Daniel Oehlrich

1.9k citations

36 papers · 1.3k indexed · h-index 21

Impact in

Pharmaceutical Science top 2%
- Fluorine in Organic Chemistry
Organic Chemistry top 5%
- Catalytic C–H Functionalization Methods
- Synthesis and Catalytic Reactions
- Catalytic Cross-Coupling Reactions

Papers in

Pharmaceutical Science 6
- Fluorine in Organic Chemistry 6
Toxicology 2

Co-authors: Harrie J. M. Gijsen Frederik Rombouts Gary A. Molander Marc Presset Andrés A. Trabanco Hana Prokopcová Didier Berthelot Gary Tresadern
Journals: Journal of Medicinal Chemistry (6 papers)The Journal of Organic Chemistry (6 papers)Bioorganic & Medicinal Chemistry Letters (5 papers)Organic Letters (3 papers)ACS Medicinal Chemistry Letters (2 papers)
Partner nations: Belgium United States United Kingdom

In The Last Decade

Daniel Oehlrich

36 papers receiving 1.3k citations

Peers

Countries citing papers authored by Daniel Oehlrich

Since Specialization

Citations

This map shows the geographic impact of Daniel Oehlrich's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Daniel Oehlrich with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Daniel Oehlrich more than expected).

Fields of papers citing papers by Daniel Oehlrich

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Daniel Oehlrich. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Daniel Oehlrich. The network helps show where Daniel Oehlrich may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Daniel Oehlrich, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Daniel Oehlrich Line = papers co-authored together Daniel Oehlrich links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structural basis for the oligomerization-facilitated NLRP3 activation Nature Communications ·Xiaodi Yu, Rosalie Matico, Shagufta Rasool, Dhruv Chauhan, 和弘上松, Karolien Grauwen, Javier Suárez, Beth Pietrak, S. Menaka, Yanting Yin, Gary Tresadern, Laura Pérez‐Benito, Erik Lindahl, Astrid Bottelbergs, Daniel Oehlrich, Nina Van Opdenbosch, Sujata Sharma	2024	25
2	Mutated Toll-like receptor 9 increases Alzheimer’s disease risk by compromising innate immunity protection Molecular Psychiatry ·Rita Cacace, Teguh Lingga Mukti, Saima Kafeel, Arjan Buist, W. Cao, Anne Sieben, Patrick Cras, Rik Vandenberghe, Peter Paul De Deyn, Daniel Oehlrich, An De Bondt, Sebastiaan Engelborghs, Diederik Moechars, Christine Van Broeckhoven	2023	7
3	Reductive site-selective atypical C , Z -type/N2-C2 cleavage allows C-terminal protein amidation Science Advances ·И. В. Савельева, Andrew M. Giltrap, Yibo Zeng, Adriana Luketić, Ricardo Trigueros, Daniel Oehlrich, Andrew J. Baldwin, Daniel C. Anthony, Shabaz Mohammed, Benjamin G. Davis	2022	7
4	Scaffold Hopping to Imidazo[1,2-a]pyrazin-8-one Positive Allosteric Modulators of Metabotropic Glutamate 2 Receptor ACS Omega ·Ana Isabel de Lucas, Juan A. Vega, P.G. Wester, María Lourdes Linares, Gary Tresadern, Hilde Lavreysen, Daniel Oehlrich, Andrés A. Trabanco, José M. Cid	2021	2
5	A Brain-Penetrant and Bioavailable Pyrazolopiperazine BACE1 Inhibitor Elicits Sustained Reduction of Amyloid β In Vivo ACS Medicinal Chemistry Letters ·Aldo Peschiulli, Daniel Oehlrich, Michiel Van Gool, Nigel Austin, Sven Van Brandt, 小原正明, Jeremy Alistair David Tagg, Ann Vos, Gary Tresadern, Frederik Rombouts, Gregor J. Macdonald, Diederik Moechars, Andrés A. Trabanco, Harrie J. M. Gijsen	2021	7
6	Post-translational insertion of boron in proteins to probe and modulate function Nature Chemical Biology ·И. В. Савельева, Patrick G. Isenegger, Brian Josephson, Ricardo Trigueros, Lukas Lercher, Daniel Oehlrich, D. Flemming Hansen, Shabaz Mohammed, Andrew J. Baldwin, Véronique Gouverneur, Benjamin G. Davis	2021	27
7	Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines Journal of the American Chemical Society ·M.R. Menezes, David M. H. Ascough, Francesco Ibba, Anna Chiara Vicini, Alberto Fontana, Kirsten E. Christensen, Aldo Peschiulli, Daniel Oehlrich, Antonio Misale, Andrés A. Trabanco, Robert S. Paton, Gabriele Pupo, Véronique Gouverneur	2020	54
