David A. Guertin

27.5k citations

63 papers · 21.2k indexed · 7 hit papers · h-index 39

Impact in

Biophysics top 0.1%
- Cell Image Analysis Techniques
Aging top 0.5%

Papers in

Biochemistry 9
- Lipid metabolism and biosynthesis 9
Physiology 27
- Adipose Tissue and Metabolism 27

Co-authors: David M. Sabatini Siraj M. Ali Dos D. Sarbassov Joan Sánchez-Gurmaches Jason Moffat Anne E. Carpenter Thouis R. Jones Robert A. Lindquist
Journals: Cell Reports (5 papers)Nature Communications (4 papers)Molecular Metabolism (3 papers)Cell Metabolism (2 papers)Science (2 papers)
Partner nations: United States Australia South Korea

In The Last Decade

David A. Guertin

61 papers receiving 20.9k citations

Hit Papers

7 papers align trajectories log scale

Acetyl-CoA metabolism in cancer 2023 · 161 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2023 Nature reviews. Cancer
2011 Cell
2007 Cancer Cell
2006 Genome biology
2006 Developmental Cell
2005 Science
2004 Current Biology

Peers

Countries citing papers authored by David A. Guertin

Since Specialization

Citations

This map shows the geographic impact of David A. Guertin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David A. Guertin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David A. Guertin more than expected).

Fields of papers citing papers by David A. Guertin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David A. Guertin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David A. Guertin. The network helps show where David A. Guertin may publish in the future.

