k 1.9× 9.4k 1.4× 2.8k 0.4× 706 46.7k
Herman Waldmann United Kingdom 105 22.3k 0.5× 5.4k 0.4× 6.9k 0.9× 5.8k 0.9× 2.9k 0.4× 539 36.5k

Countries citing papers authored by Lorenzo Moretta

Since Specialization
Citations

This map shows the geographic impact of Lorenzo Moretta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lorenzo Moretta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lorenzo Moretta more than expected).

Fields of papers citing papers by Lorenzo Moretta

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lorenzo Moretta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lorenzo Moretta. The network helps show where Lorenzo Moretta may publish in the future.

Co-authorship network of co-authors of Lorenzo Moretta

This figure shows the co-authorship network connecting the top 25 collaborators of Lorenzo Moretta. A scholar is included among the top collaborators of Lorenzo Moretta based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lorenzo Moretta. Lorenzo Moretta is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Maggi, Enrico, Nadine Landolina, Enrico Munari, et al.. (2025). T cells in the microenvironment of solid pediatric tumors: the case of neuroblastoma. Frontiers in Immunology. 16. 1544137–1544137.
2.
Cantoni, Claudia, Michela Falco, Massimo Vitale, et al.. (2024). Human NK cells and cancer. OncoImmunology. 13(1). 2378520–2378520. 13 indexed citations
3.
Mariotti, Francesca Romana, Domenico Supino, Nadine Landolina, et al.. (2023). IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC. Seminars in Immunology. 66. 101712–101712. 11 indexed citations
4.
Landolina, Nadine, Francesca Romana Mariotti, Tiziano Ingegnere, et al.. (2022). IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells. Journal for ImmunoTherapy of Cancer. 10(3). e003858–e003858. 10 indexed citations
5.
Infante, Paola, Elisa Ferretti, Ombretta Melaiu, et al.. (2020). Nutlin-3a Enhances Natural Killer Cell–Mediated Killing of Neuroblastoma by Restoring p53-Dependent Expression of Ligands for NKG2D and DNAM-1 Receptors. Cancer Immunology Research. 9(2). 170–183. 34 indexed citations
6.
Cilloni, Daniela, Jessica Petiti, Marina Podestà, et al.. (2020). Transplantation Induces Profound Changes in the Transcriptional Asset of Hematopoietic Stem Cells: Identification of Specific Signatures Using Machine Learning Techniques. Journal of Clinical Medicine. 9(6). 1670–1670. 4 indexed citations
7.
Pesce, Silvia, Marco Greppi, Francesco Grossi, et al.. (2019). PD/1-PD-Ls Checkpoint: Insight on the Potential Role of NK Cells. Frontiers in Immunology. 10. 1242–1242. 137 indexed citations
8.
Ingegnere, Tiziano, Francesca Romana Mariotti, Andrea Pelosi, et al.. (2019). Human CAR-NK cells: A new non-viral method allowing high efficient transfection and target cell killing. 5. 1–1. 1 indexed citations
9.
Huergo-Zapico, Leticía, Monica Parodi, Claudia Cantoni, et al.. (2018). NK-cell Editing Mediates Epithelial-to-Mesenchymal Transition via Phenotypic and Proteomic Changes in Melanoma Cell Lines. Cancer Research. 78(14). 3913–3925. 59 indexed citations
10.
Bono, Marı́a Rosa, Daniela Pende, Alice Bertaina, et al.. (2018). Analysis of KIR3DP1 Polymorphism Provides Relevant Information on Centromeric KIR Gene Content. The Journal of Immunology. 201(5). 1460–1467. 5 indexed citations
11.
Saunders, Philippa M., Phillip Pymm, Gabriella Pietra, et al.. (2016). Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition. The Journal of Experimental Medicine. 213(5). 791–807. 63 indexed citations
12.
Pietra, Gabriella, Claudia Manzini, Silvia Rivara, et al.. (2012). Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity. Cancer Research. 72(6). 1407–1415. 249 indexed citations
13.
Vacca, Paola, Chiara Vitale, Elisa Montaldo, et al.. (2011). CD34 + hematopoietic precursors are present in human decidua and differentiate into natural killer cells upon interaction with stromal cells. Proceedings of the National Academy of Sciences. 108(6). 2402–2407. 181 indexed citations
14.
Sivori, Simona, Michela Falco, Simona Carlomagno, et al.. (2010). A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2. Blood. 116(10). 1637–1647. 73 indexed citations
15.
Bertaina, Alice, Franco Locatelli, & Lorenzo Moretta. (2009). Transplantation and innate immunity: the lesson of natural killer cells. ˜The œItalian Journal of Pediatrics/Italian journal of pediatrics. 35(1). 44–44. 6 indexed citations
16.
Uccelli, Antonio, Lorenzo Moretta, & Vito Pistoia. (2008). Mesenchymal stem cells in health and disease. Nature reviews. Immunology. 8(9). 726–736. 2859 indexed citations breakdown →
17.
Carrega, Paolo, Barbara Morandi, Roberta Costa, et al.. (2008). Natural killer cells infiltrating human nonsmall‐cell lung cancer are enriched in CD56brightCD16− cells and display an impaired capability to kill tumor cells. Cancer. 112(4). 863–875. 303 indexed citations
18.
Sivori, Simona, Michela Falco, Mariella Della Chiesa, et al.. (2004). CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: Induction of cytokine release and cytotoxicity against tumors and dendritic cells. Proceedings of the National Academy of Sciences. 101(27). 10116–10121. 368 indexed citations
19.
Bröker, Barbara M., Lorenzo Moretta, Ermanno Ciccone, et al.. (1990). Tγδ Cells and their Subsets in Blood and Synovial Tissue from Rheumatoid Arthritis Patients. Scandinavian Journal of Immunology. 32(6). 585–593. 60 indexed citations
20.
Moretta, Lorenzo, Daniela Pende, Cristina Bottino, et al.. (1987). Human CD3+4−8−WT31−T lymphocyte expressing the putative T cell receptor γ‐gene product. A limiting dilution and clonal analysis. European Journal of Immunology. 17(9). 1229–1234. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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