Darrell N. Kotton

17.2k citations

143 papers · 8.5k indexed · 3 hit papers · h-index 47

Impact in

Genetics top 0.5%
- Mesenchymal stem cell research
Pulmonary and Respiratory Medicine top 0.5%
- Neonatal Respiratory Health Research

Papers in

Pulmonary and Respiratory Medicine 63
- Neonatal Respiratory Health Research 60
Molecular Biology 82
- Renal and related cancers 38
- Pluripotent Stem Cells Research 29
- Congenital heart defects research 14
- CRISPR and Genetic Engineering 9

Co-authors: Edward E. Morrisey Alan Fine Gustavo Mostoslavsky Ross Summer Laertis Ikonomou George J. Murphy Finn Hawkins Cesar Sommer
Journals: Cell stem cell (11 papers)Stem Cell Reports (9 papers)American Journal of Physiology-Lung Cellular and Molecular Physiology (6 papers)American Journal of Respiratory Cell and Molecular Biology (6 papers)Journal of Visualized Experiments (5 papers)
Partner nations: United States Canada Australia

In The Last Decade

Darrell N. Kotton

134 papers receiving 8.4k citations

Hit Papers

align trajectories log scale

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future 2020 · 243 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 Cell stem cell
2014 Nature Medicine
2010 Nature Medicine

Peers

Countries citing papers authored by Darrell N. Kotton

Since Specialization

Citations

This map shows the geographic impact of Darrell N. Kotton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darrell N. Kotton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darrell N. Kotton more than expected).

Fields of papers citing papers by Darrell N. Kotton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darrell N. Kotton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darrell N. Kotton. The network helps show where Darrell N. Kotton may publish in the future.