8	3,3-Difluoro-3,4,5,6-tetrahydropyridin-2-amines: Potent and permeable BACE-1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Aldo Peschiulli, Daniel Oehlrich, Frederik Rombouts, Ann Vos, Harrie J. M. Gijsen	2020	2
9	Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads ACS Medicinal Chemistry Letters ·Daniel Oehlrich, Aldo Peschiulli, Gary Tresadern, Michiel Van Gool, Juan A. Vega, Ana Isabel de Lucas, 陆俊生, Hana Prokopcová, Nigel Austin, Sven Van Brandt, 小原正明, Jeremy Alistair David Tagg, Ann Vos, Frederik Rombouts, Gregor J. Macdonald, Dieder Moechars, Harrie J. M. Gijsen, Andrés A. Trabanco	2019	26
10	Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis iScience ·Luke A. Miles, S.J. Hermans, Gabriela A. N. Crespi, Jonathan H. Gooi, Larissa Doughty, Tracy L. Nero, A. I. Kedrov, Andreas Ebneth, Berthold Wroblowski, Daniel Oehlrich, Andrés A. Trabanco, M. Rives, Inès Royaux, Nancy C. Hancock, Michael W. Parker	2019	64
11	Bench-Stable Transfer Reagent Facilitates the Generation of Trifluoromethyl-sulfonimidamides The Journal of Organic Chemistry ·M. Mohib Ur Rehman, I. Seiffge-Krenke, Feti Munika Sakti, Paul E. Brennan, Andrés A. Trabanco, Daniel Oehlrich	2018	25
12	Optimization of 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors Toward a Clinical Candidate Journal of Medicinal Chemistry ·Harrie J. M. Gijsen, 陆俊生, Jeremy Alistair David Tagg, Anil Kumar A. S., Gregor J. Macdonald, I. Seiffge-Krenke, Daniel Oehlrich, Hana Prokopcová, Frederik Rombouts, 小原正明, Andrés A. Trabanco, Sven Van Brandt, 賴昭君, Michiel Van Gool, Nigel Austin, Herman Borghys, 노덕삼, Diederik Moechars	2018	11
13	The Synthesis of Trifluoromethyl-sulfonimidamides from Sulfinamides The Journal of Organic Chemistry ·Charlotte S. Richards‐Taylor, I. Seiffge-Krenke, Feti Munika Sakti, Andrés A. Trabanco, Daniel Oehlrich	2017	36
14	Acylguanidine Beta Secretase 1 Inhibitors: A Combined Experimental and Free Energy Perturbation Study Journal of Chemical Theory and Computation ·Henrik Keränen, Laura Pérez‐Benito, كامل على كامل, Francisca Delgado, Thomas Steinbrecher, Daniel Oehlrich, Herman van Vlijmen, Andrés A. Trabanco, Gary Tresadern	2017	63
15	Industrial medicinal chemistry insights: neuroscience hit generation at Janssen Drug Discovery Today ·Gary Tresadern, Frederik Rombouts, Daniel Oehlrich, Gregor J. Macdonald, Andrés A. Trabanco	2017	7
16	The evolution of amidine-based brain penetrant BACE1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Daniel Oehlrich, Hana Prokopcová, Harrie J. M. Gijsen	2014	125
17	Anilinotriazoles as potent gamma secretase modulators Bioorganic & Medicinal Chemistry Letters ·José Villatoro, François Bischoff, Didier Berthelot, Jeremy Alistair David Tagg, Daniel Oehlrich, SAMUEL SOARES CARDOSO BRAGA, Gregor J. Macdonald, Maryan Mohamad Nor, Serge Pieters, Frederik Rombouts, Sven Van Brandt, Sophia paes de barba, 小原正明, Andrés A. Trabanco, Gary Tresadern, Tongfei Wu, Herman Borghys, Marc Mercken, Chantal Masungi, Harrie J. M. Gijsen	2014	12
18	Design and synthesis of bicyclic heterocycles as potent γ-secretase modulators Bioorganic & Medicinal Chemistry Letters ·Daniel Oehlrich, Frederik Rombouts, Didier Berthelot, François Bischoff, Emi okazaki, SAMUEL SOARES CARDOSO BRAGA, Gregor J. Macdonald, Marc Mercken, 小原正明, Andrés A. Trabanco, Gary Tresadern, Sven Van Brandt, José Villatoro, Tongfei Wu, Harrie J. M. Gijsen	2013	15
19	Scaffold hopping from pyridones to imidazo[1,2-a]pyridines. New positive allosteric modulators of metabotropic glutamate 2 receptor Bioorganic & Medicinal Chemistry Letters ·Gary Tresadern, José M. Cid, Gregor J. Macdonald, Juan A. Vega, Ana Isabel de Lucas, José Ángel Eguiguren Iraola, W. Fricke, María Lourdes Linares, Daniel Oehlrich, Hilde Lavreysen, Young-San Lin, Andrés A. Trabanco	2009	58
20	Synthesis of 5-hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-ones: selective antagonists of muscarinic (M3) receptors Organic & Biomolecular Chemistry ·Ben Bradshaw, Paul Evans, E. L. Elmassry, Alan T. L. Lee, Marcus Twellmann, Daniel Oehlrich, Eric J. Thomas, Patel Hasu, Xinqiang Zou, Kenneth J. Broadley, Liangjun Zheng, Michael King Yung Chung	2008	15

