Dennis Dean

5.4k citations

66 papers · 2.0k indexed · h-index 25

Impact in

Pharmacology top 0.5%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
Pharmaceutical Science top 2%
- Fluorine in Organic Chemistry

Papers in

Pharmacology 9
- Pharmacogenetics and Drug Metabolism 8
Pharmaceutical Science 5
- Fluorine in Organic Chemistry 5

Co-authors: Albert Padwa Wei Tang George A. Doss Matthew P. Braun Thomas A. Baillie Charles S. Elmore David G. Melillo Conrad E. Raab
Journals: Drug Metabolism and Disposition (11 papers)Bioorganic & Medicinal Chemistry Letters (6 papers)The Journal of Organic Chemistry (4 papers)Journal of the American Chemical Society (3 papers)Journal of Pharmacology and Experimental Therapeutics (2 papers)
Partner nations: United States Japan Switzerland

In The Last Decade

Dennis Dean

65 papers receiving 1.9k citations

Peers

Countries citing papers authored by Dennis Dean

Since Specialization

Citations

This map shows the geographic impact of Dennis Dean's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dennis Dean with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dennis Dean more than expected).

Fields of papers citing papers by Dennis Dean

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dennis Dean. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dennis Dean. The network helps show where Dennis Dean may publish in the future.

Co-authors

The 25 scholars most cited alongside Dennis Dean, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dennis Dean Line = papers co-authored together Dennis Dean links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	First‐in‐human safety, tolerability, and pharmacokinetic results of DFV890, an oral low‐molecular‐weight NLRP3 inhibitor Clinical and Translational Science ·X. Liu, E.H. Alagnide, Emilie Voltz, Ülrike Sommer, Elaine Tritto, 岸上龍平, Xiaoxi Liu, Parasar Pal, Maria Velinova, William S. Denney, Yunlin Fu, Anthony W. Opipari, Dennis Dean, G. Junge	2024	27
2	Double-blind crossover study to assess potential differences in cytochrome P450 3A4 activity in healthy subjects receiving ondansetron plus dexamethasone, with and without aprepitant Cancer Chemotherapy and Pharmacology ·S. Aubrey Stoch, Cynthia Gargano, J L Valentine, Matthew P. Braun, M. Gail Murphy, M. Zellner, Anup Majumdar, Edward Pequignot, Keith Gottesdiener, Kevin J. Petty, Deborah Panebianco, Dennis Dean, Walter K. Kraft, Howard Greenberg	2010	13
3	Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans Drug Metabolism and Disposition ·Sanjeev Kumar, 阿部聡, Georgy Hartmann, Jiashun Liu, Arthur Bergman, Muhammad Zaid Ramadhan, Jonathan Z. Ho, E.N. Shulga, Becerra Juan Luis, Matthew P. Braun, Bindhu V. Karanam, Dennis Dean, Isaias Noel Gendrano, B.L. Ioffee, John A. Wagner, Rajesh Krishna	2009	33
4	Identification and characterization of a selective radioligand for melanin-concentrating hormone 1-receptor (MCH1R) Bioorganic & Medicinal Chemistry Letters ·Masahiko Ito, Toshihiro Sakamoto, Takao Suzuki, Shinichiro Egashira, Minoru Moriya, Akane Ishihara, Hisashi Iwaasa, Hiroko Matsushita, Kawakib Mohammed Alotaibi, Michael A. Wallace, Dennis Dean, Nagaaki Sato, Shigeru Tokita, Akio Kanatani	2009	7
5	Multiple strategies for the preparation of a sulfur-35 labeled NPC1L1 radioligand Bioorganic & Medicinal Chemistry Letters ·B. Chevarin, Matthew P. Braun, Joseph F. Leone, Peter Lin, Robert J. DeVita, Margarita García‐Calvo, Gorman H.V., JeanMarie Lisnock, Dennis Dean	2009	5
6	Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys Drug Metabolism and Disposition ·阿部聡, Georgy Hartmann, Qing Chen, P David, Scott A. Bradley, George A. Doss, Steven Whitham, Jonathan Z. Ho, Matthew P. Braun, Dennis Dean, Wei Tang, Sanjeev Kumar	2009	27
7	Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Scott D. Edmondson, Lan Wei, Jinyou Xu, Jackie Shang, Shiyao Xu, Jianmei Pang, Ashok Chaudhary, Dennis Dean, Huaibing He, Barbara Leiting, Kathryn A. Lyons, Reshma A. Patel, Sangita B. Patel, Giovanna Scapin, Joseph K. Wu, Maria Beconi, Nancy A. Thornberry, Ann E. Weber	2008	95
8	In Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver Preparations Drug Metabolism and Disposition ·Ying Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis Dean, Thomas A. Baillie, Wei Tang	2007	34
9	Transport of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin by Human Organic Anion Transporter 3, Organic Anion Transporting Polypeptide 4C1, and Multidrug Resistance P-glycoprotein Journal of Pharmacology and Experimental Therapeutics ·Xiaoyan Chu, Kelly Bleasby, Jocelyn Yabut, Xiaoxin Cai, Grace Chan, Michael J. Hafey, Shiyao Xu, Arthur Bergman, Matthew P. Braun, Dennis Dean, Raymond Evers	2007	143
10	Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand Bioorganic & Medicinal Chemistry Letters ·S. E. Wolkenberg, Zhijian Zhao, Marianna Kapitskaya, Andrea L. Webber, Konstantin Petrukhin, Yui S. Tang, Dennis Dean, George D. Hartman, Craig W. Lindsley	2006	27
11	Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans Drug Metabolism and Disposition ·Christopher J. Kochansky, BakerThomas, 草深竹志, Antonio Luherini, Michael A. Wallace, Dennis Dean, E.N. Shulga, Kenneth C. Lasseter, Jules I. Schwartz, Stella Vincent, Ronald B. Franklin, John A. Wagner	2006	5
12	The syntheses of [¹⁴C] and [¹³C₂,¹⁵N₃]aprepitant Journal of Labelled Compounds and Radiopharmaceuticals ·Charles S. Elmore, Dennis Dean, Yong Zhang, C. Williams	2004	4
13	Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist European Journal of Pharmacology ·Richard W. Ransom, C. Meacham Harrell, Duane R. Reiss, 哲也三澤, Raymond S.L. Chang, J. Fred Hess, Patricia Miller, Stacey O’Malley, Bridget Magni, Priya Kunapuli, Dai‐Shi Su, J. M. Vela, Michael A. Wallace, Conrad E. Raab, E.N. Shulga, Dennis Dean, Douglas J. Pettibone, Roger Freidinger, Mark G. Bock	2004	18
14	The Changing Environment of Graduate and Postdoctoral Training in Drug Metabolism: Viewpoints from Academia, Industry, and Government Drug Metabolism and Disposition ·Jeffrey Stevens, Dennis Dean, Peter C. Preusch, Maria Almira Correia	2003	2
15	Evaluation of ubiquinone concentration and mitochondrial function relative to cerivastatin-induced skeletal myopathy in rats Toxicology and Applied Pharmacology ·William H. Schaefer, Thia Zakiyah Oktiviarni, 勝則木幡, H. Schrijver-Davelaar, Lori Mixson, Dennis Dean, Conrad E. Raab, Nathan X. Yu, George R. Lankas, Clay B. Frederick	2003	105
16	Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma Drug Metabolism and Disposition ·Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis Dean, Grace K. Poon, Wang Zhengting, John R. Strauss, Shuet‐Hing Lee Chiu, Neil R. Curtis, Jason Elliott, Ute Gerhard, Karen L Locker, Denise Morrison, Russell J. Mortishire‐Smith, Steven R. Thomas, Alan P. Watt, David C. Evans	2002	6
17	A nonpeptide oxytocin receptor antagonist radioligand highly selective for human receptors European Journal of Pharmacology ·Wei Lemaire, Julie A. O’Brien, Maryann Burno, Ashok Chaudhary, Dennis Dean, Peter D. Williams, Roger Freidinger, Douglas J. Pettibone, David L. Williams	2002	13
18	Ivermectin and Nodulisporic Acid Receptors in Drosophila melanogaster Contain Both γ-Aminobutyric Acid-Gated Rdl and Glutamate-Gated GluClα Chloride Channel Subunits Biochemistry ·Steven W. Ludmerer, Vivien A. Warren, Brande S. Williams, Yingcong Zheng, David Hunt, 栄治鈴木, Michael A. Wallace, Ashok Chaudhary, Franklin M Leow, Peter T. Meinke, Dennis Dean, María L. García, Doris Cully, McHardy M. Smith	2002	87
19	The Potential for CYP2D6 Inhibition Screening Using a Novel Scintillation Proximity Assay-Based Approach SLAS DISCOVERY ·Jea-Hyung Lim, Donald E. Slaughter, Franklin M Leow, Gregory J. Gatto, Egnon Jacques Hougbénou-Houngla, Yuan Tao Zhang, 初男小暮, Corina Panaitescu, Dennis Dean, Andrea F. Glogger	2001	13
20	Vinylogous carbinolamine tumor inhibitors. 24. Synthesis, chemistry, and antineoplastic activity of .alpha.-halopyridinium salts: potential pyridone prodrugs of acylated vinylogous carbinolamine tumor inhibitors. Journal of Medicinal Chemistry ·Wayne K. Anderson, Dennis Dean, Volodumir Stompel	1990	46

