Adrian R. Krainer

36.9k total citations · 13 hit papers
179 papers, 28.0k citations indexed

About

Adrian R. Krainer is a scholar working on Molecular Biology, Genetics and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Adrian R. Krainer has authored 179 papers receiving a total of 28.0k indexed citations (citations by other indexed papers that have themselves been cited), including 174 papers in Molecular Biology, 34 papers in Genetics and 14 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Adrian R. Krainer's work include RNA Research and Splicing (152 papers), RNA and protein synthesis mechanisms (97 papers) and RNA modifications and cancer (93 papers). Adrian R. Krainer is often cited by papers focused on RNA Research and Splicing (152 papers), RNA and protein synthesis mechanisms (97 papers) and RNA modifications and cancer (93 papers). Adrian R. Krainer collaborates with scholars based in United States, United Kingdom and China. Adrian R. Krainer's co-authors include Luca Cartegni, Akila Mayeda, Shern L. Chew, Tom Maniatis, C. Frank Bennett, Yimin Hua, Javier F. Cáceres, Michelle L. Hastings, Michael Q. Zhang and Frank Rigo and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Adrian R. Krainer

177 papers receiving 27.6k citations

Hit Papers

Listening to silence and ... 1984 2026 1998 2012 2002 2012 2014 2007 1984 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Listening to silence and understanding nonsense: exonic mutations that affect splicing
    2002 1.7k citations Luca Cartegni, Shern L. Chew et al. profile →
  2. RNA therapeutics: beyond RNA interference and antisense oligonucleotides
    2012 916 citations Ryszard Kole, Adrian R. Krainer et al. Nature Reviews Drug Discovery profile →
  3. The human splicing code reveals new insights into the genetic determinants of disease
    2014 829 citations Hui Xiong, Babak Alipanahi et al. Science profile →
  4. The gene encoding the splicing factor SF2/ASF is a proto-oncogene
    2007 720 citations Rotem Karni, Adrian R. Krainer et al. Nature Structural & Molecular Biology profile →
  5. Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro
    1984 671 citations Adrian R. Krainer et al. profile →
  6. CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function
    2015 648 citations Adrian R. Krainer et al. profile →
  7. Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2
    1992 642 citations Akila Mayeda, Adrian R. Krainer profile →
  8. Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro
    1984 615 citations Adrian R. Krainer et al. profile →
  9. Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1
    2002 578 citations Luca Cartegni, Adrian R. Krainer profile →
  10. Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
    2011 556 citations Yimin Hua, Kentaro Sahashi et al. Nature profile →
  11. Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors
    1994 536 citations Javier F. Cáceres, Adrian R. Krainer et al. Science profile →
  12. Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
    2010 501 citations Yimin Hua, Kentaro Sahashi et al. Genes & Development profile →
  13. Antisense Oligonucleotide Therapies for Neurodegenerative Diseases
    2019 242 citations C. Frank Bennett, Adrian R. Krainer et al. Annual Review of Neuroscience profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Adrian R. Krainer United States 86 24.9k 4.3k 2.4k 2.1k 1.5k 179 28.0k
Francisco E. Baralle Italy 71 12.0k 0.5× 4.7k 1.1× 1.7k 0.7× 1.3k 0.6× 796 0.5× 249 20.7k
G Yeo United States 81 20.6k 0.8× 1.7k 0.4× 4.3k 1.8× 2.5k 1.2× 570 0.4× 239 25.2k
Frank Grosveld Netherlands 105 27.5k 1.1× 3.8k 0.9× 2.3k 0.9× 7.1k 3.4× 815 0.6× 391 38.5k
Gordon Keller United States 87 22.2k 0.9× 2.6k 0.6× 1.4k 0.6× 3.0k 1.4× 1.3k 0.9× 229 30.9k
Larry Kedes United States 71 13.5k 0.5× 810 0.2× 1.3k 0.5× 2.6k 1.2× 2.5k 1.7× 174 18.1k
Yi Zheng United States 83 14.1k 0.6× 1.1k 0.2× 1.6k 0.7× 1.4k 0.6× 507 0.3× 364 21.5k
David A. Guertin United States 39 14.8k 0.6× 1000 0.2× 2.2k 0.9× 938 0.4× 641 0.4× 63 21.2k
Jeffrey L. Wrana Canada 103 35.2k 1.4× 1.6k 0.4× 4.7k 1.9× 3.3k 1.5× 785 0.5× 270 44.9k
Richard Treisman United Kingdom 70 19.1k 0.8× 710 0.2× 2.5k 1.0× 3.2k 1.5× 1.1k 0.8× 116 25.1k
Ron Stewart United States 44 18.9k 0.8× 1.3k 0.3× 1.8k 0.7× 2.5k 1.2× 193 0.1× 101 21.9k

Countries citing papers authored by Adrian R. Krainer

Since Specialization
Citations

This map shows the geographic impact of Adrian R. Krainer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Adrian R. Krainer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Adrian R. Krainer more than expected).

