Christopher W. am Ende

3.9k total citations · 2 hit papers
52 papers, 2.7k citations indexed

About

Christopher W. am Ende is a scholar working on Organic Chemistry, Molecular Biology and Pharmaceutical Science. According to data from OpenAlex, Christopher W. am Ende has authored 52 papers receiving a total of 2.7k indexed citations (citations by other indexed papers that have themselves been cited), including 32 papers in Organic Chemistry, 29 papers in Molecular Biology and 12 papers in Pharmaceutical Science. Recurrent topics in Christopher W. am Ende's work include Click Chemistry and Applications (21 papers), Chemical Synthesis and Analysis (18 papers) and Fluorine in Organic Chemistry (10 papers). Christopher W. am Ende is often cited by papers focused on Click Chemistry and Applications (21 papers), Chemical Synthesis and Analysis (18 papers) and Fluorine in Organic Chemistry (10 papers). Christopher W. am Ende collaborates with scholars based in United States, United Kingdom and Germany. Christopher W. am Ende's co-authors include Joseph M. Fox, Véronique Gouverneur, Natan J. W. Straathof, Jeroen B. I. Sap, Claudio F. Meyer, Andrés A. Trabanco, Douglas S. Johnson, Yinzhi Fang, Peter J. Tonge and Samuel L. Scinto and has published in prestigious journals such as Nature, Journal of the American Chemical Society and Chemical Society Reviews.

In The Last Decade

Christopher W. am Ende

50 papers receiving 2.7k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Bioorthogonal chemistry

2021 389 citations Christopher W. am Ende, John Paul Pezacki et al. profile →
Late-stage difluoromethylation: concepts, developments and perspective

2021 302 citations Jeroen B. I. Sap, Claudio F. Meyer et al. Chemical Society Reviews profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Christopher W. am Ende United States	27	1.7k	1.3k	687	301	224	52	2.7k
Michael A. Poss United States	29	2.2k 1.3×	1.2k 0.9×	179 0.3×	111 0.4×	357 1.6×	81	3.1k
Neil P. Grimster United States	18	2.8k 1.6×	685 0.5×	173 0.3×	94 0.3×	306 1.4×	28	3.3k
Hai‐Bing Zhou China	31	1.4k 0.8×	1.1k 0.9×	113 0.2×	102 0.3×	294 1.3×	128	2.8k
Luke R. Odell Sweden	30	1.5k 0.9×	956 0.7×	116 0.2×	74 0.2×	302 1.3×	102	2.6k
Andrew P. Combs United States	25	2.4k 1.4×	1.7k 1.3×	86 0.1×	72 0.2×	188 0.8×	65	3.9k
William K. Hagmann United States	25	3.2k 1.8×	1.4k 1.1×	2.5k 3.6×	102 0.3×	864 3.9×	78	5.4k
Ekaterina V. Vinogradova United States	27	2.0k 1.1×	1.3k 1.0×	642 0.9×	173 0.6×	449 2.0×	55	3.0k
Mark T. Bilodeau United States	30	3.4k 2.0×	2.0k 1.6×	102 0.1×	125 0.4×	458 2.0×	67	4.6k
Rodolfo Lavilla Spain	31	3.2k 1.8×	1.3k 1.0×	141 0.2×	38 0.1×	232 1.0×	109	4.0k
Matthieu Sollogoub France	39	3.0k 1.7×	2.0k 1.6×	473 0.7×	145 0.5×	427 1.9×	160	4.1k

Countries citing papers authored by Christopher W. am Ende

Since Specialization

Citations

This map shows the geographic impact of Christopher W. am Ende's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher W. am Ende with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher W. am Ende more than expected).

Fields of papers citing papers by Christopher W. am Ende

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher W. am Ende. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher W. am Ende. The network helps show where Christopher W. am Ende may publish in the future.

Co-authorship network of co-authors of Christopher W. am Ende

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher W. am Ende. A scholar is included among the top collaborators of Christopher W. am Ende based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher W. am Ende. Christopher W. am Ende is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Conway, Louis P., Appaso Mahadev Jadhav, Jason K. Dutra, et al.. (2024). Mechanistic differences between linear vs. spirocyclic dialkyldiazirine probes for photoaffinity labeling. Chemical Science. 15(37). 15463–15473.

