Thomas Brabletz

32.9k total citations · 15 hit papers
174 papers, 23.0k citations indexed

About

Thomas Brabletz is a scholar working on Molecular Biology, Oncology and Pathology and Forensic Medicine. According to data from OpenAlex, Thomas Brabletz has authored 174 papers receiving a total of 23.0k indexed citations (citations by other indexed papers that have themselves been cited), including 117 papers in Molecular Biology, 78 papers in Oncology and 35 papers in Pathology and Forensic Medicine. Recurrent topics in Thomas Brabletz's work include Wnt/β-catenin signaling in development and cancer (54 papers), Cancer Cells and Metastasis (53 papers) and Cancer-related gene regulation (37 papers). Thomas Brabletz is often cited by papers focused on Wnt/β-catenin signaling in development and cancer (54 papers), Cancer Cells and Metastasis (53 papers) and Cancer-related gene regulation (37 papers). Thomas Brabletz collaborates with scholars based in Germany, United States and Israel. Thomas Brabletz's co-authors include Simone Brabletz, Thomas Kirchner, Andreas Jung, Otto Schmalhofer, Falk Hlubek, Simone Spaderna, Marc P. Stemmler, M. Ángela Nieto, Robert A. Weinberg and Raghu Kalluri and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Thomas Brabletz

170 papers receiving 22.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

EMT in cancer

2018 1.5k citations Thomas Brabletz et al. profile →
A reciprocal repression between ZEB1 and members of the miR‐200 family promotes EMT and invasion in cancer cells

2008 1.4k citations Jörg Schubert, Otto Schmalhofer et al. profile →
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

2009 1.4k citations Jörg Schubert, Otto Schmalhofer et al. Nature Cell Biology profile →
Migrating cancer stem cells — an integrated concept of malignant tumour progression

2005 1.1k citations Thomas Brabletz, Andreas Jung et al. profile →
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

2001 868 citations Thomas Brabletz, Andreas Jung et al. profile →
Oncogenic roles of EMT-inducing transcription factors

2014 823 citations Alain Puisieux, Thomas Brabletz et al. Nature Cell Biology profile →
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

2017 729 citations Otto Schmalhofer, Simone Brabletz et al. Nature Cell Biology profile →
The ZEB/miR‐200 feedback loop—a motor of cellular plasticity in development and cancer?

2010 654 citations Simone Brabletz, Thomas Brabletz profile →
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer

2009 653 citations Otto Schmalhofer, Simone Brabletz et al. profile →
Wnt/β-catenin signaling in cancer stemness and malignant behavior

2007 652 citations Thomas Brabletz et al. profile →
β-Catenin Regulates the Expression of the Matrix Metalloproteinase-7 in Human Colorectal Cancer

1999 555 citations Thomas Brabletz, Andreas Jung et al. profile →
Wnt signalling induces maturation of Paneth cells in intestinal crypts

2005 518 citations Thomas Brabletz et al. Nature Cell Biology profile →
To differentiate or not — routes towards metastasis

2012 494 citations Thomas Brabletz profile →
Dynamic EMT: a multi‐tool for tumor progression

2021 452 citations Simone Brabletz, Harald Schuhwerk et al. The EMBO Journal profile →
Non-redundant functions of EMT transcription factors

2018 371 citations Marc P. Stemmler, Rebecca L. Eccles et al. Nature Cell Biology profile →

Peers

Countries citing papers authored by Thomas Brabletz

Since Specialization

Citations

This map shows the geographic impact of Thomas Brabletz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas Brabletz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas Brabletz more than expected).

Fields of papers citing papers by Thomas Brabletz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas Brabletz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas Brabletz. The network helps show where Thomas Brabletz may publish in the future.

