Madeline E. Kavanagh

758 citations

15 papers · 466 indexed · h-index 10

Impact in

Organic Chemistry top 10%
- Click Chemistry and Applications
Pharmacology top 10%
- Pharmacogenetics and Drug Metabolism

Papers in

Pharmacology 7
- Pharmacogenetics and Drug Metabolism 7
Infectious Diseases 8
- Tuberculosis Research and Epidemiology 8

Co-authors: Anthony G. Coyne Chris Abell Michael Kassiou Andrew W. Munro Kirsty J. McLean Benjamin F. Cravatt Munikumar Reddy Doddareddy Matthew M. Hayward
Journals: European Journal of Medicinal Chemistry (2 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)Journal of Medicinal Chemistry (2 papers)Scientific Reports (1 paper)Nature Chemistry (1 paper)
Partner nations: United Kingdom United States Australia

In The Last Decade

Madeline E. Kavanagh

14 papers receiving 458 citations

Peers

Countries citing papers authored by Madeline E. Kavanagh

Since Specialization

Citations

This map shows the geographic impact of Madeline E. Kavanagh's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Madeline E. Kavanagh with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Madeline E. Kavanagh more than expected).

Fields of papers citing papers by Madeline E. Kavanagh

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Madeline E. Kavanagh. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Madeline E. Kavanagh. The network helps show where Madeline E. Kavanagh may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Madeline E. Kavanagh, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Madeline E. Kavanagh Line = papers co-authored together Madeline E. Kavanagh links everyone, so they are left out of the graph.

