Xi‐Ping Huang

27.6k total citations · 6 hit papers
195 papers, 12.2k citations indexed

About

Xi‐Ping Huang is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Biomaterials. According to data from OpenAlex, Xi‐Ping Huang has authored 195 papers receiving a total of 12.2k indexed citations (citations by other indexed papers that have themselves been cited), including 112 papers in Molecular Biology, 82 papers in Cellular and Molecular Neuroscience and 19 papers in Biomaterials. Recurrent topics in Xi‐Ping Huang's work include Receptor Mechanisms and Signaling (77 papers), Neuropeptides and Animal Physiology (37 papers) and Neuroscience and Neuropharmacology Research (25 papers). Xi‐Ping Huang is often cited by papers focused on Receptor Mechanisms and Signaling (77 papers), Neuropeptides and Animal Physiology (37 papers) and Neuroscience and Neuropharmacology Research (25 papers). Xi‐Ping Huang collaborates with scholars based in United States, China and Canada. Xi‐Ping Huang's co-authors include Bryan L. Roth, Vsevolod Katritch, Vadim Cherezov, Raymond C. Stevens, John D. McCorvy, Philippe Giguère, Gye Won Han, Huixian Wu, Eyal Vardy and Aaron A. Thompson and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Xi‐Ping Huang

183 papers receiving 12.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

2016 1.1k citations Xi‐Ping Huang et al. Nature profile →
Structure of the human κ-opioid receptor in complex with JDTic

2012 718 citations Daniel Wacker, Vsevolod Katritch et al. Nature profile →
Structure-based discovery of opioid analgesics with reduced side effects

2016 697 citations John D. McCorvy, Xi‐Ping Huang et al. Nature profile →
Structural Features for Functional Selectivity at Serotonin Receptors

2013 543 citations Daniel Wacker, Chong Wang et al. Science profile →
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

2015 519 citations Maria F. Sassano, Xi‐Ping Huang et al. profile →
Synthon-based ligand discovery in virtual libraries of over 11 billion compounds

2021 254 citations Yongfeng Liu, Xi‐Ping Huang et al. Nature profile →

Peers

Countries citing papers authored by Xi‐Ping Huang

Since Specialization

Citations

This map shows the geographic impact of Xi‐Ping Huang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xi‐Ping Huang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xi‐Ping Huang more than expected).

Fields of papers citing papers by Xi‐Ping Huang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xi‐Ping Huang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xi‐Ping Huang. The network helps show where Xi‐Ping Huang may publish in the future.

