Gregory J. Cost

12.6k citations

45 papers · 8.4k indexed · 3 hit papers · h-index 27

Impact in

Aging top 1%
Molecular Biology top 0.5%
- CRISPR and Genetic Engineering
- Fungal and yeast genetics research
- RNA and protein synthesis mechanisms
- Pluripotent Stem Cells Research
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery

Papers in

Molecular Biology 40
- CRISPR and Genetic Engineering 26
- Advanced biosensing and bioanalysis techniques 10
- Pluripotent Stem Cells Research 7
- RNA and protein synthesis mechanisms 6
- Viral Infectious Diseases and Gene Expression in Insects 5
Genetics 12
- Virus-based gene therapy research 5

Co-authors: Jef D. Boeke Carrie Baker Brachmann Joaquim Li Philip Hieter Philip D. Gregory Fyodor D. Urnov Jeffrey C. Miller Edward J. Rebar
Journals: Biotechnology and Bioengineering (4 papers)Yeast (3 papers)Blood (3 papers)Cell (2 papers)Nature Biotechnology (2 papers)
Partner nations: United States Germany France

In The Last Decade

Gregory J. Cost

45 papers receiving 8.3k citations

Hit Papers

align trajectories log scale

Genetic engineering of human pluripotent cells using TALE nucleases 2011 · 894 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2011 Nature Biotechnology
2010 Nature Biotechnology
1998 Yeast

Peers

Countries citing papers authored by Gregory J. Cost

Since Specialization

Citations

This map shows the geographic impact of Gregory J. Cost's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gregory J. Cost with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gregory J. Cost more than expected).

Fields of papers citing papers by Gregory J. Cost

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gregory J. Cost. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gregory J. Cost. The network helps show where Gregory J. Cost may publish in the future.