Fields of papers citing papers by Adrian R. Krainer

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Adrian R. Krainer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Adrian R. Krainer. The network helps show where Adrian R. Krainer may publish in the future.

Co-authorship network of co-authors of Adrian R. Krainer

This figure shows the co-authorship network connecting the top 25 collaborators of Adrian R. Krainer. A scholar is included among the top collaborators of Adrian R. Krainer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Adrian R. Krainer. Adrian R. Krainer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Ajiro, Masahiko, Tomonari Awaya, Kei Iida, et al.. (2021). Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia. Nature Communications. 12(1). 4507–4507. 25 indexed citations
2.
Bennett, C. Frank, Adrian R. Krainer, & Don W. Cleveland. (2019). Antisense Oligonucleotide Therapies for Neurodegenerative Diseases. Annual Review of Neuroscience. 42(1). 385–406. 242 indexed citations breakdown →
3.
Jangi, Mohini, Christina Fleet, Patrick Cullen, et al.. (2017). SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage. Proceedings of the National Academy of Sciences. 114(12). E2347–E2356. 91 indexed citations
4.
Krainer, Adrian R.. (2015). Splicing: still so much to learn. RNA. 21(4). 500–501. 1 indexed citations
5.
Xiong, Hui, Babak Alipanahi, Leo J. Lee, et al.. (2014). The human splicing code reveals new insights into the genetic determinants of disease. Science. 347(6218). 1254806–1254806. 829 indexed citations breakdown →
6.
Kole, Ryszard, Adrian R. Krainer, & Sidney Altman. (2012). RNA therapeutics: beyond RNA interference and antisense oligonucleotides. Nature Reviews Drug Discovery. 11(2). 125–140. 916 indexed citations breakdown →
7.
Rigo, Frank, Yimin Hua, Seung Chun, et al.. (2012). Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing. Nature Chemical Biology. 8(6). 555–561. 89 indexed citations
8.
Anczuków, Olga, Avi Z. Rosenberg, Martin Akerman, et al.. (2012). The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation. Nature Structural & Molecular Biology. 19(2). 220–228. 330 indexed citations
9.
Hua, Yimin, Kentaro Sahashi, Frank Rigo, et al.. (2011). Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model. Nature. 478(7367). 123–126. 556 indexed citations breakdown →
10.
Sun, Shuying, Zuo‐Feng Zhang, Oliver I. Fregoso, & Adrian R. Krainer. (2011). Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2. RNA. 18(2). 274–283. 78 indexed citations
11.
Wu, Han, Shuying Sun, Kang Tu, et al.. (2010). A Splicing-Independent Function of SF2/ASF in MicroRNA Processing. Molecular Cell. 38(1). 67–77. 161 indexed citations
12.
Zhang, Chaolin, Zuo‐Feng Zhang, John C. Castle, et al.. (2008). Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2 (Genes and Development (2008) 22 (2550-2563)). Genes & Development. 22(20). 46 indexed citations
13.
Khoo, Bernard, Xavier Roca, Shern L. Chew, & Adrian R. Krainer. (2007). Antisense oligonucleotide-induced alternative splicing of the APOB mRNA generates a novel isoform of APOB. Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory). 5 indexed citations
14.
Kimurâ, Hiroshi, Nanako Takizawa, Eric Allemand, et al.. (2006). A novel histone exchange factor, protein phosphatase 2Cγ, mediates the exchange and dephosphorylation of H2A–H2B. The Journal of Cell Biology. 175(3). 389–400. 70 indexed citations
15.
Wang, Yibin, et al.. (2003). Human Immunodeficiency Virus Type 1 hnRNP A/B-Dependent Exonic Splicing Silencer ESSV Antagonizes Binding of U2AF65 to Viral Polypyrimidine Tracts. Molecular and Cellular Biology. 23(23). 8762–8772. 58 indexed citations
16.
Mayeda, Akila & Adrian R. Krainer. (2003). Preparation of Hela Cell Nuclear and Cytosolic S100 Extracts for In Vitro Splicing. Humana Press eBooks. 118. 309–314. 79 indexed citations
17.
Cazalla, Demián, Jun Zhu, Lisa Manche, et al.. (2002). Nuclear Export and Retention Signals in the RS Domain of SR Proteins. Molecular and Cellular Biology. 22(19). 6871–6882. 142 indexed citations
18.
Hastings, Michelle L. & Adrian R. Krainer. (2001). Functions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway. RNA. 7(3). 471–482. 53 indexed citations
19.
Eperon, Ian C., Olga V. Makarova, Akila Mayeda, et al.. (2000). Selection of Alternative 5′ Splice Sites: Role of U1 snRNP and Models for the Antagonistic Effects of SF2/ASF and hnRNP A1. Molecular and Cellular Biology. 20(22). 8303–8318. 158 indexed citations
20.
Liu, Hongxiang, Shern L. Chew, Luca Cartegni, Michael Q. Zhang, & Adrian R. Krainer. (2000). Exonic Splicing Enhancer Motif Recognized by Human SC35 under Splicing Conditions. Molecular and Cellular Biology. 20(3). 1063–1071. 190 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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