Jacek Biernat

24.3k total citations · 8 hit papers
111 papers, 19.1k citations indexed

About

Jacek Biernat is a scholar working on Physiology, Molecular Biology and Cell Biology. According to data from OpenAlex, Jacek Biernat has authored 111 papers receiving a total of 19.1k indexed citations (citations by other indexed papers that have themselves been cited), including 79 papers in Physiology, 76 papers in Molecular Biology and 46 papers in Cell Biology. Recurrent topics in Jacek Biernat's work include Alzheimer's disease research and treatments (79 papers), Microtubule and mitosis dynamics (43 papers) and Protein Structure and Dynamics (28 papers). Jacek Biernat is often cited by papers focused on Alzheimer's disease research and treatments (79 papers), Microtubule and mitosis dynamics (43 papers) and Protein Structure and Dynamics (28 papers). Jacek Biernat collaborates with scholars based in Germany, United States and France. Jacek Biernat's co-authors include Eckhard Mandelkow�, Eva‐Maria Mandelkow, Martin von Bergen�, Markus Zweckstetter, Gerard Drewes, N. Gustke, Bernhard Trinczek, Stefan Barghorn, Christian Griesinger and Peter Friedhoff and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Jacek Biernat

111 papers receiving 18.8k citations

Hit Papers

Assembly of τ protein into Alzheimer paired helical filam... 1993 2026 2004 2015 2000 2001 1993 2017 1994 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif ( 306 VQIVYK 311 ) forming β structure
    2000 805 citations Martin von Bergen�, Peter Friedhoff et al. profile →
  2. Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease
    2001 635 citations Sophie Leclerc, Matthieu Garnier et al. Journal of Biological Chemistry profile →
  3. Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
    1993 633 citations Jacek Biernat, N. Gustke et al. Neuron profile →
  4. Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau
    2017 569 citations Susmitha Ambadipudi, Jacek Biernat et al. Nature Communications profile →
  5. Domains of tau Protein and Interactions with Microtubules
    1994 530 citations N. Gustke, Bernhard Trinczek et al. profile →
  6. Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
    2009 511 citations Stefan Bibow, Sadasivam Jeganathan� et al. profile →
  7. Tau stabilizes microtubules by binding at the interface between tubulin heterodimers
    2015 394 citations Jacek Biernat, Satish Kumar et al. profile →
  8. A current view on Tau protein phosphorylation in Alzheimer's disease
    2021 288 citations Susanne Wegmann, Jacek Biernat et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jacek Biernat Germany 74 11.5k 11.2k 4.3k 4.0k 2.3k 111 19.1k
Eva‐Maria Mandelkow Germany 79 14.0k 1.2× 11.5k 1.0× 5.6k 1.3× 5.7k 1.4× 3.1k 1.3× 196 23.0k
Charles Glabe United States 85 19.1k 1.7× 13.6k 1.2× 2.6k 0.6× 4.2k 1.0× 4.0k 1.7× 195 28.2k
Gerd Multhaup Germany 78 18.5k 1.6× 13.3k 1.2× 2.1k 0.5× 3.7k 0.9× 4.0k 1.7× 180 27.0k
Eckhard Mandelkow� Germany 100 17.9k 1.6× 18.5k 1.7× 8.9k 2.1× 6.5k 1.6× 3.6k 1.5× 276 32.7k
Taisuke Tomita Japan 58 8.6k 0.7× 6.2k 0.6× 2.0k 0.5× 3.3k 0.8× 2.4k 1.0× 218 13.9k
Rakez Kayed United States 64 16.9k 1.5× 11.0k 1.0× 2.0k 0.5× 4.8k 1.2× 3.6k 1.5× 203 23.8k
Lester I. Binder United States 72 13.1k 1.1× 9.6k 0.9× 4.6k 1.1× 5.9k 1.5× 2.7k 1.1× 133 19.9k
Karl H. Weisgraber United States 87 9.3k 0.8× 12.5k 1.1× 1.8k 0.4× 2.8k 0.7× 1.7k 0.7× 237 28.3k
Claudio Soto United States 79 8.4k 0.7× 13.4k 1.2× 1.8k 0.4× 1.8k 0.5× 2.3k 1.0× 239 21.5k
David B. Teplow United States 93 20.6k 1.8× 20.2k 1.8× 2.6k 0.6× 3.4k 0.9× 4.9k 2.1× 217 33.1k

Countries citing papers authored by Jacek Biernat

Since Specialization
Citations

This map shows the geographic impact of Jacek Biernat's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jacek Biernat with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jacek Biernat more than expected).

Fields of papers citing papers by Jacek Biernat

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jacek Biernat. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jacek Biernat. The network helps show where Jacek Biernat may publish in the future.

Co-authorship network of co-authors of Jacek Biernat

This figure shows the co-authorship network connecting the top 25 collaborators of Jacek Biernat. A scholar is included among the top collaborators of Jacek Biernat based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jacek Biernat. Jacek Biernat is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Biernat, Jacek, et al.. (2018). Lipid Membrane Templated Misfolding and Self-Assembly of Intrinsically Disordered Tau Protein. Biophysical Journal. 114(3). 616a–616a. 2 indexed citations
2.
Pickhardt, Marcus, Jacek Biernat, Frank J.A. Dennissen, et al.. (2017). Time course of Tau toxicity and pharmacologic prevention in a cell model of Tauopathy. Neurobiology of Aging. 57. 47–63. 16 indexed citations
3.
Ambadipudi, Susmitha, Jacek Biernat, Dietmar Riedel, Eckhard Mandelkow�, & Markus Zweckstetter. (2017). Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau. Nature Communications. 8(1). 275–275. 569 indexed citations breakdown →
4.
Karagöz, G Elif, Afonso M.S. Duarte, Elias Akoury, et al.. (2014). Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action. Cell. 156(5). 963–974. 241 indexed citations
5.
Tepper, Katharina, Jacek Biernat, Satish Kumar, et al.. (2014). Oligomer Formation of Tau Protein Hyperphosphorylated in Cells. Journal of Biological Chemistry. 289(49). 34389–34407. 123 indexed citations
6.
Kumar, Satish, Katharina Tepper, Senthilvelrajan Kaniyappan, et al.. (2014). Stages and Conformations of the Tau Repeat Domain during Aggregation and Its Effect on Neuronal Toxicity. Journal of Biological Chemistry. 289(29). 20318–20332. 67 indexed citations
7.
Schwalbe, M., Valéry Ozenne, Stefan Bibow, et al.. (2013). Predictive Atomic Resolution Descriptions of Intrinsically Disordered hTau40 and α-Synuclein in Solution from NMR and Small Angle Scattering. Structure. 22(2). 238–249. 156 indexed citations
8.
Vijayan, Vinesh, Jean‐Philippe Demers, Jacek Biernat, et al.. (2009). Low‐Power Solid‐State NMR Experiments for Resonance Assignment under Fast Magic‐Angle Spinning. ChemPhysChem. 10(13). 2205–2208. 40 indexed citations
9.
Jeganathan�, Sadasivam, Antje Hascher, Subashchandrabose Chinnathambi, et al.. (2008). Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation. Journal of Biological Chemistry. 283(46). 32066–32076. 205 indexed citations
10.
Goldsbury, Claire, Maria‐Magdalena Mocanu, Edda Thies, et al.. (2006). Inhibition of APP Trafficking by Tau Protein Does Not Increase the Generation of Amyloid‐β Peptides. Traffic. 7(7). 873–888. 68 indexed citations
11.
Khlistunova, Inna, Jacek Biernat, Yipeng Wang, et al.. (2005). Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy. Journal of Biological Chemistry. 281(2). 1205–1214. 287 indexed citations
12.
Mandelkow, Eva‐Maria, et al.. (2004). MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons. The Journal of Cell Biology. 167(1). 99–110. 186 indexed citations
13.
Bergen�, Martin von, Stefan Barghorn, Jacek Biernat, Eva‐Maria Mandelkow, & Eckhard Mandelkow�. (2004). Tau aggregation is driven by a transition from random coil to beta sheet structure. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1739(2-3). 158–166. 297 indexed citations
14.
Leclerc, Sophie, Matthieu Garnier, Doris Marko, et al.. (2001). Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease. Journal of Biological Chemistry. 276(1). 251–260. 635 indexed citations breakdown →
15.
16.
Godemann, Robert, Jacek Biernat, Eva‐Maria Mandelkow, & Eckhard Mandelkow�. (1999). Phosphorylation of tau protein by recombinant GSK‐3β: pronounced phosphorylation at select Ser/Thr‐Pro motifs but no phosphorylation at Ser262 in the repeat domain. FEBS Letters. 454(1-2). 157–164. 96 indexed citations
17.
Illenberger, Susanne, Gerard Drewes, Bernhard Trinczek, et al.. (1996). Phosphorylation of Microtubule-associated Proteins MAP2 and MAP4 by the Protein Kinase p110mark. Journal of Biological Chemistry. 271(18). 10834–10843. 158 indexed citations
18.
Friedhoff, Peter, et al.. (1996). RNA stimulates aggregation of microtubule‐associated protein tau into Alzheimer‐like paired helical filaments. FEBS Letters. 399(3). 344–349. 427 indexed citations
19.
Mandelkow, Eva‐Maria, Jacek Biernat, Gerard Drewes, N. Gustke, & Bernhard Trinczek. (1995). Tau domains, phosphorylation, and interactions with microtubules. Neurobiology of Aging. 16(3). 355–362. 248 indexed citations
20.
Biernat, Jacek, N. Gustke, Gerard Drewes, Eva‐Maria Mandelkow, & Eckhard Mandelkow�. (1993). Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding. Neuron. 11(1). 153–163. 633 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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