Jacek Biernat

24.3k total citations · 8 hit papers
111 papers, 19.1k citations indexed

About

Jacek Biernat is a scholar working on Physiology, Molecular Biology and Cell Biology. According to data from OpenAlex, Jacek Biernat has authored 111 papers receiving a total of 19.1k indexed citations (citations by other indexed papers that have themselves been cited), including 79 papers in Physiology, 76 papers in Molecular Biology and 46 papers in Cell Biology. Recurrent topics in Jacek Biernat's work include Alzheimer's disease research and treatments (79 papers), Microtubule and mitosis dynamics (43 papers) and Protein Structure and Dynamics (28 papers). Jacek Biernat is often cited by papers focused on Alzheimer's disease research and treatments (79 papers), Microtubule and mitosis dynamics (43 papers) and Protein Structure and Dynamics (28 papers). Jacek Biernat collaborates with scholars based in Germany, United States and France. Jacek Biernat's co-authors include Eckhard Mandelkow�, Eva‐Maria Mandelkow, Martin von Bergen�, Markus Zweckstetter, Gerard Drewes, N. Gustke, Bernhard Trinczek, Stefan Barghorn, Christian Griesinger and Peter Friedhoff and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Jacek Biernat

111 papers receiving 18.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif ( ³⁰⁶ VQIVYK ³¹¹ ) forming β structure

2000 805 citations Martin von Bergen�, Peter Friedhoff et al. profile →
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease

2001 635 citations Sophie Leclerc, Matthieu Garnier et al. Journal of Biological Chemistry profile →
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding

1993 633 citations Jacek Biernat, N. Gustke et al. Neuron profile →
Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau

2017 569 citations Susmitha Ambadipudi, Jacek Biernat et al. Nature Communications profile →
Domains of tau Protein and Interactions with Microtubules

1994 530 citations N. Gustke, Bernhard Trinczek et al. profile →
Structural Polymorphism of 441-Residue Tau at Single Residue Resolution

2009 511 citations Stefan Bibow, Sadasivam Jeganathan� et al. profile →
Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

2015 394 citations Jacek Biernat, Satish Kumar et al. profile →
A current view on Tau protein phosphorylation in Alzheimer's disease

2021 288 citations Susanne Wegmann, Jacek Biernat et al. profile →

Peers

Countries citing papers authored by Jacek Biernat

Since Specialization

Citations

This map shows the geographic impact of Jacek Biernat's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jacek Biernat with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jacek Biernat more than expected).

Fields of papers citing papers by Jacek Biernat

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jacek Biernat. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jacek Biernat. The network helps show where Jacek Biernat may publish in the future.

