Walter Kölch

34.5k citations

298 papers · 25.5k indexed · 7 hit papers · h-index 81

Impact in

Molecular Biology top 0.1%
- Melanoma and MAPK Pathways
- Protein Kinase Regulation and GTPase Signaling
- Gene Regulatory Network Analysis
- PI3K/AKT/mTOR signaling in cancer
- Cell death mechanisms and regulation
Cell Biology top 0.1%
- Hippo pathway signaling and YAP/TAZ

Papers in

Molecular Biology 248
- Melanoma and MAPK Pathways 100
- Protein Kinase Regulation and GTPase Signaling 80
- Gene Regulatory Network Analysis 28
- Bioinformatics and Genomic Networks 26
Cell Biology 54
- Hippo pathway signaling and YAP/TAZ 26
- Cellular Mechanics and Interactions 20

Co-authors: Amardeep S. Dhillon Harald Mischak Oliver Rath Suzanne Hagan Boris Ν. Kholodenko Jens Rauch Eric O’Neill Gisela Heidecker
Journals: Molecular and Cellular Biology (17 papers)Journal of Biological Chemistry (10 papers)Cancer Research (10 papers)Cellular Signalling (9 papers)Oncogene (8 papers)
Partner nations: Ireland United Kingdom United States

In The Last Decade

Walter Kölch

293 papers receiving 25.1k citations

Hit Papers

7 papers align trajectories log scale

Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity 2020 · 576 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 International Journal of Molecular Sciences
2007 Oncogene
2005 Nature Reviews Molecular Cell Biology
2000 Biochemical Journal
1999 Nature
1993 Nature
1993 Journal of Biological Chemistry

Peers

Countries citing papers authored by Walter Kölch

Since Specialization

Citations

This map shows the geographic impact of Walter Kölch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Walter Kölch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Walter Kölch more than expected).

Fields of papers citing papers by Walter Kölch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Walter Kölch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Walter Kölch. The network helps show where Walter Kölch may publish in the future.

