Zhiya Yu

22.4k total citations · 8 hit papers
95 papers, 14.2k citations indexed

About

Zhiya Yu is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Zhiya Yu has authored 95 papers receiving a total of 14.2k indexed citations (citations by other indexed papers that have themselves been cited), including 71 papers in Immunology, 69 papers in Oncology and 22 papers in Molecular Biology. Recurrent topics in Zhiya Yu's work include CAR-T cell therapy research (62 papers), Immunotherapy and Immune Responses (50 papers) and Immune Cell Function and Interaction (34 papers). Zhiya Yu is often cited by papers focused on CAR-T cell therapy research (62 papers), Immunotherapy and Immune Responses (50 papers) and Immune Cell Function and Interaction (34 papers). Zhiya Yu collaborates with scholars based in United States, United Kingdom and Malaysia. Zhiya Yu's co-authors include Nicholas P. Restifo, Steven A. Rosenberg, Douglas C. Palmer, Luca Gattinoni, Christopher A. Klebanoff, Pawel Muranski, Vanda A. Lennon, Yun Ji, Dhanalakshmi Chinnasamy and Chrystal M. Paulos and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Zhiya Yu

91 papers receiving 14.0k citations

Hit Papers

A human memory T cell subset with stem cell–like properties 2003 2026 2010 2018 2011 2005 2009 2003 2013 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A human memory T cell subset with stem cell–like properties
    2011 1.4k citations Luca Gattinoni, Zhiya Yu et al. profile →
  2. Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8 + T cells
    2005 812 citations Luca Gattinoni, Steven E. Finkelstein et al. The Journal of Experimental Medicine profile →
  3. Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
    2009 762 citations Luca Gattinoni, Douglas C. Palmer et al. profile →
  4. Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells
    2003 751 citations Marc R. Theoret, Steven E. Finkelstein et al. The Journal of Experimental Medicine profile →
  5. Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
    2013 718 citations Zhiya Yu, Douglas C. Palmer et al. Journal of Clinical Investigation profile →
  6. Antiangiogenic Agents Can Increase Lymphocyte Infiltration into Tumor and Enhance the Effectiveness of Adoptive Immunotherapy of Cancer
    2010 518 citations Rajeev Shrimali, Zhiya Yu et al. Cancer Research profile →
  7. Ionic immune suppression within the tumour microenvironment limits T cell effector function
    2016 489 citations Christopher A. Klebanoff, Douglas C. Palmer et al. profile →
  8. T cell stemness and dysfunction in tumors are triggered by a common mechanism
    2019 409 citations Rigel J. Kishton, Zhiya Yu et al. profile →

Peers

Zhiya Yu
Dario Campana United States
Udai S. Kammula United States
James L. Riley United States
Phillip K. Darcy Australia
Luca Gattinoni United States
Claudio Bordignon Italy
Cassian Yee United States
Michael H. Kershaw Australia
Catia Traversari Italy
Koji Tamada Japan
Dario Campana United States
Zhiya Yu
Citations per year, relative to Zhiya Yu Zhiya Yu (= 1×) peers Dario Campana

Countries citing papers authored by Zhiya Yu

Since Specialization
Citations

This map shows the geographic impact of Zhiya Yu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhiya Yu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhiya Yu more than expected).

Fields of papers citing papers by Zhiya Yu

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhiya Yu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhiya Yu. The network helps show where Zhiya Yu may publish in the future.

