Alan Sher

72.2k total citations · 23 hit papers
449 papers, 57.2k citations indexed

About

Alan Sher is a scholar working on Parasitology, Immunology and Epidemiology. According to data from OpenAlex, Alan Sher has authored 449 papers receiving a total of 57.2k indexed citations (citations by other indexed papers that have themselves been cited), including 233 papers in Parasitology, 202 papers in Immunology and 158 papers in Epidemiology. Recurrent topics in Alan Sher's work include Parasites and Host Interactions (129 papers), Toxoplasma gondii Research Studies (102 papers) and Immune Cell Function and Interaction (88 papers). Alan Sher is often cited by papers focused on Parasites and Host Interactions (129 papers), Toxoplasma gondii Research Studies (102 papers) and Immune Cell Function and Interaction (88 papers). Alan Sher collaborates with scholars based in United States, United Kingdom and Brazil. Alan Sher's co-authors include Sara Hieny, Ricardo T. Gazzinelli, Kenneth M. Murphy, Abul K. Abbas, Allen W. Cheever, Dragana Janković, Júlio Aliberti, Patricia Caspar, Carl G. Feng and Robert L. Coffman and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Alan Sher

447 papers receiving 55.8k citations

Hit Papers

Functional diversity of h... 1988 2026 2000 2013 1996 2000 2015 2010 2012 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Functional diversity of helper T lymphocytes
    1996 3.7k citations Alan Sher et al. profile →
  2. Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion
    2000 2.0k citations Júlio Aliberti, Alan Sher et al. profile →
  3. Type I interferons in infectious disease
    2015 1.9k citations Katrin D. Mayer-Barber, Alan Sher et al. profile →
  4. Vaccine Adjuvants: Putting Innate Immunity to Work
    2010 1.4k citations Alan Sher, Robert A. Seder et al. Immunity profile →
  5. Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
    2012 1.1k citations Kevin Shenderov, Alan Sher et al. profile →
  6. Cooperation of Toll-like receptor signals in innate immune defence
    2007 1.1k citations Giorgio Trinchieri, Alan Sher profile →
  7. A Critical Role for IL-21 in Regulating Immunoglobulin Production
    2002 786 citations Katsutoshi Ozaki, Rosanne Spolski et al. Science profile →
  8. TLR11 Activation of Dendritic Cells by a Protozoan Profilin-Like Protein
    2005 772 citations Felix Yarovinsky, Dekai Zhang et al. Science profile →
  9. In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α
    1996 760 citations Ricardo T. Gazzinelli, Maria Wysocka et al. The Journal of Immunology profile →
  10. In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas
    1997 752 citations Caetano Reis e Sousa, Sara Hieny et al. The Journal of Experimental Medicine profile →
  11. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1
    2005 741 citations Júlio Aliberti, Alan Sher et al. The Journal of Experimental Medicine profile →
