Inge Grundke‐Iqbal

38.9k total citations · 11 hit papers
280 papers, 31.7k citations indexed

About

Inge Grundke‐Iqbal is a scholar working on Physiology, Molecular Biology and Cell Biology. According to data from OpenAlex, Inge Grundke‐Iqbal has authored 280 papers receiving a total of 31.7k indexed citations (citations by other indexed papers that have themselves been cited), including 198 papers in Physiology, 165 papers in Molecular Biology and 81 papers in Cell Biology. Recurrent topics in Inge Grundke‐Iqbal's work include Alzheimer's disease research and treatments (193 papers), Microtubule and mitosis dynamics (54 papers) and Mitochondrial Function and Pathology (41 papers). Inge Grundke‐Iqbal is often cited by papers focused on Alzheimer's disease research and treatments (193 papers), Microtubule and mitosis dynamics (54 papers) and Mitochondrial Function and Pathology (41 papers). Inge Grundke‐Iqbal collaborates with scholars based in United States, China and Sweden. Inge Grundke‐Iqbal's co-authors include Khalid Iqbal, Cheng‐Xin Gong, Y C Tung, Fei Liu, H. M. Wiśniewski, Khalid Iqbal, Khurshid Iqbal, Tanweer Zaidi, Alejandra del C. Alonso and Lester I. Binder and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and Nucleic Acids Research.

In The Last Decade

Inge Grundke‐Iqbal

277 papers receiving 30.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

1986 2.9k citations Inge Grundke‐Iqbal, H. M. Wiśniewski et al. Proceedings of the National Academy of Sciences profile →
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

1986 1.4k citations Inge Grundke‐Iqbal, Khalid Iqbal et al. Journal of Biological Chemistry profile →
Tau in Alzheimer Disease and Related Tauopathies

2010 794 citations Khalid Iqbal, F. Liu et al. Current Alzheimer Research profile →
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments

2001 763 citations Alejandra del C. Alonso, Tanweer Zaidi et al. Proceedings of the National Academy of Sciences profile →
Tau pathology in Alzheimer disease and other tauopathies

2004 759 citations Khalid Iqbal, Alejandra del C. Alonso et al. profile →
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules

1996 702 citations Inge Grundke‐Iqbal, Khalid Iqbal et al. profile →
Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease

1989 677 citations C. Bancher, Inge Grundke‐Iqbal et al. profile →
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

2005 624 citations Fei Liu, Inge Grundke‐Iqbal et al. European Journal of Neuroscience profile →
O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease

2004 616 citations Fei Liu, Khalid Iqbal et al. Proceedings of the National Academy of Sciences profile →
Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease.

1994 600 citations Tanweer Zaidi, Inge Grundke‐Iqbal et al. Proceedings of the National Academy of Sciences profile →
Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease.

1993 587 citations Khalid Iqbal, Inge Grundke‐Iqbal et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Inge Grundke‐Iqbal United States	89	21.7k	15.2k	7.5k	4.9k	4.9k	280	31.7k
Khalid Iqbal United States	95	21.9k 1.0×	15.0k 1.0×	7.6k 1.0×	5.1k 1.0×	5.2k 1.1×	375	32.8k
Sangram S. Sisodia United States	91	20.9k 1.0×	15.8k 1.0×	8.4k 1.1×	5.5k 1.1×	4.6k 0.9×	240	33.5k
Takaomi C. Saido Japan	98	19.6k 0.9×	16.3k 1.1×	8.2k 1.1×	4.5k 0.9×	6.6k 1.4×	504	36.1k
Karen Duff United States	89	18.0k 0.8×	10.9k 0.7×	9.6k 1.3×	4.1k 0.8×	5.2k 1.1×	236	29.5k
Konrad Beyreuther Germany	98	27.0k 1.2×	21.0k 1.4×	6.5k 0.9×	5.8k 1.2×	4.1k 0.8×	439	40.9k
Frank M. LaFerla United States	97	23.2k 1.1×	13.1k 0.9×	10.1k 1.3×	6.3k 1.3×	8.0k 1.6×	248	36.7k
Todd E. Golde United States	94	18.8k 0.9×	14.2k 0.9×	5.7k 0.8×	5.3k 1.1×	5.4k 1.1×	314	32.1k
Jesús Ávila Spain	95	13.9k 0.6×	16.1k 1.1×	10.1k 1.3×	3.7k 0.8×	4.4k 0.9×	650	33.7k
Eva‐Maria Mandelkow Germany	79	14.0k 0.6×	11.5k 0.8×	5.7k 0.8×	3.1k 0.6×	3.1k 0.6×	196	23.0k
Peter St George‐Hyslop Canada	83	16.8k 0.8×	12.1k 0.8×	5.3k 0.7×	3.7k 0.8×	3.7k 0.8×	391	28.3k

Countries citing papers authored by Inge Grundke‐Iqbal

Since Specialization

Citations

This map shows the geographic impact of Inge Grundke‐Iqbal's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Inge Grundke‐Iqbal with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Inge Grundke‐Iqbal more than expected).

Fields of papers citing papers by Inge Grundke‐Iqbal

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Inge Grundke‐Iqbal. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Inge Grundke‐Iqbal. The network helps show where Inge Grundke‐Iqbal may publish in the future.