Co-authorship network of co-authors of Thomas Brabletz

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas Brabletz. A scholar is included among the top collaborators of Thomas Brabletz based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas Brabletz. Thomas Brabletz is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Strongly regulated transcription factors exert an outsized influence in microRNA-regulated networks 2025 ·Cell Communication and Signaling ·(unknown), (unknown), Philip A. Gregory, (unknown), Thomas Brabletz, Simone Brabletz, (unknown), Gregory J. Goodall, Katherine A. Pillman, Cameron P. Bracken	0
2	ZEB1 Inhibits LHβ Subunit Transcription When Overexpressed, but Is Dispensable for LH Synthesis in Mice 2024 ·Endocrinology ·(unknown), Xiang Zhou, Carlos Agustín Isidro Alonso, Luisina Ongaro, (unknown), (unknown), Thomas Brabletz, Simone Brabletz, Marc P. Stemmler, Ulrich Boehm, Daniel J. Bernard	2
3	Zeb1 maintains long-term adult hematopoietic stem cell function and extramedullary hematopoiesis 2024 ·Experimental Hematology ·(unknown), (unknown), (unknown), Marc P. Stemmler, Simone Brabletz, Thomas Brabletz, Neil P. Rodrigues	0
4	Multi-cancer analysis reveals universal association of oncogenic LBH expression with DNA hypomethylation and WNT-Integrin signaling pathways 2023 ·Cancer Gene Therapy ·(unknown), Thomas Brabletz, Linsey E. Lindley, María T. Abreu, Nagaraj S. Nagathihalli, Alexander Zaika, Karoline J. Briegel	8
5	Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1 2022 ·Cell Reports ·Yingying Han, Alvaro Villarreal-Ponce, Guadalupe Gutierrez, Quy Nguyen, Peng Sun, Ting Wu, (unknown), Geert Berx, Thomas Brabletz, Kai Kessenbrock, Yi Arial Zeng, Kazuhide Watanabe, Xing Dai	26
6	Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity 2021 ·PLoS Biology ·(unknown), Carlos Farkas, Aissa Benyoucef, Catherine Carmichael, Katharina Haigh, Nicholas C. Wong, Danny Huylebroeck, Marc P. Stemmler, Simone Brabletz, Thomas Brabletz, Christian M. Nefzger, Steven Goossens, Geert Berx, José M. Polo, Jody J. Haigh	22
7	The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus 2021 ·Cell Reports ·Bhavana Gupta, Adam C. Errington, Ana Jimenez‐Pascual, (unknown), Simone Brabletz, Marc P. Stemmler, Thomas Brabletz, David Petřík, Florian A. Siebzehnrübl	19
8	Genome‐wide cooperation of EMT transcription factor ZEB 1 with YAP and AP ‐1 in breast cancer 2020 ·The EMBO Journal ·(unknown), Fulvia Ferrazzi, Harald Schuhwerk, Sebastian A. Widholz, (unknown), (unknown), (unknown), Julia Kleemann, (unknown), Ulrike Bönisch, Soeren Lukassen, Rebecca L. Eccles, Christian Schmidl, Marc P. Stemmler, Thomas Brabletz, Simone Brabletz	115
9	ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells 2019 ·Gastroenterology ·Mingyang Liu, Yu‐Qing Zhang, Jingxuan Yang, Xiaobo Cui, Zhijun Zhou, Hanxiang Zhan, Kai Ding, Xiang Tian, Zhibo Yang, Kar‐Ming Fung, Barish H. Edil, Russell G. Postier, Michael S. Bronze, Martín E. Fernández-Zapico, Marc P. Stemmler, Thomas Brabletz, Yiping Li, Courtney W. Houchen, Min Li	109
10	Oncogenic roles of EMT-inducing transcription factors breakdown → 2014 ·Nature Cell Biology ·Alain Puisieux, Thomas Brabletz, Julie Caramel	823
11	p53 spreads out further: suppression of EMT and stemness by activating miR-200c expression 2011 ·Cell Research ·Jörg Schubert, Thomas Brabletz	45
12	Nuclear factor-κB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells 2010 ·Journal of Cell Science ·Nancy Gavert, Amir Ben‐Shmuel, Vance Lemmon, Thomas Brabletz, Avri Ben‐Ze'ev	86
13	The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer 2008 ·Cancer Research ·Simone Spaderna, Otto Schmalhofer, Mandy Wahlbuhl, Arno Dimmler, Katja Bauer, Aneesa Sultan, Falk Hlubek, Andreas Jung, Dennis Strand, Andreas Eger, Thomas Kirchner, Jürgen Behrens, Thomas Brabletz	423
14	Expression of L1-CAM and ADAM10 in Human Colon Cancer Cells Induces Metastasis 2007 ·Cancer Research ·Nancy Gavert, Michal Sheffer, Shani Raveh, Simone Spaderna, Michael Shtutman, Thomas Brabletz, Francis Barany, Phillip Paty, Daniel A. Notterman, Eytan Domany, Avri Ben‐Ze'ev	167
15	Migrating cancer stem cells: An integrated concept of malignant tumor progression. 2006 ·Cancer Epidemiology and Prevention Biomarkers ·Thomas Brabletz	7
16	ILEI: A cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells 2006 ·Cancer Cell ·Thomas Waerner, (unknown), (unknown), (unknown), Annamaria Gal, Thomas Brabletz, Martin Schreiber, Martin Jechlinger, Hartmut Beug	150
17	β-Catenin Up-Regulates the Expression of the Urokinase Plasminogen Activator in Human Colorectal Tumors 2004 ·Cancer Research ·Elke Hiendlmeyer, Susanne Regus, (unknown), Falk Hlubek, (unknown), Arno Dimmler, Claudia Koch, Claudia Knoll, Moniek van Beest, Ute Reuning, Thomas Brabletz, Thomas Kirchner, Andreas Jung	76
18	Down-Regulation of the Homeodomain Factor Cdx2 in Colorectal Cancer by Collagen Type I 2004 ·Cancer Research ·Thomas Brabletz, Simone Spaderna, J. Kolb, Falk Hlubek, Gerhard Faller, Christiane J. Bruns, Andreas Jung, (unknown), Isabelle Duluc, Claire Domon–Dell, Thomas Kirchner, Jean‐Noël Freund	113
19	DRO1, a Gene Down-regulated by Oncogenes, Mediates Growth Inhibition in Colon and Pancreatic Cancer Cells 2004 ·Journal of Biological Chemistry ·Guido T. Bommer, (unknown), (unknown), (unknown), Sören T. Eichhorst, Thomas Brabletz, Gang Hu, Thomas Fröhlich, Georg J. Arnold, (unknown), Burkhard Göke, Eric R. Fearon, Frank T. Kolligs	49
20	Mismatch repair deficiency in sporadic synchronous colorectal cancer. 2001 ·PubMed ·Wolfgang M. Brueckl, (unknown), Thomas Brabletz, Klaus Guenther, Andreas Jung, (unknown), Gunther H. Wiest, Thomas Kirchner, Werner Hohenberger, Eckhart G. Hahn, Axel Wein	12

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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