Christopher E. Hart

1.6k citations

28 papers · 1.1k indexed · h-index 14

Impact in

Molecular Biology top 10%
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- DNA and Nucleic Acid Chemistry
- RNA Research and Splicing
- RNA and protein synthesis mechanisms
- CRISPR and Genetic Engineering
- RNA modifications and cancer
- Genomics and Chromatin Dynamics
Nephrology top 10%

Papers in ⓘ

Molecular Biology 23
- CRISPR and Genetic Engineering 5
- Bioinformatics and Genomic Networks 5
- Gene expression and cancer classification 5
- Advanced biosensing and bioanalysis techniques 4
- RNA Research and Splicing 3
- RNA Interference and Gene Delivery 3
- DNA and Nucleic Acid Chemistry 3
- Gene Regulatory Network Analysis 3
Neurology 2

Co-authors: Stanley T. Crooke (5 shared papers)Xue‐hai Liang (3 shared papers)Punit P. Seth (3 shared papers)Cheryl Li De Hoyos (2 shared papers)Michael T. Migawa (2 shared papers)Eric E. Swayze (4 shared papers)Sagar Damle (7 shared papers)Gene Hung (2 shared papers)
Journals: Nucleic Acids Research (4 papers)Molecular Therapy (1 paper)Journal of Neurodevelopmental Disorders (1 paper)PLANT PHYSIOLOGY (1 paper)Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms (1 paper)
Partner nations: United States France Finland

In The Last Decade

Christopher E. Hart

26 papers receiving 1.1k citations

Peers

Countries citing papers authored by Christopher E. Hart

Since Specialization

Citations

This map shows the geographic impact of Christopher E. Hart's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher E. Hart with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher E. Hart more than expected).

Fields of papers citing papers by Christopher E. Hart

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher E. Hart. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher E. Hart. The network helps show where Christopher E. Hart may publish in the future.

Co-authors

The 25 scholars most cited alongside Christopher E. Hart, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher E. Hart Line = papers co-authored together Christopher E. Hart links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 28 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index Nature Biotechnology ·Wen Shen, Cheryl Li De Hoyos, Michael T. Migawa, Timothy A. Vickers, Hong Sun, Audrey Low, Thomas A. Bell, Meghdad Rahdar, Swagatam Mukhopadhyay, Christopher E. Hart, Melanie Bell, Stan Riney, Susan Murray, Sarah Greenlee, Rosanne M. Crooke, Xue‐hai Liang, Punit P. Seth, Stanley T. Crooke	2019	239
2	Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts Nucleic Acids Research ·Sebastien A. Burel, Christopher E. Hart, Patrick Cauntay, Jill Hsiao, Todd Machemer, Melanie Katz, Andy Watt, Huynh‐Hoa Bui, Husam S. Younis, Mahyar Sabripour, Susan M. Freier, Gene Hung, Amy Dan, Thazha P. Prakash, Punit P. Seth, Eric E. Swayze, C. Frank Bennett, Stanley T. Crooke, Scott P. Henry	2015	148
3	Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers Molecular Therapy ·Stanley T. Crooke, Brenda F. Baker, T. Jesse Kwoh, Wei Cheng, Dan J Schulz, Shuting Xia, Nelson R. Salgado, Huynh‐Hoa Bui, Christopher E. Hart, Sebastien A. Burel, Husam S. Younis, Richard S. Geary, Scott P. Henry, Sanjay Bhanot	2016	93
4	Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages Nucleic Acids Research ·Wei Wan, Michael T. Migawa, Guillermo Vasquez, Heather Murray, Josh G. Nichols, Hans Gaus, Andrés Berdeja, Sam Lee, Christopher E. Hart, Walt F. Lima, Eric E. Swayze, Punit P. Seth	2014	93
5	Dynamic and complex transcription factor binding during an inducible response in yeast Genes & Development ·Li Ni, Can Bruce, Christopher E. Hart, Justine Leigh-Bell, Daniel Gelperin, Lara Umansky, Mark Gerstein, M Snyder	2009	85
6	ViableRNaseH1knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function Nucleic Acids Research ·Walt F. Lima, Heather Murray, Sagar Damle, Christopher E. Hart, Gene Hung, Cheryl Li De Hoyos, Xue‐hai Liang, Stanley T. Crooke	2016	84
7	Genome-wide identification and characterization of replication origins by deep sequencing Genome biology ·Jia Xu, Yoshimi Yanagisawa, Alexander M. Tsankov, Christopher E. Hart, Keita Aoki, Naveen Kommajosyula, Kathleen E. Steinmann, James Bochicchio, Carsten Russ, Aviv Regev, Oliver J. Rando, Chad Nusbaum, Hironori Niki, Patrice M. Milos, Zhiping Weng, Nick Rhind	2012	74
8	Antisense oligonucleotide treatment ameliorates IFN-γ–induced proteinuria in APOL1-transgenic mice JCI Insight ·Mariam Aghajan, Sheri Booten, Magnus Althage, Christopher E. Hart, Anette Ericsson, Ingela Maxvall, Joseph Ochaba, Angela Menschik-Lundin, Judith Hartleib, Steven Kuntz, Danielle Gattis, Christine Ahlström, Andrew T. Watt, Jeffery A. Engelhardt, Brett P. Monia, Maria Chiara Magnone, Shuling Guo	2019	69
9	Mining gene expression data by interpreting principal components BMC Bioinformatics ·J. Roden, Brandon W King, Diane Trout, A Mortazavi, B Wold, Christopher E. Hart	2006	46
10	Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms ·Xue‐hai Liang, Christopher E. Hart, Stanley T. Crooke	2013	39
11	Single-Molecule Sequencing Methods in enzymology on CD-ROM/Methods in enzymology ·Christopher E. Hart, Doron Lipson, Fatih Ozsolak, Tal Raz, Kathleen E. Steinmann, John F. Thompson, Patrice M. Milos	2010	27
12	Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration PLoS ONE ·Lulu Huang, Sagar Damle, Sheri Booten, Priyam Singh, Mahyar Sabripour, Jeff Hsu, Minji Jo, Melanie Katz, Andy Watt, Christopher E. Hart, Susan M. Freier, Brett P. Monia, Shuling Guo	2015	26
13	Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite–induced Goblet Cell Metaplasia in the Adult Murine Lung American Journal of Respiratory Cell and Molecular Biology ·Michele Carrer, Jeff Crosby, Guizhen Sun, Chenguang Zhao, Sagar Damle, Steven Kuntz, Brett P. Monia, Christopher E. Hart, Tamar R. Grossman	2020	25
14	A modular analysis of microglia gene expression, insights into the aged phenotype BMC Genomics ·Christine E. Cho, Sagar Damle, Edward V. Wancewicz, Swagatam Mukhopadhyay, Christopher E. Hart, Curt Mazur, Eric E. Swayze, Fredrik Kamme	2019	23
15	Connectivity in the Yeast Cell Cycle Transcription Network: Inferences from Neural Networks PLoS Computational Biology ·Christopher E. Hart, Eric Mjolsness, B Wold	2006	13
16	HELM Software for Biopolymers Journal of Chemical Information and Modeling ·Jeff Milton, Tianhong Zhang, Claire Bellamy, Eric E. Swayze, Christopher E. Hart, Markus Weisser, Sabrina Hecht, Sergio H. Rotstein	2017	12
17	A mathematical and computational framework for quantitative comparison and integration of large-scale gene expression data Nucleic Acids Research ·Christopher E. Hart	2005	10
18	Bayesian Quadrature for Ratios International Conference on Artificial Intelligence and Statistics ·Michael A. Osborne, Roman Garnett, Stephen Roberts, Christopher E. Hart, S. Aigrain, Neale P. Gibson	2012	8
19	Gene Expression Clustering with Functional Mixture Models CaltechAUTHORS (California Institute of Technology) ·Darya Chudova, Christopher E. Hart, Eric Mjolsness, Padhraic Smyth	2003	7
20	The Cell Wall Arabinose-Deficient Arabidopsis thaliana Mutant murus5 Encodes a Defective Allele of REVERSIBLY GLYCOSYLATED POLYPEPTIDE2 PLANT PHYSIOLOGY ·Christopher K. Dugard, Rachel A. Mertz, Catherine Rayon, Davide Mercadante, Christopher E. Hart, Matheus R. Benatti, Anna T. Olek, Phillip SanMiguel, Bruce R. Cooper, Wolf‐Dieter Reiter, Maureen C. McCann, Nicholas C. Carpita	2016	6

About Christopher E. Hart

Christopher E. Hart is a scholar working on Molecular Biology, Neurology, Developmental Neuroscience, Cancer Research and Statistical and Nonlinear Physics, having authored 28 papers that have together received 1.1k indexed citations. Recurring topics across this work include CRISPR and Genetic Engineering (5 papers), Bioinformatics and Genomic Networks (5 papers), Gene expression and cancer classification (5 papers), Advanced biosensing and bioanalysis techniques (4 papers), RNA Research and Splicing (3 papers), RNA Interference and Gene Delivery (3 papers), DNA and Nucleic Acid Chemistry (3 papers) and Gene Regulatory Network Analysis (3 papers). The work is most often cited by research in Molecular Biology (966 citations), Nephrology (58 citations), Cancer Research (113 citations), Genetics (72 citations) and Genetics (80 citations). Christopher E. Hart has collaborated with scholars based in United States, France and Finland. Frequent co-authors include Stanley T. Crooke, Xue‐hai Liang, Punit P. Seth, Cheryl Li De Hoyos, Michael T. Migawa, Eric E. Swayze, Sagar Damle, Gene Hung, Walt F. Lima and Heather Murray. Their work appears in journals such as Nucleic Acids Research, Molecular Therapy, Journal of Neurodevelopmental Disorders, PLANT PHYSIOLOGY and Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact