William S. Denney

2.1k total citations · 1 hit paper
35 papers, 1.4k citations indexed

About

William S. Denney is a scholar working on Molecular Biology, Surgery and Physiology. According to data from OpenAlex, William S. Denney has authored 35 papers receiving a total of 1.4k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Molecular Biology, 8 papers in Surgery and 8 papers in Physiology. Recurrent topics in William S. Denney's work include Metabolism and Genetic Disorders (5 papers), Diet and metabolism studies (4 papers) and Platelet Disorders and Treatments (4 papers). William S. Denney is often cited by papers focused on Metabolism and Genetic Disorders (5 papers), Diet and metabolism studies (4 papers) and Platelet Disorders and Treatments (4 papers). William S. Denney collaborates with scholars based in United States, Belgium and United Kingdom. William S. Denney's co-authors include Scott L. Diamond, Manash Chatterjee, Aoife M. Brennan, Marja Puurunen, Caroline Kurtz, Huiyan Jing, Vincent M. Isabella, Mark R. Charbonneau, David A. Wagner and Jonathan W. Kotula and has published in prestigious journals such as Blood, Cancer Research and Biophysical Journal.

In The Last Decade

William S. Denney

34 papers receiving 1.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans

2019 280 citations Caroline Kurtz, Yves Millet et al. Science Translational Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
William S. Denney United States	20	581	210	191	181	131	35	1.4k
Rudolf Oehler Austria	28	744 1.3×	97 0.5×	219 1.1×	389 2.1×	72 0.5×	81	2.3k
S. Tam Hong Kong	30	768 1.3×	179 0.9×	179 0.9×	206 1.1×	301 2.3×	98	2.4k
Patricia L. Fernández Panama	18	999 1.7×	188 0.9×	68 0.4×	515 2.8×	68 0.5×	43	2.3k
Li Zhao China	22	505 0.9×	84 0.4×	66 0.3×	72 0.4×	34 0.3×	99	1.3k
Sonia Moretti Italy	33	1.3k 2.2×	70 0.3×	223 1.2×	150 0.8×	28 0.2×	98	3.3k
Landon Wilson United States	26	879 1.5×	48 0.2×	129 0.7×	329 1.8×	21 0.2×	84	2.1k
Ilana Nathan Israel	24	793 1.4×	244 1.2×	160 0.8×	186 1.0×	17 0.1×	96	1.9k
Margaret M. Allaman United States	23	967 1.7×	44 0.2×	320 1.7×	175 1.0×	23 0.2×	48	1.9k
Frank Streit Germany	23	600 1.0×	70 0.3×	271 1.4×	89 0.5×	18 0.1×	55	1.8k
Jing Guan China	25	817 1.4×	153 0.7×	178 0.9×	245 1.4×	18 0.1×	119	2.0k

Countries citing papers authored by William S. Denney

Since Specialization

Citations

This map shows the geographic impact of William S. Denney's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William S. Denney with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William S. Denney more than expected).

Fields of papers citing papers by William S. Denney

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William S. Denney. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William S. Denney. The network helps show where William S. Denney may publish in the future.

Co-authorship network of co-authors of William S. Denney

This figure shows the co-authorship network connecting the top 25 collaborators of William S. Denney. A scholar is included among the top collaborators of William S. Denney based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William S. Denney. William S. Denney is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Voltz, Emilie, Ülrike Sommer, Elaine Tritto, et al.. (2024). First‐in‐human safety, tolerability, and pharmacokinetic results of DFV890, an oral low‐molecular‐weight NLRP3 inhibitor. Clinical and Translational Science. 17(5). e13789–e13789. 27 indexed citations

Perreault, Mylène, Michael J. James, Sean L. Cotton, et al.. (2024). The live biotherapeutic SYNB1353 decreases plasma methionine via directed degradation in animal models and healthy volunteers. Cell Host & Microbe. 32(3). 382–395.e10. 23 indexed citations

Leu, Jocelyn H., et al.. (2024). Pharmacokinetics and pharmacodynamics across infusion rates of intravenously administered nipocalimab: results of a phase 1, placebo-controlled study. Frontiers in Neuroscience. 18. 1302714–1302714. 11 indexed citations

Vockley, Jerry, Neal Sondheimer, Marja Puurunen, et al.. (2023). Efficacy and safety of a synthetic biotic for treatment of phenylketonuria: a phase 2 clinical trial. Nature Metabolism. 5(10). 1685–1690. 41 indexed citations