About Dennis Dean

Dennis Dean is a scholar working on Pharmacology, Pharmaceutical Science, Organic Chemistry, Biochemistry and Cellular and Molecular Neuroscience, having authored 66 papers that have together received 2.0k indexed citations. Recurring topics across this work include Neuropeptides and Animal Physiology (10 papers), Cyclopropane Reaction Mechanisms (9 papers), Receptor Mechanisms and Signaling (9 papers), Pharmacogenetics and Drug Metabolism (8 papers), Chemical Synthesis and Analysis (8 papers), Drug Transport and Resistance Mechanisms (7 papers), Eicosanoids and Hypertension Pharmacology (5 papers) and Fluorine in Organic Chemistry (5 papers). The work is most often cited by research in Pharmacology (487 citations), Pharmaceutical Science (171 citations), Organic Chemistry (571 citations), Endocrine and Autonomic Systems (120 citations) and Oncology (381 citations). Dennis Dean has collaborated with scholars based in United States, Japan and Switzerland. Frequent co-authors include Albert Padwa, Wei Tang, George A. Doss, Matthew P. Braun, Thomas A. Baillie, Charles S. Elmore, David G. Melillo, Conrad E. Raab, Kwan Leung and Paul G. Pearson. Their work appears in journals such as Drug Metabolism and Disposition, Bioorganic & Medicinal Chemistry Letters, The Journal of Organic Chemistry, Journal of the American Chemical Society and Journal of Pharmacology and Experimental Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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