Julie A. O’Brien

2.0k citations

30 papers · 1.3k indexed · h-index 16

Cellular and Molecular Neuroscience top 2%
- Neuroscience and Neuropharmacology Research 16
Biological Psychiatry top 10%
Toxicology top 5%
- Bioactive Compounds and Antitumor Agents 2
Molecular Biology top 10%
- Receptor Mechanisms and Signaling 14
- Pharmacological Receptor Mechanisms and Effects 3
Endocrine and Autonomic Systems top 10%
Biochemistry
- Amino Acid Enzymes and Metabolism 3
Social Psychology
- Neuroendocrine regulation and behavior 3
Experimental and Cognitive Psychology
- Sleep and related disorders 2
Oncology
- Drug Transport and Resistance Mechanisms 2

Co-authors: David L. Williams P. Jeffrey Conn Cyrille Sur Marlene A. Jacobson Wei Lemaire Craig W. Lindsley Douglas J. Pettibone Gene G. Kinney
Cited by: Cellular and Molecular Neuroscience Biological Psychiatry Toxicology
Journals: Proceedings of the National Academy of Sciences (1 paper)Annals of the New York Academy of Sciences (2 papers)Journal of Medicinal Chemistry (2 papers)
Partner nations: United States United Kingdom Poland

In The Last Decade

Julie A. O’Brien

30 papers receiving 1.3k citations

Peers

Countries citing papers authored by Julie A. O’Brien

Since Specialization

Citations

This map shows the geographic impact of Julie A. O’Brien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Julie A. O’Brien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Julie A. O’Brien more than expected).

Fields of papers citing papers by Julie A. O’Brien

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Julie A. O’Brien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Julie A. O’Brien. The network helps show where Julie A. O’Brien may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Julie A. O’Brien, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Julie A. O’Brien Line = papers co-authored together Julie A. O’Brien links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery of 4-arylquinoline-2-carboxamides, highly potent and selective class of mGluR2 negative allosteric modulators: From HTS to activity in animal models Bioorganic & Medicinal Chemistry Letters ·Youheng Shu,Tracy L. Diamond,James C. Hershey,Shaei Huang,Brian C. Magliaro,Julie A. O’Brien,Kelly-Ann S. Schlegel,Vanita Puri,Victor N. Uebele,Jason M. Uslaner,Cheng Wang,Antonella Converso	2020	4
2	Identification of MK-8133: An orexin-2 selective receptor antagonist with favorable development properties Bioorganic & Medicinal Chemistry Letters ·Scott D. Kuduk,Jason W. Skudlarek,Christina N. DiMarco,Joseph G. Bruno,Mark H. Pausch,Julie A. O’Brien,Tamara D. Cabalu,Joanne Stevens,Joseph Brunner,Pamela L. Tannenbaum,Susan L. Garson,Alan T. Savitz,C. Meacham Harrell,Anthony L. Gotter,Christopher J. Winrow,John J. Renger,Paul J. Coleman	2015	15
3	Breast-Conserving Surgery in Bilateral Breast Cancer Annals of Surgical Oncology ·Julie A. O’Brien,Alice Y. Ho,G. Paul Wright,Michelle Stempel,Sujata Patil,Kate Krause,Monica Morrow,Mary L. Gemignani	2015	19
4	Synthesis and evaluation of carbon-linked analogs of dual orexin receptor antagonist filorexant Bioorganic & Medicinal Chemistry Letters ·Scott D. Kuduk,Jason W. Skudlarek,Christina N. Di Marco,Joseph G. Bruno,Mark Pausch,Julie A. O’Brien,Tamara D. Cabalu,Joanne Stevens,Joseph Brunner,Pamela L. Tannenbaum,Anthony L. Gotter,Christopher J. Winrow,John J. Renger,Paul J. Coleman	2014	7
5	Fleur-de-lis Panniculectomy After Bariatric Surgery Annals of Plastic Surgery ·Julie A. O’Brien,Genevieve Broderick,Zachary M. Hurwitz,Richard D. Montilla,John Castle,Raymond M. Dunn,Mustafa Akyürek,Janice F. Lalikos	2011	8
6	The M1 Muscarinic Receptor Allosteric Agonists AC-42 and 1-[1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one Bind to a Unique Site Distinct from the Acetylcholine Orthosteric Site Molecular Pharmacology ·Marlene A. Jacobson,Constantine Kreatsoulas,Danette Pascarella,Julie A. O’Brien,Cyrille Sur	2010	24
7	3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts Bioorganic & Medicinal Chemistry Letters ·Edward J. Brnardic,Mark E. Fraley,R. M. Garbaccio,M. E. Layton,John M. Sanders,Chris Culberson,Marlene A. Jacobson,Brian C. Magliaro,Pete H. Hutson,Julie A. O’Brien,Sarah L. Huszar,Jason M. Uslaner,Kerry L. Fillgrove,Cuyue Tang,Yuhsin Kuo,Sylvie M. Sur,George D. Hartman	2010	30
8	Differential effects of the mGluR5 positive allosteric modulator CDPPB in the cortex and striatum following repeated administration Neuropharmacology ·Sophie Parmentier‐Batteur,Julie A. O’Brien,Scott M. Doran,Shannon Nguyen,Rosemarie B. Flick,Jason M. Uslaner,Hank Chen,Eleftheria N. Finger,Theresa M. Williams,Marlene A. Jacobson,Pete H. Hutson	2010	50
9	Discovery of N-{[1-(propylsulfonyl)-4-pyridin-2-ylpiperidin-4-yl]methyl}benzamides as novel, selective and potent GlyT1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Zhijian Zhao,William Leister,Julie A. O’Brien,Wei Lemaire,David L. Williams,Marlene A. Jacobson,Cyrille Sur,Gene G. Kinney,D. J. PETTIBONE,Philip R. Tiller,Sheri Smith,George D. Hartman,Craig W. Lindsley,S. E. Wolkenberg	2009	16
10	Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides Bioorganic & Medicinal Chemistry Letters ·Zhijian Zhao,Julie A. O’Brien,Wei Lemaire,David L. Williams,Marlene A. Jacobson,Cyrille Sur,D. J. PETTIBONE,Philip R. Tiller,Sheri Smith,George D. Hartman,S. E. Wolkenberg,Craig W. Lindsley	2006	12
11	Challenges in the development of mGluR5 positive allosteric modulators: The discovery of CPPHA Bioorganic & Medicinal Chemistry Letters ·Zhijian Zhao,David D. Wisnoski,Julie A. O’Brien,Wei Lemaire,David L. Williams,Marlene A. Jacobson,Marion Wittman,Sookhee Ha,Hervé Schaffhauser,Cyrille Sur,D. J. PETTIBONE,Mark E. Duggan,P. Jeffrey Conn,George D. Hartman,Craig W. Lindsley	2006	58
