Klaus H. Kaestner

52.2k citations

389 papers · 36.3k indexed · 7 hit papers · h-index 108

Aging top 0.2%
Genetics top 0.02%
- Diabetes and associated disorders 65
- Genetics and Neurodevelopmental Disorders 46
Molecular Biology top 0.05%
- Epigenetics and DNA Methylation 57
- FOXO transcription factor regulation 49
- Metabolism, Diabetes, and Cancer 42
Surgery top 0.05%
- Pancreatic function and diabetes 170
Hepatology top 0.2%
- Liver physiology and pathology 32
Endocrinology, Diabetes and Metabolism
- Diabetes Management and Research 35

Co-authors: Jonathan Schug Joshua R. Friedman Catherine S. Lee M. Daniel Lane Peter White Walter Knöchel Daniel E. Martínez Nan Gao
Cited by: Aging Genetics Molecular Biology
Journals: Nature (4 papers)Science (2 papers)Cell (5 papers)
Partner nations: United States Germany Israel

In The Last Decade

Klaus H. Kaestner

383 papers receiving 35.9k citations

Hit Papers

7 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2018 Nature
2011 Journal of Clinical Investigation
2009 Science
2009 Nature Reviews Genetics
2001 Science
2000 Genes & Development
1998 Cell

Peers

Countries citing papers authored by Klaus H. Kaestner

Since Specialization

Citations

This map shows the geographic impact of Klaus H. Kaestner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Klaus H. Kaestner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Klaus H. Kaestner more than expected).

Fields of papers citing papers by Klaus H. Kaestner

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Klaus H. Kaestner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Klaus H. Kaestner. The network helps show where Klaus H. Kaestner may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Klaus H. Kaestner, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Klaus H. Kaestner Line = papers co-authored together Klaus H. Kaestner links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1 Nucleic Acids Research ·Riham Smoom,Catherine Lee May,Dan Lichtental,Kamil Bar-Ness,Roberto Rangel,Johad Khoury,Daphna Nachmani,Dana Avrahami,Farida Ahangari,Emmanuel Skordalakes,Naftali Kaminski,Klaus H. Kaestner,Yehuda Tzfati	2025	1
2	The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation Developmental Cell ·Avital Swisa,Julia E. Kieckhaefer,Scott G. Daniel,Hilana El‐Mekkoussi,Hannah M. Kolev,Mark Tigue,Chunsheng Jin,Charles‐Antoine Assenmacher,Lenka Dohnalová,Christoph A. Thaiss,Niclas G. Karlsson,Kyle Bittinger,Klaus H. Kaestner	2024	3
3	Telomouse—a mouse model with human-length telomeres generated by a single amino acid change in RTEL1 Nature Communications ·Riham Smoom,Catherine Lee May,Vivian Ortiz,Mark Tigue,Hannah M. Kolev,Melissa Rowe,Yitzhak Reizel,Ashleigh Morgan,Nachshon Egyes,Dan Lichtental,Emmanuel Skordalakes,Klaus H. Kaestner,Yehuda Tzfati	2023	15
4	Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry Cell Reports ·Minghui Wu,Michelle Y. Y. Lee,Varun Bahl,Daniel Traum,Jonathan Schug,Irina Kusmartseva,Mark A. Atkinson,Guanjie Fan,Klaus H. Kaestner	2021	39
5	Biphasic dynamics of beta cell mass in a mouse model of congenital hyperinsulinism: implications for type 2 diabetes Diabetologia ·Sharona Tornovsky-Babeay,Noa Weinberg-Corem,Rachel Ben‐Haroush Schyr,Dana Avrahami,Judith Lavi,Eseye Feleke,Klaus H. Kaestner,Yuval Dor,Benjamin Gläser	2021	16
6	A FoxL1-CreERT-2A-tdTomato Mouse Labels Subepithelial Telocytes Cellular and Molecular Gastroenterology and Hepatology ·H.M. Kolev,Ye F. Tian,Melissa S. Kim,N. Adrian Leu,Stephanie Adams‐Tzivelekidis,Christopher J. Lengner,N Li,Klaus H. Kaestner	2021	6
7	NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP) Diabetes ·Klaus H. Kaestner,Alvin C. Powers,Ali Naji,Mark A. Atkinson	2019	96
8	Pax6 regulation of Sox9 in the mouse retinal pigmented epithelium controls its timely differentiation and choroid vasculature development Development ·Yamit Cohen‐Tayar,Hadar Cohen,Yulia Mitiagin,Zohar Abravanel,Carmit Levy,Masha Idelson,Benjamin Reubinoff,Shalev Itzkovitz,S. Raviv,Klaus H. Kaestner,Pablo Blinder,Ran Elkon,Ruth Ashery‐Padan	2018	17
9	Sleeve Gastrectomy Improves Glycemia Independent of Weight Loss by Restoring Hepatic Insulin Sensitivity Diabetes ·Samir Abu‐Gazala,E. Philip Horwitz,Rachel Ben‐Haroush Schyr,Aya Bardugo,Hadar Israeli,Ayat Hija,Jonathan Schug,Soona Shin,Yuval Dor,Klaus H. Kaestner,Danny Ben‐Zvi	2018	40
10	β‐Cells are not uniform after all—Novel insights into molecular heterogeneity of insulin‐secreting cells Diabetes Obesity and Metabolism ·Dana Avrahami,Yue J. Wang,Agnes Klochendler,Yuval Dor,Benjamin Gläser,Klaus H. Kaestner	2017	21
11	DNA Hypomethylation Contributes to Genomic Instability and Intestinal Cancer Initiation Cancer Prevention Research ·Karyn L. Sheaffer,Ellen N. Elliott,Klaus H. Kaestner	2016	93
12	The RNA Polymerase III Subunit Polr3b Is Required for the Maintenance of Small Intestinal Crypts in Mice Cellular and Molecular Gastroenterology and Hepatology ·Julia E. Kieckhaefer,Sabina Lukovac,Diana Z. Ye,Dolim Lee,Danielle J. Beetler,Michael Pack,Klaus H. Kaestner	2016	9
13	Foxl1-Expressing Mesenchymal Cells Constitute the Intestinal Stem Cell Niche Cellular and Molecular Gastroenterology and Hepatology ·Reina Aoki,Michal Shoshkes-Carmel,Nan Gao,Soona Shin,Catherine Lee May,Maria L. Golson,Adam M. Zahm,Michael Ray,Caroline L. Wiser,Christopher V.E. Wright,Klaus H. Kaestner	2015	199
14	KLF Family Members Regulate Intrinsic Axon Regeneration Abilitybreakdown → Science ·Darcie L. Moore,Murray G. Blackmore,Ying Hu,Klaus H. Kaestner,John L. Bixby,Vance Lemmon,Jeffrey L. Goldberg	2009	541
15	Haploinsufficiency of Kruppel-Like Factor 4 Promotes Adenomatous Polyposis Coli–Dependent Intestinal Tumorigenesis Cancer Research ·Amr M. Ghaleb,Beth B. McConnell,Mandayam O. Nandan,Jonathan P. Katz,Klaus H. Kaestner,Vincent W. Yang	2007	86
16	The MODY1 gene HNF-4α regulates selected genes involved in insulin secretion Journal of Clinical Investigation ·Rana K. Gupta,Marko Z. Vatamaniuk,Catherine S. Lee,Reed C. Flaschen,James Fulmer,Franz M. Matschinsky,Stephen A. Duncan,Klaus H. Kaestner	2005	159
17	The MODY1 gene HNF-4α regulates selected genes involved in insulin secretion Journal of Clinical Investigation ·Rana K. Gupta,Marko Z. Vatamaniuk,Catherine S. Lee,Reed C. Flaschen,James Fulmer,Franz M. Matschinsky,Stephen A. Duncan,Klaus H. Kaestner	2005	174
18	Foxa2 is required for transition to air breathing at birth Proceedings of the National Academy of Sciences ·Huajing Wan,Yan Xu,Machiko Ikegami,Mildred T. Stahlman,Klaus H. Kaestner,Siew‐Lan Ang,Jeffrey A. Whitsett	2004	107
19	Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)breakdown → Science ·Han Cho,James Mu,Jason K. Kim,Joanne L. Thorvaldsen,Qingwei Chu,E. Bryan Crenshaw,Klaus H. Kaestner,Marisa S. Bartolomei,Gerald I. Shulman,Morris J. Birnbaum	2001	1512
20	Ron-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses Journal of Clinical Investigation ·Susan E. Waltz,Laura Eaton,Kenya Toney‐Earley,Karla A. Hess,Belinda E. Peace,Jeffrey R. Ihlendorf,Minghai Wang,Klaus H. Kaestner,Sandra J. Friezner Degen	2001	5

About Klaus H. Kaestner

Klaus H. Kaestner is a scholar working on Genetics, Surgery and Hepatology, having authored 389 papers that have together received 36.3k indexed citations. Recurring topics across this work include Pancreatic function and diabetes (170 papers), Diabetes and associated disorders (65 papers), Epigenetics and DNA Methylation (57 papers), FOXO transcription factor regulation (49 papers), Genetics and Neurodevelopmental Disorders (46 papers), Metabolism, Diabetes, and Cancer (42 papers), Diabetes Management and Research (35 papers) and Liver physiology and pathology (32 papers). The work is most often cited by research in Aging (637 citations), Genetics (9.4k citations) and Molecular Biology (22.4k citations). Klaus H. Kaestner has collaborated with scholars based in United States, Germany and Israel. Frequent co-authors include Jonathan Schug, Joshua R. Friedman, Catherine S. Lee, M. Daniel Lane, Peter White, Walter Knöchel, Daniel E. Martínez, Nan Gao, Geetu Tuteja and Günther Schütz. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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