Christos Paraskeva

10.3k citations

112 papers · 8.5k indexed · 2 hit papers · h-index 46

Molecular Biology top 1%
Oncology top 0.5%
Cancer Research top 0.5%
Pathology and Forensic Medicine top 0.5%
Genetics top 1%

Co-authors: Ann C. Williams Abderrahmane Kaidi Angela Hague Alexander Greenhough Douglas J.E. Elder Bert Vogelstein Sanford D. Markowitz James K. V. Willson
Topics: Genetic factors in colorectal cancer (23 papers)Glycosylation and Glycoproteins Research (17 papers)Inflammatory mediators and NSAID effects (17 papers)
Cited by: Cancer Research Oncology Pathology and Forensic Medicine
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Nature Medicine
Partner nations: United Kingdom United States Germany

In The Last Decade

Christos Paraskeva

110 papers receiving 8.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

2009 998 citations Alexander Greenhough, Ann C. Williams et al. profile →
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.

1990 906 citations Christos Paraskeva et al. profile →

Peers

Countries citing papers authored by Christos Paraskeva

Since Specialization

Citations

This map shows the geographic impact of Christos Paraskeva's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christos Paraskeva with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christos Paraskeva more than expected).

Fields of papers citing papers by Christos Paraskeva

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christos Paraskeva. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christos Paraskeva. The network helps show where Christos Paraskeva may publish in the future.