All Works

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15 of 15 papers shown

#	Work
1	Fragment-Based Development of Small Molecule Inhibitors Targeting Mycobacterium tuberculosis Cholesterol Metabolism Journal of Medicinal Chemistry ·Madeline E. Kavanagh, Kirsty J. McLean, P. Preißler, Yi Guo, M. Snee, Richard B. Tunnicliffe, Kriti Arora, Helena I. Boshoff, Alexander Fanourakis, María José Rebollo-López, Fátima Ortega, Colin Levy, Andrew W. Munro, David Leys, Chris Abell, Anthony G. Coyne	2025	0
2	Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis Chemistry - A European Journal ·V.N. Buzin, M. Snee, Richard B. Tunnicliffe, Madeline E. Kavanagh, Helena I. Boshoff, Cecilia Nwadiuto Amadi, Colin Levy, Andrew W. Munro, Chris Abell, David Leys, Anthony G. Coyne, Kirsty J. McLean	2023	4
3	A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen) European Journal of Medicinal Chemistry ·Martyn Frederickson, Merna Elseragy, Dimitrios Evangelopoulos, Kirsty J. McLean, V.N. Buzin, Richard B. Tunnicliffe, Flora Isabel Ramalho Leite Reis, Madeline E. Kavanagh, Sitthivut Charoensutthivarakul, Richard T. Blankley, Colin Levy, Luiz Pedro S. de Carvalho, David Leys, Andrew W. Munro, Anthony G. Coyne, Chris Abell	2022	5
4	Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine Nature Chemical Biology ·Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, Nilotpal Roy, M O Lima Filho, Landon R. Whitby, 劉民權, M. Horzum, Albert E. Parker, Joel M. Chick, Christie L. Eissler, Sylwia Sobieralska, Shay Simpson, Zhih-Young Lee, Kim Masuda, John R. Teijaro, Gabriel M. Simon, Matthew P. Patricelli, Benjamin F. Cravatt	2022	57
5	A proteome-wide atlas of lysine-reactive chemistry Nature Chemistry ·Mikail E. Abbasov, Madeline E. Kavanagh, Taka-Aki Ichu, Michael R. Lazear, Yongfeng Tao, Vincent M. Crowley, Christopher W. am Ende, Stephan M. Hacker, E Gonzalez-Solares, Melissa M. Dix, Radu M. Suciu, Matthew M. Hayward, Laura L. Kiessling, Benjamin F. Cravatt	2021	156
6	Effect of DMSO on Protein Structure and Interactions Assessed by Collision-Induced Dissociation and Unfolding Analytical Chemistry ·E.A Zuniga, Madeline E. Kavanagh, Kirsty J. McLean, Andrew W. Munro, Dijana Matak‐Vinković, Anthony G. Coyne, Chris Abell	2017	48
7	Fragment Profiling Approach to Inhibitors of the Orphan M. tuberculosis P450 CYP144A1 Biochemistry ·Madeline E. Kavanagh, Акбопе Тонтаевна Ермекбаева, Azedine Zoufir, Kirsty J. McLean, Anthony G. Coyne, Andreas Bender, Andrew W. Munro, Chris Abell	2017	6
8	Structural characterization of CYP144A1 – a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis Scientific Reports ·Акбопе Тонтаевна Ермекбаева, Madeline E. Kavanagh, Max D. Driscoll, Kirsty J. McLean, Douglas B. Young, Teresa Cortes, Dijana Matak‐Vinković, Colin Levy, Stephen E. J. Rigby, David Leys, Chris Abell, Andrew W. Munro	2016	8
9	Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1 Journal of Biological Chemistry ·Акбопе Тонтаевна Ермекбаева, Lê Văn Duyệt, Yinghao Xu, Kirsty J. McLean, Madeline E. Kavanagh, Anthony G. Coyne, Stephen E. J. Rigby, Myles R. Cheesman, Hazel M. Girvan, Colin Levy, T. Staftan, Jens Peter von Kries, Chris Abell, David Leys, Andrew W. Munro	2016	17
10	Spirooxindoles as novel 3D-fragment scaffolds: Synthesis and screening against CYP121 from M. tuberculosis Bioorganic & Medicinal Chemistry Letters ·Holly J. Davis, Madeline E. Kavanagh, E. I. Bakhareva, Chris Abell, Anthony G. Coyne	2016	17
11	Fragment-Based Approaches to the Development ofMycobacterium tuberculosisCYP121 Inhibitors Journal of Medicinal Chemistry ·Madeline E. Kavanagh, Anthony G. Coyne, Kirsty J. McLean, ДЕМИНА А.А. ДЕМИНА А.А., Colin Levy, Leonardo Mariño, Luiz Pedro S. de Carvalho, Daniel Shiu‐Hin Chan, Sean A. Hudson, Sachin Surade, David Leys, Andrew W. Munro, Chris Abell	2016	50
12	Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors ChemMedChem ·Madeline E. Kavanagh, Allyson Walsh, P. Preißler, Anthony G. Coyne, Kirsty J. McLean, Holly J. Davis, Andrew W. Munro, Chris Abell	2016	17
13	Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation European Journal of Medicinal Chemistry ·Lenka Munoz, Madeline E. Kavanagh, 一浩寺島, Benjamin Heng, Nicolas Dzamko, R Ronisz, Munikumar Reddy Doddareddy, Gilles J. Guillemin, Michael Kassiou	2015	29
14	The development of CNS-active LRRK2 inhibitors using property-directed optimisation Bioorganic & Medicinal Chemistry Letters ·Madeline E. Kavanagh, Munikumar Reddy Doddareddy, Michael Kassiou	2013	25
15	Synthesis of Biologically Active Seven-Membered-Ring Heterocycles Synthesis ·Michael Kassiou, Tristan A. Reekie, Madeline E. Kavanagh, Mitchell Longworth	2013	27

About Madeline E. Kavanagh

Madeline E. Kavanagh is a scholar working on Pharmacology, Infectious Diseases, Molecular Biology, Immunology and Allergy and Neurology, having authored 15 papers that have together received 466 indexed citations. Recurring topics across this work include Tuberculosis Research and Epidemiology (8 papers), Pharmacogenetics and Drug Metabolism (7 papers), Biochemical and Molecular Research (4 papers), Chemical Synthesis and Analysis (3 papers), Cancer therapeutics and mechanisms (2 papers), Click Chemistry and Applications (2 papers), Computational Drug Discovery Methods (2 papers) and Parkinson's Disease Mechanisms and Treatments (2 papers). The work is most often cited by research in Organic Chemistry (189 citations), Pharmacology (50 citations), Molecular Biology (302 citations), Infectious Diseases (64 citations) and Oncology (74 citations). Madeline E. Kavanagh has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include Anthony G. Coyne, Chris Abell, Michael Kassiou, Andrew W. Munro, Kirsty J. McLean, Benjamin F. Cravatt, Munikumar Reddy Doddareddy, Matthew M. Hayward, Laura L. Kiessling and Melissa M. Dix. Their work appears in journals such as European Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Scientific Reports and Nature Chemistry.

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