Co-authorship network of co-authors of Inge Grundke‐Iqbal

This figure shows the co-authorship network connecting the top 25 collaborators of Inge Grundke‐Iqbal. A scholar is included among the top collaborators of Inge Grundke‐Iqbal based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Inge Grundke‐Iqbal. Inge Grundke‐Iqbal is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Yin, Xiaomin, Nana Jin, Jianlan Gu, et al.. (2012). Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A) Modulates Serine/Arginine-rich Protein 55 (SRp55)-promoted Tau Exon 10 Inclusion. Journal of Biological Chemistry. 287(36). 30497–30506. 79 indexed citations

Iqbal, Khalid & Inge Grundke‐Iqbal. (2011). Opportunities and challenges in developing Alzheimer disease therapeutics. Acta Neuropathologica. 122(5). 543–549. 42 indexed citations

Liu, Ying, Fei Liu, Inge Grundke‐Iqbal, Khalid Iqbal, & Cheng‐Xin Gong. (2009). Brain glucose transporters, O‐GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer’s disease. Journal of Neurochemistry. 111(1). 242–249. 160 indexed citations

Liu, F., Jianhua Shi, Hitoshi Tanimukai, et al.. (2009). Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease. Brain. 132(7). 1820–1832. 340 indexed citations

Alonso, Alejandra del C., Ben Li, Inge Grundke‐Iqbal, & Khalid Iqbal. (2008). Mechanism of Tau-Induced Neurodegeneration in Alzheimer Disease and Related Tauopathies. Current Alzheimer Research. 5(4). 375–384. 101 indexed citations

Li, Bin, Hidenaga Yamamori, Yoshitaka Tatebayashi, et al.. (2008). Failure of Neuronal Maturation in Alzheimer Disease Dentate Gyrus. Journal of Neuropathology & Experimental Neurology. 67(1). 78–84. 197 indexed citations

Ruben, George C., et al.. (2005). Paired helical filaments (PHFs) are a family of single filament structures with a common helical turn period: Negatively stained PHF imaged by TEM and measured before and after sonication, deglycosylation, and dephosphorylation. Microscopy Research and Technique. 67(3-4). 175–195. 22 indexed citations

Rahman, Abdur, Inge Grundke‐Iqbal, & Khalid Iqbal. (2005). Phosphothreonine-212 of Alzheimer Abnormally Hyperphosphorylated Tau is a Preferred Substrate of Protein Phosphatase-1. Neurochemical Research. 30(2). 277–287. 40 indexed citations

Liu, Fei, Khalid Iqbal, Inge Grundke‐Iqbal, Gerald W. Hart, & Cheng-Xin Gong. (2004). O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease. Proceedings of the National Academy of Sciences. 101(29). 10804–10809. 616 indexed citations breakdown →

10.

Huang, Yu, Hitoshi Tanimukai, Fei Liu, et al.. (2004). Elevation of the level and activity of acid ceramidase in Alzheimer's disease brain. European Journal of Neuroscience. 20(12). 3489–3497. 49 indexed citations

11.

Liu, Fei, Khalid Iqbal, Inge Grundke‐Iqbal, Sandra Rossie, & Cheng‐Xin Gong. (2004). Dephosphorylation of Tau by Protein Phosphatase 5. Journal of Biological Chemistry. 280(3). 1790–1796. 106 indexed citations

12.

Hu, Yuanyuan, Xiaochuang Wang, Qiuhong Duan, et al.. (2002). Elevated levels of phosphorylated neurofilament proteins in cerebrospinal fluid of Alzheimer disease patients. Neuroscience Letters. 320(3). 156–160. 89 indexed citations

13.

Alonso, Alejandra del C., Tanweer Zaidi, Michal Novák, et al.. (2001). Interaction of Tau Isoforms with Alzheimer's Disease Abnormally Hyperphosphorylated Tau and in VitroPhosphorylation into the Disease-like Protein. Journal of Biological Chemistry. 276(41). 37967–37973. 133 indexed citations

14.

Liu, Fei, Tanweer Zaidi, Khalid Iqbal, Inge Grundke‐Iqbal, & Cheng‐Xin Gong. (2000). Glycosylation of tau protein occurs earlier than its hyperphosphorylation in Alzheimer's disease. Neurobiology of Aging. 21. 16–16. 2 indexed citations

15.

Sengupta, Amitabha, Juraj Kabát, Michal Novák, et al.. (1998). Phosphorylation of Tau at Both Thr 231 and Ser 262 Is Required for Maximal Inhibition of Its Binding to Microtubules. Archives of Biochemistry and Biophysics. 357(2). 299–309. 283 indexed citations

16.

Khatoon, Sabiha, Inge Grundke‐Iqbal, & Khalid Iqbal. (1994). Levels of normal and abnormally phosphorylated tau in different cellular and regional compartments of Alzheimer disease and control brains. FEBS Letters. 351(1). 80–84. 142 indexed citations

17.

Barcikowska, Maria, H. M. Wiśniewski, C. Bancher, & Inge Grundke‐Iqbal. (1989). About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation. Acta Neuropathologica. 78(3). 225–231. 92 indexed citations

18.

Galloway, Pamela G., Inge Grundke‐Iqbal, Khalid Iqbal, & George Perry. (1988). Lewy Bodies Contain Epitopes Both Shared and Distinct from Alzheimer Neurofibrillary Tangles. Journal of Neuropathology & Experimental Neurology. 47(6). 654–663. 114 indexed citations

19.

Iqbal, Khalid, et al.. (1987). Alzheimer??s disease, microtubule and neurofilament proteins, and axoplasmic flow. Alzheimer Disease & Associated Disorders. 1(3). 202–202. 5 indexed citations

20.

Grundke‐Iqbal, Inge & Murray B. Bornstein. (1977). ARE DEMYELINATING SERUM FACTORS IN MS AND EAE GAMMA GLOBULINS?. Journal of Neuropathology & Experimental Neurology. 36(3). 602–602. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact