Jason M. Brenchley

37.4k total citations · 13 hit papers
184 papers, 26.6k citations indexed

About

Jason M. Brenchley is a scholar working on Virology, Immunology and Infectious Diseases. According to data from OpenAlex, Jason M. Brenchley has authored 184 papers receiving a total of 26.6k indexed citations (citations by other indexed papers that have themselves been cited), including 118 papers in Virology, 117 papers in Immunology and 57 papers in Infectious Diseases. Recurrent topics in Jason M. Brenchley's work include HIV Research and Treatment (117 papers), Immune Cell Function and Interaction (101 papers) and T-cell and B-cell Immunology (60 papers). Jason M. Brenchley is often cited by papers focused on HIV Research and Treatment (117 papers), Immune Cell Function and Interaction (101 papers) and T-cell and B-cell Immunology (60 papers). Jason M. Brenchley collaborates with scholars based in United States, United Kingdom and France. Jason M. Brenchley's co-authors include Daniel C. Douek, David A. Price, Richard A. Koup, Michael R. Betts, Mario Roederer, Timothy W. Schacker, Brenna J. Hill, Joseph P. Casazza, David R. Ambrozak and Guido Silvestri and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Jason M. Brenchley

181 papers receiving 26.3k citations

Hit Papers

Microbial translocation is a cause of systemic immune act... 2001 2026 2009 2017 2006 2004 2009 2003 2002 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    2006 2.7k citations Jason M. Brenchley, David A. Price et al. Nature Medicine profile →
  2. CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract
    2004 1.4k citations Jason M. Brenchley, Timothy W. Schacker et al. The Journal of Experimental Medicine profile →
  3. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
    2009 1.3k citations Jason M. Brenchley, Timothy W. Schacker et al. Nature Medicine profile →
  4. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
    2003 1.3k citations Michael R. Betts, Jason M. Brenchley et al. profile →
  5. HIV preferentially infects HIV-specific CD4+ T cells
    2002 982 citations Daniel C. Douek, Jason M. Brenchley et al. profile →
  6. Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection
    2011 856 citations Netanya G. Sandler, Handan Wand et al. The Journal of Infectious Diseases profile →
  7. Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
    2008 848 citations Jason M. Brenchley, Daniel C. Douek et al. profile →
  8. Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells
    2003 812 citations Jason M. Brenchley, Michael R. Betts et al. Blood profile →
  9. PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
    2006 725 citations Joseph P. Casazza, Jason M. Brenchley et al. The Journal of Experimental Medicine profile →
  10. Commensal–dendritic-cell interaction specifies a unique protective skin immune signature
    2014 603 citations Jason M. Brenchley, Yasmine Belkaid et al. profile →
  11. Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4 + and CD8 + T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection
    2001 574 citations Michael R. Betts, David R. Ambrozak et al. Journal of Virology profile →
  12. Relationship between T Cell Activation and CD4 + T Cell Count in HIV‐Seropositive Individuals with Undetectable Plasma HIV RNA Levels in the Absence of Therapy
    2007 506 citations Peter W. Hunt, Jason M. Brenchley et al. The Journal of Infectious Diseases profile →
  13. Plasma Levels of Bacterial DNA Correlate with Immune Activation and the Magnitude of Immune Restoration in Persons with Antiretroviral‐Treated HIV Infection
    2009 463 citations Wei Jiang, Michael M. Lederman et al. The Journal of Infectious Diseases profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jason M. Brenchley United States 72 14.8k 13.8k 7.7k 6.0k 4.1k 184 26.6k
Alan Landay United States 82 10.0k 0.7× 12.7k 0.9× 9.1k 1.2× 6.6k 1.1× 4.1k 1.0× 525 27.3k
Michael M. Lederman United States 78 8.4k 0.6× 13.1k 0.9× 9.8k 1.3× 6.4k 1.1× 3.2k 0.8× 381 24.7k
Joseph M. McCune United States 79 9.1k 0.6× 9.6k 0.7× 5.8k 0.8× 4.2k 0.7× 3.1k 0.7× 216 19.4k
Sharon R. Lewin Australia 67 5.8k 0.4× 9.9k 0.7× 8.0k 1.0× 6.6k 1.1× 2.3k 0.6× 370 19.0k
Giuseppe Pantaleo Switzerland 71 11.2k 0.8× 10.6k 0.8× 6.5k 0.8× 4.9k 0.8× 2.4k 0.6× 288 19.9k
Rafick‐Pierre Sékaly United States 70 12.1k 0.8× 8.8k 0.6× 4.6k 0.6× 3.5k 0.6× 3.4k 0.8× 310 19.1k
Daniel C. Douek United States 104 26.6k 1.8× 19.1k 1.4× 11.1k 1.4× 9.5k 1.6× 6.2k 1.5× 338 44.9k
Jan M. Orenstein United States 70 6.2k 0.4× 10.3k 0.7× 6.6k 0.9× 4.8k 0.8× 3.7k 0.9× 213 20.7k
Joseph B. Margolick United States 64 4.8k 0.3× 12.9k 0.9× 10.2k 1.3× 4.1k 0.7× 2.3k 0.6× 257 19.7k
Brigitte Autran France 65 7.2k 0.5× 8.5k 0.6× 5.8k 0.8× 4.5k 0.7× 1.6k 0.4× 307 15.8k

Countries citing papers authored by Jason M. Brenchley

Since Specialization
Citations

This map shows the geographic impact of Jason M. Brenchley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jason M. Brenchley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jason M. Brenchley more than expected).

