Naohiro Inohara

42.5k total citations · 18 hit papers
154 papers, 32.3k citations indexed

About

Naohiro Inohara is a scholar working on Molecular Biology, Immunology and Infectious Diseases. According to data from OpenAlex, Naohiro Inohara has authored 154 papers receiving a total of 32.3k indexed citations (citations by other indexed papers that have themselves been cited), including 82 papers in Molecular Biology, 76 papers in Immunology and 25 papers in Infectious Diseases. Recurrent topics in Naohiro Inohara's work include Immune Response and Inflammation (55 papers), Cell death mechanisms and regulation (34 papers) and Gut microbiota and health (24 papers). Naohiro Inohara is often cited by papers focused on Immune Response and Inflammation (55 papers), Cell death mechanisms and regulation (34 papers) and Gut microbiota and health (24 papers). Naohiro Inohara collaborates with scholars based in United States, Japan and United Kingdom. Naohiro Inohara's co-authors include Gabriel Núñez, Yasunori Ogura, Felicia F. Chen, Mathias Chamaillard, Nobuhiko Kamada, Mizuho Hasegawa, Mary Benedict, Koichi Fukase, Grace Chen and Takeyoshi Koseki and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Naohiro Inohara

151 papers receiving 31.8k citations

Hit Papers

A frameshift mutation in NOD2 associated with susceptibil... 1998 2026 2007 2016 2001 2005 2003 2013 2001 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    2001 3.7k citations Naohiro Inohara, Gabriel Núñez et al. profile →
  2. Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract
    2005 1.4k citations Naohiro Inohara, Gabriel Núñez et al. Science profile →
  3. Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2
    2003 1.3k citations Naohiro Inohara, Koichi Fukase et al. Journal of Biological Chemistry profile →
  4. Control of pathogens and pathobionts by the gut microbiota
    2013 1.2k citations Nobuhiko Kamada, Grace Chen et al. Nature Immunology profile →
  5. Nod2, a Nod1/Apaf-1 Family Member That Is Restricted to Monocytes and Activates NF-κB
    2001 1.1k citations Naohiro Inohara, Gabriel Núñez et al. Journal of Biological Chemistry profile →
  6. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
    2003 1.0k citations Yasuo Horie, Junya Masumoto et al. Nature Immunology profile →
  7. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages
    2006 949 citations Luigi Franchi, Amal O. Amer et al. Nature Immunology profile →
  8. Caspases: the proteases of the apoptotic pathway
    1998 929 citations Gabriel Núñez, Naohiro Inohara et al. profile →
  9. NODs: intracellular proteins involved in inflammation and apoptosis
    2003 803 citations Naohiro Inohara, Gabriel Núñez profile →
  10. NOD-LRR PROTEINS: Role in Host-Microbial Interactions and Inflammatory Disease
    2005 768 citations Naohiro Inohara, Christine McDonald et al. profile →
  11. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
    2002 731 citations Naohiro Inohara, Gabriel Núñez et al. profile →
  12. NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease
    2014 620 citations Roberta Caruso, Naohiro Inohara et al. profile →
  13. Mechanisms of inflammation-driven bacterial dysbiosis in the gut
    2016 606 citations Melody Y. Zeng, Naohiro Inohara et al. profile →
  14. Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB
    1999 606 citations Naohiro Inohara, Gabriel Núñez et al. Journal of Biological Chemistry profile →
  15. Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA
    2006 568 citations Thirumala‐Devi Kanneganti, Mathilde Body–Malapel et al. Journal of Biological Chemistry profile →
  16. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis
    2020 459 citations Yizu Jiao, Merritt Gillilland et al. profile →
  17. Staphylococcus δ-toxin induces allergic skin disease by activating mast cells
    2013 409 citations Mizuho Hasegawa, Naohiro Inohara et al. profile →
  18. An experimental murine model to study periodontitis
    2018 261 citations Julie T. Marchesan, Mustafa Girnary et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Naohiro Inohara United States 81 15.3k 15.2k 5.4k 5.2k 3.4k 154 32.3k
Volker Brinkmann Germany 91 19.4k 1.3× 23.2k 1.5× 3.2k 0.6× 5.2k 1.0× 3.8k 1.1× 250 45.3k
Lars Eckmann United States 78 8.2k 0.5× 9.8k 0.6× 3.9k 0.7× 3.5k 0.7× 3.7k 1.1× 238 25.5k
Richard S. Blumberg United States 94 11.0k 0.7× 16.4k 1.1× 5.1k 0.9× 5.0k 1.0× 2.7k 0.8× 321 34.0k
Dana J. Philpott Canada 81 8.9k 0.6× 12.5k 0.8× 2.4k 0.5× 4.5k 0.9× 3.1k 0.9× 244 23.6k
Satoshi Uematsu Japan 75 11.2k 0.7× 23.7k 1.6× 2.3k 0.4× 6.9k 1.3× 4.0k 1.2× 218 37.4k
Arturo Zychlinsky Germany 69 11.9k 0.8× 25.2k 1.7× 3.7k 0.7× 4.5k 0.9× 4.8k 1.4× 137 37.0k
Kenya Honda Japan 63 13.6k 0.9× 14.8k 1.0× 2.6k 0.5× 4.1k 0.8× 5.1k 1.5× 129 29.9k
R. Balfour Sartor United States 87 16.4k 1.1× 7.1k 0.5× 8.9k 1.6× 5.8k 1.1× 5.3k 1.6× 336 32.0k
Jay K. Kolls United States 101 8.5k 0.6× 21.6k 1.4× 2.9k 0.5× 8.5k 1.6× 5.8k 1.7× 477 40.9k
Stephen E. Girardin Canada 72 8.4k 0.6× 11.7k 0.8× 2.2k 0.4× 4.9k 0.9× 2.3k 0.7× 179 21.9k

Countries citing papers authored by Naohiro Inohara

Since Specialization
Citations

This map shows the geographic impact of Naohiro Inohara's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Naohiro Inohara with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Naohiro Inohara more than expected).

