Carmela R. Abraham

13.7k total citations · 4 hit papers
126 papers, 9.1k citations indexed

About

Carmela R. Abraham is a scholar working on Physiology, Molecular Biology and Genetics. According to data from OpenAlex, Carmela R. Abraham has authored 126 papers receiving a total of 9.1k indexed citations (citations by other indexed papers that have themselves been cited), including 66 papers in Physiology, 65 papers in Molecular Biology and 26 papers in Genetics. Recurrent topics in Carmela R. Abraham's work include Alzheimer's disease research and treatments (66 papers), Parathyroid Disorders and Treatments (24 papers) and Genetic Syndromes and Imprinting (22 papers). Carmela R. Abraham is often cited by papers focused on Alzheimer's disease research and treatments (66 papers), Parathyroid Disorders and Treatments (24 papers) and Genetic Syndromes and Imprinting (22 papers). Carmela R. Abraham collaborates with scholars based in United States, United Kingdom and Spain. Carmela R. Abraham's co-authors include Dennis J. Selkoe, Huntington Potter, Lennart Mucke, Eliezer Masliah, Ci-Di Chen, D. J. Selkoe, Daniel A. Kirschner, Douglas L. Rosene, Edward Rockenstein and Yasuo Ihara and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Carmela R. Abraham

125 papers receiving 8.9k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.

1993 861 citations Iain L. Campbell, Carmela R. Abraham et al. Proceedings of the National Academy of Sciences profile →
Immunochemical identification of the serine protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1988 750 citations Carmela R. Abraham et al. profile →
Central nervous system damage produced by expression of the HIV-1 coat protein gpl20 in transgenic mice

1994 574 citations Eliezer Masliah, Edward Rockenstein et al. profile →
X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation.

1986 458 citations Daniel A. Kirschner, Carmela R. Abraham et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Carmela R. Abraham United States	48	4.1k	3.7k	1.7k	1.4k	1.3k	126	9.1k
Efrat Levy United States	45	3.9k 1.0×	3.8k 1.0×	1.1k 0.6×	872 0.6×	373 0.3×	105	7.5k
Kevin R. Lynch United States	71	2.5k 0.6×	10.7k 2.9×	964 0.6×	2.2k 1.6×	727 0.6×	202	16.0k
Asok Kumar United States	36	3.7k 0.9×	2.8k 0.8×	807 0.5×	945 0.7×	226 0.2×	73	7.5k
Keiichi Higuchi Japan	42	2.8k 0.7×	4.0k 1.1×	686 0.4×	417 0.3×	616 0.5×	181	6.6k
Paul M. Mathews United States	53	7.5k 1.8×	4.5k 1.2×	2.4k 1.4×	2.0k 1.5×	352 0.3×	106	11.3k
Zhihong Huang China	33	2.5k 0.6×	5.6k 1.5×	1.9k 1.1×	1.6k 1.2×	287 0.2×	135	12.5k
Robert O. Messing United States	58	2.1k 0.5×	5.2k 1.4×	1.1k 0.7×	4.9k 3.5×	385 0.3×	177	10.7k
Kurt R. Brunden United States	44	4.3k 1.1×	3.3k 0.9×	1.7k 1.0×	1.8k 1.3×	321 0.3×	115	8.7k
Yadong Huang United States	63	6.9k 1.7×	5.3k 1.4×	1.9k 1.1×	2.7k 2.0×	712 0.6×	143	13.9k
Masahisa Katsuno Japan	56	1.8k 0.4×	5.9k 1.6×	929 0.5×	4.0k 2.9×	461 0.4×	419	11.6k

Countries citing papers authored by Carmela R. Abraham

Since Specialization

Citations

This map shows the geographic impact of Carmela R. Abraham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Carmela R. Abraham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Carmela R. Abraham more than expected).

Fields of papers citing papers by Carmela R. Abraham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Carmela R. Abraham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Carmela R. Abraham. The network helps show where Carmela R. Abraham may publish in the future.

