Xiaoyan Chu

10.1k citations

90 papers · 5.0k indexed · h-index 40

Impact in

Pharmacology top 0.05%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
- Antibiotics Pharmacokinetics and Efficacy
Oncology top 0.5%
- Drug Transport and Resistance Mechanisms

Papers in

Pharmacology 26
- Pharmacogenetics and Drug Metabolism 23
Oncology 66
- Drug Transport and Resistance Mechanisms 66

Co-authors: Raymond Evers Kelly Bleasby Yuichi Sugiyama Yukio Kato Jashvant D. Unadkat Aleksandra Galetin Yurong Lai Grace Chan
Journals: Clinical Pharmacology & Therapeutics (25 papers)Drug Metabolism and Disposition (15 papers)Journal of Pharmacology and Experimental Therapeutics (6 papers)The AAPS Journal (3 papers)Journal of Pharmaceutical Sciences (2 papers)
Partner nations: United States Japan China

In The Last Decade

Xiaoyan Chu

89 papers receiving 5.0k citations

Peers

Countries citing papers authored by Xiaoyan Chu

Since Specialization

Citations

This map shows the geographic impact of Xiaoyan Chu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xiaoyan Chu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xiaoyan Chu more than expected).

Fields of papers citing papers by Xiaoyan Chu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xiaoyan Chu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xiaoyan Chu. The network helps show where Xiaoyan Chu may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Xiaoyan Chu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Xiaoyan Chu Line = papers co-authored together Xiaoyan Chu links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Predicting OCT2 / MATEs ‐Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium) Clinical Pharmacology & Therapeutics ·Satoshi Asano, Aleksandra Galetin, Yoshiko Tomita, Kathleen M. Giacomini, Xiaoyan Chu, Xinning Yang, Toshimichi Nakamura, Hiroyuki Kusuhara, Yuichi Sugiyama	2025	2
2	Physiologically‐based pharmacokinetic model‐based translation of OATP1B‐mediated drug–drug interactions from coproporphyrin I to probe drugs Clinical and Translational Science ·Tatsuki Mochizuki, Yasunori Aoki, Takashi Yoshikado, Kenta Yoshida, Yurong Lai, Hideki Hirabayashi, Yoshiyuki Yamaura, Kevin Rockich, Kunal S. Taskar, Tadayuki Takashima, Xiaoyan Chu, Maciej J. Zamek‐Gliszczynski, 吉岡真佐樹, Kazuya Maeda, Kenichi Furihata, Yuichi Sugiyama, Hiroyuki Kusuhara	2022	24
3	Clinical Relevance of Hepatic and Renal P‐gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective Clinical Pharmacology & Therapeutics ·Kunal S. Taskar, Xinning Yang, Sibylle Neuhoff, Mitesh Patel, Kenta Yoshida, Mary F. Paine, Kim L. R. Brouwer, Xiaoyan Chu, Yuichi Sugiyama, Jack Cook, Joseph W. Polli, Imad Hanna, Yurong Lai, Maciej J. Zamek‐Gliszczynski, (unknown)	2022	23
4	Selection of an Optimal In Vitro Model to Assess P-gp Inhibition: Comparison of Vesicular and Bidirectional Transcellular Transport Inhibition Assays Drug Metabolism and Disposition ·Jocelyn Yabut, Robert Houle, Shubing Wang, Andy Liaw, 和田貴宏, Suman J. Mathur, Alexander Normatov, Xiaoyan Chu	2022	5
5	Education metaverse: Innovations and challenges of the new generation of Internet education formats Xuesong Zhai, Xiaoyan Chu, Minjuan Wang, Ziwei Zhang, A. Caburet	2022	7
6	Prediction of Transporter-Mediated Rosuvastatin Hepatic Uptake Clearance and Drug Interaction in Humans Using Proteomics-Informed REF Approach Drug Metabolism and Disposition ·Vineet Kumar, 武爽, Kazuya Ishida, Laurent Salphati, Cornelis E. C. A. Hop, Christopher Rowbottom, Guangqing Xiao, Yurong Lai, Anita Mathias, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Hari Krishna Y, 裕一城, Scott Heyward, Jashvant D. Unadkat	2020	27
7	Intestinal P‐gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications Clinical Pharmacology & Therapeutics ·Maciej J. Zamek‐Gliszczynski, Mitesh Patel, Xinning Yang, Justin D. Lutz, Xiaoyan Chu, Kim L. R. Brouwer, Yurong Lai, Caroline A. Lee, Sibylle Neuhoff, Mary F. Paine, Yuichi Sugiyama, Kunal S. Taskar, Aleksandra Galetin	2020	39
8	The role and regulatory mechanism of autophagy in hippocampal nerve cells of piglet damaged by deoxynivalenol Toxicology in Vitro ·Xichun Wang, Xiaoyan Chu, Li Cao, Jie Zhao, Lei Zhu, Sajid Ur Rahman, Zhen Hu, Yafei Zhang, Shibin Feng, Yu Li, Jinjie Wu	2020	18
9	Positron Emission Tomography Imaging of [¹¹C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporin A Clinical Pharmacology & Therapeutics ·Sarah Billington, Steven C. Shoner, Scott D. Lee, Kindra Clark‐Snustad, Kamolchanok Ngamkham, David H. Lewis, Mark Muzi, D. Albuger, Jean Lee, Tot Bui Nguyen, Vineet Kumar, Kazuya Ishida, Laigao Chen, Xiaoyan Chu, Yurong Lai, Laurent Salphati, Cornelis E. C. A. Hop, Guangqing Xiao, Mingxiang Liao, Jashvant D. Unadkat	2019	50
10	Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood–Brain Barrier Measured by Quantitative Targeted Proteomics Clinical Pharmacology & Therapeutics ·Sarah Billington, Laurent Salphati, Cornelis E. C. A. Hop, Xiaoyan Chu, Raymond Evers, 苗瑞芬, Christopher Rowbottom, Yurong Lai, Guangqing Xiao, W. Griffith Humphreys, Tot Bui Nguyen, Bhagwat Prasad, Jashvant D. Unadkat	2019	60
11	Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug‐Drug Interaction Evaluation: Perspectives From the International Transporter Consortium Clinical Pharmacology & Therapeutics ·Xiaoyan Chu, Mingxiang Liao, Hong Shen, Kenta Yoshida, Arik A. Zur, Vikram Arya, Aleksandra Galetin, Kathleen M. Giacomini, Imad Hanna, Hiroyuki Kusuhara, Yurong Lai, David Rodrigues, Yuichi Sugiyama, Maciej J. Zamek‐Gliszczynski, Lei Zhang	2018	161
12	Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance Clinical Pharmacology & Therapeutics ·Maciej J. Zamek‐Gliszczynski, Mitchell E. Taub, Paresh P. Chothe, Xiaoyan Chu, Kathleen M. Giacomini, Richard B. Kim, Adrian S. Ray, Sophie L. Stocker, Jashvant D. Unadkat, Matthias Wittwer, Cindy Q. Xia, Sook Wah Yee, Lei Zhang, Yan Zhang	2018	157
13	Interspecies Variability in Expression of Hepatobiliary Transporters across Human, Dog, Monkey, and Rat as Determined by Quantitative Proteomics Drug Metabolism and Disposition ·Li Wang, Bhagwat Prasad, Laurent Salphati, Xiaoyan Chu, Anshul Gupta, Cornelis E. C. A. Hop, Raymond Evers, Jashvant D. Unadkat	2014	143
14	Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins Drug Metabolism and Disposition ·Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Isao Nishizima, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loïc Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A.B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel, Nico Scheer	2014	30
15	The metabolism and disposition of a potent inhibitor of hepatitis C virus NS3/4A protease Xenobiotica ·Edith Monteagudo, Massimiliano Fonsi, Xiaoyan Chu, Kelly Bleasby, Raymond Evers, Vincenzo Pucci, Maria Vittoria Orsale, Simona Cianetti, Marco Ferrara, Steven J. Harper, R. Laufer, Michael Rowley, Vincenzo Summa	2010	12
16	Metabolism and Renal Elimination of Gaboxadol in Humans: Role of UDP-Glucuronosyltransferases and Transporters Pharmaceutical Research ·Xiaoyan Chu, Yuexia Liang, Xiaoxin Cai, 森永宗史, BakerThomas, Kelem Kassahun, Magang Shou, Matthew P. Braun, George A. Doss, M. Reza Anari, Raymond Evers	2008	16
17	Characterization of Mice Lacking the Multidrug Resistance Protein Mrp2 (Abcc2) Journal of Pharmacology and Experimental Therapeutics ·Xiaoyan Chu, John R. Strauss, Wenqiang Zu, Jing Li, Deborah J. Newton, Xiaoxin Cai, Regina W. Wang, Jocelyn Yabut, Dylan P. Hartley, David C. Evans, Raymond Evers	2006	105
18	Transport of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate by the Multidrug Resistance Proteins MRP1, MRP2, and MRP3 Journal of Pharmacology and Experimental Therapeutics ·Xiaoyan Chu, Xiao-Lu Zou, Matthew P. Braun, Balázs Sarkadi, David Evans, Raymond Evers	2004	80
19	Active Efflux of CPT-11 and Its Metabolites in Human KB-Derived Cell Lines Journal of Pharmacology and Experimental Therapeutics ·Xiaoyan Chu, Hiroshi Suzuki, Chimene Mendel Schuster, Yukio Kato, Shin‐ichi Akiyama, Yuichi Sugiyama	1999	76
20	Multiplicity of biliary excretion mechanisms for the camptothecin derivative irinotecan (CPT-11), its metabolite SN-38, and its glucuronide: role of canalicular multispecific organic anion transporter and P-glycoprotein Cancer Chemotherapy and Pharmacology ·Yuichi Sugiyama, Yukio Kato, Xiaoyan Chu	1998	83