12	A Novel Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Has in Vivo Activity and Antipsychotic-Like Effects in Rat Behavioral Models Journal of Pharmacology and Experimental Therapeutics ·Gene G. Kinney,Julie A. O’Brien,Wei Lemaire,Maryann Burno,Denise Bickel,Michelle K. Clements,Tsing‐Bau Chen,David D. Wisnoski,Craig W. Lindsley,Philip R. Tiller,Sheri Smith,Marlene A. Jacobson,Cyrille Sur,Mark E. Duggan,Douglas J. Pettibone,P. Jeffrey Conn,David L. Williams	2005	229
13	A Novel Selective Allosteric Modulator Potentiates the Activity of Native Metabotropic Glutamate Receptor Subtype 5 in Rat Forebrain Journal of Pharmacology and Experimental Therapeutics ·Julie A. O’Brien,Wei Lemaire,Marion Wittmann,Marlene A. Jacobson,Sookhee Ha,David D. Wisnoski,Craig W. Lindsley,Hervé Schaffhauser,Blake A. Rowe,Cyrille Sur,Mark E. Duggan,Douglas J. Pettibone,P. Jeffrey Conn,David L. Williams	2004	132
14	A Family of Highly Selective Allosteric Modulators of the Metabotropic Glutamate Receptor Subtype 5 Molecular Pharmacology ·Julie A. O’Brien,Wei Lemaire,Tsing‐Bau Chen,Raymond S.L. Chang,Marlene A. Jacobson,Sookhee Ha,Craig W. Lindsley,Hervé Schaffhauser,Cyrille Sur,Douglas J. Pettibone,P. Jeffrey Conn,David L. Williams	2003	170
15	Modulation of Inhibitory Transmission in the Rat Globus Pallidus by Activation of mGluR4 Annals of the New York Academy of Sciences ·Michael J. Marino,Ornella Valenti,Julie A. O’Brien,David R. Williams,P. Jeffrey Conn	2003	16
16	Difference in mGluR5 Interaction between Positive Allosteric Modulators from Two Structural Classes Annals of the New York Academy of Sciences ·David L. Williams,Julie A. O’Brien,Wei Lemaire,Tsing‐Bau Chen,Raymond S.L. Chang,Marlene A. Jacobson,Sookhee Ha,David D. Wisnoski,Craig W. Lindsley,Cyrille Sur,Mark E. Duggan,Douglas J. Pettibone,P. Jeffrey Conn	2003	2
17	A nonpeptide oxytocin receptor antagonist radioligand highly selective for human receptors European Journal of Pharmacology ·Wei Lemaire,Julie A. O’Brien,Maryann Burno,Ashok Chaudhary,Dennis Dean,Peter D. Williams,Roger Freidinger,Douglas J. Pettibone,David L. Williams	2002	13
18	Pharmacology of L-744,453, a novel nonpeptidyl endothelin antagonist Life Sciences ·David L. Williams,Kathryn L. Murphy,Nancy A. Nolan,Julie A. O’Brien,Edward V. Lis,Douglas J. Pettibone,Bradley V. Clineschmidt,Stephen M. Krause,Daniel F. Veber,Elizabeth M. Naylor,Prasun K. Chakravarty,Thomas F. Walsh,Dale M Dhanoa,Anna Chent,Scott W. Bagley,Kenneth J. Fitch,William J. Greenlee	1996	6
19	Characterization of the human oxytocin receptor stably expressed in 293 human embryonic kidney cells Life Sciences ·Jeffrey R. Jasper,C. Meacham Harrell,Julie A. O’Brien,Douglas J. Pettibone	1995	38
20	Synthesis and evaluation of 2-pyridinone derivatives as HIV-1 specific reverse transcriptase inhibitors. 1. Phthalimidoalkyl and -alkylamino analogs Journal of Medicinal Chemistry ·J. M. HOFFMAN,John Wai,Craig Thomas,Rhonda B. Levin,Julie A. O’Brien,Mark E. Goldman	1992	44

About Julie A. O’Brien

Julie A. O’Brien is a scholar working on Cellular and Molecular Neuroscience, Toxicology and Endocrine and Autonomic Systems, having authored 30 papers that have together received 1.3k indexed citations. Recurring topics across this work include Neuroscience and Neuropharmacology Research (16 papers), Receptor Mechanisms and Signaling (14 papers), Amino Acid Enzymes and Metabolism (3 papers), Pharmacological Receptor Mechanisms and Effects (3 papers), Neuroendocrine regulation and behavior (3 papers), Bioactive Compounds and Antitumor Agents (2 papers), Sleep and related disorders (2 papers) and Drug Transport and Resistance Mechanisms (2 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (971 citations), Biological Psychiatry (41 citations) and Toxicology (45 citations). Julie A. O’Brien has collaborated with scholars based in United States, United Kingdom and Poland. Frequent co-authors include David L. Williams, P. Jeffrey Conn, Cyrille Sur, Marlene A. Jacobson, Wei Lemaire, Craig W. Lindsley, Douglas J. Pettibone, Gene G. Kinney, David D. Wisnoski and Mark E. Duggan. Their work appears in journals such as Proceedings of the National Academy of Sciences, Annals of the New York Academy of Sciences and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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