Charbonneau, Mark R., et al.. (2021). Development of a mechanistic model to predict synthetic biotic activity in healthy volunteers and patients with phenylketonuria. Communications Biology. 4(1). 898–898. 13 indexed citations

Puurunen, Marja, Jerry Vockley, Stephanie Sacharow, et al.. (2021). Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study. Nature Metabolism. 3(8). 1125–1132. 105 indexed citations

Langston, Vernon C., Robert W. Wills, William S. Denney, et al.. (2021). Pharmacokinetics and pharmacodynamics of intravenous continuous rate infusion and repeated intramuscular administration of dexmedetomidine in standing horses. Journal of Veterinary Pharmacology and Therapeutics. 44(4). 533–543. 2 indexed citations

Abuqayyas, Lubna, et al.. (2020). AKR-001, an Fc-FGF21 Analog, Showed Sustained Pharmacodynamic Effects on Insulin Sensitivity and Lipid Metabolism in Type 2 Diabetes Patients. Cell Reports Medicine. 1(4). 100057–100057. 102 indexed citations

Kurtz, Caroline, Yves Millet, Marja Puurunen, et al.. (2019). An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans. Science Translational Medicine. 11(475). 280 indexed citations breakdown →

10.

Sharma, Raman, John Litchfield, Karen Atkinson, et al.. (2014). Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator. Drug Metabolism and Disposition. 42(11). 1926–1939. 15 indexed citations

11.

Conrado, Daniela J., William S. Denney, Danny Chen, & Kaori Ito. (2014). An updated Alzheimer’s disease progression model: incorporating non-linearity, beta regression, and a third-level random effect in NONMEM. Journal of Pharmacokinetics and Pharmacodynamics. 41(6). 581–598. 26 indexed citations

12.

Peng, Joanna, William S. Denney, Bret J. Musser, et al.. (2014). A Semi-mechanistic Model for the Effects of a Novel Glucagon Receptor Antagonist on Glucagon and the Interaction Between Glucose, Glucagon, and Insulin Applied to Adaptive Phase II Design. The AAPS Journal. 16(6). 1259–1270. 15 indexed citations

13.

Denney, William S., et al.. (2012). Children Will Eat the Strangest Things. Pediatric Emergency Care. 28(8). 731–734. 53 indexed citations

14.

Reitman, Marc L., Victor Dishy, William S. Denney, et al.. (2011). Pharmacokinetics and Pharmacodynamics of MK‐5046, a Bombesin Receptor Subtype‐3 (BRS‐3) Agonist, in Healthy Patients. The Journal of Clinical Pharmacology. 52(9). 1306–1316. 38 indexed citations

15.

Palcza, John, William S. Denney, Tae Hyung Han, et al.. (2009). Blockade of Capsaicin-Induced Dermal Vasodilatation (CIDV) by MK-3207, a Calcitonin-Gene Related Peptide (CGRP) Receptor Antagonist for Acute Treatment of Migraine. Cephalalgia. 2 indexed citations

16.

Sinclair, Simon, Stefanie A. Kane, Bart Van der Schueren, et al.. (2009). Inhibition of capsaicin‐induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK‐0974). British Journal of Clinical Pharmacology. 69(1). 15–22. 70 indexed citations

17.

Gibson, Christopher R., et al.. (2009). Prediction of Phase I single-dose pharmacokinetics using recombinant cytochromes P450 and physiologically based modelling. Xenobiotica. 39(9). 637–648. 18 indexed citations

18.

Gosalia, Dhaval N., William S. Denney, Cleo M. Salisbury, Jonathan A. Ellman, & Scott L. Diamond. (2006). Functional phenotyping of human plasma using a 361‐fluorogenic substrate biosensing microarray. Biotechnology and Bioengineering. 94(6). 1099–1110. 28 indexed citations

19.

Lo, Ken Sin, William S. Denney, & Scott L. Diamond. (2005). Stochastic Modeling of Blood Coagulation Initiation. Pathophysiology of Haemostasis and Thrombosis. 34(2-3). 80–90. 47 indexed citations

20.

Kadash-Edmondson, Kathryn E., William S. Denney, & Scott L. Diamond. (2005). Neutrophil-Bead Collision Assay: Pharmacologically Induced Changes in Membrane Mechanics Regulate the PSGL-1/P-Selectin Adhesion Lifetime. Biophysical Journal. 89(5). 3603–3614. 30 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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