Co-authors

The 25 scholars most cited alongside David A. Guertin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David A. Guertin Line = papers co-authored together David A. Guertin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation Genes & Development ·Rayna Y. Magesh, Arshia N. Kaur, Faith Keller, Abdulrazak Frederick, Tenzin Tseyang, John D. Haley, Alejandra M Rivera-Nieves, Anthony C. Liang, David A. Guertin, Jessica B. Spinelli, Stephen J. Elledge, Emma V. Watson	2025	0
2	Functional genomic screens with death rate analyses reveal mechanisms of drug action Nature Chemical Biology ·Megan E. Honeywell, Marie S. Isidor, Nicholas W. Harper, Rachel E. Fontana, Gavin A Birdsall, Peter Cruz‐Gordillo, Sydney A Porto, Madison Jerome, Cameron Fraser, Kristopher A. Sarosiek, David A. Guertin, Jessica B. Spinelli, Michael J. Lee	2024	3
3	Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis Nature Metabolism ·Grace Park, John D. Haley, Johnny Le, Su Myung Jung, Timothy P. Fitzgibbons, Ekaterina Korobkina, Huawei Li, Shelagh M. Fluharty, Qingbo Chen, Jessica B. Spinelli, Chinmay M. Trivedi, Cholsoon Jang, David A. Guertin	2023	28
4	A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis Nature Communications ·Qingbo Chen, Lei Huang, Dongning Pan, Kai Hu, Rui Li, Randall H. Friedline, Jason K. Kim, Lihua Julie Zhu, David A. Guertin, Yong‐Xu Wang	2022	21
5	In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate Cell Reports ·Su Myung Jung, Will Doxsey, Johnny Le, John D. Haley, Lorena Mazuecos, Amelia K. Luciano, Huawei Li, Cholsoon Jang, David A. Guertin	2021	37
6	Akt Is S-Palmitoylated: A New Layer of Regulation for Akt Frontiers in Cell and Developmental Biology ·Matı́as Blaustein, Estefanía Piegari, Camila Martínez Calejman, Antonella Vila, Analía Amante, María Victoria Manese, Ari Zeida, Laurence Abrami, Mariela Veggetti, David A. Guertin, Gijs R. van den Brink, María M. Corvi, Alejandro Colman‐Lerner	2021	26
7	Proteome and Phosphoproteome Analysis of Brown Adipocytes Reveals That RICTOR Loss Dampens Global Insulin/AKT Signaling Molecular & Cellular Proteomics ·Samuel Entwisle, Camila Martínez Calejman, Anthony S. Valente, Robert Lawrence, Chien‐Min Hung, David A. Guertin, Judit Villén	2020	6
8	De Novo Lipogenesis as a Source of Second Messengers in Adipocytes Current Diabetes Reports ·Wen‐Yu Hsiao, David A. Guertin	2019	23
9	Brown Adipose Tissue Development and Metabolism Handbook of experimental pharmacology ·Su Myung Jung, Joan Sánchez-Gurmaches, David A. Guertin	2018	99
10	The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond Trends in Endocrinology and Metabolism ·Peter L. Lee, Su Myung Jung, David A. Guertin	2017	54
11	T Cell Exit from Quiescence and Differentiation into Th2 Cells Depend on Raptor-mTORC1-Mediated Metabolic Reprogramming Immunity ·Kai Yang, Sharad Shrestha, Hu Zeng, Peer W. F. Karmaus, Geoffrey Neale, Peter Vogel, David A. Guertin, Richard F. Lamb, Hongbo Chi	2013	311
12	Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity Science ·Dudley W. Lamming, Lan Ye, Pekka Katajisto, Marcus D. Goncalves, Maki Saitoh, Deanna M. Stevens, James G. Davis, Adam B. Salmon, Arlan Richardson, Rexford S. Ahima, David A. Guertin, David M. Sabatini, Joseph A. Baur	2012	52
13	PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors Cell Metabolism ·Joan Sánchez-Gurmaches, Chien‐Min Hung, Cynthia A. Sparks, Yuefeng Tang, Huawei Li, David A. Guertin	2012	274
14	mTOR Complex 1 Plays Critical Roles in Hematopoiesis and Pten-Loss-Evoked Leukemogenesis Cell stem cell ·Demetrios Kalaitzidis, Stephen M. Sykes, Zhu Wang, Natalie Punt, Yuefeng Tang, Christine Ragu, Amit Sinha, Steven Lane, Amanda L. Souza, Clary B. Clish, Dimitrios Anastasiou, D. Gary Gilliland, David T. Scadden, David A. Guertin, Scott A. Armstrong	2012	151
15	Postprandial Hepatic Lipid Metabolism Requires Signaling though Akt2 Independent of the Transcription Factors FoxA2, FoxO1 and SREBP1c PubMed Central ·Min Wan, Karla F. Leavens, Danish Saleh, Rachael Easton, David A. Guertin, Timothy R. Peterson, Klaus H. Kaestner, David M. Sabatini, Morris J. Birnbaum	2011	107
16	mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice Cancer Cell ·David A. Guertin, Deanna M. Stevens, Maki Saitoh, Stephanie Kinkel, Katherine Crosby, Joon-Ho Sheen, David J. Mullholland, Mark A. Magnuson, Hong Wu, David M. Sabatini	2009	316
17	Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1 Developmental Cell ·David A. Guertin, Deanna M. Stevens, Carson C. Thoreen, Aurora A. Burds, Nada Y. Kalaany, Jason Moffat, Michael Brown, Kevin Fitzgerald, David M. Sabatini Hit paper breakdown →	2006	1158
18	Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex Science ·Dos D. Sarbassov, David A. Guertin, Siraj M. Ali, David M. Sabatini Hit paper breakdown →	2005	5211
19	7 Growth Control through the mTOR Network Cold Spring Harbor Monograph Archive ·David A. Guertin, Do‐Hyung Kim, David M. Sabatini	2004	3
20	Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton Current Biology ·Dos D. Sarbassov, Siraj M. Ali, Do‐Hyung Kim, David A. Guertin, Robert Latek, Hediye Erdjument‐Bromage, Paul Tempst, David M. Sabatini Hit paper breakdown →	2004	2141

About David A. Guertin

David A. Guertin is a scholar working on Biochemistry, Physiology, Cell Biology, Cancer Research and Molecular Biology, having authored 63 papers that have together received 21.2k indexed citations. Recurring topics across this work include Adipose Tissue and Metabolism (27 papers), PI3K/AKT/mTOR signaling in cancer (17 papers), Adipokines, Inflammation, and Metabolic Diseases (11 papers), Lipid metabolism and biosynthesis (9 papers), Cancer, Hypoxia, and Metabolism (8 papers), Protein Kinase Regulation and GTPase Signaling (8 papers), Muscle metabolism and nutrition (7 papers) and Fungal and yeast genetics research (5 papers). The work is most often cited by research in Biophysics (1.4k citations), Aging (380 citations), Molecular Biology (14.8k citations), Cell Biology (2.7k citations) and Cancer Research (2.2k citations). David A. Guertin has collaborated with scholars based in United States, Australia and South Korea. Frequent co-authors include David M. Sabatini, Siraj M. Ali, Dos D. Sarbassov, Joan Sánchez-Gurmaches, Jason Moffat, Anne E. Carpenter, Thouis R. Jones, Robert A. Lindquist, Michael R. Lamprecht and Joseph Chang. Their work appears in journals such as Cell Reports, Nature Communications, Molecular Metabolism, Cell Metabolism and Science.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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