Roberto Zoncu

27.0k total citations · 15 hit papers
71 papers, 20.2k citations indexed

About

Roberto Zoncu is a scholar working on Cell Biology, Molecular Biology and Epidemiology. According to data from OpenAlex, Roberto Zoncu has authored 71 papers receiving a total of 20.2k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Cell Biology, 36 papers in Molecular Biology and 22 papers in Epidemiology. Recurrent topics in Roberto Zoncu's work include Cellular transport and secretion (34 papers), Autophagy in Disease and Therapy (22 papers) and Calcium signaling and nucleotide metabolism (16 papers). Roberto Zoncu is often cited by papers focused on Cellular transport and secretion (34 papers), Autophagy in Disease and Therapy (22 papers) and Calcium signaling and nucleotide metabolism (16 papers). Roberto Zoncu collaborates with scholars based in United States, Spain and Italy. Roberto Zoncu's co-authors include David M. Sabatini, Alejo Efeyan, Liron Bar‐Peled, Yasemin Sancak, Rushika M. Perera, Rosalie Lawrence, Daniel K. Nomura, Andrew L. Markhard, Shigeyuki Nada and James A. Olzmann and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Roberto Zoncu

70 papers receiving 20.0k citations

Hit Papers

mTOR: from growth signal integration to cancer, diabetes ... 2002 2026 2010 2018 2010 2019 2010 2012 2011 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. mTOR: from growth signal integration to cancer, diabetes and ageing
    2010 3.2k citations Roberto Zoncu, Alejo Efeyan et al. Nature Reviews Molecular Cell Biology profile →
  2. The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
    2019 2.6k citations Roberto Zoncu, Daniel K. Nomura et al. Nature profile →
  3. Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
    2010 1.9k citations Yasemin Sancak, Liron Bar‐Peled et al. profile →
  4. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
    2012 1.5k citations Roberto Zoncu, David M. Sabatini et al. profile →
  5. mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H + -ATPase
    2011 1.3k citations Roberto Zoncu, Liron Bar‐Peled et al. Science profile →
  6. Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1
    2012 714 citations Liron Bar‐Peled, Roberto Zoncu et al. profile →
  7. The lysosome as a cellular centre for signalling, metabolism and quality control
    2018 647 citations Rosalie Lawrence, Roberto Zoncu profile →
  8. Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
    2015 618 citations Shuyu Wang, Zhi-Yang Tsun et al. profile →
  9. Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
    2015 615 citations Rushika M. Perera, Svetlana Stoykova et al. Nature profile →
  10. Origin of GABAergic neurons in the human neocortex
    2002 521 citations Krešimir Letinić, Roberto Zoncu et al. Nature profile →
  11. The Lysosome as a Regulatory Hub
    2016 446 citations Rushika M. Perera, Roberto Zoncu profile →
  12. DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy
    2017 438 citations Sharon M. Louie, Roberto Zoncu et al. Developmental Cell profile →
  13. The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1
    2013 421 citations Zhi-Yang Tsun, Liron Bar‐Peled et al. Molecular Cell profile →
  14. Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
    2017 394 citations Brian M. Castellano, Ashley Thelen et al. Science profile →
  15. The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease
    2023 101 citations Roberta Peruzzo, Roberto Zoncu et al. Nature Reviews Molecular Cell Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Roberto Zoncu United States 45 12.6k 4.8k 4.8k 2.9k 2.7k 71 20.2k
Jayanta Debnath United States 58 9.3k 0.7× 3.1k 0.6× 7.5k 1.5× 2.7k 0.9× 1.4k 0.5× 106 17.1k
Ken Inoki United States 56 12.9k 1.0× 2.4k 0.5× 3.4k 0.7× 1.8k 0.6× 3.0k 1.1× 92 17.9k
Brendan D. Manning United States 62 22.0k 1.7× 3.5k 0.7× 3.6k 0.7× 4.9k 1.7× 4.5k 1.7× 118 30.9k
Tohru Natsume Japan 58 11.3k 0.9× 3.9k 0.8× 5.1k 1.1× 1.2k 0.4× 1.0k 0.4× 198 16.3k
Francesco Cecconi Italy 57 10.2k 0.8× 2.3k 0.5× 6.5k 1.3× 1.6k 0.6× 2.0k 0.8× 176 17.3k
Richard Kolesnick United States 75 18.2k 1.4× 3.4k 0.7× 1.2k 0.3× 2.1k 0.7× 3.6k 1.3× 149 23.8k
Lina M. Obeid United States 94 26.4k 2.1× 7.4k 1.5× 2.4k 0.5× 1.5k 0.5× 5.3k 2.0× 291 30.5k
Adi Kimchi Israel 67 13.0k 1.0× 2.8k 0.6× 6.9k 1.4× 2.1k 0.7× 1.0k 0.4× 156 20.0k
Gian María Fimia Italy 55 6.5k 0.5× 2.7k 0.6× 5.6k 1.2× 963 0.3× 945 0.4× 156 14.7k
Jerold Chun United States 99 23.9k 1.9× 6.7k 1.4× 1.1k 0.2× 1.5k 0.5× 4.2k 1.6× 334 31.6k

Countries citing papers authored by Roberto Zoncu

Since Specialization
Citations

This map shows the geographic impact of Roberto Zoncu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roberto Zoncu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roberto Zoncu more than expected).