Fields of papers citing papers by Naohiro Inohara

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Naohiro Inohara. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Naohiro Inohara. The network helps show where Naohiro Inohara may publish in the future.

Co-authorship network of co-authors of Naohiro Inohara

This figure shows the co-authorship network connecting the top 25 collaborators of Naohiro Inohara. A scholar is included among the top collaborators of Naohiro Inohara based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Naohiro Inohara. Naohiro Inohara is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Heras, Manuel M. Gómez de las, Elisa Carrasco, Naohiro Inohara, et al.. (2025). CD4 T cell therapy counteracts inflammaging and senescence by preserving gut barrier integrity. Science Immunology. 10(110). eadv0985–eadv0985.
2.
Raynaud, Céline, Valentina Strohmeier, Jana Neuber, et al.. (2025). Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface. Blood. 145(18). 2025–2040.
3.
Sanidad, Katherine Z., Aparna Ananthanarayanan, Tingting Li, et al.. (2024). Gut bacteria–derived serotonin promotes immune tolerance in early life. Science Immunology. 9(93). eadj4775–eadj4775. 43 indexed citations
4.
Lo, Bernard C., Ilona Kryczek, Jiali Yu, et al.. (2024). Microbiota-dependent activation of CD4 + T cells induces CTLA-4 blockade–associated colitis via Fcγ receptors. Science. 383(6678). 62–70. 40 indexed citations
5.
Kuffa, Peter, Joseph M. Pickard, Austin Campbell, et al.. (2023). Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont. Cell Host & Microbe. 31(12). 2007–2022.e12. 28 indexed citations
6.
Ribeiro, Apoena Aguiar, Yizu Jiao, Mustafa Girnary, et al.. (2022). Oral biofilm dysbiosis during experimental periodontitis. Molecular Oral Microbiology. 37(6). 256–265. 10 indexed citations
7.
Chen, Lixing, Yali Zhai, Yisheng Wang, et al.. (2021). Altering the Microbiome Inhibits Tumorigenesis in a Mouse Model of Oviductal High-Grade Serous Carcinoma. Cancer Research. 81(12). 3309–3318. 27 indexed citations
8.
Bamba, Shigeki, Osamu Inatomi, Atsushi Nishida, et al.. (2021). Relationship between the gut microbiota and bile acid composition in the ileal mucosa of Crohn’s disease. Intestinal Research. 20(3). 370–380. 19 indexed citations
9.
Caruso, Roberta, Eric C. Martens, Nobuhiko Kamada, et al.. (2019). A specific gene-microbe interaction drives the development of Crohn’s disease–like colitis in mice. Science Immunology. 4(34). 123 indexed citations
10.
Kim, Yun‐Gi, Sang‐Uk Seo, Joseph M. Pickard, et al.. (2017). Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens. Science. 356(6335). 315–319. 191 indexed citations
11.
Kamada, Nobuhiko, Grace Chen, Naohiro Inohara, & Gabriel Núñez. (2013). Control of pathogens and pathobionts by the gut microbiota. Nature Immunology. 14(7). 685–690. 1173 indexed citations breakdown →
12.
Hasegawa, Mizuho, Beate Heissig, Koichi Hattori, et al.. (2011). Tumor Necrosis Factor Receptor-associated Factor (TRAF) 2 Controls Homeostasis of the Colon to Prevent Spontaneous Development of Murine Inflammatory Bowel Disease. Journal of Biological Chemistry. 286(20). 17879–17888. 32 indexed citations
13.
Kawasaki, Akiko, et al.. (2008). Synthesis of Diaminopimelic Acid Containing Peptidoglycan Fragments and Tracheal Cytotoxin (TCT) and Investigation of Their Biological Functions. Chemistry - A European Journal. 14(33). 10318–10330. 45 indexed citations
14.
Park, Jong‐Hwan, Yun‐Gi Kim, Christine McDonald, et al.. (2007). RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but Not TLRs. The Journal of Immunology. 178(4). 2380–2386. 425 indexed citations
15.
Masumoto, Junya, Kangkang Yang, Sooryanarayana Varambally, et al.. (2006). Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo. The Journal of Experimental Medicine. 203(1). 203–213. 176 indexed citations
16.
Franchi, Luigi, Amal O. Amer, Mathilde Body–Malapel, et al.. (2006). Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages. Nature Immunology. 7(6). 576–582. 949 indexed citations breakdown →
17.
Hasegawa, Mizuho, Ryu Imamura, Takeshi Kinoshita, et al.. (2006). ASC-mediated NF-κB Activation Leading to IL-8 Production Requires Caspase-8 and Is Inhibited by CLARP. 2003. 117.
18.
Fukase, Koichi, Seiichi Inamura, Akiko Kawasaki, et al.. (2005). Mechanism of Immunostimulating Action of Peptidoglycan, Investigation with Synthetic Partial Structures. 2004. 109–112. 1 indexed citations
19.
20.
Wu, Dayang, Herschel Wallen, Naohiro Inohara, & Gabriel Núñez. (1997). Interaction and Regulation of the Caenorhabditis elegans Death Protease CED-3 by CED-4 and CED-9. Journal of Biological Chemistry. 272(34). 21449–21454. 112 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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