Antonio Lanzavecchia

111.2k citations
349 papers · 77.0k indexed · 43 hit papers · h-index 129
Co-authors
Federica SallustoMarina CellaDanielle LenigJens GeginatMartin LippCharles R. MackayReinhold FörsterGiorgio Napolitani
Topics
T-cell and B-cell Immunology (188 papers)Immune Cell Function and Interaction (145 papers)Immunotherapy and Immune Responses (135 papers)
Cited by
ImmunologyVirologyImmunology and Allergy
Journals
NatureScienceCell
Partner nations
SwitzerlandItalyUnited States

In The Last Decade

Antonio Lanzavecchia

343 papers receiving 75.1k citations

Hit Papers

Two subsets of memory T lymphocytes with distinct homing ...19852026199820121999199420041996200710002.0k3.0k4.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    1999 4.6k citations Federica Sallusto, Martin Lipp et al. Nature profile →
  2. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.
    1994 4.4k citations Federica Sallusto, Antonio Lanzavecchia The Journal of Experimental Medicine profile →
  3. Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance
    2004 2.3k citations Federica Sallusto, Jens Geginat et al. profile →
  4. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.
    1996 1.7k citations Antonio Lanzavecchia et al. The Journal of Experimental Medicine profile →
  5. Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells
    2007 1.5k citations Antonio Lanzavecchia, Federica Sallusto et al. profile →
  6. Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells
    2007 1.4k citations Laura Rivino, Jens Geginat et al. profile →
  7. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon
    1999 1.4k citations David Jarrossay, Antonio Lanzavecchia et al. profile →
  8. Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes
    1998 1.3k citations Federica Sallusto, Antonio Lanzavecchia et al. The Journal of Experimental Medicine profile →
  9. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
    2016 1.2k citations Roger Geiger, Federica Sallusto et al. profile →
  10. Antigen-specific interaction between T and B cells
    1985 1.2k citations Antonio Lanzavecchia Nature profile →
  11. Origin, maturation and antigen presenting function of dendritic cells
    1997 1.1k citations Federica Sallusto, Antonio Lanzavecchia et al. profile →
  12. Induced recruitment of NK cells to lymph nodes provides IFN-γ for TH1 priming
    2004 1.1k citations Martin Lipp, Antonio Lanzavecchia et al. profile →
  13. Maintenance of Serological Memory by Polyclonal Activation of Human Memory B Cells
    2002 1.0k citations Elisabetta Traggiai, Antonio Lanzavecchia et al. Science profile →
  14. Serial triggering of many T-cell receptors by a few peptide–MHC complexes
    1995 964 citations Elisabetta Padovan, Antonio Lanzavecchia et al. Nature profile →
  15. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells
    2005 957 citations Federica Sallusto, Antonio Lanzavecchia et al. profile →
  16. Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells
    2000 945 citations Antonio Lanzavecchia, Federica Sallusto et al. profile →
  17. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
    1997 933 citations Antonio Lanzavecchia et al. Nature profile →
  18. C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
    2009 929 citations Antonio Lanzavecchia, Federica Sallusto et al. profile →
  19. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
    1998 907 citations Federica Sallusto, Antonio Lanzavecchia et al. profile →
  20. Selective Expression of the Eotaxin Receptor CCR3 by Human T Helper 2 Cells
    1997 905 citations Federica Sallusto, Antonio Lanzavecchia et al. Science profile →