Fields of papers citing papers by Roberto Zoncu

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roberto Zoncu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roberto Zoncu. The network helps show where Roberto Zoncu may publish in the future.

Co-authorship network of co-authors of Roberto Zoncu

This figure shows the co-authorship network connecting the top 25 collaborators of Roberto Zoncu. A scholar is included among the top collaborators of Roberto Zoncu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Roberto Zoncu. Roberto Zoncu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Rademaker, Gilles, David J. Anderson, Zuopeng Zhang, et al.. (2025). Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins. Science. 387(6741). eadq8331–eadq8331. 3 indexed citations
2.
Peruzzo, Roberta, et al.. (2023). Author Correction: The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease. Nature Reviews Molecular Cell Biology. 24(12). 934–934. 8 indexed citations
3.
Shin, Hijai R., Lei Wang, Yusuke Sugasawa, et al.. (2022). Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1. Science. 377(6612). 1290–1298. 62 indexed citations
4.
Shin, Hijai R. & Roberto Zoncu. (2020). The Lysosome at the Intersection of Cellular Growth and Destruction. Developmental Cell. 54(2). 226–238. 78 indexed citations
5.
Castellano, Brian M., Ashley Thelen, Ofer Moldavski, et al.. (2017). Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex. Science. 355(6331). 1306–1311. 394 indexed citations breakdown →
6.
Su, Ming-Yuan, Kyle L. Morris, Dojin Kim, et al.. (2017). Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex. Molecular Cell. 68(5). 835–846.e3. 69 indexed citations
7.
Tsun, Zhi-Yang, Rachel L. Wolfson, Kuang Shen, et al.. (2015). Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. Science. 347(6218). 188–194. 17 indexed citations
8.
Katajisto, Pekka, Christine L. Chaffer, Nalle Pentinmikko, et al.. (2015). Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness. Science. 348(6232). 340–343. 390 indexed citations
9.
Wheeler, Douglas B., Roberto Zoncu, David E. Root, David M. Sabatini, & Charles L. Sawyers. (2015). Identification of an oncogenic RAB protein. Science. 350(6257). 211–217. 95 indexed citations
10.
Katajisto, Pekka, Christine L. Chaffer, Nalle Pentinmikko, et al.. (2015). Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness. PMC. 1 indexed citations
11.
Tooze, Sharon A. & Roberto Zoncu. (2015). Control of cellular homeostasis: organelles take the pilot's seat. Molecular Biology of the Cell. 26(6). 1009–1010. 3 indexed citations
12.
Perera, Rushika M., Svetlana Stoykova, Brandon Nicolay, et al.. (2015). Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism. Nature. 524(7565). 361–365. 615 indexed citations breakdown →
13.
Efeyan, Alejo, Roberto Zoncu, & David M. Sabatini. (2012). Amino acids and mTORC1: from lysosomes to disease. Trends in Molecular Medicine. 18(9). 524–533. 332 indexed citations
14.
Zoncu, Roberto, Liron Bar‐Peled, Alejo Efeyan, et al.. (2011). mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H + -ATPase. Science. 334(6056). 678–683. 1251 indexed citations breakdown →
15.
Zoncu, Roberto, Liron Bar‐Peled, Alejo Efeyan, et al.. (2011). mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase. DSpace@MIT (Massachusetts Institute of Technology). 20 indexed citations
16.
Nakatsu, Fubito, Rushika M. Perera, Louise Lucast, et al.. (2010). The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics. The Journal of Cell Biology. 190(3). 307–315. 91 indexed citations
17.
Díaz, María Elena, Guillermo Ayala, Teresa León, Roberto Zoncu, & Derek Toomre. (2008). Analyzing Protein-Protein Spatial-Temporal Dependencies from Image Sequences Using Fuzzy Temporal Random Sets. Journal of Computational Biology. 15(9). 1221–1236. 3 indexed citations
18.
Perera, Rushika M., Roberto Zoncu, Louise Lucast, Pietro De Camilli, & Derek Toomre. (2006). Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Proceedings of the National Academy of Sciences. 103(51). 19332–19337. 129 indexed citations
19.
Paolo, Gilbert Di, Lorenzo Pellegrini, Krešimir Letinić, et al.. (2002). Recruitment and regulation of phosphatidylinositol phosphate kinase type 1γ by the FERM domain of talin. Nature. 420(6911). 85–89. 386 indexed citations
20.
Cremisi, Federico, et al.. (2000). PC3 overexpression affects the pattern of cell division of rat cortical precursors. European Journal of Neuroscience. 12(1). 520–520. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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