Co-authorship network of co-authors of Jacek Biernat

This figure shows the co-authorship network connecting the top 25 collaborators of Jacek Biernat. A scholar is included among the top collaborators of Jacek Biernat based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jacek Biernat. Jacek Biernat is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Lipid Membrane Templated Misfolding and Self-Assembly of Intrinsically Disordered Tau Protein 2018 ·Biophysical Journal ·(unknown), (unknown), Jacek Biernat, Eckhard Mandelkow�, Eva Y.	2
2	Time course of Tau toxicity and pharmacologic prevention in a cell model of Tauopathy 2017 ·Neurobiology of Aging ·Marcus Pickhardt, Jacek Biernat, (unknown), Frank J.A. Dennissen, Thomas Timm, (unknown), Eva‐Maria Mandelkow, Eckhard Mandelkow�	16
3	Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau breakdown → 2017 ·Nature Communications ·Susmitha Ambadipudi, Jacek Biernat, Dietmar Riedel, Eckhard Mandelkow�, Markus Zweckstetter	569
4	Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action 2014 ·Cell ·G Elif Karagöz, Afonso M.S. Duarte, Elias Akoury, Hans Ippel, Jacek Biernat, Tania Morán Luengo, Martina Radli, Tatiana Didenko, Bryce A. Nordhues, Dmitry B. Veprintsev, Chad A. Dickey, Eckhard Mandelkow�, Markus Zweckstetter, Rolf Boelens, Tobias Madl, Stefan Rüdiger	241
5	Oligomer Formation of Tau Protein Hyperphosphorylated in Cells 2014 ·Journal of Biological Chemistry ·Katharina Tepper, Jacek Biernat, Satish Kumar, Susanne Wegmann, Thomas Timm, (unknown), Lars Redecke, Eva‐Maria Mandelkow, Daniel J. Müller, Eckhard Mandelkow�	123
6	Stages and Conformations of the Tau Repeat Domain during Aggregation and Its Effect on Neuronal Toxicity 2014 ·Journal of Biological Chemistry ·Satish Kumar, Katharina Tepper, Senthilvelrajan Kaniyappan, Jacek Biernat, Susanne Wegmann, Eva‐Maria Mandelkow, Daniel J. Müller, Eckhard Mandelkow�	67
7	Predictive Atomic Resolution Descriptions of Intrinsically Disordered hTau40 and α-Synuclein in Solution from NMR and Small Angle Scattering 2013 ·Structure ·M. Schwalbe, Valéry Ozenne, Stefan Bibow, Mariusz Jaremko, Łukasz Jaremko, Michał J. Gajda, Malene Ringkjøbing Jensen, Jacek Biernat, Stefan Becker, Eckhard Mandelkow�, Markus Zweckstetter, Martin Blackledge	156
8	Low‐Power Solid‐State NMR Experiments for Resonance Assignment under Fast Magic‐Angle Spinning 2009 ·ChemPhysChem ·Vinesh Vijayan, Jean‐Philippe Demers, Jacek Biernat, Eckhard Mandelkow�, Stefan Becker, Adam Lange	40
9	Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation 2008 ·Journal of Biological Chemistry ·Sadasivam Jeganathan�, Antje Hascher, Subashchandrabose Chinnathambi, Jacek Biernat, Eva‐Maria Mandelkow, Eckhard Mandelkow�	205
10	Inhibition of APP Trafficking by Tau Protein Does Not Increase the Generation of Amyloid‐β Peptides 2006 ·Traffic ·Claire Goldsbury, Maria‐Magdalena Mocanu, Edda Thies, Christoph Kaether, Christian Haass, Patrick Keller, Jacek Biernat, Eckhard Mandelkow�, Eva‐Maria Mandelkow, (unknown), (unknown)	68
11	Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy 2005 ·Journal of Biological Chemistry ·Inna Khlistunova, Jacek Biernat, Yipeng Wang, Marcus Pickhardt, Martin von Bergen�, Zuzana Gažová, Eckhard Mandelkow�, Eva‐Maria Mandelkow	287
12	MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons 2004 ·The Journal of Cell Biology ·Eva‐Maria Mandelkow, Edda Thies, Bernhard Trinczek, Jacek Biernat, (unknown)	186
13	Tau aggregation is driven by a transition from random coil to beta sheet structure 2004 ·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Martin von Bergen�, Stefan Barghorn, Jacek Biernat, Eva‐Maria Mandelkow, Eckhard Mandelkow�	297
14	Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease breakdown → 2001 ·Journal of Biological Chemistry ·Sophie Leclerc, Matthieu Garnier, (unknown), Doris Marko, James Bibb, Gretchen L. Snyder, Paul Greengard, Jacek Biernat, (unknown), Eva‐Maria Mandelkow, Gerhard Eisenbrand, Laurent Meijer	635
15	The Development of Cell Processes Induced by tau Protein Requires Phosphorylation of Serine 262 and 356 in the Repeat Domain and Is Inhibited by Phosphorylation in the Proline-rich Domains 1999 ·Molecular Biology of the Cell ·Jacek Biernat, Eva‐Maria Mandelkow	115
16	Phosphorylation of tau protein by recombinant GSK‐3β: pronounced phosphorylation at select Ser/Thr‐Pro motifs but no phosphorylation at Ser262 in the repeat domain 1999 ·FEBS Letters ·Robert Godemann, Jacek Biernat, Eva‐Maria Mandelkow, Eckhard Mandelkow�	96
17	Phosphorylation of Microtubule-associated Proteins MAP2 and MAP4 by the Protein Kinase p110mark 1996 ·Journal of Biological Chemistry ·Susanne Illenberger, Gerard Drewes, Bernhard Trinczek, Jacek Biernat, Helmut E. Meyer, J.B. Olmsted, Eva‐Maria Mandelkow, Eckhard Mandelkow�	158
18	RNA stimulates aggregation of microtubule‐associated protein tau into Alzheimer‐like paired helical filaments 1996 ·FEBS Letters ·(unknown), Peter Friedhoff, Jacek Biernat, Eckhard Mandelkow�, Eva‐Maria Mandelkow, (unknown), (unknown)	427
19	Tau domains, phosphorylation, and interactions with microtubules 1995 ·Neurobiology of Aging ·Eva‐Maria Mandelkow, Jacek Biernat, Gerard Drewes, N. Gustke, Bernhard Trinczek	248
20	Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding breakdown → 1993 ·Neuron ·Jacek Biernat, N. Gustke, Gerard Drewes, Eva‐Maria Mandelkow, Eckhard Mandelkow�	633

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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