Christos Paraskeva

10.3k citations

112 papers · 8.5k indexed · 2 hit papers · h-index 46

Cancer Research top 0.5%
- Cancer Genomics and Diagnostics 10
Oncology top 0.5%
- Cancer-related Molecular Pathways 15
- Colorectal Cancer Treatments and Studies 14
Pathology and Forensic Medicine top 0.5%
- Genetic factors in colorectal cancer 23
Pharmacology top 0.5%
- Inflammatory mediators and NSAID effects 17
Molecular Biology top 1%
- Glycosylation and Glycoproteins Research 17
Genetics
- Estrogen and related hormone effects 12
Organic Chemistry
- Carbohydrate Chemistry and Synthesis 10

Co-authors: Ann C. Williams Abderrahmane Kaidi Angela Hague Alexander Greenhough Douglas J.E. Elder Bert Vogelstein Sanford D. Markowitz James K. V. Willson
Cited by: Cancer Research Oncology Pathology and Forensic Medicine
Journals: Proceedings of the National Academy of Sciences (1 paper)Journal of Biological Chemistry (1 paper)Nature Medicine (1 paper)
Partner nations: United Kingdom United States Germany

In The Last Decade

Christos Paraskeva

110 papers receiving 8.3k citations

Hit Papers

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Peers

Countries citing papers authored by Christos Paraskeva

Since Specialization

Citations

This map shows the geographic impact of Christos Paraskeva's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christos Paraskeva with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christos Paraskeva more than expected).