  21. The Role of Chemokine Receptors in Primary, Effector, and Memory Immune Responses
    2000 876 citations Federica Sallusto, Antonio Lanzavecchia et al. profile →
  22. T Cell Activation Determined by T Cell Receptor Number and Tunable Thresholds
    1996 869 citations Antonio Lanzavecchia et al. Science profile →
  23. T Lymphocyte Costimulation Mediated by Reorganization of Membrane Microdomains
    1999 836 citations Antonio Lanzavecchia et al. Science profile →
  24. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    2009 823 citations David Jarrossay, Antonio Lanzavecchia et al. profile →
  25. Regulation of T Cell Immunity by Dendritic Cells
    2001 805 citations Antonio Lanzavecchia, Federica Sallusto profile →
  26. Development of a Human Adaptive Immune System in Cord Blood Cell-Transplanted Mice
    2004 786 citations Elisabetta Traggiai, Laurie Chicha et al. Science profile →
  27. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
    1998 772 citations Federica Sallusto, Antonio Lanzavecchia et al. profile →
  28. The Duration of Antigenic Stimulation Determines the Fate of Naive and Effector T Cells
    1998 754 citations Antonio Lanzavecchia et al. profile →
  29. Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
    2012 722 citations Federico Mele, David Jarrossay et al. Nature profile →
  30. Regulation of Dendritic Cell Migration to the Draining Lymph Node
    2003 716 citations Martin Lipp, Antonio Lanzavecchia et al. The Journal of Experimental Medicine profile →
  31. Dynamics of T Lymphocyte Responses: Intermediates, Effectors, and Memory Cells
    2000 639 citations Antonio Lanzavecchia, Federica Sallusto Science profile →
  32. Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization
    2000 638 citations Antonio Lanzavecchia et al. profile →
  33. Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells
    1989 619 citations Antonio Lanzavecchia et al. profile →
  34. Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
    2001 619 citations David Jarrossay, Federica Sallusto et al. profile →
  35. Maturation, Activation, and Protection of Dendritic Cells Induced by Double-stranded RNA
    1999 609 citations Mariolina Salio, Antonio Lanzavecchia et al. The Journal of Experimental Medicine profile →
  36. BDCA-2, a Novel Plasmacytoid Dendritic Cell–specific Type II C-type Lectin, Mediates Antigen Capture and Is a Potent Inhibitor of Interferon α/β Induction
    2001 593 citations Antonio Lanzavecchia et al. The Journal of Experimental Medicine profile →
  37. A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
    2015 560 citations Antonio Lanzavecchia et al. profile →
  38. Distinct patterns and kinetics of chemokine production regulate dendritic cell function
    1999 559 citations Federica Sallusto, Martin Lipp et al. profile →
  39. A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
    2003 545 citations Antonio Lanzavecchia et al. Blood profile →
  40. An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus
    2004 541 citations Elisabetta Traggiai, Antonio Lanzavecchia et al. profile →
  41. The Dendritic Cell-Specific Adhesion Receptor DC-SIGN Internalizes Antigen for Presentation to T Cells
    2002 514 citations Antonio Lanzavecchia et al. The Journal of Immunology profile →
  42. Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
    2016 512 citations Christoph T. Ellebrecht, Vijay Bhoj et al. Science profile →
  43. Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion
    2019 370 citations Antonio Lanzavecchia, Davide Corti et al. profile →