About Xiaoyan Chu

Xiaoyan Chu is a scholar working on Pharmacology, Oncology, Pediatrics, Perinatology and Child Health, Clinical Biochemistry and Biochemistry, having authored 90 papers that have together received 5.0k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (66 papers), Pharmacological Effects and Toxicity Studies (36 papers), Pharmacogenetics and Drug Metabolism (23 papers), HIV/AIDS drug development and treatment (10 papers), Liver Disease Diagnosis and Treatment (7 papers), Cancer therapeutics and mechanisms (6 papers), Pregnancy and Medication Impact (6 papers) and Mycotoxins in Agriculture and Food (6 papers). The work is most often cited by research in Pharmacology (1.7k citations), Oncology (3.2k citations), Pediatrics, Perinatology and Child Health (1.8k citations), Biochemistry (228 citations) and Hepatology (223 citations). Xiaoyan Chu has collaborated with scholars based in United States, Japan and China. Frequent co-authors include Raymond Evers, Kelly Bleasby, Yuichi Sugiyama, Yukio Kato, Yuichi Sugiyama, Jashvant D. Unadkat, Aleksandra Galetin, Yurong Lai, Grace Chan and Jocelyn Yabut. Their work appears in journals such as Clinical Pharmacology & Therapeutics, Drug Metabolism and Disposition, Journal of Pharmacology and Experimental Therapeutics, The AAPS Journal and Journal of Pharmaceutical Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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