David E. Paschon

6.8k citations

27 papers · 3.8k indexed · 2 hit papers · h-index 16

Business and International Management top 1%
Aging top 2%
Molecular Biology top 2%
- CRISPR and Genetic Engineering 19
- RNA Interference and Gene Delivery 6
- Pluripotent Stem Cells Research 4
- Advanced biosensing and bioanalysis techniques 3
- Viral Infectious Diseases and Gene Expression in Insects 2
Genetics top 1%
- Virus-based gene therapy research 10
Cell Biology top 5%
Oncology
- CAR-T cell therapy research 5
Cellular and Molecular Neuroscience
- Genetic Neurodegenerative Diseases 2

Co-authors: Philip D. Gregory Michael C. Holmes Edward J. Rebar Jeffrey C. Miller Fyodor D. Urnov Sarah J. Hinkley Jianbin Wang Danny F. Xia
Cited by: Business and International Management Aging Molecular Biology
Journals: Blood (7 papers)Molecular Therapy (3 papers)Nature (2 papers)
Partner nations: United States United Kingdom Spain

In The Last Decade

David E. Paschon

26 papers receiving 3.7k citations

Hit Papers

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Peers

Countries citing papers authored by David E. Paschon

Since Specialization

Citations

This map shows the geographic impact of David E. Paschon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David E. Paschon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David E. Paschon more than expected).