Peers

Antonio Lanzavecchia
Comparison fields: 5 of 176
  • Immunology 57.5k
  • Molecular Biology 13.1k
  • Oncology 12.9k
  • Epidemiology 9.6k
  • Infectious Diseases 8.2k
Replace Ralph M. Steinman with:
Ralph M. Steinman United States
Jacques Banchereau United States
Giorgio Trinchieri United States
Federica Sallusto Switzerland
Robert L. Coffman United States
Charles R. Mackay Australia
Andrew D. Luster United States
Nico van Rooijen Netherlands
Alessandro Sette United States
Lewis L. Lanier United States
Antonio Lanzavecchia relative to Ralph M. Steinman United States Ralph M. Steinman's profile →
Citations per field
00.5×1.5×2×2.3×
Ralph M. Steinman · 1×
Citations per year

Countries citing papers authored by Antonio Lanzavecchia

Since Specialization
Citations

This map shows the geographic impact of Antonio Lanzavecchia's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Antonio Lanzavecchia with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Antonio Lanzavecchia more than expected).

Fields of papers citing papers by Antonio Lanzavecchia

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Antonio Lanzavecchia. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Antonio Lanzavecchia. The network helps show where Antonio Lanzavecchia may publish in the future.

Co-authorship network of co-authors of Antonio Lanzavecchia

This figure shows the co-authorship network connecting the top 25 collaborators of Antonio Lanzavecchia. A scholar is included among the top collaborators of Antonio Lanzavecchia based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Antonio Lanzavecchia. Antonio Lanzavecchia is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
#WorkIndexed citations
1
Different classes of genomic inserts contribute to human antibody diversity
2022 ·Proceedings of the National Academy of Sciences ·(unknown),Mathilde Foglierini,(unknown),(unknown),(unknown),Alexey N. Davydov,Maria A. Turchaninova,Claudia Daubenberger,Dmitriy M. Chudakov,Antonio Lanzavecchia,(unknown)
8
2
Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs
2021 ·Nature Communications ·Kai Xu,Yiran Wang,Chen‐Hsiang Shen,Yiwei Chen,Baoshan Zhang,Kevin Liu,Yaroslav Tsybovsky,Shuishu Wang,S. Katie Farney,Jason Gorman,Tyler Stephens,Raffaello Verardi,Yongping Yang,Tongqing Zhou,Gwo‐Yu Chuang,Antonio Lanzavecchia,Luca Piccoli,Peter D. Kwong
6
3
Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2
2021 ·Science ·Jun Siong Low,(unknown),Federico Mele,Mathilde Foglierini,Josipa Jerak,Michela Perotti,David Jarrossay,Sandra Jovic,Laurent Perez,(unknown),Tatiana Terrot,Alessandra Franzetti-Pellanda,Maira Biggiogero,Christian Garzoni,Paolo Ferrari,Alessandro Ceschi,Antonio Lanzavecchia,Federica Sallusto,Antonino Cassotta
85
4
Structural basis of malaria RIFIN binding by LILRB1-containing antibodies
2021 ·Nature ·Yiwei Chen,Kai Xu,Luca Piccoli,Mathilde Foglierini,Joshua Tan,Wenjie Jin,Jason Gorman,Yaroslav Tsybovsky,Baoshan Zhang,Boubacar Traoré,Chiara Silacci-Fregni,Claudia Daubenberger,Peter D. Crompton,Roger Geiger,Federica Sallusto,Peter D. Kwong,Antonio Lanzavecchia
14
5
Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles
2019 ·Science Immunology ·Velislava Petrova,Bevan Sawatsky,Alvin X. Han,Brigitta M. Laksono,Lisa Walz,Edyth Parker,Kathrin Pieper,Carl A. Anderson,Rory D. de Vries,Antonio Lanzavecchia,Paul Kellam,Veronika von Messling,Rik L. de Swart,Colin A. Russell
82
6
Pillars Article: Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α.J. Exp. Med. 1994. 179:1109–1118
2018 ·The Journal of Immunology ·Federica Sallusto,Antonio Lanzavecchia
1
7
Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus
2017 ·PLoS ONE ·Mallika Sastry,Baoshan Zhang,Man Chen,Michael Joyce,Wing‐Pui Kong,Gwo‐Yu Chuang,(unknown),Azad Kumar,Chiara Silacci,Michelle Thom,Andres Μ. Salazar,Davide Corti,Antonio Lanzavecchia,Geraldine Taylor,John R. Mascola,Barney S. Graham,Peter D. Kwong
39
8
Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune diseasebreakdown →
2016 ·Science ·Christoph T. Ellebrecht,Vijay Bhoj,Arben Nace,Eun Jung Choi,Xuming Mao,Michael Jeffrey Cho,Giovanni Di Zenzo,Antonio Lanzavecchia,John T. Seykora,George Cotsarelis,Michael C. Milone,Aimee Payne