Co-authors

The 25 scholars most cited alongside Walter Kölch, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Walter Kölch Line = papers co-authored together Walter Kölch links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	BTLA and PD-1 signals attenuate TCR-mediated transcriptomic changes iScience ·W. Sachs, Judith Leitner, 寛井田, Petra Waidhofer‐Söllner, Walter Kölch, Vadim Zhernovkov, Peter Steinberger	2024	3
2	Cell State Transition Models Stratify Breast Cancer Cell Phenotypes and Reveal New Therapeutic Targets Cancers ·Oleksii S. Rukhlenko, Amir Hassanian, Алексей Николаевич Клименюк, S.E.R. Langberg, Ketan Thombare, M González-Pérez, Walter Kölch, Boris Ν. Kholodenko	2024	3
3	Small Gene Networks Delineate Immune Cell States and Characterize Immunotherapy Response in Melanoma Cancer Immunology Research ·寛井田, Neng Rian Nur’aeni, Aun-Kee Chong, Kestrel Wright, Simon J. Dovedi, Viia Valge-Archer, Amit Grover, Robert W. Wilkinson, Yolanda Carbajal Suárez, Claus Bendtsen, Ian P. Barrett, Donal J. Brennan, Walter Kölch, Vadim Zhernovkov	2023	2
4	Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma Life Science Alliance ·David Romano, Lucia García-Gutiérrez, Virginia Paine, David J. Duffy, Keith T. Flaherty, Dennie T. Frederick, Walter Kölch, David Matallanas	2022	5
5	B-cell-derived transforming growth factor-β may drive the activation of inflammatory macrophages and contribute to scarring in hidradenitis suppurativa British Journal of Dermatology ·Conor M. Smith, Róisín Hambly, S. Gatault, Kestrel Wright, 嘉夫亀田, 田浩浩, ak Ugi. Lucy, 達三本林, Shivashini Kirthi, Rosalind Hughes, Jean M. Fletcher, Walter Kölch, Brian Kirby	2022	6
6	Accurate prediction of kinase-substrate networks using knowledge graphs PLoS Computational Biology ·Vít Nováček, Sathya Narayanan, David Matallanas, Alfonso Blanco, Nikolay K. Baulin, Lena Kjällman, Luca Costabello, Longcong Dong, 宏俊越前, W. Krause, Sameh K. Mohamed, Pierre-Yves Vandenbussche, Colm J. Ryan, Walter Kölch, Dirk Fey	2020	17
7	Protein–protein interactions generate hidden feedback and feed-forward loops to trigger bistable switches, oscillations and biphasic dose–responses Molecular BioSystems ·Thawfeek Varusai, Walter Kölch, Boris Ν. Kholodenko, Lan K. Nguyen	2015	26
8	GSK3 Inhibitors Regulate MYCN mRNA Levels and Reduce Neuroblastoma Cell Viability through Multiple Mechanisms, Including p53 and Wnt Signaling Molecular Cancer Therapeutics ·David J. Duffy, Aleksandar Krstić, Thomas Schwarzl, Desmond G. Higgins, Walter Kölch	2013	71
9	Control of the G-protein cascade dynamics by GDP dissociation inhibitors Molecular BioSystems ·Elena Nikonova, M. A. Tsyganov, Walter Kölch, Dirk Fey, Boris Ν. Kholodenko	2013	13
10	The topology design principles that determine the spatiotemporal dynamics of G-protein cascades Molecular BioSystems ·M. A. Tsyganov, Walter Kölch, Boris Ν. Kholodenko	2012	29
11	Mammalian protein expression noise: scaling principles and the implications for knockdown experiments Molecular BioSystems ·Marc R. Birtwistle, Alex von Kriegsheim, Maciej Dobrzyński, Boris Ν. Kholodenko, Walter Kölch	2012	8
12	c-Myc Regulates RNA Splicing of the A-Raf Kinase and Its Activation of the ERK Pathway Cancer Research ·Jens Rauch, Kim Moran‐Jones, Valérie Albrecht, Thomas Schwarzl, Keith D. Hunter, Olivier Gires, Walter Kölch	2011	51
13	Raf Kinase Inhibitor Protein RKIP Enhances Signaling by Glycogen Synthase Kinase-3β Cancer Research ·Fahd Al‐Mulla, Milad S. Bitar, May Al‐Maghrebi, A. Behbehani, Waleed Al-Ali, Oliver Rath, Brendan Doyle, Samyeung Shin, Andrew R. Pitt, Walter Kölch	2011	96
14	Proapoptotic Kinase MST2 Coordinates Signaling Crosstalk between RASSF1A, Raf-1, and Akt Cancer Research ·David Romano, David Matallanas, Gregory Weitsman, Christian Preisinger, Tony Ng, Walter Kölch	2010	81
15	Heterogeneous Nuclear Ribonucleoprotein H Blocks MST2-Mediated Apoptosis in Cancer Cells by Regulating a-raf Transcription Cancer Research ·Jens Rauch, Eric O’Neill, Brigitte Mack, Christoph Matthias, Markus Münz, Walter Kölch, Olivier Gires	2010	65
16	Functional Roles of Multiple Feedback Loops in Extracellular Signal-Regulated Kinase and Wnt Signaling Pathways That Regulate Epithelial-Mesenchymal Transition Cancer Research ·Sung‐Young Shin, Oliver Rath, Armin Zebisch, Sang‐Mok Choo, Walter Kölch, Kwang‐Hyun Cho	2010	121
17	RAFkinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility Molecular BioSystems ·Fahd Al‐Mulla, Milad S. Bitar, Zainab J. Taqi, Oliver Rath, Walter Kölch	2010	39
18	Role of the Kinase MST2 in Suppression of Apoptosis by the Proto-Oncogene Product Raf-1 Science ·Eric O’Neill, Linda Rushworth, Manuela Baccarini, Walter Kölch	2004	243
19	Negative Regulation of Raf-1 by Phosphorylation of Serine 621 Molecular and Cellular Biology ·Harald Mischak, Thomas Seitz, Petra Janosch, Manfred Eulitz, G. Mannoj Rajkumar, L A Gogoladze, E. Jünger, Walter Kölch	1996	176
20	Probing structure and function of the raf protein kinase domain with monoclonal antibodies. PubMed ·Walter Kölch, Eva M. Weissinger, Harald Mischak, Jakob Troppmair, Chen Chen, Patricia A. Lloyd, Gisela Heidecker, Rapp Ur	1990	35

About Walter Kölch

Walter Kölch is a scholar working on Molecular Biology, Cell Biology, Computational Theory and Mathematics, Cancer Research and Pathology and Forensic Medicine, having authored 298 papers that have together received 25.5k indexed citations. Recurring topics across this work include Melanoma and MAPK Pathways (100 papers), Protein Kinase Regulation and GTPase Signaling (80 papers), Computational Drug Discovery Methods (34 papers), Gene Regulatory Network Analysis (28 papers), Bioinformatics and Genomic Networks (26 papers), Hippo pathway signaling and YAP/TAZ (26 papers), Cancer Mechanisms and Therapy (24 papers) and Cellular Mechanics and Interactions (20 papers). The work is most often cited by research in Molecular Biology (18.9k citations), Cell Biology (3.7k citations), Cancer Research (2.7k citations), Oncology (4.5k citations) and Pathology and Forensic Medicine (2.6k citations). Walter Kölch has collaborated with scholars based in Ireland, United Kingdom and United States. Frequent co-authors include Amardeep S. Dhillon, Harald Mischak, Oliver Rath, Suzanne Hagan, Boris Ν. Kholodenko, Jens Rauch, Eric O’Neill, Gisela Heidecker, Ulf R. Rapp and Andrew R. Pitt. Their work appears in journals such as Molecular and Cellular Biology, Journal of Biological Chemistry, Cancer Research, Cellular Signalling and Oncogene.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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