Co-authors

The 25 scholars most cited alongside Darrell N. Kotton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Darrell N. Kotton Line = papers co-authored together Darrell N. Kotton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The chromatin remodeling complex PRC2 safeguards cell fate in alveolar epithelial type 2 cells bioRxiv (Cold Spring Harbor Laboratory) ·Helen Warheit-Niemi, Jessie Huang, Kathleen C.S. Cook, Konstantinos A. Alysandratos, Sharlene Fernandes, Payel Basak, Barbara Zhao, Eitan Vilker, Carlos Villacorta-Martín, Amber Elitz, Pushpinder Bawa, Andrea Tóth, Michael J. Herriges, Darrell N. Kotton, William J. Zacharias	2026	0
2	Protocol for the differentiation of human alveolar epithelial type I cells from pluripotent stem cell-derived type II-like cells STAR Protocols ·Claire L. Burgess, Lauren J. Ayers, Kasey Minakin, Konstantinos–Dionysios Alysandratos, Xaralabos Varelas, Darrell N. Kotton	2025	1
3	Topology and Nuclear Size Determine Cell Packing on Growing Lung Spheroids Physical Review X ·Wenhui Tang, Jessie Huang, Adrian F. Pegoraro, James H. Zhang, Y. W. Tang, Darrell N. Kotton, Dapeng Bi, Ming Guo	2025	1
4	Addressing Sex as a Biological Variable in Preclinical Models of Lung Disease: An Official American Thoracic Society Research Statement American Journal of Respiratory and Critical Care Medicine ·Krithika Lingappan, Isaac K. Sundar, Y. S. Prakash, Elizabeth F. Redente, Don D. Sin, MeiLan K. Han, Tim Lahm, Vera P. Krymskaya, Darrell N. Kotton, Hrishikesh S. Kulkarni, Raksha Jain, Mélanie Königshoff, Mansoureh Eghbali, Montserrat C. Anguera, Arthur P. Arnold, Patricia Silveyra, Dawn L. DeMeo	2025	0
5	Lung repair and regeneration: Advanced models and insights into human disease Cell stem cell ·Maria C. Basil, Konstantinos–Dionysios Alysandratos, Darrell N. Kotton, Edward E. Morrisey	2024	20
6	Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection American Journal of Physiology-Lung Cellular and Molecular Physiology ·Ruobing Wang, Adam J. Hume, Mary Lou Beermann, Chantelle Simone-Roach, Jonathan Lindstrom-Vautrin, Jake Le Suer, Jessie Huang, Judith Olejnik, Carlos Villacorta-Martín, Esther Bullitt, Anne Hinds, Mahboobe Ghaedi, S.D. Rollins, Rhiannon B. Werder, Kristine M. Abo, Andrew A. Wilson, Elke Mühlberger, Darrell N. Kotton, Finn Hawkins	2022	13
7	Generation of Airway Epithelial Cell Air-Liquid Interface Cultures from Human Pluripotent Stem Cells Journal of Visualized Experiments ·Andrew Berical, Mary Lou Beermann, Shingo Suzuki, Jake LeSuer, Taylor Matte, Brian J. Davis, Darrell N. Kotton, Finn Hawkins	2022	0
8	CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells Science Advances ·Rhiannon B. Werder, Tao Liu, Kristine M. Abo, Jonathan Lindstrom-Vautrin, Carlos Villacorta-Martín, Jessie Huang, Anne Hinds, Nathan Boyer, Esther Bullitt, Marc Liesa, Edwin K. Silverman, Darrell N. Kotton, Michael H. Cho, Xiaobo Zhou, Andrew A. Wilson	2022	15
9	Culture impact on the transcriptomic programs of primary and iPSC-derived human alveolar type 2 cells JCI Insight ·Konstantinos–Dionysios Alysandratos, Carolina García de Alba, Changfu Yao, Patrizia Pessina, Jessie Huang, Carlos Villacorta-Martín, Olivia T. Hix, Kasey Minakin, Claire L. Burgess, Pushpinder Bawa, Aditi Murthy, Bindu Konda, Michael F. Beers, Barry R. Stripp, Carla F. Kim, Darrell N. Kotton	2022	31
10	Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo Science Advances ·James A. Torchia, Alexander H. Tavares, Laura Stentoft Carstensen, Da‐Yuan Chen, Jessie Huang, Tianshu Xiao, Sonia Mukherjee, Patrick M. Reeves, Hua Tu, Ann E. Sluder, Bing Chen, Darrell N. Kotton, Richard A. Bowen, Mohsan Saeed, Mark C. Poznansky, Gordon J. Freeman	2022	14
11	Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium JCI Insight ·Kristine M. Abo, Julio Sainz de Aja, Jonathan Lindstrom-Vautrin, Konstantinos–Dionysios Alysandratos, Alexsia Richards, Carolina García de Alba, Jessie Huang, Olivia T. Hix, Rhiannon B. Werder, Esther Bullitt, Anne Hinds, Isaac Falconer, Carlos Villacorta-Martín, Rudolf Jaenisch, Carla F. Kim, Darrell N. Kotton, Andrew A. Wilson	2022	25
12	SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes Proceedings of the National Academy of Sciences ·Yize Li, David M. Renner, Courtney E. Comar, Jillian N. Whelan, Hanako M. Reyes, Fabian L. Cardenas‐Diaz, Rachel Truitt, Li Tan, Beihua Dong, Konstantinos D. Alysandratos, Jessie Huang, James N. Palmer, Nithin D. Adappa, Michael A. Kohanski, Darrell N. Kotton, Robert H. Silverman, Wenli Yang, Edward E. Morrisey, Noam A. Cohen, Susan R. Weiss	2021	149
13	Derivation of Thyroid Follicular Cells From Pluripotent Stem Cells: Insights From Development and Implications for Regenerative Medicine Frontiers in Endocrinology ·Alberto Posabella, Andrea B. Alber, Hendrik J Undeutsch, Raoul A. Droeser, Anthony N. Hollenberg, Laertis Ikonomou, Darrell N. Kotton	2021	13
14	The in vivo genetic program of murine primordial lung epithelial progenitors Nature Communications ·Laertis Ikonomou, Michael J. Herriges, Sara L. Lewandowski, Robert Marsland, Carlos Villacorta-Martín, Ignacio Caballero, David B. Frank, Reeti Sanghrajka, Keri Dame, Maciej M. Kańduła, Julia Hicks‐Berthet, Matthew Lawton, Constantina Christodoulou, Attila J. Fabian, Eric D. Kolaczyk, Xaralabos Varelas, Edward E. Morrisey, John M. Shannon, Pankaj Mehta, Darrell N. Kotton	2020	40
15	Hidden neural states underlie canary song syntax Nature ·Yarden Cohen, Jun Shen, Dawit Semu, Daniel P. Leman, William A. Liberti, L. Nathan Perkins, Derek C. Liberti, Darrell N. Kotton, Timothy J. Gardner	2020	27
16	Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells Nature Communications ·Aditya Mithal, Amalia Capilla, Dar Heinze, Andrew Berical, Carlos Villacorta-Martín, Marall Vedaie, Anjali Jacob, Kristine M. Abo, Aleksander D. Szymaniak, Megan Peasley, Alexander J. Stuffer, John E. Mahoney, Darrell N. Kotton, Finn Hawkins, Gustavo Mostoslavsky	2020	84
17	Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity The Journal of Immunology ·Emer P. Reeves, Danielle M. Dunlea, Karen McQuillan, Ciara A. O’Dwyer, Tomás P. Carroll, Radka Saldova, Prithvi Reddy Akepati, Mark R. Wormald, Oliver J. McElvaney, Vipatsorn Shutchaidat, Michael Henry, Paula Meleady, Joanne Keenan, Derek C. Liberti, Darrell N. Kotton, Pauline M. Rudd, Andrew A. Wilson, Noel G. McElvaney	2019	17
18	Induced pluripotent stem cells model personalized variations in liver disease resulting from α1‐antitrypsin deficiency Hepatology ·Edgar N. Tafaleng, Souvik Chakraborty, Bing Han, Pamela Hale, Wanquan Wu, Alejandro Soto–Gutiérrez, Carol Feghali‐Bostwick, Andrew A. Wilson, Darrell N. Kotton, Masaki Nagaya, Stephen C. Strom, Jayanta Roy‐Chowdhury, Donna B. Stolz, David H. Perlmutter, Ira J. Fox	2015	62
19	Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes Journal of Clinical Investigation ·Constantina Christodoulou, Tyler A. Longmire, Steven S. Shen, Alice Bourdon, Cesar Sommer, Paul Gadue, Avrum Spira, Valerie Gouon–Evans, George J. Murphy, Gustavo Mostoslavsky, Darrell N. Kotton	2011	39
20	Enhanced Reprogramming and Cardiac Differentiation of Human Keratinocytes Derived from Plucked Hair Follicles, Using a Single Excisable Lentivirus Cellular Reprogramming ·Atara Novak, Ronit Shtrichman, Igal Germanguz, Hanna Segev, Naama Zeevi‐Levin, Bettina Fishman, Yael Mandel, Lili Barad, Hagit Domev, Darrell N. Kotton, Gustavo Mostoslavsky, Ofer Binah, Joseph Itskovitz‐Eldor	2010	56

About Darrell N. Kotton

Darrell N. Kotton is a scholar working on Pulmonary and Respiratory Medicine, Molecular Biology, Genetics, Developmental Biology and Surgery, having authored 143 papers that have together received 8.5k indexed citations. Recurring topics across this work include Neonatal Respiratory Health Research (60 papers), Renal and related cancers (38 papers), Pluripotent Stem Cells Research (29 papers), Tissue Engineering and Regenerative Medicine (20 papers), Congenital heart defects research (14 papers), Congenital Diaphragmatic Hernia Studies (11 papers), Mesenchymal stem cell research (10 papers) and CRISPR and Genetic Engineering (9 papers). The work is most often cited by research in Genetics (992 citations), Pulmonary and Respiratory Medicine (2.7k citations), Surgery (2.9k citations), Molecular Biology (4.3k citations) and Biomaterials (737 citations). Darrell N. Kotton has collaborated with scholars based in United States, Canada and Australia. Frequent co-authors include Edward E. Morrisey, Alan Fine, Gustavo Mostoslavsky, Ross Summer, Laertis Ikonomou, George J. Murphy, Finn Hawkins, Cesar Sommer, Richard C. Mulligan and Attila J. Fabian. Their work appears in journals such as Cell stem cell, Stem Cell Reports, American Journal of Physiology-Lung Cellular and Molecular Physiology, American Journal of Respiratory Cell and Molecular Biology and Journal of Visualized Experiments.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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