Christopher L. McClendon

3.5k total citations · 1 hit paper
25 papers, 2.7k citations indexed

About

Christopher L. McClendon is a scholar working on Molecular Biology, Materials Chemistry and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Christopher L. McClendon has authored 25 papers receiving a total of 2.7k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 6 papers in Materials Chemistry and 5 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Christopher L. McClendon's work include Protein Structure and Dynamics (19 papers), Protein Kinase Regulation and GTPase Signaling (6 papers) and RNA and protein synthesis mechanisms (6 papers). Christopher L. McClendon is often cited by papers focused on Protein Structure and Dynamics (19 papers), Protein Kinase Regulation and GTPase Signaling (6 papers) and RNA and protein synthesis mechanisms (6 papers). Christopher L. McClendon collaborates with scholars based in United States, Germany and Belgium. Christopher L. McClendon's co-authors include James A. Wells, Matthew P. Jacobson, Susan S. Taylor, Alexandr P. Kornev, Michael K. Gilson, David L. Mobley, Gregory D. Friedland, Gianluigi Veglia, Lalima G. Ahuja and Jack Sadowsky and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Christopher L. McClendon

23 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Reaching for high-hanging fruit in drug discovery at protein–protein interfaces

2007 1.5k citations James A. Wells, Christopher L. McClendon Nature profile →

Peers

Christopher L. McClendon

CTM

RNMI

Paul A. Rejto United States

Suzanne B. Shuker United States

Jeffrey R. Huth United States

Lorenz M. Mayr Switzerland

Alexander L. Breeze United Kingdom

John Karanicolas United States

Daniel K. Treiber United States

M. Sundström Sweden

Paul D. Lyne United States

Djordje Müsil Germany

Paul A. Rejto United States

Christopher L. McClendon

1.7k ×0.8

713 ×1.2

CTM

317 ×0.8

276 ×0.7

155 ×0.5

RNMI

Citations per year, relative to Christopher L. McClendon Christopher L. McClendon (= 1×) peers Paul A. Rejto

Countries citing papers authored by Christopher L. McClendon

Since Specialization

Citations

This map shows the geographic impact of Christopher L. McClendon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher L. McClendon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher L. McClendon more than expected).

Fields of papers citing papers by Christopher L. McClendon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher L. McClendon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher L. McClendon. The network helps show where Christopher L. McClendon may publish in the future.

Co-authorship network of co-authors of Christopher L. McClendon

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher L. McClendon. A scholar is included among the top collaborators of Christopher L. McClendon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher L. McClendon. Christopher L. McClendon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Limberakis, Chris, Roger B. Ruggeri, Matthew Dowling, et al.. (2023). Bioorthogonal Tethering Enhances Drug Fragment Affinity for G Protein-Coupled Receptors in Live Cells. Journal of the American Chemical Society. 145(20). 11173–11184. 9 indexed citations

Baumann, Hannah M., Eric Dybeck, Christopher L. McClendon, et al.. (2023). Broadening the Scope of Binding Free Energy Calculations Using a Separated Topologies Approach. Journal of Chemical Theory and Computation. 19(15). 5058–5076. 23 indexed citations

Boehm, Markus, et al.. (2019). Cosolvent-Enhanced Sampling and Unbiased Identification of Cryptic Pockets Suitable for Structure-Based Drug Design. Journal of Chemical Theory and Computation. 15(5). 3331–3343. 31 indexed citations

Ahuja, Lalima G., Alexandr P. Kornev, Christopher L. McClendon, Gianluigi Veglia, & Susan S. Taylor. (2017). Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer. Proceedings of the National Academy of Sciences. 114(6). E931–E940. 43 indexed citations

Pfleger, Christopher, et al.. (2017). Ensemble- and Rigidity Theory-Based Perturbation Approach To Analyze Dynamic Allostery. Journal of Chemical Theory and Computation. 13(12). 6343–6357. 24 indexed citations

Meharena, Hiruy S., Lalima G. Ahuja, Malik M. Keshwani, et al.. (2016). Decoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein Kinases. PLoS Biology. 14(11). e2000127–e2000127. 31 indexed citations

Meng, Hu, Christopher L. McClendon, Ziwei Dai, et al.. (2015). Discovery of Novel 15-Lipoxygenase Activators To Shift the Human Arachidonic Acid Metabolic Network toward Inflammation Resolution. Journal of Medicinal Chemistry. 59(9). 4202–4209. 44 indexed citations

McClendon, Christopher L., Alexandr P. Kornev, Michael K. Gilson, & Susan S. Taylor. (2014). Dynamic architecture of a protein kinase. Proceedings of the National Academy of Sciences. 111(43). E4623–31. 192 indexed citations

McClendon, Christopher L., et al.. (2014). A New Coarse-Grained Model for E. coli Cytoplasm: Accurate Calculation of the Diffusion Coefficient of Proteins and Observation of Anomalous Diffusion. PLoS ONE. 9(9). e106466–e106466. 30 indexed citations

10.

Srivastava, Atul, Alessandro Cembran, Jonggul Kim, et al.. (2014). Synchronous Opening and Closing Motions Are Essential for cAMP-Dependent Protein Kinase A Signaling. Structure. 22(12). 1735–1743. 56 indexed citations

11.

Rapp, Chaya S., et al.. (2013). Hydrogen Bond Strengths in Phosphorylated and Sulfated Amino Acid Residues. PLoS ONE. 8(3). e57804–e57804. 22 indexed citations

12.

Datta, Debajyoti, Christopher L. McClendon, Matthew P. Jacobson, & James A. Wells. (2013). Substrate and Inhibitor-induced Dimerization and Cooperativity in Caspase-1 but Not Caspase-3. Journal of Biological Chemistry. 288(14). 9971–9981. 44 indexed citations

13.

Wan, Xiaobo, Yue Ma, Christopher L. McClendon, Lily Huang, & Niu Huang. (2013). Ab Initio Modeling and Experimental Assessment of Janus Kinase 2 (JAK2) Kinase-Pseudokinase Complex Structure. PLoS Computational Biology. 9(4). e1003022–e1003022. 9 indexed citations

14.

Rapp, Chaya S., et al.. (2013). The role of tyrosine sulfation in the dimerization of the CXCR4:SDF‐1 complex. Protein Science. 22(8). 1025–1036. 11 indexed citations

15.

McClendon, Christopher L.. (2011). Correlated Motions and Allostery. eScholarship (California Digital Library).

16.

McClendon, Christopher L., Gregory D. Friedland, & Matthew P. Jacobson. (2010). Quantifying Correlations Between Allosteric Sites in Thermodynamic Ensembles. Biophysical Journal. 98(3). 385a–386a. 6 indexed citations

17.

Morcos, Faruck, Santanu Chatterjee, Christopher L. McClendon, et al.. (2010). Modeling Conformational Ensembles of Slow Functional Motions in Pin1-WW. PLoS Computational Biology. 6(12). e1001015–e1001015. 75 indexed citations

18.

McClendon, Christopher L., et al.. (2009). Quantifying Correlations Between Allosteric Sites in Thermodynamic Ensembles. Journal of Chemical Theory and Computation. 5(9). 2486–2502. 192 indexed citations

19.

Wells, James A. & Christopher L. McClendon. (2007). Reaching for high-hanging fruit in drug discovery at protein–protein interfaces. Nature. 450(7172). 1001–1009. 1534 indexed citations breakdown →

20.

McClendon, Christopher L., et al.. (2006). Fidelity of seryl-tRNA synthetase to binding of natural amino acids from HierDock first principles computations. Protein Engineering Design and Selection. 19(5). 195–203. 11 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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