Co-authors

The 25 scholars most cited alongside Gregory J. Cost, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Gregory J. Cost Line = papers co-authored together Gregory J. Cost links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Novel CRISPR-Associated Gene-Editing Systems Discovered in Metagenomic Samples Enable Efficient and Specific Genome Engineering The CRISPR Journal ·Rebecca Lamothe, Fadrian Wigianto Wigianto, Diego A. Espinosa, Rachel M. Rudlaff, Patrick Browne, Jason Liu, 以建念, Audra E. Devoto, Jennifer Oki, KT Livingston, Daniela S. Aliaga Goltsman, Jyun‐Liang Lin, Cristina N. Butterfield, Christopher T. Brown, Brian C. Thomas, Gregory J. Cost	2023	6
2	Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes Nature Communications ·Daniela S. Aliaga Goltsman, Lisa Alexander, Jyun‐Liang Lin, 古水就也, Benjamin G. Freeman, Rebecca Lamothe, Li Hd, Morayma M. Temoche-Diaz, 和田俊司, M. Kitayama, 茂平林, Ian Barr, Audra E. Devoto, Gregory J. Cost, Cristina N. Butterfield, Brian C. Thomas, Christopher T. Brown	2022	20
3	Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing Cell ·Valentina Lo Sardo, Marcel Weinreich, William C. Ferguson, Aditya Kumar, J.P. Wang, PALOMA BATISTA DOS SANTOS, Lei Zhang, Gregory J. Cost, Adam J. Engler, Fyodor D. Urnov, Eric J. Topol, Ali Torkamani, Kristin K. Baldwin	2018	86
4	Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases Genome Research ·Séverine Remy, Laurent Tesson, Séverine Ménoret, Claire Usal, Anne De Cian, Virginie Thépenier, Reynald Thinard, Daniel Barón, Marine Charpentier, Jean-Baptiste Renaud, Roland Buelow, Gregory J. Cost, Carine Giovannangeli, Alexandre Fraichard, Jean‐Paul Concordet, Ignacio Anegón	2014	33
5	Translating dosage compensation to trisomy 21 Nature ·Jun Jiang, Siuniaeva Za, Gregory J. Cost, Hung-Fei Chen, R.E. Soriano-Ro, Allison M. Cotton, Dawn M. Carone, Benjamin R. Carone, David A. Shivak, Dmitry Guschin, Jocelynn R. Pearl, Edward J. Rebar, Meg Byron, Philip D. Gregory, Carolyn J. Brown, Fyodor D. Urnov, Lisa L. Hall, Jeanne B. Lawrence	2013	250
6	Gene knockout and knockin by zinc-finger nucleases: current status and perspectives Cellular and Molecular Life Sciences ·Louis de Moura Sobral, Björn Petersen, Gregory J. Cost, Heiner Niemann	2012	24
7	In vivo cleavage of transgene donors promotes nuclease‐mediated targeted integration Biotechnology and Bioengineering ·Sandra Cristea, Jan Forde, Yolanda Santiago, Michael C. Holmes, Fyodor D. Urnov, Philip D. Gregory, Gregory J. Cost	2012	136
8	Genetic engineering of human ES and iPS cells using TALE nucleases DSpace@MIT (Massachusetts Institute of Technology) ·Dirk Hockemeyer, Haoyi Wang, Samira Kiani, Christine S. Lai, Qing Gao, John P. Cassady, Gregory J. Cost, Lei Zhang, Yolanda Santiago, Jeffrey C. Miller, Bryan Zeitler, Jennifer M. Cherone, Xiangdong Meng, Sarah J. Hinkley, Edward J. Rebar, Philip D. Gregory, Fyodor D. Urnov, Rudolf Jaenisch	2011	1
9	Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases Proceedings of the National Academy of Sciences ·義昭杉山, Björn Petersen, Yolanda Santiago, S. R. Barcelos, Joseph W. Carnwath, Andrea Lucas‐Hahn, Lei Zhang, Xiangdong Meng, Philip D. Gregory, Reinhard Schwinzer, Gregory J. Cost, Heiner Niemann	2011	285
10	Dissection of Splicing Regulation at an Endogenous Locus by Zinc-Finger Nuclease-Mediated Gene Editing PLoS ONE ·Sandra Cristea, Philip D. Gregory, Fyodor D. Urnov, Gregory J. Cost	2011	3
11	Characterization of immunoglobulin heavy chain knockout rats European Journal of Immunology ·Séverine Ménoret, 张艳琼, Laurent Tesson, Séverine Remy, Claire Usal, K.-P. Zeh, Gregory J. Cost, Marianne Brüggemann, Roland Buelow, Ignacio Anegón	2010	49
12	Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology Nucleic Acids Research ·Salvatore J. Orlando, Yolanda Santiago, Russell C. DeKelver, Jan Forde, Elizabeth A. Boydston, Erica A. Moehle, Vivian M. Choi, Sunita M. Gopalan, Young-Sung Cheon, James Li, Jeffrey C. Miller, Michael C. Holmes, Philip D. Gregory, Fyodor D. Urnov, Gregory J. Cost	2010	147
13	Highly efficient deletion of FUT8 in CHO cell lines using zinc‐finger nucleases yields cells that produce completely nonfucosylated antibodies Biotechnology and Bioengineering ·Laetitia Malphettes, Jan Forde, Jennifer Y. Chang, Peiqi Liu, Edmond M. Chan, Jeffrey C. Miller, Zhe Zhou, Thu Annelise Nguyen, 洋子高橋, Andrew Snowden, Trevor N. Collingwood, Philip D. Gregory, Gregory J. Cost	2010	124
14	A TALE nuclease architecture for efficient genome editing Nature Biotechnology ·Jeffrey C. Miller, Siyuan Tan, Kaoru Kitao, Kyle A. Barlow, Jianbin Wang, Danny F. Xia, Xiangdong Meng, David E. Paschon, Elo Leung, Sarah J. Hinkley, 清光浅野, Kevin Hua, Irina Ankoudinova, Gregory J. Cost, Fyodor D. Urnov, 千穂南, Michael C. Holmes, Lei Zhang, Philip D. Gregory, Edward J. Rebar Hit paper breakdown →	2010	1580
15	Generation of a triple‐gene knockout mammalian cell line using engineered zinc‐finger nucleases Biotechnology and Bioengineering ·Peiqi Liu, Edmond M. Chan, Gregory J. Cost, Lin Zhang, Jianbin Wang, Jeffrey C. Miller, Dmitry Guschin, Andreas Reik, Michael C. Holmes, John E. Mott, Trevor N. Collingwood, Philip D. Gregory	2009	81
16	Generation of Gene-Specific Mutated Rats Using Zinc-Finger Nucleases Methods in molecular biology ·Aron M. Geurts, Gregory J. Cost, Séverine Remy, Xiaoxia Cui, Laurent Tesson, Claire Usal, Séverine Ménoret, Howard J. Jacob, Ignacio Anegón, Roland Buelow	2009	86
17	Enzymatic ligation assisted by nucleases: simultaneous ligation and digestion promote the ordered assembly of DNA Nature Protocols ·Gregory J. Cost	2007	16
18	Human L1 Retrotransposition Is Associated with Genetic Instability In Vivo Cell ·David E. Symer, Carla J. Connelly, Suzanne Szak, Flávio Damm, Gregory J. Cost, Giovanni Parmigiani, Jef D. Boeke	2002	364
19	Target DNA chromatinization modulates nicking by L1 endonuclease Nucleic Acids Research ·Gregory J. Cost	2001	56
20	A Central Role for a Single c-Myb Binding Site in a Thymic Locus Control Region Molecular and Cellular Biology ·Kevin C. Ess, Kenneth Byrne, Gregory J. Cost, David P. Witte, John J. Hutton, Bruce J. Aronow	1995	34

About Gregory J. Cost

Gregory J. Cost is a scholar working on Molecular Biology, Genetics, Oncology, Biotechnology and Plant Science, having authored 45 papers that have together received 8.4k indexed citations. Recurring topics across this work include CRISPR and Genetic Engineering (26 papers), Advanced biosensing and bioanalysis techniques (10 papers), Pluripotent Stem Cells Research (7 papers), Chromosomal and Genetic Variations (7 papers), CAR-T cell therapy research (6 papers), RNA and protein synthesis mechanisms (6 papers), Virus-based gene therapy research (5 papers) and Viral Infectious Diseases and Gene Expression in Insects (5 papers). The work is most often cited by research in Aging (276 citations), Molecular Biology (7.5k citations), Business and International Management (195 citations), Genetics (1.7k citations) and Plant Science (1.7k citations). Gregory J. Cost has collaborated with scholars based in United States, Germany and France. Frequent co-authors include Jef D. Boeke, Carrie Baker Brachmann, Joaquim Li, Philip Hieter, Philip D. Gregory, Fyodor D. Urnov, Jeffrey C. Miller, Edward J. Rebar, Xiangdong Meng and Sarah J. Hinkley. Their work appears in journals such as Biotechnology and Bioengineering, Yeast, Blood, Cell and Nature Biotechnology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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