Co-authorship network of co-authors of Zhiya Yu

This figure shows the co-authorship network connecting the top 25 collaborators of Zhiya Yu. A scholar is included among the top collaborators of Zhiya Yu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhiya Yu. Zhiya Yu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Sim, Malcolm J. W., Ken‐ichi Hanada, Zhiya Yu, et al.. (2024). Identification and structural characterization of a mutant KRAS‐G12V specific TCR restricted by HLA‐A3. European Journal of Immunology. 54(9). e2451079–e2451079. 1 indexed citations
2.
Li, Angela, Liaofu Luo, Wei Du, et al.. (2023). P2.05-10 The Power for PD-L1 Expression to Predict Immune Checkpoint Blockade Outcomes is Determined by Tumor Transcriptome. Journal of Thoracic Oncology. 18(11). S311–S312.
3.
Islam, S.M. Rafiqul, Naritaka Tamaoki, Rigel J. Kishton, et al.. (2023). Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells. Cancer Research Communications. 3(5). 917–932. 6 indexed citations
4.
Levin, Noam, Biman C. Paria, Nolan R. Vale, et al.. (2021). Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy. Clinical Cancer Research. 27(18). 5084–5095. 29 indexed citations
5.
Wang, Qiong J., Zhiya Yu, Ken‐ichi Hanada, et al.. (2016). Preclinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers. Clinical Cancer Research. 23(9). 2267–2276. 65 indexed citations
6.
Wang, Qiong J., et al.. (2016). Identification of T-cell Receptors Targeting KRAS-Mutated Human Tumors. Cancer Immunology Research. 4(3). 204–214. 175 indexed citations
7.
Slaney, Clare Y., Bianca von Scheidt, Alexander J. Davenport, et al.. (2016). Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting. Clinical Cancer Research. 23(10). 2478–2490. 89 indexed citations
8.
Shi, Zhong, Zhiya Yu, Ivan Liadi, et al.. (2016). Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets. The Journal of Immunology. 197(2). 644–654. 16 indexed citations
9.
Shi, Zhong, Karolina Malecek, Laura A. Johnson, et al.. (2013). T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy. Proceedings of the National Academy of Sciences. 110(17). 6973–6978. 178 indexed citations
10.
Chinnasamy, Dhanalakshmi, Eric Tran, Zhiya Yu, et al.. (2013). Simultaneous Targeting of Tumor Antigens and the Tumor Vasculature Using T Lymphocyte Transfer Synergize to Induce Regression of Established Tumors in Mice. Cancer Research. 73(11). 3371–3380. 90 indexed citations
11.
Tran, Eric, Dhanalakshmi Chinnasamy, Zhiya Yu, et al.. (2013). Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia. The Journal of Experimental Medicine. 210(6). 1125–1135. 349 indexed citations
12.
Krogsgaard, Michelle, Zhong Shi, Karolina Malecek, et al.. (2013). T cell receptor affinity and avidity defines antitumor response and autoimmunity in T cell immunotherapy. Journal for ImmunoTherapy of Cancer. 1(S1). 13 indexed citations
13.
Chinnasamy, Dhanalakshmi, Zhiya Yu, Sid P. Kerkar, et al.. (2012). Local Delivery of lnterleukin-12 Using T Cells Targeting VEGF Receptor-2 Eradicates Multiple Vascularized Tumors in Mice. Clinical Cancer Research. 18(6). 1672–1683. 234 indexed citations
14.
Kerkar, Sid P., Pawel Muranski, Andrew Kaiser, et al.. (2010). Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts. Cancer Research. 70(17). 6725–6734. 207 indexed citations
15.
Chinnasamy, Dhanalakshmi, Zhiya Yu, Marc R. Theoret, et al.. (2010). Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice. Journal of Clinical Investigation. 120(11). 3953–3968. 205 indexed citations
16.
Frankel, Timothy L., William R. Burns, Peter D. Peng, et al.. (2010). Both CD4 and CD8 T Cells Mediate Equally Effective In Vivo Tumor Treatment When Engineered with a Highly Avid TCR Targeting Tyrosinase. The Journal of Immunology. 184(11). 5988–5998. 60 indexed citations
17.
Parkhurst, Maria R., John P. Riley, Zhiya Yu, et al.. (2008). Characterization of Genetically Modified T-Cell Receptors that Recognize the CEA:691-699 Peptide in the Context of HLA-A2.1 on Human Colorectal Cancer Cells. Clinical Cancer Research. 15(1). 169–180. 89 indexed citations
18.
Gattinoni, Luca, Steven E. Finkelstein, Christopher A. Klebanoff, et al.. (2005). Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8 + T cells. The Journal of Experimental Medicine. 202(7). 907–912. 812 indexed citations breakdown →
19.
Borbulevych, Oleg Y., Tiffany K. Baxter, Zhiya Yu, Nicholas P. Restifo, & Brian M. Baker. (2005). Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design. The Journal of Immunology. 174(8). 4812–4820. 89 indexed citations
20.
Palmer, Douglas C., Sanjeeve Balasubramaniam, Ken‐ichi Hanada, et al.. (2004). Vaccine-Stimulated, Adoptively Transferred CD8+ T Cells Traffic Indiscriminately and Ubiquitously while Mediating Specific Tumor Destruction. The Journal of Immunology. 173(12). 7209–7216. 97 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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