Co-authorship network of co-authors of Carmela R. Abraham

This figure shows the co-authorship network connecting the top 25 collaborators of Carmela R. Abraham. A scholar is included among the top collaborators of Carmela R. Abraham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Carmela R. Abraham. Carmela R. Abraham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sánchez‐de‐Diego, Cristina, Carmela R. Abraham, Assumpció Bosch, et al.. (2025). Long-term effects of s-KL treatment in wild-type mice: Enhancing longevity, physical well-being, and neurological resilience. Molecular Therapy. 33(4). 1449–1465. 2 indexed citations

Bennett, Estelle R., Nadav Yayon, David A. Bennett, et al.. (2024). Knockout of the longevity gene Klotho perturbs aging and Alzheimer’s disease-linked brain microRNAs and tRNA fragments. Communications Biology. 7(1). 720–720. 11 indexed citations

Wolf, Erika J., Mark W. Logue, Xiang Zhao, et al.. (2020). PTSD and the klotho longevity gene: Evaluation of longitudinal effects on inflammation via DNA methylation. Psychoneuroendocrinology. 117. 104656–104656. 12 indexed citations

Rudy, Melissa A., et al.. (2020). A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone. The FASEB Journal. 34(6). 7234–7246. 6 indexed citations

Jarad, George, Renuga Devi Rajaram, Joseph M. Rutkowski, et al.. (2019). Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress. The FASEB Journal. 34(2). 2087–2104. 24 indexed citations

Zeldich, Ella, Ci-Di Chen, Robin L. Avila, Satish Medicetty, & Carmela R. Abraham. (2015). The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination. Journal of Molecular Neuroscience. 57(2). 185–196. 48 indexed citations

Zeldich, Ella, Ci-Di Chen, Teresa A. Colvin, et al.. (2014). The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System. Journal of Biological Chemistry. 289(35). 24700–24715. 173 indexed citations

Chen, Ci-Di, Jacob A. Sloane, Hu Li, et al.. (2013). The Antiaging Protein Klotho Enhances Oligodendrocyte Maturation and Myelination of the CNS. Journal of Neuroscience. 33(5). 1927–1939. 129 indexed citations

Abraham, Carmela R., Ci-Di Chen, & Gwendalyn D. King. (2010). P3‐469: Development of Klotho enhancers as novel therapeutics for Alzheimer's disease. Alzheimer s & Dementia. 6(4S_Part_19). 1 indexed citations

10.

Chen, Ci-Di, Sonia Podvin, E Gillespie, Susan E. Leeman, & Carmela R. Abraham. (2007). Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proceedings of the National Academy of Sciences. 104(50). 19796–19801. 463 indexed citations

11.

Hinman, Jason D., et al.. (2007). Age‐dependent accumulation of ubiquitinated 2′,3′‐cyclic nucleotide 3′‐phosphodiesterase in myelin lipid rafts. Glia. 56(1). 118–133. 33 indexed citations

12.

Duce, James A., Sonia Podvin, William Hollander, et al.. (2007). Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey. Glia. 56(1). 106–117. 108 indexed citations

13.

Chen, Ci-Di, et al.. (2006). Visualization of APP dimerization and APP‐Notch2 heterodimerization in living cells using bimolecular fluorescence complementation. Journal of Neurochemistry. 97(1). 30–43. 51 indexed citations

14.

Farrer, Lindsay A., Carmela R. Abraham, Jonathan L. Haines, et al.. (1998). Association between bleomycin hydrolase and Alzheimer's disease in caucasians. Annals of Neurology. 44(5). 808–811. 29 indexed citations

15.

Aleshkov, Sergei, Carmela R. Abraham, & Vassilis I. Zannis. (1997). Interaction of Nascent ApoE2, ApoE3, and ApoE4 Isoforms Expressed in Mammalian Cells with Amyloid Peptide β (1−40). Relevance to Alzheimer's Disease. Biochemistry. 36(34). 10571–10580. 118 indexed citations

16.

Mucke, Lennart, Carmela R. Abraham, & Eliezer Masliah. (1996). Neurotrophic and Neuroprotective Effects of hAPP in Transgenic Micea. Annals of the New York Academy of Sciences. 777(1). 82–88. 77 indexed citations

17.

Mucke, Lennart, Eliezer Masliah, William B. Johnson, et al.. (1994). Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice. Brain Research. 666(2). 151–167. 234 indexed citations

18.

Campbell, Iain L., Carmela R. Abraham, Eliezer Masliah, et al.. (1993). Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.. Proceedings of the National Academy of Sciences. 90(21). 10061–10065. 861 indexed citations breakdown →

19.

Abraham, Carmela R.. (1989). Potential roles of protease inhibitors in Alzheimer's disease. Neurobiology of Aging. 10(5). 463–465. 14 indexed citations

20.

Kirschner, Daniel A., Carmela R. Abraham, & D. J. Selkoe. (1986). X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation.. Proceedings of the National Academy of Sciences. 83(2). 503–507. 458 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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