Thomas Brabletz

32.9k total citations · 15 hit papers
174 papers, 23.0k citations indexed

About

Thomas Brabletz is a scholar working on Molecular Biology, Oncology and Pathology and Forensic Medicine. According to data from OpenAlex, Thomas Brabletz has authored 174 papers receiving a total of 23.0k indexed citations (citations by other indexed papers that have themselves been cited), including 117 papers in Molecular Biology, 78 papers in Oncology and 35 papers in Pathology and Forensic Medicine. Recurrent topics in Thomas Brabletz's work include Wnt/β-catenin signaling in development and cancer (54 papers), Cancer Cells and Metastasis (53 papers) and Cancer-related gene regulation (37 papers). Thomas Brabletz is often cited by papers focused on Wnt/β-catenin signaling in development and cancer (54 papers), Cancer Cells and Metastasis (53 papers) and Cancer-related gene regulation (37 papers). Thomas Brabletz collaborates with scholars based in Germany, United States and Israel. Thomas Brabletz's co-authors include Simone Brabletz, Thomas Kirchner, Andreas Jung, Otto Schmalhofer, Falk Hlubek, Simone Spaderna, Marc P. Stemmler, Robert A. Weinberg, M. Ángela Nieto and Raghu Kalluri and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Thomas Brabletz

170 papers receiving 22.7k citations

Hit Papers

EMT in cancer 1999 2026 2008 2017 2018 2008 2009 2005 2001 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. EMT in cancer
    2018 1.5k citations Thomas Brabletz et al. profile →
  2. A reciprocal repression between ZEB1 and members of the miR‐200 family promotes EMT and invasion in cancer cells
    2008 1.4k citations Otto Schmalhofer, Simone Spaderna et al. profile →
  3. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
    2009 1.4k citations Otto Schmalhofer, Marc P. Stemmler et al. profile →
  4. Migrating cancer stem cells — an integrated concept of malignant tumour progression
    2005 1.1k citations Thomas Brabletz, Andreas Jung et al. profile →
  5. Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
    2001 868 citations Thomas Brabletz, Andreas Jung et al. profile →
  6. Oncogenic roles of EMT-inducing transcription factors
    2014 823 citations Thomas Brabletz et al. profile →
  7. The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
    2017 729 citations Otto Schmalhofer, Simone Brabletz et al. profile →
  8. The ZEB/miR‐200 feedback loop—a motor of cellular plasticity in development and cancer?
    2010 654 citations Simone Brabletz, Thomas Brabletz profile →
  9. E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
    2009 653 citations Otto Schmalhofer, Simone Brabletz et al. profile →
  10. Wnt/β-catenin signaling in cancer stemness and malignant behavior
    2007 652 citations Thomas Brabletz et al. profile →
  11. β-Catenin Regulates the Expression of the Matrix Metalloproteinase-7 in Human Colorectal Cancer
    1999 555 citations Thomas Brabletz, Andreas Jung et al. American Journal Of Pathology profile →
  12. Wnt signalling induces maturation of Paneth cells in intestinal crypts
    2005 518 citations Thomas Brabletz et al. profile →
  13. To differentiate or not — routes towards metastasis
    2012 494 citations Thomas Brabletz profile →
  14. Dynamic EMT: a multi‐tool for tumor progression
    2021 452 citations Simone Brabletz, Harald Schuhwerk et al. The EMBO Journal profile →
  15. Non-redundant functions of EMT transcription factors
    2018 371 citations Marc P. Stemmler, Rebecca L. Eccles et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Thomas Brabletz 15.3k 10.2k 7.5k 2.4k 2.1k 174 23.0k
Amparo Cano 15.7k 1.0× 9.4k 0.9× 4.8k 0.6× 2.4k 1.0× 1.5k 0.7× 134 22.1k
Yibin Kang 15.7k 1.0× 11.2k 1.1× 8.3k 1.1× 1.8k 0.7× 1.8k 0.8× 193 25.3k
Owen J. Sansom 14.4k 0.9× 8.8k 0.9× 4.9k 0.7× 3.5k 1.5× 1.9k 0.9× 311 23.8k
Andres J. Klein–Szanto 12.0k 0.8× 7.0k 0.7× 4.9k 0.7× 2.6k 1.1× 1.4k 0.7× 383 21.3k
Eduard Batlle 11.7k 0.8× 9.4k 0.9× 3.7k 0.5× 2.3k 1.0× 1.9k 0.9× 87 19.8k
Alfredo Fusco 17.8k 1.2× 7.9k 0.8× 7.2k 1.0× 1.5k 0.6× 2.8k 1.3× 504 29.0k
Ivan Bièche 11.1k 0.7× 5.9k 0.6× 5.7k 0.8× 1.5k 0.6× 1.7k 0.8× 497 20.2k
Ruggero De Maria 13.1k 0.9× 9.1k 0.9× 6.1k 0.8× 2.2k 0.9× 971 0.5× 257 22.8k
Gerhard Christofori 12.4k 0.8× 7.1k 0.7× 4.5k 0.6× 2.9k 1.2× 933 0.4× 163 19.6k

Countries citing papers authored by Thomas Brabletz

Since Specialization
Citations

This map shows the geographic impact of Thomas Brabletz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas Brabletz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas Brabletz more than expected).

Fields of papers citing papers by Thomas Brabletz

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas Brabletz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas Brabletz. The network helps show where Thomas Brabletz may publish in the future.

Co-authorship network of co-authors of Thomas Brabletz

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas Brabletz. A scholar is included among the top collaborators of Thomas Brabletz based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas Brabletz. Thomas Brabletz is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Gregory, Philip A., Thomas Brabletz, Simone Brabletz, et al.. (2025). Strongly regulated transcription factors exert an outsized influence in microRNA-regulated networks. Cell Communication and Signaling. 24(1). 63–63.
2.
Stemmler, Marc P., et al.. (2024). Zeb1 maintains long-term adult hematopoietic stem cell function and extramedullary hematopoiesis. Experimental Hematology. 134. 104177–104177.
3.
Zhou, Xiang, Carlos Agustín Isidro Alonso, Luisina Ongaro, et al.. (2024). ZEB1 Inhibits LHβ Subunit Transcription When Overexpressed, but Is Dispensable for LH Synthesis in Mice. Endocrinology. 165(10). 2 indexed citations
4.
Brabletz, Thomas, Linsey E. Lindley, María T. Abreu, et al.. (2023). Multi-cancer analysis reveals universal association of oncogenic LBH expression with DNA hypomethylation and WNT-Integrin signaling pathways. Cancer Gene Therapy. 30(9). 1234–1248. 8 indexed citations
5.
Han, Yingying, Alvaro Villarreal-Ponce, Guadalupe Gutierrez, et al.. (2022). Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1. Cell Reports. 38(2). 110240–110240. 26 indexed citations
6.
Farkas, Carlos, Aissa Benyoucef, Catherine Carmichael, et al.. (2021). Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity. PLoS Biology. 19(9). e3001394–e3001394. 22 indexed citations
7.
Ferrazzi, Fulvia, Harald Schuhwerk, Sebastian A. Widholz, et al.. (2020). Genome‐wide cooperation of EMT transcription factor ZEB 1 with YAP and AP ‐1 in breast cancer. The EMBO Journal. 39(17). e103209–e103209. 115 indexed citations
8.
Liu, Mingyang, Yu‐Qing Zhang, Jingxuan Yang, et al.. (2019). ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells. Gastroenterology. 158(3). 679–692.e1. 109 indexed citations
9.
Basu, Sayon, Nancy Gavert, Thomas Brabletz, & Avri Ben‐Ze'ev. (2018). The intestinal stem cell regulating gene ASCL2 is required for L1-mediated colon cancer progression. Cancer Letters. 424. 9–18. 20 indexed citations
10.
Bedzhov, Ivan, et al.. (2013). Adhesion, but not a specific cadherin code, is indispensable for ES cell and induced pluripotency. Stem Cell Research. 11(3). 1250–1263. 23 indexed citations
11.
Gavert, Nancy, Amir Ben‐Shmuel, Vance Lemmon, Thomas Brabletz, & Avri Ben‐Ze'ev. (2010). Nuclear factor-κB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells. Journal of Cell Science. 123(12). 2135–2143. 86 indexed citations
12.
Herbst, Andreas, Guido T. Bommer, Lydia Kriegl, et al.. (2009). ITF-2 Is Disrupted via Allelic Loss of Chromosome 18q21, and ITF-2B Expression Is Lost at the Adenoma-Carcinoma Transition. Gastroenterology. 137(2). 639–648.e9. 18 indexed citations
13.
Spaderna, Simone, Otto Schmalhofer, Mandy Wahlbuhl, et al.. (2008). The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer. Cancer Research. 68(2). 537–544. 423 indexed citations
14.
Gavert, Nancy, Michal Sheffer, Shani Raveh, et al.. (2007). Expression of L1-CAM and ADAM10 in Human Colon Cancer Cells Induces Metastasis. Cancer Research. 67(16). 7703–7712. 167 indexed citations
15.
Brabletz, Thomas. (2006). Migrating cancer stem cells: An integrated concept of malignant tumor progression.. Cancer Epidemiology and Prevention Biomarkers. 15. 7 indexed citations
16.
Brabletz, Thomas, Simone Spaderna, J. Kolb, et al.. (2004). Down-Regulation of the Homeodomain Factor Cdx2 in Colorectal Cancer by Collagen Type I. Cancer Research. 64(19). 6973–6977. 113 indexed citations
17.
Hiendlmeyer, Elke, Susanne Regus, Falk Hlubek, et al.. (2004). β-Catenin Up-Regulates the Expression of the Urokinase Plasminogen Activator in Human Colorectal Tumors. Cancer Research. 64(4). 1209–1214. 76 indexed citations
18.
Brueckl, Wolfgang M., Axel Wein, Andreas Jung, et al.. (2002). Ki-67 expression and residual tumour (R) classification are associated with disease-free survival in desmoid tumour patients.. PubMed. 21(5). 3615–20. 14 indexed citations
19.
Brueckl, Wolfgang M., Thomas Brabletz, Klaus Guenther, et al.. (2001). Mismatch repair deficiency in sporadic synchronous colorectal cancer.. PubMed. 20(6C). 4727–32. 12 indexed citations
20.
Brabletz, Thomas, Kathrin Herrmann, Andreas Jung, Gerhard Faller, & Thomas Kirchner. (2000). Expression of Nuclear β-Catenin and c-myc Is Correlated with Tumor Size but Not with Proliferative Activity of Colorectal Adenomas. American Journal Of Pathology. 156(3). 865–870. 138 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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