About Daniel Oehlrich

Daniel Oehlrich is a scholar working on Pharmaceutical Science, Toxicology, Computational Theory and Mathematics, Organic Chemistry and Biological Psychiatry, having authored 36 papers that have together received 1.3k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (9 papers), Chemical Synthesis and Analysis (8 papers), Catalytic Cross-Coupling Reactions (7 papers), Alzheimer's disease research and treatments (7 papers), Fluorine in Organic Chemistry (6 papers), Neuroscience and Neuropharmacology Research (5 papers), Receptor Mechanisms and Signaling (5 papers) and Cholinesterase and Neurodegenerative Diseases (4 papers). The work is most often cited by research in Pharmaceutical Science (159 citations), Organic Chemistry (711 citations), Computational Theory and Mathematics (226 citations), Biological Psychiatry (27 citations) and Pharmacology (162 citations). Daniel Oehlrich has collaborated with scholars based in Belgium, United States and United Kingdom. Frequent co-authors include Harrie J. M. Gijsen, Frederik Rombouts, Gary A. Molander, Marc Presset, Andrés A. Trabanco, Hana Prokopcová, Didier Berthelot, Gary Tresadern, Jesús Alcázar and Nicolas Fleury‐Brégeot. Their work appears in journals such as Journal of Medicinal Chemistry, The Journal of Organic Chemistry, Bioorganic & Medicinal Chemistry Letters, Organic Letters and ACS Medicinal Chemistry Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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