Fields of papers citing papers by David E. Paschon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David E. Paschon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David E. Paschon. The network helps show where David E. Paschon may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David E. Paschon, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David E. Paschon Line = papers co-authored together David E. Paschon links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets Molecular Therapy ·Anthony Conway,Matthew Mendel,Kenneth H. Kim,P. (Priani) Priani,Stephanie Shamoon,Lei Zhang,Jeffrey C. Miller,Russell C. DeKelver,David E. Paschon,Barbara L. Mui,Paulo J.C. Lin,Ying K. Tam,Junyang Chen,T.E. Redelmeier,Michael C. Holmes,Gary Lee	2019	69
2	Diversifying the structure of zinc finger nucleases for high-precision genome editing Nature Communications ·David E. Paschon,Stephanie Lussier,Changfeng Jing,Danny F. Xia,N. M. Sharova,Sarah J. Hinkley,A. Sampson,Stephen C.-T. Lam,Adam James Waite,Jennifer Smith‐Davis,Nimisha Gandhi,Firdosius Nickolaus Malagam,Deepak P. Patil,David A. Shivak,Murugan Shri Ganesh Kumar,Michael C. Holmes,Lei Zhang,Jeffrey C. Miller,Edward J. Rebar	2019	85
3	Enhancing gene editing specificity by attenuating DNA cleavage kinetics Nature Biotechnology ·Jeffrey C. Miller,Deepak P. Patil,Danny F. Xia,正剛野口,Friedrich Fauser,Hunter W. Richards,David A. Shivak,Woo Young Lee,Sarah J. Hinkley,A. Sampson,Stephen C.-T. Lam,Andreas Reik,Yuanyue Zhou,David E. Paschon,Patrick Li,Changfeng Jing,Gary Lee,Lei Zhang,Edward J. Rebar	2019	40
4	Humanized Mouse Model of HIV-1 Latency with Enrichment of Latent Virus in PD-1 ⁺ and TIGIT ⁺ CD4 T Cells Journal of Virology ·George N. Llewellyn,Eduardo Seclén,Stephen W. Wietgrefe,Siyu Liu,Morgan Chateau,Hua Pei,Katherine Perkey,Matthew D. Marsden,Sarah J. Hinkley,David E. Paschon,Michael C. Holmes,Jerome A. Zack,Stan G. Louie,Ashley T. Haase,Paula M. Cannon	2019	21
5	Gene Correction of iPSCs from a Wiskott-Aldrich Syndrome Patient Normalizes the Lymphoid Developmental and Functional Defects Stem Cell Reports ·Tamara Laskowski,Paul Landauer,Rasoul Pourebrahim,Chao Ma,Zhenya Ni,Yong-yi Xu,Ana M. Crane,Xuan Shirley Li,Wei‐Ching Liao,Manuel L. Gonzalez‐Garay,José C. Segovia,David E. Paschon,Edward J. Rebar,Michael C. Holmes,Dan S. Kaufman,Bart Vandekerckhove,Brian R. Davis	2016	36
6	Mammalian interspecies substitution of immune modulatory alleles by genome editing Scientific Reports ·Simon Lillico,Chris Proudfoot,Tim King,Wenfang Tan,Lei Zhang,Gaurav Thakur,David E. Paschon,Edward J. Rebar,Fyodor D. Urnov,Alan J. Mileham,David G. McLaren,Bruce Whitelaw	2016	84
7	641. Highly Efficient, ZFN-Driven Knockout of Surface Expression of the T-Cell Receptor and HLA Class I Proteins in Human T-Cells for Enhancing Allogeneic Adoptive Cell Therapies Molecular Therapy ·Murugan Shri Ganesh Kumar,Peiqi Liu,Nimisha Gandhi,Jennifer Smith‐Davis,Andreas Reik,Stephen C.-T. Lam,Sarah J. Hinkley,Jeffrey C. Miller,David E. Paschon,Lei Zhang,Edward J. Rebar,Michael C. Holmes	2016	1
8	A7 Drug discovery approach for rare neurological diseases: using novel zinc finger protein technology to develop potential therapy for huntington’s disease Journal of Neurology Neurosurgery & Psychiatry ·Roxana Ronquillo-Murrieta,Vivian W. Choi,Gabriel Matías Lorenz,M. Mendil,Omar L. Francone,David Thomson,Bryan Zeitler,Steven Froelich,Qi Yu,David E. Paschon,Jeffrey C. Miller,Mary Austin,Edward J. Rebar,Fyodor D. Urnov,Philip D. Gregory,千穂南	2016	1
9	Targeted Correction and Restored Function of the CFTR Gene in Cystic Fibrosis Induced Pluripotent Stem Cells Stem Cell Reports ·Ana M. Crane,Philipp Krämer,Mehmet Ali ELÇİN,Wook Joon Chung,Xuan Shirley Li,Manuel L. Gonzalez‐Garay,Finn Hawkins,Wei Liao,Jitendra Kumar Patel,Sangbum Choi,Jianbin Wang,北沢宏和,David E. Paschon,Dmitry Guschin,Philip D. Gregory,Darrell N. Kotton,Michael C. Holmes,Eric J. Sorscher,Brian R. Davis	2015	153
10	ZFN-Mediated Gene Targeting at the Albumin Locus in Liver Results in Therapeutic Levels of Human FIX in Mice and Non-Human Primates Blood ·Thomas Wechsler,Kathleen Meyer,S. Kaye Spratt,Judith S. Greengard,Yolanda Santiago,Scott Sproul,Richard Surosky,David E. Paschon,Richard Wayte,Dale Ando,Geoff Nichol,Edward J. Rebar,Michael C. Holmes	2015	3
11	LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction Neurobiology of Disease ·Laurie H. Sanders,Josée Laganière,Oliver Cooper,Sally K. Mak,Spuler,Ying Huang,David E. Paschon,Cristina Espana,Ramya Sundararajan,Fyodor D. Urnov,J. William Langston,Philip D. Gregory,H. Steve Zhang,J. Timothy Greenamyre,Ole Isacson,Birgitt Schüle	2013	216
12	ZFN Mediated Targeting Of Albumin “Safe Harbor” Results In Therapeutic Levels Of Human Factor VIII In a Mouse Model Of Hemophilia A Blood ·Xavier M. Anguela,Rajiv P. Sharma,Yannick Doyon,Thomas Wechsler,David E. Paschon,Robert J. Davidson,Shangzhen Zhou,Philip D. Gregory,Michael C. Holmes,Edward J. Rebar,Katherine A. High	2013	2
13	In Vivo Genome Editing of Liver Albumin for Therapeutic Gene Expression: Rescue of Hemophilic Mice Via Integration of Factor 9 Blood ·Xavier M. Anguela,Rajiv P. Sharma,Yannick Doyon,Sunnie Wong,David E. Paschon,Hojun Li,Virginia Haurigot,Robert J. Davidson,Shangzhen Zhou,Philip D. Gregory,Michael C. Holmes,Edward J. Rebar,Katherine A. High	2012	2
14	Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cellsbreakdown → Nature ·Kosuke Yusa,S. Tamir Rashid,Hélène Strick‐Marchand,Ignacio Varela,spp. are reported,David E. Paschon,Elena Miranda,A. Ordóñez,Nicholas R. F. Hannan,Foad J. Rouhani,Sylvie Darche,Graeme Alexander,Stefan J. Marciniak,Noemi Fusaki,Mamoru Hasegawa,Michael C. Holmes,James P. Di Santo,David A. Lomas,Allan Bradley,Ludovic Vallier	2011	472
15	In vivo genome editing restores haemostasis in a mouse model of haemophilia Nature ·Hojun Li,Virginia Haurigot,Yannick Doyon,Tianjian Li,Sunnie Wong,Anand Bhagwat,Nirav Malani,Xavier M. Anguela,Rajiv P. Sharma,Helzi Angelina,Samuel L. Murphy,Jonathan D. Finn,Fayaz R. Khazi,Shangzhen Zhou,David E. Paschon,Edward J. Rebar,Frederic D. Bushman,Philip D. Gregory,Michael C. Holmes,Katherine A. High	2011	411
16	Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases Proceedings of the National Academy of Sciences ·John J. Young,Jennifer M. Cherone,Yannick Doyon,Irina Ankoudinova,Farhoud Faraji,Andrew Lee,Catherine Ngo,Dmitry Guschin,David E. Paschon,Jeffrey C. Miller,Lei Zhang,Edward J. Rebar,Philip D. Gregory,Fyodor D. Urnov,Richard M. Harland,Bryan Zeitler	2011	114
17	Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells Nature Cell Biology ·Jeffrey B. Doyon,Bryan Zeitler,Jackie Cheng,Aaron Cheng,Jennifer M. Cherone,Yolanda Santiago,Andrew Lee,Thuy D. Vo,Yannick Doyon,Jeffrey C. Miller,David E. Paschon,Lei Zhang,Edward J. Rebar,Philip D. Gregory,Fyodor D. Urnov,David G. Drubin	2011	186
18	An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease Journal of Neuroscience ·Josée Laganière,Adrian P. Kells,F. Tomas,Dmitry Guschin,David E. Paschon,Xiangdong Meng,Lauren Fong,S Gnensch,Edward J. Rebar,Philip D. Gregory,Krystof S. Bankiewicz,John Forsayeth,J. Linek	2010	56
19	A TALE nuclease architecture for efficient genome editingbreakdown → Nature Biotechnology ·Jeffrey C. Miller,Siyuan Tan,Kaoru Kitao,Kyle A. Barlow,Jianbin Wang,Danny F. Xia,Xiangdong Meng,David E. Paschon,Elo Leung,Sarah J. Hinkley,清光浅野,Kevin Hua,Irina Ankoudinova,Gregory J. Cost,Fyodor D. Urnov,千穂南,Michael C. Holmes,Lei Zhang,Philip D. Gregory,Edward J. Rebar	2010	1580
20	Construction of Protein Fragment Complementation Libraries Using Incremental Truncation Methods in enzymology on CD-ROM/Methods in enzymology ·David E. Paschon,Marc Ostermeier	2004	7

About David E. Paschon

David E. Paschon is a scholar working on Genetics, Molecular Biology, Virology, Oncology and Cellular and Molecular Neuroscience, having authored 27 papers that have together received 3.8k indexed citations. Recurring topics across this work include CRISPR and Genetic Engineering (19 papers), Virus-based gene therapy research (10 papers), RNA Interference and Gene Delivery (6 papers), CAR-T cell therapy research (5 papers), Pluripotent Stem Cells Research (4 papers), Advanced biosensing and bioanalysis techniques (3 papers), Viral Infectious Diseases and Gene Expression in Insects (2 papers) and Genetic Neurodegenerative Diseases (2 papers). The work is most often cited by research in Business and International Management (196 citations), Aging (134 citations), Molecular Biology (3.3k citations), Genetics (1.2k citations) and Cell Biology (227 citations). David E. Paschon has collaborated with scholars based in United States, United Kingdom and Spain. Frequent co-authors include Philip D. Gregory, Michael C. Holmes, Edward J. Rebar, Jeffrey C. Miller, Fyodor D. Urnov, Sarah J. Hinkley, Jianbin Wang, Danny F. Xia, Irina Ankoudinova and Xiangdong Meng. Their work appears in journals such as Blood, Molecular Therapy, Nature, Nature Biotechnology and Stem Cell Reports.

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