512
9
Structural and molecular basis for Ebola virus neutralization by protective human antibodies
2016 ·Science ·John Misasi,Morgan S. A. Gilman,Masaru Kanekiyo,Miao Gui,Alberto Cagigi,Sabue Mulangu,Davide Corti,Julie E. Ledgerwood,Antonio Lanzavecchia,James M. Cunningham,(unknown),Ulrich Baxa,Barney S. Graham,Ye Xiang,Nancy J. Sullivan,Jason S. McLellan
135
10
Development of broad‐spectrum human monoclonal antibodies for rabies post‐exposure prophylaxis
2016 ·EMBO Molecular Medicine ·Paola De Benedictis,Andrea Minola,(unknown),(unknown),(unknown),Angela Salomoni,Mathilde Foglierini,Gloria Agatic,Fabrizia Vanzetta,Rachel Lavenir,Anthony Lepelletier,Emma Bentley,Robin A. Weiss,Giovanni Cattoli,Ilaria Capua,Federica Sallusto,Edward Wright,Antonio Lanzavecchia,Hervé Bourhy,Davide Corti
73
11
Functional heterogeneity of human memory CD4 + T cell clones primed by pathogens or vaccines
2014 ·Science ·Simone Becattini,Daniela Latorre,Federico Mele,Mathilde Foglierini,Corinne De Gregorio,Antonino Cassotta,(unknown),Sander Kelderman,Ton N. Schumacher,Davide Corti,Antonio Lanzavecchia,Federica Sallusto
239
12
CCR6 is expressed on an IL-10–producing, autoreactive memory T cell population with context-dependent regulatory function
2010 ·The Journal of Experimental Medicine ·Laura Rivino,Paola Gruarin,(unknown),Svenja Steinfelder,Laura Lozza,Bodo Steckel,(unknown),(unknown),David Jarrossay,Anja A. Kühl,Christoph Loddenkemper,Sergio Abrignani,Federica Sallusto,Antonio Lanzavecchia,Jens Geginat
51
13
Development of a Human Adaptive Immune System in Cord Blood Cell-Transplanted Micebreakdown →
2004 ·Science ·Elisabetta Traggiai,Laurie Chicha,Luca Mazzucchelli,L. Bronz,Jean-Claude Piffaretti,Antonio Lanzavecchia,Markus G. Manz
786
14
Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines
2003 ·Blood ·Jens Geginat,Antonio Lanzavecchia,Federica Sallusto
464
15
Antigen dependent and independent mechanisms that sustain serum antibody levels
2003 ·Vaccine ·Elisabetta Traggiai,Roberto Puzone,Antonio Lanzavecchia
107
16
A Shift in the Phenotype of Melan-A-Specific CTL Identifies Melanoma Patients with an Active Tumor-Specific Immune Response
2000 ·The Journal of Immunology ·P. Rod Dunbar,C. Smith,David Chao,Mariolina Salio,Dawn Shepherd,Fareed Mirza,Martin Lipp,Antonio Lanzavecchia,Federica Sallusto,A. V. Evans,R. Russell‐Jones,Adrian L. Harris,Vincenzo Cerundolo
122
17
κ+λ+ dual receptor B cells are present in the human peripheral repertoire.
1995 ·The Journal of Experimental Medicine ·Claudia Giachino,Elisabetta Padovan,Antonio Lanzavecchia
86
18
Characterization of granzymes A and B isolated from granules of cloned human cytotoxic T lymphocytes.
1988 ·The Journal of Immunology ·Olivier Krähenbühl,(unknown),Dieter E. Jenne,Antonio Lanzavecchia,Peter Groscurth,S Carrel,J Tschopp
104
19
Kinetics of MHC-antigen complex formation on antigen-presenting cells.
1988 ·The Journal of Immunology ·Eddy Roosnek,Stéphane Demotz,G Corradin,Antonio Lanzavecchia
58
20
In vitro Synthesis of Human IgE: Reappraisal of a 5-Year Study
1985 ·International Archives of Allergy and Immunology ·M Ricci,G. Prete,Enrico Maggi,Antonio Lanzavecchia,(unknown),Sergio Romagnani
32

About Antonio Lanzavecchia

Antonio Lanzavecchia is a scholar working on Immunology, Virology and Radiology, Nuclear Medicine and Imaging, having authored 349 papers that have together received 77.0k indexed citations. Recurring topics across this work include T-cell and B-cell Immunology (188 papers), Immune Cell Function and Interaction (145 papers) and Immunotherapy and Immune Responses (135 papers). The work is most often cited by research in Immunology (57.5k citations), Virology (3.9k citations) and Immunology and Allergy (2.9k citations). Antonio Lanzavecchia has collaborated with scholars based in Switzerland, Italy and United States. Frequent co-authors include Federica Sallusto, Marina Cella, Danielle Lenig, Jens Geginat, Martin Lipp, Charles R. Mackay, Reinhold Förster, Giorgio Napolitani, David Jarrossay and Antonella Viola. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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