Fields of papers citing papers by Christos Paraskeva

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christos Paraskeva. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christos Paraskeva. The network helps show where Christos Paraskeva may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Christos Paraskeva, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christos Paraskeva Line = papers co-authored together Christos Paraskeva links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells Disease Models & Mechanisms ·Danny Legge,Alex P. Shephard,T J Collard,Alexander Greenhough,A Chambers,Richard Clarkson,Christos Paraskeva,Ann C. Williams	2019	24
2	BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling Gut ·Bettina C. Urban,T J Collard,Catherine Eagle,S L Southern,Alexander Greenhough,Maryam Hamdollah‐Zadeh,Anil K. Ghosh,Richard Poulsom,Christos Paraskeva,Andrew Silver,Ann C. Williams	2015	37
3	miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Cancer Research ·Lei Zhang,Karen Pickard,Veronika Jenei,Marc D. Bullock,Amanda S. Bruce,Richard Mitter,Gavin Kelly,Christos Paraskeva,John Strefford,John Primrose,Gareth J. Thomas,Graham Packham,Alex H. Mirnezami	2013	119
4	BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor β (TGF-β1) in colorectal tumour cells Oncogene ·V R Skeen,T J Collard,S L Southern,Alexander Greenhough,Angela Hague,Paul A. Townsend,Christos Paraskeva,Ann C. Williams	2012	17
5	Inhibition of COX‐2 with NS‐398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: possibilities for combination therapy Cell Proliferation ·N Masoodhu Banu,Andrea Buda,Simon Chell,Douglas J.E. Elder,M Moorghen,Christos Paraskeva,David Qualtrough,Massimo Pignatelli	2007	32
6	Increased EP4 Receptor Expression in Colorectal Cancer Progression Promotes Cell Growth and Anchorage Independence Cancer Research ·Simon Chell,Ian R. Witherden,Richard R. Dobson,Morganaden Moorghen,Andrew Herman,David Qualtrough,Ann C. Williams,Christos Paraskeva	2006	126
7	Hedgehog signalling in colorectal tumour cells: Induction of apoptosis with cyclopamine treatment International Journal of Cancer ·David Qualtrough,Andrea Buda,William Gaffield,Ann C. Williams,Christos Paraskeva	2004	138
8	Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system Gut ·David Qualtrough,Takao Hinoi,Eric R. Fearon,Christos Paraskeva	2002	51
9	Human colorectal adenomas demonstrate a size‐dependent increase in epithelial cyclooxygenase‐2 expression The Journal of Pathology ·Douglas J.E. Elder,Jenny A. Baker,Nahida A. Banu,M Moorghen,Christos Paraskeva	2002	69
10	The MEK/ERK pathway mediates COX‐2‐selective NSAID‐induced apoptosis and induced COX‐2 protein expression in colorectal carcinoma cells International Journal of Cancer ·Douglas J.E. Elder,Dawn E. Halton,Laura C. Playle,Christos Paraskeva	2002	83
11	The Protrusive Phase and Full Development of Integrin-Dependent Adhesions in Colon Epithelial Cells Require FAK- and ERKMediated Actin Spike Formation: Deregulation in Cancer Cells Neoplasia ·Valerie G. Brunton,Valerie J. Fincham,Gordon W. McLean,Steven J. Winder,Christos Paraskeva,John F. Marshall,Margaret C. Frame	2001	22
12	The Catalytic Activity of the Src Family Kinases Is Required to Disrupt Cadherin-dependent Cell–Cell Contacts Molecular Biology of the Cell ·Dewi W. Owens,Gordon W. McLean,Anne W. Wyke,Christos Paraskeva,E. Kenneth Parkinson,Margaret C. Frame,Valerie G. Brunton	2000	140
13	Coordinated modulation of the fibroblast growth factor dual receptor mechanism during transformation from human colon adenoma to carcinoma International Journal of Cancer ·Gordon C. Jayson,Corinne Vivès,Christos Paraskeva,K. P. Schofield,Jacquie Coutts,Alison Fleetwood,John T. Gallagher	1999	42
14	Heparan Sulfate Undergoes Specific Structural Changes during the Progression from Human Colon Adenoma to Carcinoma in Vitro Journal of Biological Chemistry ·Gordon C. Jayson,Malcolm Lyon,Christos Paraskeva,Jeremy E. Turnbull,Jonathan A. Deakin,John T. Gallagher	1998	113
15	Butyrate- but not TGFβ1-induced apoptosis of colorectal adenoma cells is associated with increased expression of the differentiation markers E-cadherin and alkaline phosphatase Cell Death and Differentiation ·Alison J. Butt,Angela Hague,Christos Paraskeva	1997	23
16	The short-chain fatty acid butyrate induces apoptosis in colorectal tumour cell lines European Journal of Cancer Prevention ·Angela Hague,Christos Paraskeva	1995	89
17	Loss of apc protein expressed by human colonic epithelial cells and the appearance of a specific low‐molecular‐weight form is associated with apoptosis IN vitro International Journal of Cancer ·S. Browne,Ann C. Williams,Angela Hague,Alison J. Butt,Christos Paraskeva	1994	51
18	Correlation of cellular differentiation in human colorectal carcinoma and adenoma cell lines with metabolite profiles determined by ¹H magnetic resonance spectroscopy International Journal of Cancer ·Wanda B. Mackinnon,Lily I. Huschtscha,Kathy Dent,Rebecca Hancock,Christos Paraskeva,Carolyn E. Mountford	1994	42
19	Escape from negative regulation of growth by transforming growth factor β and from the induction of apoptosis by the dietary agent sodium butyrate may be important in colorectal carcinogenesis Cancer and Metastasis Reviews ·Angela Hague,Alex Manning,Jos W.J. van der Stappen,Christos Paraskeva	1993	19
20	Promotability and tissue specificity of hereditary cancer genes: Do hereditary cancer patients have a reduced requirement for tumor promotion because all their somatic cells are heterozygous at the predisposing locus? Molecular Carcinogenesis ·Christos Paraskeva,Ann C. Williams	1992	2

About Christos Paraskeva

Christos Paraskeva is a scholar working on Cancer Research, Oncology and Pathology and Forensic Medicine, having authored 112 papers that have together received 8.5k indexed citations. Recurring topics across this work include Genetic factors in colorectal cancer (23 papers), Glycosylation and Glycoproteins Research (17 papers), Inflammatory mediators and NSAID effects (17 papers), Cancer-related Molecular Pathways (15 papers), Colorectal Cancer Treatments and Studies (14 papers), Estrogen and related hormone effects (12 papers), Cancer Genomics and Diagnostics (10 papers) and Carbohydrate Chemistry and Synthesis (10 papers). The work is most often cited by research in Cancer Research (2.3k citations), Oncology (2.8k citations) and Pathology and Forensic Medicine (1.6k citations). Christos Paraskeva has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Ann C. Williams, Abderrahmane Kaidi, Angela Hague, Alexander Greenhough, Douglas J.E. Elder, Bert Vogelstein, Sanford D. Markowitz, James K. V. Willson, Stanley R. Hamilton and David Qualtrough. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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