Fields of papers citing papers by Jason M. Brenchley

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jason M. Brenchley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jason M. Brenchley. The network helps show where Jason M. Brenchley may publish in the future.

Co-authorship network of co-authors of Jason M. Brenchley

This figure shows the co-authorship network connecting the top 25 collaborators of Jason M. Brenchley. A scholar is included among the top collaborators of Jason M. Brenchley based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jason M. Brenchley. Jason M. Brenchley is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Davies, Jonathan P., Laura A. VanBlargan, Andrew R. Rahmberg, et al.. (2025). Oropouche virus efficiently replicates and is immunostimulatory in vivo in nonhuman primate species. Science Advances. 11(38). eadx9405–eadx9405.
2.
Košík, Ivan, Tiansheng Li, Victoria Callahan, et al.. (2024). Recombinant OC43 SARS-CoV-2 spike replacement virus: An improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays. Proceedings of the National Academy of Sciences. 121(29). e2310421121–e2310421121. 7 indexed citations
3.
Pandrea, Ivona, et al.. (2022). I’ve looked at gut from both sides now: Gastrointestinal tract involvement in the pathogenesis of SARS-CoV-2 and HIV/SIV infections. Frontiers in Immunology. 13. 899559–899559. 6 indexed citations
4.
Vujkovic-Cvijin, Ivan, Hugh C. Welles, Connie Ha, et al.. (2022). The systemic anti-microbiota IgG repertoire can identify gut bacteria that translocate across gut barrier surfaces. Science Translational Medicine. 14(658). eabl3927–eabl3927. 43 indexed citations
5.
Presti, Rachel M., Brett Williams, Alan Landay, et al.. (2021). A Randomized, Placebo-Controlled Trial Assessing the Effect of VISBIOME ES Probiotic in People With HIV on Antiretroviral Therapy. Open Forum Infectious Diseases. 8(12). ofab550–ofab550. 12 indexed citations
6.
Lewis, Michael D., Andrea Paun, Audrey Romano, et al.. (2020). Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophylaxis. PLoS Pathogens. 16(4). e1008456–e1008456. 17 indexed citations
7.
Sherrill-Mix, Scott, Grace M. Aldrovandi, Jason M. Brenchley, et al.. (2020). A Summary of the Fifth Annual Virology Education HIV Microbiome Workshop. AIDS Research and Human Retroviruses. 36(11). 886–895. 3 indexed citations
8.
Ortiz, Alexandra M., Jacob K. Flynn, Sarah R. DiNapoli, et al.. (2018). Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques. Nature Medicine. 24(9). 1313–1316. 28 indexed citations
9.
Pinacchio, Claudia, Maura Statzu, Letizia Santinelli, et al.. (2018). Type I/II Interferon in HIV-1-Infected Patients: Expression in Gut Mucosa and in Peripheral Blood Mononuclear Cells and Its Modification upon Probiotic Supplementation. Journal of Immunology Research. 2018. 1–7. 15 indexed citations
10.
Ceccarelli, Giancarlo, Jason M. Brenchley, Eugenio Nelson Cavallari, et al.. (2017). Impact of High-Dose Multi-Strain Probiotic Supplementation on Neurocognitive Performance and Central Nervous System Immune Activation of HIV-1 Infected Individuals. Nutrients. 9(11). 1269–1269. 41 indexed citations
11.
Canary, Lauren, Carol L. Vinton, David R. Morcock, et al.. (2013). Rate of AIDS Progression Is Associated with Gastrointestinal Dysfunction in Simian Immunodeficiency Virus–Infected Pigtail Macaques. The Journal of Immunology. 190(6). 2959–2965. 33 indexed citations
12.
Brenchley, Jason M., Carol L. Vinton, Brian Tabb, et al.. (2012). Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections. Blood. 120(20). 4172–4181. 102 indexed citations
13.
Sandler, Netanya G., Handan Wand, Annelys Roque, et al.. (2011). Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection. The Journal of Infectious Diseases. 203(6). 780–790. 856 indexed citations breakdown →
14.
Favre, David, Jeff E. Mold, Peter W. Hunt, et al.. (2010). Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of T H 17 to Regulatory T Cells in HIV Disease. Science Translational Medicine. 2(32). 32ra36–32ra36. 423 indexed citations
15.
Engram, Jessica C., Barbara Cervasi, José A. M. Borghans, et al.. (2010). Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates. Blood. 116(5). 748–758. 25 indexed citations
16.
Brenchley, Jason M., Guido Silvestri, & Daniel C. Douek. (2010). Nonprogressive and Progressive Primate Immunodeficiency Lentivirus Infections. Immunity. 32(6). 737–742. 81 indexed citations
17.
Jiang, Wei, Michael M. Lederman, Peter W. Hunt, et al.. (2009). Plasma Levels of Bacterial DNA Correlate with Immune Activation and the Magnitude of Immune Restoration in Persons with Antiretroviral‐Treated HIV Infection. The Journal of Infectious Diseases. 199(8). 1177–1185. 463 indexed citations breakdown →
18.
Brenchley, Jason M., Timothy W. Schacker, Laura E. Ruff, et al.. (2004). CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract. The Journal of Experimental Medicine. 200(6). 749–759. 1353 indexed citations breakdown →
19.
Betts, Michael R., David R. Ambrozak, Daniel C. Douek, et al.. (2001). Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4 + and CD8 + T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection. Journal of Virology. 75(24). 11983–11991. 574 indexed citations breakdown →
20.
Lang, Patrick, et al.. (1998). Cyclic Subspace Regression. Journal of Multivariate Analysis. 65(1). 58–70. 20 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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