Eric R. Fearon

59.7k total citations · 18 hit papers
191 papers, 45.9k citations indexed

About

Eric R. Fearon is a scholar working on Molecular Biology, Oncology and Pathology and Forensic Medicine. According to data from OpenAlex, Eric R. Fearon has authored 191 papers receiving a total of 45.9k indexed citations (citations by other indexed papers that have themselves been cited), including 118 papers in Molecular Biology, 61 papers in Oncology and 60 papers in Pathology and Forensic Medicine. Recurrent topics in Eric R. Fearon's work include Genetic factors in colorectal cancer (55 papers), Wnt/β-catenin signaling in development and cancer (46 papers) and Cancer-related gene regulation (38 papers). Eric R. Fearon is often cited by papers focused on Genetic factors in colorectal cancer (55 papers), Wnt/β-catenin signaling in development and cancer (46 papers) and Cancer-related gene regulation (38 papers). Eric R. Fearon collaborates with scholars based in United States, Japan and Poland. Eric R. Fearon's co-authors include Bert Vogelstein, Stanley R. Hamilton, Scott E. Kern, Kathleen R. Cho, Johannes L. Bos, Alida M.M. Smits, Mark Leppert, Suzanne J. Baker, Karen M. Hajra and Janice Nigro and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Eric R. Fearon

190 papers receiving 44.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A genetic model for colorectal tumorigenesis

1990 9.1k citations Eric R. Fearon et al. profile →
Genetic Alterations during Colorectal-Tumor Development

1988 5.2k citations Eric R. Fearon et al. profile →
Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 1.7k citations Eric R. Fearon et al. profile →
Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53

1990 1.6k citations Eric R. Fearon et al. profile →
Prevalence of ras gene mutations in human colorectal cancers

1987 1.5k citations Eric R. Fearon et al. profile →
Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 1.4k citations Eric R. Fearon, Kathleen R. Cho et al. profile →
Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts

1997 1.3k citations Eric R. Fearon et al. profile →
Molecular Genetics of Colorectal Cancer

2011 1.3k citations Eric R. Fearon profile →
Allelotype of Colorectal Carcinomas

1989 1.1k citations Eric R. Fearon et al. profile →
p53-Mediated Activation of miRNA34 Candidate Tumor-Suppressor Genes

2007 918 citations Guido T. Bommer, Ying Feng et al. profile →
Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution

2009 871 citations Eric R. Fearon et al. profile →
The SLUG zinc-finger protein represses E-cadherin in breast cancer.

2002 856 citations Eric R. Fearon et al. PubMed profile →
Scrambled exons

1991 774 citations Kathleen R. Cho, Eric R. Fearon et al. profile →
Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

1990 769 citations Eric R. Fearon et al. profile →
MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells

2009 558 citations Guido T. Bommer, Eric R. Fearon et al. PLoS ONE profile →
A Wnt–Axin2–GSK3β cascade regulates Snail1 activity in breast cancer cells

2006 525 citations Ichiro Ota, Eric R. Fearon et al. profile →
Clonal Analysis of Human Colorectal Tumors

1987 506 citations Eric R. Fearon et al. profile →
Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

2021 188 citations Hannah N. Bell, Ryan J. Rebernick et al. Cancer Cell profile →

Peers

Countries citing papers authored by Eric R. Fearon

Since Specialization

Citations

This map shows the geographic impact of Eric R. Fearon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric R. Fearon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric R. Fearon more than expected).

Fields of papers citing papers by Eric R. Fearon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric R. Fearon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric R. Fearon. The network helps show where Eric R. Fearon may publish in the future.

Co-authorship network of co-authors of Eric R. Fearon

This figure shows the co-authorship network connecting the top 25 collaborators of Eric R. Fearon. A scholar is included among the top collaborators of Eric R. Fearon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eric R. Fearon. Eric R. Fearon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	CCN6 Suppresses Metaplastic Breast Carcinoma by Antagonizing Wnt/β-Catenin Signaling to Inhibit EZH2-Driven EMT 2024 ·Cancer Research ·(unknown), (unknown), (unknown), (unknown), Sabra Djomehri, Giuseppina Augimeri, Nicholas J. Carruthers, Raymond G. Cavalcante, Francesca Giordano, Sebastiano Andò, Alexey I. Nesvizhskii, Eric R. Fearon, Celina G. Kleer	1
2	Altering the Microbiome Inhibits Tumorigenesis in a Mouse Model of Oviductal High-Grade Serous Carcinoma 2021 ·Cancer Research ·Lixing Chen, Yali Zhai, Yisheng Wang, Eric R. Fearon, Gabriel Núñez, Naohiro Inohara, Kathleen R. Cho	27
3	Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance breakdown → 2021 ·Cancer Cell ·Hannah N. Bell, Ryan J. Rebernick, Joshua Goyert, Rashi Singhal, Miljan Kuljanin, Samuel A. Kerk, Wesley Huang, Nupur K. Das, Anthony Andren, Sumeet Solanki, Shannon L. Miller, Peter K. Todd, Eric R. Fearon, Costas A. Lyssiotis, Steven P. Gygi, Joseph D. Mancias, Yatrik M. Shah	188
4	Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts 2019 ·Cancer Research ·Kevin W. McCool, Zachary T. Freeman, Yali Zhai, Rong Wu, Kevin Hu, Chia‐Jen Liu, Scott A. Tomlins, Eric R. Fearon, Brian Magnuson, Rork Kuick, Kathleen R. Cho	17
5	Lymph Node Metastases in Colon Cancer Are Polyclonal 2017 ·Clinical Cancer Research ·Peter Ulintz, Joel K. Greenson, Rong Wu, Eric R. Fearon, Karin M. Hardiman	62
6	Activation of Wnt/β-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell States 2016 ·Cancer Research ·Elisabeth A. Pedersen, Rajasree Menon, Kelly M. Bailey, Dafydd G. Thomas, (unknown), (unknown), Hongwei Wang, Ping Qü, Antje Hoering, Eric R. Fearon, Rashmi Chugh, Elizabeth R. Lawlor	65
7	Preclinical Testing of PI3K/AKT/mTOR Signaling Inhibitors in a Mouse Model of Ovarian Endometrioid Adenocarcinoma 2011 ·Clinical Cancer Research ·Rong Wu, Tom C. Hu, Alnawaz Rehemtulla, Eric R. Fearon, Kathleen R. Cho	60
8	In Vivo Fluorescence-Based Endoscopic Detection of Colon Dysplasia in the Mouse Using a Novel Peptide Probe 2011 ·PLoS ONE ·Sharon Miller, Bishnu Joshi, Ying Feng, (unknown), Eric R. Fearon, Thomas D. Wang	64
9	Mutant Kras Promotes Hyperplasia and Alters Differentiation in the Colon Epithelium but Does Not Expand the Presumptive Stem Cell Pool 2011 ·Gastroenterology ·Ying Feng, Guido T. Bommer, Jenny Zhao, Maranne Green, (unknown), Yali Zhai, Kelly L. Brown, Aaron Burberry, Kathleen R. Cho, Eric R. Fearon	99
10	CDX2 Regulates Multidrug Resistance 1 Gene Expression in Malignant Intestinal Epithelium 2010 ·Cancer Research ·Yuji Takakura, Takao Hinoi, Naohide Oue, (unknown), Yasuo Kawaguchi, Masazumi Okajima, Aytekin Akyol, Eric R. Fearon, Wataru Yasui, Hideki Ohdan	34
11	COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion 2010 ·Journal of Clinical Investigation ·Bart van de Sluis, Xicheng Mao, Yali Zhai, Arjan J. Groot, Jeroen F. Vermeulen, Elsken van der Wall, P. J. van Diest, Marten H. Hofker, Cisca Wijmenga, Leo W. J. Klomp, Kathleen R. Cho, Eric R. Fearon, Marc Vooijs, Ezra Burstein	103
12	Gene Expression Patterns in Mismatch Repair-Deficient Colorectal Cancers Highlight the Potential Therapeutic Role of Inhibitors of the Phosphatidylinositol 3-Kinase-AKT-Mammalian Target of Rapamycin Pathway 2009 ·Clinical Cancer Research ·Eduardo Vilar, Bhramar Mukherjee, Rork Kuick, Leon Raskin, David E. Misek, Jeremy M. G. Taylor, Thomas J. Giordano, Samir Hanash, Eric R. Fearon, Gad Rennert, Stephen B. Gruber	46
13	Gene Expression Analysis of Preinvasive and Invasive Cervical Squamous Cell Carcinomas Identifies HOXC10 as a Key Mediator of Invasion 2007 ·Cancer Research ·Yali Zhai, Rork Kuick, Bin Nan, Ichiro Ota, Stephen J. Weiss, Cornelia L. Trimble, Eric R. Fearon, Kathleen R. Cho	203
14	DRO1, a Gene Down-regulated by Oncogenes, Mediates Growth Inhibition in Colon and Pancreatic Cancer Cells 2004 ·Journal of Biological Chemistry ·Guido T. Bommer, (unknown), (unknown), (unknown), Sören T. Eichhorst, Thomas Brabletz, Gang Hu, Thomas Fröhlich, Georg J. Arnold, (unknown), Burkhard Göke, Eric R. Fearon, Frank T. Kolligs	49
15	Amplification and Overexpression of the L-MYC Proto-Oncogene in Ovarian Carcinomas 2003 ·American Journal Of Pathology ·Rong Wu, Lin Lin, David G. Beer, Lora H. Ellenson, Barbara Lamb, Jean-Marie Rouillard, Rork Kuick, Samir Hanash, Donald R. Schwartz, Eric R. Fearon, Kathleen R. Cho	48
16	Role of β-Catenin/T-Cell Factor-Regulated Genes in Ovarian Endometrioid Adenocarcinomas 2002 ·American Journal Of Pathology ·Yali Zhai, Rong Wu, Donald R. Schwartz, (unknown), Heather Reed, Frank T. Kolligs, Marvin T. Nieman, Eric R. Fearon, Kathleen R. Cho	88
17	Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas. 2002 ·PubMed ·Donald R. Schwartz, Sharon L. R. Kardia, Kerby Shedden, Rork Kuick, George Michailidis, Jeremy M. G. Taylor, David E. Misek, Rong Wu, Yali Zhai, (unknown), Heather Reed, Lora H. Ellenson, Thomas J. Giordano, Eric R. Fearon, Samir Hanash, Kathleen R. Cho	348
18	Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system 2002 ·Gut ·David Qualtrough, Takao Hinoi, Eric R. Fearon, Christos Paraskeva	51
19	Frequent alterations in E-cadherin and alpha- and beta-catenin expression in human breast cancer cell lines. 1995 ·PubMed ·William E. Pierceall, Amy S. Woodard, Jon S. Morrow, David L. Rimm, Eric R. Fearon	119
20	Intracellular Leucine Zipper Interactions Suggest c-Myc Hetero-Oligomerization 1991 ·Molecular and Cellular Biology ·Chi V. Dang, J. Barrett, Manuel Villa‐Garcia, Linda Resar, Gregory J. Kato, Eric R. Fearon	52

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