Xu, Yingrong, et al.. (2023). Thiomethyltetrazines Are Reversible Covalent Cysteine Warheads Whose Dynamic Behavior can be “Switched Off” via Bioorthogonal Chemistry Inside Live Cells. Journal of the American Chemical Society. 145(29). 16069–16080. 27 indexed citations

Lee, Jisun, et al.. (2023). Sulfur(vi) fluorides as tools in biomolecular and medicinal chemistry. Organic & Biomolecular Chemistry. 21(7). 1356–1372. 52 indexed citations

Limberakis, Chris, Roger B. Ruggeri, Matthew Dowling, et al.. (2023). Bioorthogonal Tethering Enhances Drug Fragment Affinity for G Protein-Coupled Receptors in Live Cells. Journal of the American Chemical Society. 145(20). 11173–11184. 9 indexed citations

Sap, Jeroen B. I., Claudio F. Meyer, Joseph Ford, et al.. (2022). [18F]Difluorocarbene for positron emission tomography. Nature. 606(7912). 102–108. 48 indexed citations

Sap, Jeroen B. I., Claudio F. Meyer, Natan J. W. Straathof, et al.. (2021). Late-stage difluoromethylation: concepts, developments and perspective. Chemical Society Reviews. 50(14). 8214–8247. 302 indexed citations breakdown →

Abbasov, Mikail E., Madeline E. Kavanagh, Taka-Aki Ichu, et al.. (2021). A proteome-wide atlas of lysine-reactive chemistry. Nature Chemistry. 13(11). 1081–1092. 156 indexed citations

Dutra, Jason K., Timothy L. Foley, Zhen Huang, et al.. (2021). Fluorophosphonates on‐Demand: A General and Simplified Approach toward Fluorophosphonate Synthesis. ChemBioChem. 22(10). 1769–1774. 5 indexed citations

Mahapatra, Subham, Todd W. Butler, Jason K. Dutra, et al.. (2020). SuFEx Activation with Ca(NTf ₂ ) ₂ : A Unified Strategy to Access Sulfamides, Sulfamates, and Sulfonamides from S(VI) Fluorides. Organic Letters. 22(11). 4389–4394. 113 indexed citations

10.

Sap, Jeroen B. I., Natan J. W. Straathof, Thomas Knauber, et al.. (2020). Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery. Journal of the American Chemical Society. 142(20). 9181–9187. 156 indexed citations

11.

Xie, Longfei, Christopher W. am Ende, Martin Pettersson, et al.. (2019). Synthesis of Pyridopyrazine-1,6-dione γ-Secretase Modulators via Selective 4-Methylimidazole N¹-Buchwald Arylation. The Journal of Organic Chemistry. 84(8). 4921–4925. 3 indexed citations

12.

Mukherjee, Paramita, Rongqiang Liu, Edelweiss Evrard, et al.. (2018). Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides. Organic Letters. 20(3). 812–815. 112 indexed citations

13.

Conrad, Karen S., Daniel Ysselstein, Saskia Heybrock, et al.. (2017). Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies. Nature Communications. 8(1). 1908–1908. 48 indexed citations

14.

Ende, Christopher W. am, Kieran F. Geoghegan, Chuong Nguyen, et al.. (2017). Mapping the Binding Site of BMS-708163 on γ-Secretase with Cleavable Photoprobes. Cell chemical biology. 24(1). 3–8. 36 indexed citations

15.

Zuhl, Andrea M., Charles E. Nolan, Michael A. Brodney, et al.. (2016). Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors. Nature Communications. 7(1). 13042–13042. 59 indexed citations

16.

Murrey, Heather E., Joshua C. Judkins, Christopher W. am Ende, et al.. (2015). Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging. Journal of the American Chemical Society. 137(35). 11461–11475. 153 indexed citations

17.

Pozdnyakov, Nikolay, Heather E. Murrey, Christina J. Crump, et al.. (2013). γ-Secretase Modulator (GSM) Photoaffinity Probes Reveal Distinct Allosteric Binding Sites on Presenilin. Journal of Biological Chemistry. 288(14). 9710–9720. 82 indexed citations

18.

Tran, Tuan P., et al.. (2013). Synthesis of Pyridopyrazine-1,6-diones from 6-Hydroxypicolinic Acids via a One-Pot Coupling/Cyclization Reaction. Organic Letters. 15(3). 642–645. 16 indexed citations

19.

Crump, Christina J., Christopher W. am Ende, T. Eric Ballard, et al.. (2012). Development of clickable active site-directed photoaffinity probes for γ-secretase. Bioorganic & Medicinal Chemistry Letters. 22(8). 2997–3000. 23 indexed citations

20.

Pettersson, Martin, Douglas S. Johnson, Chakrapani Subramanyam, et al.. (2012). Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators. Bioorganic & Medicinal Chemistry Letters. 22(8). 2906–2911. 21 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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