Co-authorship network of co-authors of Christos Paraskeva

This figure shows the co-authorship network connecting the top 25 collaborators of Christos Paraskeva. A scholar is included among the top collaborators of Christos Paraskeva based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christos Paraskeva. Christos Paraskeva is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells 2019 ·Disease Models & Mechanisms ·(unknown),(unknown),T J Collard,Alexander Greenhough,A Chambers,Richard Clarkson,Christos Paraskeva,Ann C. Williams	24
2	BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling 2015 ·Gut ·(unknown),T J Collard,(unknown),(unknown),Alexander Greenhough,Maryam Hamdollah‐Zadeh,Anil K. Ghosh,Richard Poulsom,Christos Paraskeva,Andrew Silver,Ann C. Williams	37
3	miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance 2013 ·Cancer Research ·Lei Zhang,Karen Pickard,Veronika Jenei,Marc D. Bullock,Amanda S. Bruce,Richard Mitter,Gavin Kelly,Christos Paraskeva,(unknown),John Primrose,Gareth J. Thomas,Graham Packham,Alex H. Mirnezami	119
4	BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor β (TGF-β1) in colorectal tumour cells 2012 ·Oncogene ·(unknown),T J Collard,(unknown),Alexander Greenhough,Angela Hague,Paul A. Townsend,Christos Paraskeva,Ann C. Williams	17
5	Inhibition of COX‐2 with NS‐398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: possibilities for combination therapy 2007 ·Cell Proliferation ·(unknown),Andrea Buda,Simon Chell,Douglas J.E. Elder,M Moorghen,Christos Paraskeva,David Qualtrough,Massimo Pignatelli	32
6	Increased EP4 Receptor Expression in Colorectal Cancer Progression Promotes Cell Growth and Anchorage Independence 2006 ·Cancer Research ·Simon Chell,Ian R. Witherden,(unknown),(unknown),Andrew Herman,David Qualtrough,Ann C. Williams,Christos Paraskeva	126
7	Hedgehog signalling in colorectal tumour cells: Induction of apoptosis with cyclopamine treatment 2004 ·International Journal of Cancer ·David Qualtrough,Andrea Buda,William Gaffield,Ann C. Williams,Christos Paraskeva	138
8	Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system 2002 ·Gut ·David Qualtrough,Takao Hinoi,Eric R. Fearon,Christos Paraskeva	51
9	Human colorectal adenomas demonstrate a size‐dependent increase in epithelial cyclooxygenase‐2 expression 2002 ·The Journal of Pathology ·Douglas J.E. Elder,(unknown),(unknown),M Moorghen,Christos Paraskeva	69
10	The MEK/ERK pathway mediates COX‐2‐selective NSAID‐induced apoptosis and induced COX‐2 protein expression in colorectal carcinoma cells 2002 ·International Journal of Cancer ·Douglas J.E. Elder,(unknown),(unknown),Christos Paraskeva	83
11	The Protrusive Phase and Full Development of Integrin-Dependent Adhesions in Colon Epithelial Cells Require FAK- and ERKMediated Actin Spike Formation: Deregulation in Cancer Cells 2001 ·Neoplasia ·Valerie G. Brunton,Valerie J. Fincham,Gordon W. McLean,Steven J. Winder,Christos Paraskeva,John F. Marshall,Margaret C. Frame	22
12	The Catalytic Activity of the Src Family Kinases Is Required to Disrupt Cadherin-dependent Cell–Cell Contacts 2000 ·Molecular Biology of the Cell ·(unknown),Gordon W. McLean,Anne W. Wyke,Christos Paraskeva,E. Kenneth Parkinson,Margaret C. Frame,Valerie G. Brunton	140
13	Coordinated modulation of the fibroblast growth factor dual receptor mechanism during transformation from human colon adenoma to carcinoma 1999 ·International Journal of Cancer ·Gordon C. Jayson,Corinne Vivès,Christos Paraskeva,K. P. Schofield,(unknown),(unknown),John T. Gallagher	42
14	Heparan Sulfate Undergoes Specific Structural Changes during the Progression from Human Colon Adenoma to Carcinoma in Vitro 1998 ·Journal of Biological Chemistry ·Gordon C. Jayson,Malcolm Lyon,Christos Paraskeva,Jeremy E. Turnbull,(unknown),John T. Gallagher	113
15	Butyrate- but not TGFβ1-induced apoptosis of colorectal adenoma cells is associated with increased expression of the differentiation markers E-cadherin and alkaline phosphatase 1997 ·Cell Death and Differentiation ·Alison J. Butt,Angela Hague,Christos Paraskeva	23
16	The short-chain fatty acid butyrate induces apoptosis in colorectal tumour cell lines 1995 ·European Journal of Cancer Prevention ·Angela Hague,Christos Paraskeva	89
17	Loss of apc protein expressed by human colonic epithelial cells and the appearance of a specific low‐molecular‐weight form is associated with apoptosis IN vitro 1994 ·International Journal of Cancer ·(unknown),Ann C. Williams,Angela Hague,Alison J. Butt,Christos Paraskeva	51
18	Correlation of cellular differentiation in human colorectal carcinoma and adenoma cell lines with metabolite profiles determined by ¹H magnetic resonance spectroscopy 1994 ·International Journal of Cancer ·Wanda B. Mackinnon,Lily I. Huschtscha,(unknown),Rebecca Hancock,Christos Paraskeva,Carolyn E. Mountford	42
19	Escape from negative regulation of growth by transforming growth factor β and from the induction of apoptosis by the dietary agent sodium butyrate may be important in colorectal carcinogenesis 1993 ·Cancer and Metastasis Reviews ·Angela Hague,Alex Manning,(unknown),Christos Paraskeva	19
20	Promotability and tissue specificity of hereditary cancer genes: Do hereditary cancer patients have a reduced requirement for tumor promotion because all their somatic cells are heterozygous at the predisposing locus? 1992 ·Molecular Carcinogenesis ·Christos Paraskeva,Ann C. Williams	2

About Christos Paraskeva

Christos Paraskeva is a scholar working on Cancer Research, Oncology and Pathology and Forensic Medicine, having authored 112 papers that have together received 8.5k indexed citations. Recurring topics across this work include Genetic factors in colorectal cancer (23 papers), Glycosylation and Glycoproteins Research (17 papers) and Inflammatory mediators and NSAID effects (17 papers). The work is most often cited by research in Cancer Research (2.3k citations), Oncology (2.8k citations) and Pathology and Forensic Medicine (1.6k citations). Christos Paraskeva has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Ann C. Williams, Abderrahmane Kaidi, Angela Hague, Alexander Greenhough, Douglas J.E. Elder, Bert Vogelstein, Sanford D. Markowitz, James K. V. Willson, Stanley R. Hamilton and David Qualtrough. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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