  12. Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts.
    1993 702 citations Ricardo T. Gazzinelli, Sara Hieny et al. profile →
  13. Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni.
    1991 664 citations Patricia Caspar, Alan Sher et al. The Journal of Experimental Medicine profile →
  14. T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells
    2001 618 citations Dragana Janković, Júlio Aliberti et al. profile →
  15. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens.
    1988 609 citations Phillip Scott, Alan Sher et al. The Journal of Experimental Medicine profile →
  16. IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages
    1992 592 citations Ricardo T. Gazzinelli, Alan Sher et al. The Journal of Immunology profile →
  17. Parasite-induced IL-12 stimulates early IFN- gamma synthesis and resistance during acute infection with Toxoplasma gondii .
    1994 588 citations Ricardo T. Gazzinelli, Maria Wysocka et al. The Journal of Immunology profile →
  18. Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
    2014 567 citations Katrin D. Mayer-Barber, Sandra D. Oland et al. profile →
  19. Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine
    1991 517 citations Ricardo T. Gazzinelli, Sara Hieny et al. The Journal of Immunology profile →
  20. Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii
    1992 475 citations Ricardo T. Gazzinelli, Sara Hieny et al. The Journal of Immunology profile →
  21. Role of T‐Cell Derived Cytokines in the Downregulation of Immune Responses in Parasitic and Retroviral Infection
    1992 402 citations Alan Sher, Ricardo T. Gazzinelli et al. profile →
  22. A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis
    2019 310 citations Diego L. Costa, Sivaranjani Namasivayam et al. The Journal of Experimental Medicine profile →
  23. Host-directed immunotherapy of viral and bacterial infections: past, present and future
    2022 151 citations Alan Sher et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Alan Sher 29.2k 16.5k 16.0k 9.8k 8.5k 449 57.2k
Thomas A. Wynn 21.0k 0.7× 7.3k 0.4× 7.9k 0.5× 11.5k 1.2× 3.0k 0.4× 232 53.1k
Edward J. Pearce 17.7k 0.6× 4.2k 0.3× 9.4k 0.6× 9.5k 1.0× 2.8k 0.3× 227 36.1k
Robert L. Coffman 39.5k 1.4× 9.0k 0.5× 3.2k 0.2× 8.8k 0.9× 4.4k 0.5× 256 60.9k
Richard M. Locksley 32.5k 1.1× 8.9k 0.5× 3.0k 0.2× 7.9k 0.8× 3.3k 0.4× 271 51.4k
Yasmine Belkaid 20.4k 0.7× 6.0k 0.4× 2.3k 0.1× 10.5k 1.1× 4.7k 0.6× 217 39.8k
Ruslan Medzhitov 61.3k 2.1× 13.4k 0.8× 2.2k 0.1× 27.9k 2.8× 7.3k 0.9× 227 97.2k
Herbert W. Virgin 10.5k 0.4× 16.0k 1.0× 1.8k 0.1× 12.7k 1.3× 10.4k 1.2× 258 38.7k
Nico van Rooijen 38.1k 1.3× 13.1k 0.8× 2.2k 0.1× 21.4k 2.2× 4.9k 0.6× 838 80.5k
Douglas T. Golenbock 30.7k 1.1× 10.7k 0.6× 2.0k 0.1× 15.2k 1.5× 4.8k 0.6× 288 51.0k
Giorgio Trinchieri 46.8k 1.6× 10.2k 0.6× 2.6k 0.2× 13.0k 1.3× 4.8k 0.6× 434 67.5k