Co-authorship network of co-authors of Xi‐Ping Huang

This figure shows the co-authorship network connecting the top 25 collaborators of Xi‐Ping Huang. A scholar is included among the top collaborators of Xi‐Ping Huang based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xi‐Ping Huang. Xi‐Ping Huang is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Ferulic acid in Chaihu Shugan San modulates depression-like behavior, endothelial and gastrointestinal dysfunction in rats via the Ghrl-Edn1/Mecp2/P-mTOR/VEGFA pathway: A multi-omics study 2025 ·Journal of Ethnopharmacology ·Min Xu, (unknown), Li Zhou, (unknown), Hao Liu, (unknown), Jing‐Hua Tian, (unknown), (unknown), Xi‐Ping Huang	0
2	A multi-level monitoring mechanism for inland ships sewage based on software-defined cloud-edge-end collaborative architecture 2025 ·Ocean & Coastal Management ·Dong Han, (unknown), Yuanqiao Wen, (unknown), (unknown), Xi‐Ping Huang	1
3	Identification of serum metabolites associated with aristolochic acid nephropathy severity and insights into the underlying mechanism 2024 ·Toxicology Letters ·Xinhui Liu, Peng Yu, (unknown), Xi‐Ping Huang, (unknown), (unknown), Jiandong Lu	1
4	An experimental investigation on freeze-thaw resistance of fiber-reinforced red mud-slag based geopolymer 2024 ·Case Studies in Construction Materials ·Yongbao Wang, Xi‐Ping Huang, (unknown), Xiao Zhang, (unknown)	9
5	A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state 2024 ·Nature Communications ·(unknown), B. Krumm, Nicholas J. Kapolka, W.H. Ludlam, Meng Cui, (unknown), (unknown), (unknown), (unknown), (unknown), Ning Ma, Xi‐Ping Huang, Jonathan F. Fay, Nagarajan Vaidehi, Alan V. Smrcka, Paul A. Slesinger, Diomedes E. Logothetis, Kirill A. Martemyanov, Bryan L. Roth, Henrik Dohlman	5
6	Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists 2023 ·The EMBO Journal ·(unknown), Yongfeng Liu, Saheem A. Zaidi, Lingyi Xu, (unknown), Anqi Chen, Jiangtao Guo, Xi‐Ping Huang, Bryan L. Roth, Vsevolod Katritch, Vadim Cherezov, Haitao Zhang	24
7	Docking for EP4R antagonists active against inflammatory pain 2023 ·Nature Communications ·Stefan Gahbauer, (unknown), Joao Bráz, Veronica Craik, Hye Jin Kang, Xiaobo Wan, Xi‐Ping Huang, Christian B. Billesbølle, Yongfeng Liu, Tao Che, Ishan Deshpande, (unknown), Elissa A. Fink, Ivan S. Kondratov, Yurii S. Moroz, John J. Irwin, Allan I. Basbaum, Bryan L. Roth, Brian K. Shoichet	19
8	De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep-Learning Framework 2023 ·Journal of Chemical Information and Modeling ·(unknown), Davide Provasi, Xing Qiu, H. Ümit Kanıskan, Xi‐Ping Huang, Jeffrey F. DiBerto, João Marcelo Lamim Ribeiro, Jian Jin, Bryan L. Roth, Marta Filizola	10
9	Molecular basis for selective activation of DREADD-based chemogenetics 2022 ·Nature ·Shicheng Zhang, Ryan H. Gumpper, Xi‐Ping Huang, Yongfeng Liu, B. Krumm, Can Cao, Jonathan F. Fay, Bryan L. Roth	49
10	Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor 2021 ·Cell Research ·Youwen Zhuang, B. Krumm, Huibing Zhang, X. Edward Zhou, Yue Wang, Xi‐Ping Huang, Yongfeng Liu, Xi Cheng, Yi Jiang, Hualiang Jiang, Cheng Zhang, Wei Yi, Bryan L. Roth, Yan Zhang, H. Eric Xu	62
11	Structures of the σ2 receptor enable docking for bioactive ligand discovery 2021 ·Nature ·Assaf Alon, Jiankun Lyu, João M. Bráz, Tia A. Tummino, Veronica Craik, Matthew J. O’Meara, Chase M. Webb, Dmytro S. Radchenko, Yurii S. Moroz, Xi‐Ping Huang, Yongfeng Liu, Bryan L. Roth, John J. Irwin, Allan I. Basbaum, Brian K. Shoichet, Andrew C. Kruse	135
12	Structures of the human dopamine D3 receptor-Gi complexes 2021 ·Molecular Cell ·Peiyu Xu, Sijie Huang, Chunyou Mao, B. Krumm, X. Edward Zhou, Yangxia Tan, Xi‐Ping Huang, Yongfeng Liu, Dandan Shen, Yi Jiang, Xuekui Yu, Hualiang Jiang, Karsten Melcher, Bryan L. Roth, Xi Cheng, Yan Zhang, H. Eric Xu	57
13	Structure-based discovery of potent and selective melatonin receptor agonists 2020 ·eLife ·Nilkanth Patel, Xi‐Ping Huang, Jessica M. Grandner, Linda C. Johansson, Benjamin Stauch, John D. McCorvy, Yongfeng Liu, Bryan L. Roth, Vsevolod Katritch	25
14	Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands 2020 ·Journal of Medicinal Chemistry ·Liang Tan, Qingtong Zhou, Wenzhong Yan, Jian Sun, Alan P. Kozikowski, Suwen Zhao, Xi‐Ping Huang, Jianjun Cheng	16
15	The activities of drug inactive ingredients on biological targets 2020 ·Science ·Joshua Pottel, Duncan Armstrong, Ling Zou, Alexander Fekete, Xi‐Ping Huang, Hayarpi Torosyan, Dallas Bednarczyk, Steven Whitebread, Barun Bhhatarai, Guiqing Liang, Hong Jin, S. Nassir Ghaemi, Samuel T. Slocum, Katalin Lukács, John J. Irwin, Ellen L. Berg, Kathleen M. Giacomini, Bryan L. Roth, Brian K. Shoichet, László Urbán	63
16	Exploring Halogen Bonds in 5-Hydroxytryptamine 2B Receptor–Ligand Interactions 2018 ·ACS Medicinal Chemistry Letters ·Yu Zhou, Yuanxun Wang, Pengfei Li, Xi‐Ping Huang, Xiangbing Qi, Yunfei Du, Niu Huang	18
17	Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivo 2017 ·JCI Insight ·Xi‐Ping Huang, Tao Che, Thomas J. Mangano, Valerie Le Rouzic, Ying‐Xian Pan, Michael D. Cameron, Michael H. Baumann, Gavril W. Pasternak, Bryan L. Roth	17
18	Structural Features for Functional Selectivity at Serotonin Receptors breakdown → 2013 ·Science ·Daniel Wacker, Chong Wang, Vsevolod Katritch, Gye Won Han, Xi‐Ping Huang, Eyal Vardy, John D. McCorvy, Yi Jiang, Meihua Chu, Fai Siu, Wei Liu, H. Eric Xu, Vadim Cherezov, Bryan L. Roth, Raymond C. Stevens	543
19	Discovery of β-Arrestin–Biased Dopamine D ₂ Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy 2011 ·Proceedings of the National Academy of Sciences ·John Allen, Julianne M. Yost, Vincent Setola, Xin Chen, Maria F. Sassano, Meng Chen, Sean M. Peterson, Prem N. Yadav, Xi‐Ping Huang, Bo Feng, Niels Jensen, Xin Che, Xu Bai, Stephen V. Frye, William C. Wetsel, Marc G. Caron, Jonathan A. Javitch, Bryan L. Roth, Jian Jin	281
20	Identification of Human Ether-à-go-go Related Gene Modulators by Three Screening Platforms in an Academic Drug-Discovery Setting 2010 ·Assay and Drug Development Technologies ·Xi‐Ping Huang, Thomas J. Mangano, Sandy Hufeisen, Vincent Setola, Bryan L. Roth	58

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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