Countries citing papers authored by Alan Sher

Since Specialization
Citations

This map shows the geographic impact of Alan Sher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan Sher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan Sher more than expected).

Fields of papers citing papers by Alan Sher

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan Sher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan Sher. The network helps show where Alan Sher may publish in the future.

Co-authorship network of co-authors of Alan Sher

This figure shows the co-authorship network connecting the top 25 collaborators of Alan Sher. A scholar is included among the top collaborators of Alan Sher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alan Sher. Alan Sher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Karanika, Styliani, Stefanie Krug, Andrew Garcia, et al.. (2023). The heme oxygenase-1 metalloporphyrin inhibitor stannsoporfin enhances the bactericidal activity of a novel regimen for multidrug-resistant tuberculosis in a murine model. Antimicrobial Agents and Chemotherapy. 68(2). e0104323–e0104323. 4 indexed citations
2.
Hilligan, Kerry L., Sivaranjani Namasivayam, Chad S. Clancy, et al.. (2021). Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge. The Journal of Experimental Medicine. 219(2). 69 indexed citations
3.
Namasivayam, Sivaranjani, Alan Sher, Michael S. Glickman, & Matthew F. Wipperman. (2018). The Microbiome and Tuberculosis: Early Evidence for Cross Talk. mBio. 9(5). 65 indexed citations
4.
Kugler, David, Francis A. Flomerfelt, Diego L. Costa, et al.. (2016). Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes. The Journal of Experimental Medicine. 213(13). 3041–3056. 25 indexed citations
5.
Tosh, Kevin, Lara Mittereder, Sandra Bonne-Année, et al.. (2015). The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion. The Journal of Immunology. 196(1). 345–356. 62 indexed citations
6.
Wasmuth, James D., Viviana Pszenny, Simon Haile, et al.. (2012). Integrated Bioinformatic and Targeted Deletion Analyses of the SRS Gene Superfamily Identify SRS29C as a Negative Regulator of Toxoplasma Virulence. mBio. 3(6). 65 indexed citations
7.
Cardone, Marco, Robert W. Thompson, Kevin Shenderov, et al.. (2011). Mycobacterium tuberculosis Triggers Host Type I IFN Signaling To Regulate IL-1β Production in Human Macrophages. The Journal of Immunology. 187(5). 2540–2547. 193 indexed citations
8.
Barber, Daniel L., Katrin D. Mayer-Barber, Carl G. Feng, Arlene H. Sharpe, & Alan Sher. (2010). CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1–Mediated Inhibition. The Journal of Immunology. 186(3). 1598–1607. 255 indexed citations
9.
Steinfelder, Svenja, John F. Andersen, Jennifer L. Cannons, et al.. (2009). The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). The Journal of Experimental Medicine. 206(8). 1681–1690. 241 indexed citations
10.
Goldszmid, Romina S., Isabelle Coppens, Avital Lev, et al.. (2009). Host ER–parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii –infected dendritic cells. The Journal of Experimental Medicine. 206(2). 399–410. 124 indexed citations
11.
Janković, Dragana, Marika C. Kullberg, Carl G. Feng, et al.. (2007). Conventional T-bet+Foxp3− Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. The Journal of Experimental Medicine. 204(2). 273–283. 469 indexed citations
12.
Yarovinsky, Felix, Dekai Zhang, John F. Andersen, et al.. (2005). TLR11 Activation of Dendritic Cells by a Protozoan Profilin-Like Protein. Science. 308(5728). 1626–1629. 772 indexed citations breakdown →
13.
Chaussabel, Damien, Roshanak Tolouei Semnani, Mary Ann McDowell, et al.. (2003). Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites. Blood. 102(2). 672–681. 257 indexed citations
14.
Schito, Marco, Atul Goel, Yongsheng Song, et al.. (2003). In Vivo Antiviral Activity of Novel Human Immunodeficiency Virus Type 1 Nucleocapsid p7 Zinc Finger Inhibitors in a Transgenic Murine Model. AIDS Research and Human Retroviruses. 19(2). 91–101. 35 indexed citations
15.
Edwards, Alexander D., Damien Chaussabel, Simon R. Tomlinson, et al.. (2003). Relationships Among Murine CD11chigh Dendritic Cell Subsets as Revealed by Baseline Gene Expression Patterns. The Journal of Immunology. 171(1). 47–60. 102 indexed citations
16.
Ozaki, Katsutoshi, Rosanne Spolski, Carl G. Feng, et al.. (2002). A Critical Role for IL-21 in Regulating Immunoglobulin Production. Science. 298(5598). 1630–1634. 786 indexed citations breakdown →
17.
Sousa, Caetano Reis e, George Yap, Oliver Schulz, et al.. (1999). Paralysis of Dendritic Cell IL-12 Production by Microbial Products Prevents Infection-Induced Immunopathology. Immunity. 11(5). 637–647. 162 indexed citations
18.
Doherty, T. Mark, Robert A. Seder, & Alan Sher. (1996). Induction and regulation of IL-15 expression in murine macrophages. The Journal of Immunology. 156(2). 735–741. 289 indexed citations
19.
Gazzinelli, Ricardo T., Maria Wysocka, Seiji Hayashi, et al.. (1994). Parasite-induced IL-12 stimulates early IFN- gamma synthesis and resistance during acute infection with Toxoplasma gondii .. The Journal of Immunology. 153(6). 2533–2543. 588 indexed citations breakdown →
20.
Sher, Alan & Phillip Scott. (1982). Genetic Factors Influencing the Interaction of Parasites with the Immune System. 2(3). 489–510. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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